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last 30 patents
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Patent Grant
Gapmer antisense oligonucleotides targeting SARS-CoV-2 for treating...
Patent number
12,163,132
Issue date
Dec 10, 2024
Children's National Medical Center
Yi-Wen Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides to restore dysferlin protein expression...
Patent number
12,163,129
Issue date
Dec 10, 2024
University of Massachusetts
Robert H. Brown
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for modulating neuronal excitability and m...
Patent number
12,163,130
Issue date
Dec 10, 2024
Icahn School of Medicine at Mount Sinai
Anne Schaefer
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Grant
Oligonucleotides for modulating Tau expression
Patent number
12,163,131
Issue date
Dec 10, 2024
HOFFMANN-LA ROCHE INC.
Peter Hagedorn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modulating the cellular stress response
Patent number
12,157,888
Issue date
Dec 3, 2024
The General Hospital Corporation
Jeannie T. Lee
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of MALAT1 expression
Patent number
12,157,890
Issue date
Dec 3, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Selective antisense compounds and uses thereof
Patent number
12,152,244
Issue date
Nov 26, 2024
Ionis Pharmaceuticals, Inc.
Michael Oestergaard
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Targeting human satellite II (HSATII)
Patent number
12,152,241
Issue date
Nov 26, 2024
The General Hospital Corporation
David T. Ting
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Therapeutic compositions for treating pain via multiple targets
Patent number
12,152,243
Issue date
Nov 26, 2024
QUELLTX, INC.
Graham T. Dempsey
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Antisense oligonucleotides for the treatment of Leber congenital am...
Patent number
12,139,711
Issue date
Nov 12, 2024
STICHTING RADBOUD UNIVERSITAIR MEDISCH CENTRUM
Robert Wilhelmus Johanna Collin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Methods for targeting pain directed at metabolic pathways
Patent number
12,128,062
Issue date
Oct 29, 2024
University of Maryland, Baltimore
Ohannes Kevork Melemedjian
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Compounds and methods for modulating UBE3A-ATS
Patent number
12,129,466
Issue date
Oct 29, 2024
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Base editing of ANGPTL3 and methods of using same for treatment of...
Patent number
12,115,230
Issue date
Oct 15, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Oligonucleotides for modulating SCN9A expression
Patent number
12,116,576
Issue date
Oct 15, 2024
HOFFMANN-LA ROCHE INC.
Lykke Pedersen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Selective reduction of allelic variants
Patent number
12,110,491
Issue date
Oct 8, 2024
Ionis Pharmaceuticals, Inc.
C. Frank Bennett
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Antisense oligonucleotide for targeting progranulin
Patent number
12,104,153
Issue date
Oct 1, 2024
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
PIKFYVE antisense oligonucleotides
Patent number
12,104,159
Issue date
Oct 1, 2024
ACURASTEM INCORPORATED
Wen-Hsuan Chang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions for modulating tau expression
Patent number
12,091,662
Issue date
Sep 17, 2024
Biogen MA Inc.
Holly Kordasiewicz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Nucleic acid, composition and conjugate comprising the same, and pr...
Patent number
12,084,661
Issue date
Sep 10, 2024
Suzhou Ribo Life Science Co., Ltd.
Hongyan Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modified oligonucleotides and methods of use
Patent number
12,077,757
Issue date
Sep 3, 2024
JANSSEN PHARMACEUTICA NV
Sergei Gryaznov
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
SERPINA1 iRNA compositions and methods of use thereof
Patent number
12,071,619
Issue date
Aug 27, 2024
Alnylam Pharmaceuticals, Inc.
Alfica Sehgal
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modulatory polynucleotides
Patent number
12,071,625
Issue date
Aug 27, 2024
VOYAGER THERAPEUTICS, INC.
Jinzhao Hou
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Targeting enhancer RNAs for the treatment of primary brain tumors
Patent number
12,060,557
Issue date
Aug 13, 2024
Brown University
Nikolaos Tapinos
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNAi agents for inhibiting expression of PNPLA3, pharmaceutical com...
Patent number
12,054,718
Issue date
Aug 6, 2024
Arrowhead Pharmaceuticals, Inc.
Anthony Nicholas
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Compositions and methods for ordered and continuous complementary D...
