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Purification or manufacturing processes for gene therapy compositions
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A61K48/0091
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HUMAN NECESSITIES
A61
Medical science
A61K
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
A61K48/00
Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases Gene therapy
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A61K48/0091
Purification or manufacturing processes for gene therapy compositions
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Patents Grants
last 30 patents
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Patent Grant
Method for delivering RNA to neurons to treat herpes infections
Patent number
12,156,919
Issue date
Dec 3, 2024
University of Florida Research Foundation, Incorporated
David C. Bloom
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dry powder composition comprising long-chain RNA
Patent number
12,138,348
Issue date
Nov 12, 2024
CureVac SE
Fabian Johannes Eber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Immunostimulating vector system
Patent number
12,133,898
Issue date
Nov 5, 2024
Provecs Medical GmbH
Frank Schnieders
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid nanoparticle compositions and methods for mRNA delivery
Patent number
12,121,592
Issue date
Oct 22, 2024
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene therapy for recessive dystrophic epidermolysis bullosa using g...
Patent number
12,110,504
Issue date
Oct 8, 2024
The Board of Trustees of the Leland Stanford Junior University
Zurab Siprashvili
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Gene therapy
Patent number
12,059,478
Issue date
Aug 13, 2024
Ospedale San Raffaele S.r.l.
Anna Christina Kajaste-Rudnitski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Treating metastatic cancer and model systems for metastatic disease
Patent number
12,059,480
Issue date
Aug 13, 2024
Memorial Sloan Kettering Cancer Center
Karuna Ganesh
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Nanoparticles comprising protein-polynucleotide complexes and for d...
Patent number
12,036,287
Issue date
Jul 16, 2024
Asklepios Biopharmaceutical, Inc.
Gretchen M. Unger
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Extracellular vesicles for inhalation
Patent number
12,029,821
Issue date
Jul 9, 2024
OMNISPIRANT LIMITED
Gerard Bernard McCauley
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Rapid design, build, test, and learn technologies for identifying a...
Patent number
12,031,128
Issue date
Jul 9, 2024
Battelle Memorial Institute
Anthony D. Duong
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Delivery and use of the CRISPR-CAS systems, vectors and composition...
Patent number
12,018,275
Issue date
Jun 25, 2024
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and systems comprising transfection-competent vesicles...
Patent number
11,980,673
Issue date
May 14, 2024
The University of British Columbia
Blair Leavitt
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Processes of preparing mRNA-loaded lipid nanoparticles
Patent number
11,969,480
Issue date
Apr 30, 2024
Translate Bio, Inc.
Shrirang Karve
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
Nucleic acid loaded extracellular vesicles
Patent number
11,970,718
Issue date
Apr 30, 2024
Carmine Therapeutics Pte. Ltd.
Harvey Lodish
B82 - NANO-TECHNOLOGY
Information
Patent Grant
Compositions and methods for TTR gene editing and treating ATTR amy...
Patent number
11,965,165
Issue date
Apr 23, 2024
Intellia Therapeutics, Inc.
Arti Mahendra Prakash Kanjolia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid nanoparticle compositions and methods for MRNA delivery
Patent number
11,951,180
Issue date
Apr 9, 2024
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid nanoparticle compositions and methods for mRNA delivery
Patent number
11,951,181
Issue date
Apr 9, 2024
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid nanoparticle compositions and methods for MRNA delivery
Patent number
11,951,179
Issue date
Apr 9, 2024
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Vector for gene silencing and replacement and methods of use thereof
Patent number
11,951,184
Issue date
Apr 9, 2024
Wisconsin Alumni Research Foundation
Matthew Michael Millette
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Evolution of TALENs
Patent number
11,913,040
Issue date
Feb 27, 2024
President and Fellows of Harvard College
David R. Liu
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Scalable manufacturing platform for viral vector purification and v...
