Polymorphic or mutational markers

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CPC
C12Q2600/156

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CCHEMISTRY METALLURGY C12Biochemistry C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES OR MICRO-ORGANISMS COMPOSITIONS OR TEST PAPERS THEREFOR PROCESSES OF PREPARING SUCH COMPOSITIONS CONDITION RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES C12Q2600/00Oligonucleotides characterized by their use

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C12Q2600/156Polymorphic or mutational markers

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Patents Grantslast 30 patents

Information Patent Grant
Methods, systems, compositions, kits, apparatus and computer-readab...
- Patent number 12,338,496
- Issue date Jun 24, 2025
- Life Technologies Corporation
- Kelli Bramlett
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Single-stranded break detection in double-stranded DNA
- Patent number 12,338,486
- Issue date Jun 24, 2025
- Massachusetts Institute of Technology
- Sarah DiIorio
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods of diagnosing and treating Alzheimer's disease
- Patent number 12,338,495
- Issue date Jun 24, 2025
- Sanford Burnham Prebys Medical Discovery Institute
- Jerold Chun
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Resistance genes to Agrobacterium tumefaciens infections in rose
- Patent number 12,336,494
- Issue date Jun 24, 2025
- Dümmen Group B.V.
- Camillo Bérénos
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
System and method for generating a gestational disorder nourishment...
- Patent number 12,340,893
- Issue date Jun 24, 2025
- KPN INNOVATIONS LLC
- Kenneth Neumann
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for assessing risk of developing a viral disease using a ge...
- Patent number 12,331,357
- Issue date Jun 17, 2025
- PML Screening, LLC
- Eli Hatchwell
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Neoantigens and uses thereof for treating cancer
- Patent number 12,331,359
- Issue date Jun 17, 2025
- Icahn School of Medicine at Mount Sinai
- Marta Luksza
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods and systems for identification and prioritization of mutati...
- Patent number 12,331,361
- Issue date Jun 17, 2025
- Personal Genome Diagnostics Inc.
- Victor Velculescu
- G01 - MEASURING TESTING
Information Patent Grant
Gene and mutations thereof associated with seizure and movement dis...
- Patent number 12,331,358
- Issue date Jun 17, 2025
- The University of Melbourne
- Sarah Elizabeth Heron
- G01 - MEASURING TESTING
Information Patent Grant
Method for diagnosing cancer and predicting type of cancer based on...
- Patent number 12,331,364
- Issue date Jun 17, 2025
- GC GENOME CORPORATION
- JungKyoon Choi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Detecting breast cancer
- Patent number 12,325,878
- Issue date Jun 10, 2025
- Mayo Foundation for Medical Education and Research
- David A. Ahlquist
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Use of beta-catenin as a biomarker for treating cancers using anti-...
- Patent number 12,319,730
- Issue date Jun 3, 2025
- Leap Therapeutics, Inc.
- Michael H. Kagey
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for identifying progression of a primary melanoma
- Patent number 12,319,970
- Issue date Jun 3, 2025
- The Brigham & Women's Hospital, Inc.
- Thomas S. Kupper
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for monitoring residual disease
- Patent number 12,319,972
- Issue date Jun 3, 2025
- Guardent Health, Inc.
- AmirAli Talasaz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
System and method for generating a geographically linked nourishmen...
- Patent number 12,322,491
- Issue date Jun 3, 2025
- KPN Innovations, LLC
- Kenneth Neumann
- G06 - COMPUTING CALCULATING COUNTING
Information Patent Grant
Gene mutations and copy number alterations of EGFR, KRAS and MET
- Patent number 12,319,968
- Issue date Jun 3, 2025
- GUARDANT HEALTH, INC.
- Scott Kopetz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Rebaudioside M-rich stevia plant
- Patent number 12,317,798
- Issue date Jun 3, 2025
- Suntory Holdings Limited
- Kazunari Iwaki
- A23 - FOODS OR FOODSTUFFS THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Information Patent Grant
Detection and digital quantitation of multiple targets
- Patent number 12,319,964
- Issue date Jun 3, 2025
- Countable Labs, Inc.
- Eleen Yee Lam Shum
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for minimizing nornicotine synthesis in to...
- Patent number 12,310,324
- Issue date May 27, 2025
- North Carolina State University
- Ralph E. Dewey
- A24 - TOBACCO CIGARS CIGARETTES SMOKERS' REQUISITES
Information Patent Grant
Alzheimer's disease personalized medicine
- Patent number 12,312,639
- Issue date May 27, 2025
- i2Dx, Inc.
- Janos Redei
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Analysis of nucleic acid sequences
- Patent number 12,312,640
- Issue date May 27, 2025
- 10X GENOMICS, INC.
- Benjamin Hindson
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for using engineered deubiquitinases for p...
- Patent number 12,312,618
- Issue date May 27, 2025
- The Trustees of Columbia University In the City of New York
- Henry M. Colecraft
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for identifying whether a diploid potato is self-compatible
- Patent number 12,305,222
- Issue date May 20, 2025
- YUNNAN NORMAL UNIVERSITY
- Ling Ma
- A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
Information Patent Grant
Methods and systems for selection and treatment of patients with in...
- Patent number 12,305,236
- Issue date May 20, 2025
- Cedars-Sinai Medical Center
- Janine Bilsborough
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods and related aspects for quantitative polymerase chain react...
- Patent number 12,305,242
- Issue date May 20, 2025
- The Johns Hopkins University
- Tza-Huei Jeff Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for treatment of thyroid cancer
- Patent number 12,305,238
