TREA

Spatial arrangement of the modifications

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CCHEMISTRY METALLURGY C12Biochemistry C12NMICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA C12N2310/00Structure or type of the nucleic acid

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C12N2310/34Spatial arrangement of the modifications
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Patents Grantslast 30 patents

  • Information Patent Grant

    Chemically modified single-stranded rna-editing oligonucleotides
    • Patent number 12,203,072
    • Issue date Jan 21, 2025
    • ProQR Therapeutics II B.V.
    • Janne Juha Turunen
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    C5a binding nucleic acids
    • Patent number 12,188,021
    • Issue date Jan 7, 2025
    • APTARION biotech AG
    • Kai Hohlig
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Compounds and methods for modulating ATXN1
    • Patent number 12,180,479
    • Issue date Dec 31, 2024
    • Ionis Pharmaceuticals, Inc.
    • Susan M. Freier
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Angelman syndrome antisense treatment
    • Patent number 12,180,480
    • Issue date Dec 31, 2024
    • The Texas A&M University System
    • Scott Victor Dindot
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Fully stabilized asymmetric siRNA
    • Patent number 12,173,286
    • Issue date Dec 24, 2024
    • UNIVERSITY OF MASSACHUSETTS
    • Anastasia Khvorova
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified guide RNAs
    • Patent number 12,173,284
    • Issue date Dec 24, 2024
    • Intellia Therapeutics, Inc.
    • Amy Madison Rhoden Smith
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modulators of APOL1 expression
    • Patent number 12,168,766
    • Issue date Dec 17, 2024
    • Astrazeneca AB
    • Susan M. Freier
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified double-stranded RNA agents
    • Patent number 12,168,767
    • Issue date Dec 17, 2024
    • Alnylam Pharmaceuticals, Inc.
    • Martin Maier
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
    • Patent number 12,163,132
    • Issue date Dec 10, 2024
    • Children's National Medical Center
    • Yi-Wen Chen
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Antisense oligonucleotides to restore dysferlin protein expression...
    • Patent number 12,163,129
    • Issue date Dec 10, 2024
    • University of Massachusetts
    • Robert H. Brown
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Compositions and methods for modulating neuronal excitability and m...
    • Patent number 12,163,130
    • Issue date Dec 10, 2024
    • Icahn School of Medicine at Mount Sinai
    • Anne Schaefer
    • A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
  • Information Patent Grant

    Oligonucleotides for modulating Tau expression
    • Patent number 12,163,131
    • Issue date Dec 10, 2024
    • HOFFMANN-LA ROCHE INC.
    • Peter Hagedorn
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modulating the cellular stress response
    • Patent number 12,157,888
    • Issue date Dec 3, 2024
    • The General Hospital Corporation
    • Jeannie T. Lee
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modulators of MALAT1 expression
    • Patent number 12,157,890
    • Issue date Dec 3, 2024
    • Ionis Pharmaceuticals, Inc.
    • Susan M. Freier
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Selective antisense compounds and uses thereof
    • Patent number 12,152,244
    • Issue date Nov 26, 2024
    • Ionis Pharmaceuticals, Inc.
    • Michael Oestergaard
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Targeting human satellite II (HSATII)
    • Patent number 12,152,241
    • Issue date Nov 26, 2024
    • The General Hospital Corporation
    • David T. Ting
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Therapeutic compositions for treating pain via multiple targets
    • Patent number 12,152,243
    • Issue date Nov 26, 2024
    • QUELLTX, INC.
    • Graham T. Dempsey
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Antisense oligonucleotides for the treatment of Leber congenital am...
    • Patent number 12,139,711
    • Issue date Nov 12, 2024
    • STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
    • Robert Wilhelmus Johanna Collin
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Methods for targeting pain directed at metabolic pathways
    • Patent number 12,128,062
    • Issue date Oct 29, 2024
    • University of Maryland, Baltimore
    • Ohannes Kevork Melemedjian
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Grant

    Compounds and methods for modulating UBE3A-ATS
    • Patent number 12,129,466
    • Issue date Oct 29, 2024
    • Ionis Pharmaceuticals, Inc.
    • Paymaan Jafar-nejad
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Base editing of ANGPTL3 and methods of using same for treatment of...
    • Patent number 12,115,230
    • Issue date Oct 15, 2024
    • Verve Therapeutics, Inc.
    • Alexandra Chadwick
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Oligonucleotides for modulating SCN9A expression
    • Patent number 12,116,576
    • Issue date Oct 15, 2024
    • HOFFMANN-LA ROCHE INC.
    • Lykke Pedersen
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Selective reduction of allelic variants
    • Patent number 12,110,491
    • Issue date Oct 8, 2024
    • Ionis Pharmaceuticals, Inc.
    • C. Frank Bennett
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Antisense oligonucleotide for targeting progranulin
    • Patent number 12,104,153
    • Issue date Oct 1, 2024
    • HOFFMANN-LA ROCHE INC.
    • Ravi Jagasia
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    PIKFYVE antisense oligonucleotides
    • Patent number 12,104,159
    • Issue date Oct 1, 2024
    • ACURASTEM INCORPORATED
    • Wen-Hsuan Chang
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Compositions for modulating tau expression
    • Patent number 12,091,662
    • Issue date Sep 17, 2024
    • Biogen MA Inc.
    • Holly Kordasiewicz
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Nucleic acid, composition and conjugate comprising the same, and pr...
    • Patent number 12,084,661
    • Issue date Sep 10, 2024
    • Suzhou Ribo Life Science Co., Ltd.
    • Hongyan Zhang
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modified oligonucleotides and methods of use
    • Patent number 12,077,757
    • Issue date Sep 3, 2024
    • JANSSEN PHARMACEUTICA NV
    • Sergei Gryaznov
    • A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
  • Information Patent Grant

    SERPINA1 iRNA compositions and methods of use thereof
    • Patent number 12,071,619
    • Issue date Aug 27, 2024
    • Alnylam Pharmaceuticals, Inc.
    • Alfica Sehgal
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
  • Information Patent Grant

    Modulatory polynucleotides
    • Patent number 12,071,625
    • Issue date Aug 27, 2024
    • VOYAGER THERAPEUTICS, INC.
    • Jinzhao Hou
    • C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents