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Patents Grantslast 30 patents

Information Patent Grant
Methods and processes for non-invasive assessment of genetic variat...
- Patent number 12,112,832
- Issue date Oct 8, 2024
- Sequenom, Inc.
- Cosmin Deciu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Dilution tagging for quantification of biological targets
- Patent number 12,071,651
- Issue date Aug 27, 2024
- BillionToOne, Inc.
- David Tsao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
System and method for cleaning noisy genetic data and determining c...
- Patent number 12,065,703
- Issue date Aug 20, 2024
- Natera, Inc.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for quantifying starch cellulose in corn samples
- Patent number 12,054,767
- Issue date Aug 6, 2024
- Edeniq, Inc.
- David Scott Snyder
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Methods for non-invasive prenatal ploidy calling
- Patent number 12,020,778
- Issue date Jun 25, 2024
- Natera, Inc.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Type I interferon signatures and methods of use
- Patent number 12,009,079
- Issue date Jun 11, 2024
- Janssen Biotech, Inc.
- Matteo Cesaroni
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Method and sensor for detecting L-cystine
- Patent number 11,939,625
- Issue date Mar 26, 2024
- Changsha University of Science & Technology
- Zhong Cao
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for isothermal molecular amplification with nanoparticle-ba...
- Patent number 11,866,775
- Issue date Jan 9, 2024
- Brookhaven Science Associates, LLC
- Oleg Gang
- B82 - NANO-TECHNOLOGY
Information Patent Grant
Kit for determining nucleic acid degradation
- Patent number 11,767,553
- Issue date Sep 26, 2023
- Qiagen, GmbH
- Miroslav Vranes
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Compositions and methods for amplification and detection of hepatit...
- Patent number 11,739,382
- Issue date Aug 29, 2023
- Roche Molecular Systems, Inc.
- Jeffery Fong
- G01 - MEASURING TESTING
Information Patent Grant
Diagnostic control compositions
- Patent number 11,713,491
- Issue date Aug 1, 2023
- University of the Witwatersrand, Johannesburg
- Bavesh Davandara Kana
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Assays and methods for determining microbial resistance
- Patent number 11,708,614
- Issue date Jul 25, 2023
- STRECK LLC
- Maria Torres-Gonzalez
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Molecular assay methods
- Patent number 11,685,957
- Issue date Jun 27, 2023
- Gen-Probe Incorporated
- Scott Higgins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for diagnosing Parkinson's disease using nasal mucus, compos...
- Patent number 11,655,507
- Issue date May 23, 2023
- Research & Business Foundation Sungkyunkwan University
- Yunjong Lee
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Quality assessment of circulating cell-free DNA using multiplexed d...
- Patent number 11,634,761
- Issue date Apr 25, 2023
- The Translational Genomics Research Institute
- Muhammed Murtaza
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Error detection during hybridisation of target double-stranded nucl...
- Patent number 11,629,377
- Issue date Apr 18, 2023
- EVONETIX LTD.
- Matthew James Hayes
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Method for producing cell contained base and method for evaluating...
- Patent number 11,566,273
- Issue date Jan 31, 2023
- Ricoh Company, Ltd.
- Satoshi Izumi
- G01 - MEASURING TESTING
Information Patent Grant
PCR controls
- Patent number 11,555,222
- Issue date Jan 17, 2023
- Oslo Universitetssykehus HF
- Guro E. Lind
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and systems for analyzing guide RNA molecules
- Patent number 11,499,151
- Issue date Nov 15, 2022
- Editas Medicine, Inc.
- Cecilia Fernandez
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for preparing a DNA fraction from a biological sample for a...
- Patent number 11,482,300
- Issue date Oct 25, 2022
- Natera, Inc.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for preparing a DNA fraction from a biological sample for a...
- Patent number 11,450,408
- Issue date Sep 20, 2022
- Natera, Inc.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Method for detecting mycoplasma using mitochondrial DNA as internal...
- Patent number 11,434,527
- Issue date Sep 6, 2022
- The Asan Foundation
- Eun Ju Kang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Oligonucleotides and methods for internal control of eukaryotic DNA...
- Patent number 11,427,862
- Issue date Aug 30, 2022
- CENTRO DI SPERIMENTAZIONE LAIMBURG
- Vicky Oberkofler
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and kits for the detection of powdery mildew
- Patent number 11,414,714
- Issue date Aug 16, 2022
- Bayer S.A.S.
- Patrice Dubournet
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Antimicrobial cartridges and processes for multiplexed antimicrobia...
- Patent number 11,390,900
- Issue date Jul 19, 2022
- SELUX DIAGNOSTICS, INC.
- Eric Stern
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Grant
Microbial population analysis
- Patent number 11,359,249
- Issue date Jun 14, 2022
- IS-DIAGNOSTICS LTD
- Andries Edward Budding
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods and compositions related to prostate cancer therapeutics
- Patent number 11,345,956
- Issue date May 31, 2022
- The Johns Hopkins University
- Jun Luo
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methylated control DNA
- Patent number 11,345,949
- Issue date May 31, 2022
- EXACT Sciences Corporation
- Hatim T. Allawi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Internal amplification control
- Patent number 11,345,952
- Issue date May 31, 2022
- QIAGEN GmbH
- Miroslav Vranes
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Methods for the detection of genomic copy changes in DNA samples
- Patent number 11,319,594
- Issue date May 3, 2022
- Resolution Bioscience, Inc.
- Christopher Raymond
- C40 - COMBINATORIAL CHEMISTRY