Patent number
11,878,056
Issue date
Jan 23, 2024
The Children's Hospital of Philadelphia
John Fraser Wright
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
RAAV with chemically modified capsid
Patent number
11,865,185
Issue date
Jan 9, 2024
Centre National de la Recherche Scientifique (Cnrs)
Mathieu Mevel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and systems comprising transfection-competent vesicles...
Patent number
11,865,190
Issue date
Jan 9, 2024
The University of British Columbia
Blair Leavitt
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Analytical HPLC methods
Patent number
11,866,696
Issue date
Jan 9, 2024
ModernaTX, Inc.
William Issa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Electroporation, developmentally-activated cells, pluripotent-like...
Patent number
11,859,168
Issue date
Jan 2, 2024
Christopher B. Reid
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for TTR gene editing and treating ATTR amy...
Patent number
11,795,460
Issue date
Oct 24, 2023
Intellia Therapeutics, Inc.
Arti Mahendra Prakash Kanjolia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for mitochondrial genome editing
Patent number
11,779,657
Issue date
Oct 10, 2023
City of Hope
John Burnett
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Lipid nanoparticle compositions and methods for mRNA delivery
Patent number
11,730,825
Issue date
Aug 22, 2023
Translate Bio, Inc.
Braydon Charles Guild
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Method of increasing the function of an AAV vector
Patent number
11,680,274
Issue date
Jun 20, 2023
The Trustees of the University of Pennsylvania
Luk Vandenberghe
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for modifying a mutant dystrophin gene in...
Patent number
11,666,666
Issue date
Jun 6, 2023
The Regents of the University of California
April D. Pyle
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
PROCESSES OF PREPARING MRNA-LOADED LIPID NANOPARTICLES
Publication number
20240366798
Publication date
Nov 7, 2024
Translate Bio, Inc.
Shrirang Karve
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Application
COMPOSITIONS AND SYSTEMS COMPRISING TRANSFECTION-COMPETENT VESICLES...
Publication number
20240350676
Publication date
Oct 24, 2024
The University of British Columbia
Blair Leavitt
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
COMPOSITIONS AND SYSTEMS COMPRISING TRANSFECTION-COMPETENT VESICLES...
Publication number
20240342315
Publication date
Oct 17, 2024
The University of British Columbia
Blair Leavitt
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
EXTRACELLULAR VESICLES FOR INHALATION
Publication number
20240315980
Publication date
Sep 26, 2024
OMNISPIRANT LIMITED
Gerard Bernard MCCAULEY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
CAPSID VARIANTS AND METHODS OF USING THE SAME
Publication number
20240294578
Publication date
Sep 5, 2024
DYNO THERAPEUTICS, INC.
Sylvain Lapan
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SCALABLE PRODUCTION METHOD FOR AAV
Publication number
20240247237
Publication date
Jul 25, 2024
The Trustees of the University of Pennsylvania
Martin Lock
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONSTRUCTS AND METHODS FOR DELIVERYING MOLECULES VIA VIRAL VECTORS...
Publication number
20240229068
Publication date
Jul 11, 2024
NXGEN VECTOR SOLUTIONS, LLC
Joseph E. Rabinowitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ELECTROPORATION, DEVELOPMENTALLY-ACTIVATED CELLS, PLURIPOTENT-LIKE...
Publication number
20240228941
Publication date
Jul 11, 2024
Christopher B. Reid
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
EVOLUTION OF TALENS
Publication number
20240200044
Publication date
Jun 20, 2024
President and Fellows of Harvard College
David R. Liu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
HSV AMPLICON PACKAGING SYSTEM USING ENGINEERED CELLS
Publication number
20240191243
Publication date
Jun 13, 2024
University of Pittsburgh of the Commonwealth System of Higher Education
Joseph C. Glorioso
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PRODUCTION OF CIRCULAR POLYRIBONUCLEOTIDES IN A EUKARYOTIC SYSTEM
Publication number
20240181079
Publication date
Jun 6, 2024
Flagship Pioneering Innovations VII, LLC
Barry Andrew Martin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHODS OF PREPARATION OF NOVEL PAN TLR ANTAGONISTIC LIPOSOMAL-LNP...