- Issue date May 20, 2025
- Veracyte, Inc.
- Giulia C. Kennedy
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for simultaneous amplification of target loci
- Patent number 12,305,229
- Issue date May 20, 2025
- Natera, Inc.
- Bernhard Zimmermann
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for detecting immune cell DNA and monitoring immune system
- Patent number 12,305,235
- Issue date May 20, 2025
- Natera, Inc.
- Dina M. Hafez
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Analysis of nucleic acid sequences
- Patent number 12,305,239
- Issue date May 20, 2025
- 10X GENOMICS, INC.
- Solongo B. Ziraldo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
EML4-ALK translocations in lung cancer
- Patent number 12,305,241
- Issue date May 20, 2025
- Quest Diagnostics Investments LLC
- Heather R. Sanders
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
METHODS OF DIAGNOSING AND TREATING CD55 DEFICIENCY, HYPERACTIVATION...
- Publication number 20250207198
- Publication date Jun 26, 2025
- The USA, as represented by the Secretary, Department of Health and Human Serv...
- Michael J. Lenardo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MULTIPLEX CELLULAR REFERENCE MATERIALS
- Publication number 20250207200
- Publication date Jun 26, 2025
- LGC Clinical Diagnostics, Inc.
- Catherine Huang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TRANSCRIPTION-DEPENDENT DIRECTED EVOLUTION OF AAV CAPSIDS HAVING EN...
- Publication number 20250206783
- Publication date Jun 26, 2025
- Capsigen Inc.
- Hiroyuki NAKAI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 28240606
- Publication number 20250204448
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 29120934
- Publication number 20250204454
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 24290269
- Publication number 20250204459
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SPATIALLY ENCODED BIOLOGICAL ASSAYS
- Publication number 20250207183
- Publication date Jun 26, 2025
- Prognosys Biosciences, Inc.
- Mark S. CHEE
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
SYSTEM, METHOD, AND COMPUTER READABLE MEDIUM FOR DIAGNOSING AN INDI...
- Publication number 20250207201
- Publication date Jun 26, 2025
- University of Virginia Patent Foundation
- Robin A. Felder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 29240924
- Publication number 20250204465
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PROCESS FOR DETECTING A TARGET NUCLEIC ACID
- Publication number 20250207181
- Publication date Jun 26, 2025
- ALMA MATER STUDIORUM - Universita' di Bologna (90%)
- Luca Prodi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
REAGENT, KIT, AND METHOD FOR DETECTING PIG ECONOMIC TRAIT-ASSOCIATE...
- Publication number 20250207205
- Publication date Jun 26, 2025
- AGRICULTURAL GENOMICS INSTITUTE AT SHENZHEN, CHINESE ACADEMY OF AGRICULTURAL...
- Kui LI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 25310108
- Publication number 20250204446
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 24180206
- Publication number 20250204463
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 21250789
- Publication number 20250204468
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Markers for Soybean Peroxidase
- Publication number 20250204349
- Publication date Jun 26, 2025
- BASF Agricultural Solutions US LLC
- Xiaolei Wu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR USING MOSAICISM IN NUCLEIC ACIDS SAMPLED DISTAL TO THEI...
- Publication number 20250207204
- Publication date Jun 26, 2025
- Personalis, Inc.
- John West
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Markers for Iron Deficiency Chlorosis
- Publication number 20250207208
- Publication date Jun 26, 2025
- BASF Agricultural Solutions US LLC
- Jieqing Ping
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MARKERS FOR PHYTOPHTHORA RESISTANCE
- Publication number 20250204348
- Publication date Jun 26, 2025
- BASF Agricultural Solutions US LLC
- Xiaolei Wu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 20130716
- Publication number 20250204449
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 20230934
- Publication number 20250204455
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 23010103
- Publication number 20250204466
- Publication date Jun 26, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TOMATO VARIETY NUN 08605 TOF
- Publication number 20250204478
- Publication date Jun 26, 2025
- Nunhems BV
- Pascal WANTEN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SPATIALLY ENCODED BIOLOGICAL ASSAYS
- Publication number 20250207182
- Publication date Jun 26, 2025
- Prognosys Biosciences, Inc.
- Mark S. CHEE
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
Treatment Of Liver Disease With Mitochondrial Glycerol-3-Phosphate...
- Publication number 20250197866
- Publication date Jun 19, 2025
- Regeneron Pharmaceuticals, Inc.
- Luca Andrea Lotta
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ONCOGENIC STRUCTURAL VARIANTS
- Publication number 20250197943
- Publication date Jun 19, 2025
- Arima Genomics, Inc.
- Anthony Schmitt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 26160905
- Publication number 20250194525
- Publication date Jun 19, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS OF SELECTING AND TREATING CANCER SUBJECTS THAT ARE CANDIDAT...
- Publication number 20250197942
- Publication date Jun 19, 2025
- Arima Genomics, Inc.
- Anthony Schmitt
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SOYBEAN CULTIVAR 23140546
- Publication number 20250194524
- Publication date Jun 19, 2025
- MS TECHNOLOGIES, LLC
- Justin T. MASON
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PEPPER HYBRID SVPZ4566 AND PARENTS THEREOF
- Publication number 20250194549
- Publication date Jun 19, 2025
- SEMINIS VEGETABLE SEEDS, INC.
- Brian JUST
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
RET GENE FUSIONS AND USES THEREOF
- Publication number 20250197934
- Publication date Jun 19, 2025
- Foundation Medicine, Inc.
- Erica GORNSTEIN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Polymorphic or mutational markers

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Methods, systems, compositions, kits, apparatus and computer-readab...

Single-stranded break detection in double-stranded DNA

Methods of diagnosing and treating Alzheimer's disease

Resistance genes to Agrobacterium tumefaciens infections in rose

System and method for generating a gestational disorder nourishment...

Methods for assessing risk of developing a viral disease using a ge...

Neoantigens and uses thereof for treating cancer

Methods and systems for identification and prioritization of mutati...

Gene and mutations thereof associated with seizure and movement dis...

Method for diagnosing cancer and predicting type of cancer based on...

Detecting breast cancer

Use of beta-catenin as a biomarker for treating cancers using anti-...

Methods for identifying progression of a primary melanoma

Methods for monitoring residual disease

System and method for generating a geographically linked nourishmen...

Gene mutations and copy number alterations of EGFR, KRAS and MET

Rebaudioside M-rich stevia plant

Detection and digital quantitation of multiple targets

Compositions and methods for minimizing nornicotine synthesis in to...

Alzheimer's disease personalized medicine

Analysis of nucleic acid sequences

Compositions and methods for using engineered deubiquitinases for p...

Method for identifying whether a diploid potato is self-compatible

Methods and systems for selection and treatment of patients with in...

Methods and related aspects for quantitative polymerase chain react...

Methods for treatment of thyroid cancer

Methods for simultaneous amplification of target loci

Methods for detecting immune cell DNA and monitoring immune system

Analysis of nucleic acid sequences

EML4-ALK translocations in lung cancer

Patents Applicationslast 30 patents

METHODS OF DIAGNOSING AND TREATING CD55 DEFICIENCY, HYPERACTIVATION...

MULTIPLEX CELLULAR REFERENCE MATERIALS

TRANSCRIPTION-DEPENDENT DIRECTED EVOLUTION OF AAV CAPSIDS HAVING EN...

SOYBEAN CULTIVAR 28240606

SOYBEAN CULTIVAR 29120934

SOYBEAN CULTIVAR 24290269

SPATIALLY ENCODED BIOLOGICAL ASSAYS

SYSTEM, METHOD, AND COMPUTER READABLE MEDIUM FOR DIAGNOSING AN INDI...

SOYBEAN CULTIVAR 29240924

PROCESS FOR DETECTING A TARGET NUCLEIC ACID

REAGENT, KIT, AND METHOD FOR DETECTING PIG ECONOMIC TRAIT-ASSOCIATE...

SOYBEAN CULTIVAR 25310108

SOYBEAN CULTIVAR 24180206

SOYBEAN CULTIVAR 21250789

Markers for Soybean Peroxidase

METHODS FOR USING MOSAICISM IN NUCLEIC ACIDS SAMPLED DISTAL TO THEI...

Markers for Iron Deficiency Chlorosis

MARKERS FOR PHYTOPHTHORA RESISTANCE

SOYBEAN CULTIVAR 20130716

SOYBEAN CULTIVAR 20230934

SOYBEAN CULTIVAR 23010103

TOMATO VARIETY NUN 08605 TOF

SPATIALLY ENCODED BIOLOGICAL ASSAYS

Treatment Of Liver Disease With Mitochondrial Glycerol-3-Phosphate...

ONCOGENIC STRUCTURAL VARIANTS

SOYBEAN CULTIVAR 26160905

METHODS OF SELECTING AND TREATING CANCER SUBJECTS THAT ARE CANDIDAT...

SOYBEAN CULTIVAR 23140546

PEPPER HYBRID SVPZ4566 AND PARENTS THEREOF

RET GENE FUSIONS AND USES THEREOF