Patents Applicationslast 30 patents

Information Patent Application
DILUTION TAGGING FOR QUANTIFICATION OF BIOLOGICAL TARGETS
- Publication number 20240392346
- Publication date Nov 28, 2024
- BillionToOne, Inc.
- David TSAO
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR QUANTIFYING STARCH AND CELLULOSE IN CORN SAMPLES
- Publication number 20240360491
- Publication date Oct 31, 2024
- EdeniQ, Inc.
- David Scott Snyder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING
- Publication number 20240331799
- Publication date Oct 3, 2024
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...
- Publication number 20240301495
- Publication date Sep 12, 2024
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
NUCLEIC ACID DETECTION AND QUANTIFICATION METHOD AND COMPOSITIONS
- Publication number 20240294993
- Publication date Sep 5, 2024
- MICROBIAL DISCOVERY GROUP, LLC
- Michael R. KING
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Systems and Methods for Quantification of Donor-Derived Cell-Free DNA
- Publication number 20240209437
- Publication date Jun 27, 2024
- The Board of Trustees of the Leland Stanford Junior University
- Iwijn De Vlaminck
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ASSAYS AND METHODS FOR DETERMINING MICROBIAL RESISTANCE
- Publication number 20240150850
- Publication date May 9, 2024
- STRECK LLC
- Maria Torres-Gonzalez
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...
- Publication number 20230193387
- Publication date Jun 22, 2023
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DIAGNOSTIC CONTROL COMPOSITIONS
- Publication number 20230127238
- Publication date Apr 27, 2023
- UNIVERSITY OF THE WITWATERSRAND, JOHANNESBURG
- Bavesh Davandara Kana
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD, COMPOSITION AND KIT FOR FLUORESCENT QUANTITATIVE PCR, AND U...
- Publication number 20230035871
- Publication date Feb 2, 2023
- SANSURE BIOTECH INC.
- Lizhong DAI
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD AND KIT FOR DETECTING GENOME EDITING AND APPLICATION THEREOF
- Publication number 20230002817
- Publication date Jan 5, 2023
- SHANDONG UNIVERSITY
- Qilai HUANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHYLATED CONTROL DNA
- Publication number 20220340959
- Publication date Oct 27, 2022
- EXACT SCIENCES CORPORATION
- Hatim T. Allawi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
DETECTION PROBE FOR INTERNAL AMPLIFICATION CONTROL AND KIT INCLUDIN...
- Publication number 20220333176
- Publication date Oct 20, 2022
- QIAGEN GmbH
- Miroslav VRANES
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
LINEARLY-AMPLIFIED INTERNAL CONTROL FOR NUCLEIC ACID AMPLIFICATION...
- Publication number 20220282302
- Publication date Sep 8, 2022
- Genomadix Inc.
- Chris Harder
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PROBES AND METHODS FOR MEASURING TANDEM REPEATS
- Publication number 20220195521
- Publication date Jun 23, 2022
- Arizona Board of Regents on behalf of Arizona State University
- Wayne Frasch
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...
- Publication number 20220195526
- Publication date Jun 23, 2022
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING
- Publication number 20220042103
- Publication date Feb 10, 2022
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...
- Publication number 20220033908
- Publication date Feb 3, 2022
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PRE-AMPLIFICATION ASSAY
- Publication number 20210381031
- Publication date Dec 9, 2021
- Bio-Rad Laboratories, Inc.
- Yanhong Kong
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
USING CELL-FREE DNA FRAGMENT SIZE TO DETERMINE COPY NUMBER VARIATIONS
- Publication number 20210371907
- Publication date Dec 2, 2021
- Verinata Health, Inc.
- Darya I. Chudova
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD OF AND APPARATUS FOR ANALYZING TUMOR SUBCLONES
- Publication number 20210254141
- Publication date Aug 19, 2021
- Seoul National University R&DB Foundation
- Sun KIM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR QUANTIFYING STARCH CELLULOSE IN CORN SAMPLES
- Publication number 20210246486
- Publication date Aug 12, 2021
- EdeniQ, Inc.
- David Scott Snyder
- B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information Patent Application
Methods and Systems for Measuring Plasma Renin Activity
- Publication number 20210246085
- Publication date Aug 12, 2021
- Laboratory Corporation of America Holdings
- William O. Slade
- C07 - ORGANIC CHEMISTRY
Information Patent Application
MOLECULAR ASSAY METHODS
- Publication number 20210198750
- Publication date Jul 1, 2021
- Gen-Probe Incorporated
- Scott Higgins
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR NORMALIZATION AND QUANTIFICATION OF SEQUENCING DATA
- Publication number 20210180112
- Publication date Jun 17, 2021
- BioFire Diagnostics, LLC
- Kate Mariel Broadbent
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ASSAYS TO DETERMINE DNA METHYLATION AND DNA METHYLATION MARKERS OF...
- Publication number 20210164031
- Publication date Jun 3, 2021
- ZYMO RESEARCH CORPORATION
- Wei GUO
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...
- Publication number 20210155988
- Publication date May 27, 2021
- NATERA, INC.
- Matthew Rabinowitz
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHOD AND SENSOR FOR DETECTING L-CYSTINE
- Publication number 20210123093
- Publication date Apr 29, 2021
- Changsha University of Science & Technology
- Zhong CAO
- G01 - MEASURING TESTING
Information Patent Application
METHOD FOR DETECTING MYCOPLASMA USING MITOCHONDRIAL DNA AS INTERNA...
- Publication number 20210115505
- Publication date Apr 22, 2021
- THE ASAN FOUNDATION
- Eun Ju KANG
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
Quantification of transplant-derived circulating cell-free DNA in t...
- Publication number 20210115506
- Publication date Apr 22, 2021
- Iwijn De Vlaminck
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Reactions characterised by their quantitative nature