Publication number
20240156733
Publication date
May 16, 2024
Celestial Therapeutics Inc.
Ajay Gupta
B82 - NANO-TECHNOLOGY
Information
Patent Application
Methods and Compositions for Modifying a Mutant Dystrophin Gene in...
Publication number
20240156989
Publication date
May 16, 2024
The Regents of the University of California
April D. Pyle
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR TREATING CLRN1-ASSOCIATED HEARING LOSS...
Publication number
20240139344
Publication date
May 2, 2024
Akouos, Inc.
Emmanuel John Simons
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CONSTRUCTS AND METHODS FOR DELIVERYING MOLECULES VIA VIRAL VECTORS...
Publication number
20240132912
Publication date
Apr 25, 2024
NXGEN VECTOR SOLUTIONS, LLC
Joseph E. Rabinowitz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Method of Increasing the Function of an AAV Vector
Publication number
20240117378
Publication date
Apr 11, 2024
The Trustees of the University of Pennsylvania
Luk VANDENBERGHE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RAPID DESIGN, BUILD, TEST, AND LEARN TECHNOLOGIES FOR IDENTIFYING A...
Publication number
20240117339
Publication date
Apr 11, 2024
Battelle Memorial Institute
Anthony D. DUONG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR PREPARATION OF PLASMID DNA/LIPID PARTICLES WITH DEFINED...
Publication number
20240115513
Publication date
Apr 11, 2024
The Johns Hopkins University
Hai-Quan Mao
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
GENE THERAPY FOR RECESSIVE DYSTROPHIC EPIDERMOLYSIS BULLOSA USING G...
Publication number
20240067926
Publication date
Feb 29, 2024
The Board of Trustees of the Leland Stanford Junior University
Zurab Siprashvili
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
AMINO ALCOHOL IONIZABLE LIPIDS
Publication number
20240041786
Publication date
Feb 8, 2024
NEW JERSEY INSTITUTE OF TECHNOLOGY
Xiaoyang Xu
B82 - NANO-TECHNOLOGY
Information
Patent Application
AMINO ALCOHOL IONIZABLE LIPIDS
Publication number
20240024239
Publication date
Jan 25, 2024
NEW JERSEY INSTITUTE OF TECHNOLOGY
Xiaoyang Xu
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FORMULATIONS FOR SUPRACHOROIDAL ADMINISTRATION SUCH AS GEL FORMULAT...
Publication number
20230414788
Publication date
Dec 28, 2023
Regenxbio Inc.
Jared Bee
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PERFUSION-GUIDED GENE THERAPY FOR IMPROVING CANCER TREATMENT
Publication number
20230414786
Publication date
Dec 28, 2023
Board of Regents, The University of Texas System
Shashank R. Sirsi
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD OF INCREASING THE FUNCTION OF AN AAV VECTOR
Publication number
20230416780
Publication date
Dec 28, 2023
The Trustees of the University of Pennsylvania
Luk VANDENBERGHE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
METHOD OF INCREASING THE FUNCTION OF AN AAV VECTOR
Publication number
20230340532
Publication date
Oct 26, 2023
The Trustees of the University of Pennsylvania
Luk VANDENBERGHE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
Publication number
20230330262
Publication date
Oct 19, 2023
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ADENO-ASSOCIATED VIRUS VIRIONS WITH VARIANT CAPSID AND METHODS OF U...
Publication number
20230321282
Publication date
Oct 12, 2023
The Regents of the University of California
David V. Schaffer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
Publication number
20230293723
Publication date
Sep 21, 2023
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHOD OF INCREASING THE FUNCTION OF AN AAV VECTOR
Publication number
20230287452
Publication date
Sep 14, 2023
The Trustees of the University of Pennsylvania
Luk VANDENBERGHE
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LIPID NANOPARTICLE COMPOSITIONS AND METHODS FOR MRNA DELIVERY
Publication number
20230285592
Publication date
Sep 14, 2023
Translate Bio, Inc.
Frank DeRosa
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...