Industry

Parent Industries

Current Industry

Sub Industries

Patents Grantslast 30 patents

Methods and processes for non-invasive assessment of genetic variat...

Dilution tagging for quantification of biological targets

System and method for cleaning noisy genetic data and determining c...

Methods for quantifying starch cellulose in corn samples

Methods for non-invasive prenatal ploidy calling

Type I interferon signatures and methods of use

Method and sensor for detecting L-cystine

Methods for isothermal molecular amplification with nanoparticle-ba...

Kit for determining nucleic acid degradation

Compositions and methods for amplification and detection of hepatit...

Diagnostic control compositions

Assays and methods for determining microbial resistance

Molecular assay methods

Method for diagnosing Parkinson's disease using nasal mucus, compos...

Quality assessment of circulating cell-free DNA using multiplexed d...

Error detection during hybridisation of target double-stranded nucl...

Method for producing cell contained base and method for evaluating...

PCR controls

Methods and systems for analyzing guide RNA molecules

Methods for preparing a DNA fraction from a biological sample for a...

Methods for preparing a DNA fraction from a biological sample for a...

Method for detecting mycoplasma using mitochondrial DNA as internal...

Oligonucleotides and methods for internal control of eukaryotic DNA...

Methods and kits for the detection of powdery mildew

Antimicrobial cartridges and processes for multiplexed antimicrobia...

Microbial population analysis

Methods and compositions related to prostate cancer therapeutics

Methylated control DNA

Internal amplification control

Methods for the detection of genomic copy changes in DNA samples

Patents Applicationslast 30 patents

DILUTION TAGGING FOR QUANTIFICATION OF BIOLOGICAL TARGETS

METHODS FOR QUANTIFYING STARCH AND CELLULOSE IN CORN SAMPLES

METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...

NUCLEIC ACID DETECTION AND QUANTIFICATION METHOD AND COMPOSITIONS

Systems and Methods for Quantification of Donor-Derived Cell-Free DNA

ASSAYS AND METHODS FOR DETERMINING MICROBIAL RESISTANCE

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...

DIAGNOSTIC CONTROL COMPOSITIONS

METHOD, COMPOSITION AND KIT FOR FLUORESCENT QUANTITATIVE PCR, AND U...

METHOD AND KIT FOR DETECTING GENOME EDITING AND APPLICATION THEREOF

METHYLATED CONTROL DNA

DETECTION PROBE FOR INTERNAL AMPLIFICATION CONTROL AND KIT INCLUDIN...

LINEARLY-AMPLIFIED INTERNAL CONTROL FOR NUCLEIC ACID AMPLIFICATION...

PROBES AND METHODS FOR MEASURING TANDEM REPEATS

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...

METHODS FOR NON-INVASIVE PRENATAL PLOIDY CALLING

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...

PRE-AMPLIFICATION ASSAY

USING CELL-FREE DNA FRAGMENT SIZE TO DETERMINE COPY NUMBER VARIATIONS

METHOD OF AND APPARATUS FOR ANALYZING TUMOR SUBCLONES

METHODS FOR QUANTIFYING STARCH CELLULOSE IN CORN SAMPLES

Methods and Systems for Measuring Plasma Renin Activity

MOLECULAR ASSAY METHODS

METHODS FOR NORMALIZATION AND QUANTIFICATION OF SEQUENCING DATA

ASSAYS TO DETERMINE DNA METHYLATION AND DNA METHYLATION MARKERS OF...

SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING C...

METHOD AND SENSOR FOR DETECTING L-CYSTINE

METHOD FOR DETECTING MYCOPLASMA USING MITOCHONDRIAL DNA AS INTERNA...

Quantification of transplant-derived circulating cell-free DNA in t...