Patent number
12,054,705
Issue date
Aug 6, 2024
The Regents of the University of California
Kathleen Collins
C07 - ORGANIC CHEMISTRY
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Patent Grant
Nucleic acids for inhibiting expression of LPA in a cell
Patent number
12,054,717
Issue date
Aug 6, 2024
Silence Therapeutics GmbH
Sibylle Dames
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Antisense oligonucleotides for the treatment of Stargardt disease
Patent number
12,054,716
Issue date
Aug 6, 2024
Stichting Katholieke Universiteit
Robert Wilhelmus Johanna Collin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Two-tailed self-delivering siRNA
Patent number
12,049,627
Issue date
Jul 30, 2024
University of Massachusetts
Anastasia Khvorova
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Transthyretin (TTR) iRNA compositions and methods of use thereof fo...
Patent number
12,049,628
Issue date
Jul 30, 2024
Alnylam Pharmaceuticals, Inc.
Tracy Zimmermann
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulation of alpha synuclein expression
Patent number
12,043,831
Issue date
Jul 23, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
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Patent Application
RNAi TARGETING KIF1A MISSENSE MUTATIONS FOR TREATMENT OF KIF1A ASSO...
Publication number
20240409936
Publication date
Dec 12, 2024
Ovid Therapeutics Inc.
Noelle Germain
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNAi TARGETING PPP2R5D MISSENSE MUTATIONS FOR TREATMENT OF JORDAN’S...
Publication number
20240409945
Publication date
Dec 12, 2024
Ovid Therapeutics Inc.
Noelle Germain
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PREVENTIVE OR THERAPEUTIC AGENT FOR BENIGN ADULT FAMILIAL MYOCLONIC...
Publication number
20240409926
Publication date
Dec 12, 2024
RIKEN
Haruhisa INOUE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MODIFIED DOUBLE-STRANDED RNA AGENTS
Publication number
20240409942
Publication date
Dec 12, 2024
Alnylam Pharmaceuticals, Inc.
Martin MAIER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN C-III EXPRES...
Publication number
20240401038
Publication date
Dec 5, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING PKK EXPRESSION
Publication number
20240401054
Publication date
Dec 5, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Chemically Modified Guide RNAs for CRISPR/CAS-Mediated Gene Correction
Publication number
20240401034
Publication date
Dec 5, 2024
The Board of Trustees of the Leland Stanford Junior University
Matthew H. Porteus
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compounds and Methods for Reducing ATXN2 Expression
Publication number
20240401039
Publication date
Dec 5, 2024
Ionis Pharmaceuticals, Inc.
Susan M. Freier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
BASE EDITING OF PCSK9 AND METHODS OF USING SAME FOR TREATMENT OF DI...
Publication number
20240390523
Publication date
Nov 28, 2024
Verve Therapeutics, Inc.
Alexandra Chadwick
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
C5a Binding Nucleic Acids
Publication number
20240384275
Publication date
Nov 21, 2024
Aptarion Biotech AG
Kai Hohlig
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Oligonucleotides
Publication number
20240384268
Publication date
Nov 21, 2024
Hudson Institute of Medical Research
Michael Paul Marie Gantier
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPLEMENT COMPONENT iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240376477
Publication date
Nov 14, 2024
Alnylam Pharmaceuticals, Inc.
Anna Borodovsky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Selective Antisense Compounds and Uses Thereof
Publication number
20240368592
Publication date
Nov 7, 2024
Ionis Pharmaceuticals, Inc.
Punit P. Seth
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
GAPMER OLIGONUCLEOTIDES COMPRISING A PHOSPHORODITHIOATE INTERNUCLEO...
Publication number
20240368593
Publication date
Nov 7, 2024
Roche Innovation Center Copenhagen A/S
Konrad Bleicher
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
OLIGONUCLEOTIDES COMPRISING SEGMENTED GAP STRUCTURES
Publication number
20240368602
Publication date
Nov 7, 2024
AUSPERBIO THERAPEUTICS INC.
Guofeng CHENG
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDE THERAPY FOR H3.3 K27M DIFFUSE MIDLINE GLI...
Publication number
20240360450
Publication date
Oct 31, 2024
COLD SPRING HARBOR HARBOR LABORATORY
Adrian Krainer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND MEANS FOR EFFICIENT SKIPPING OF AT LEAST ONE OF THE FOL...
Publication number
20240360452
Publication date
Oct 31, 2024
BioMarin Technologies B.V.
Judith Christina Theodora Van Deutekom
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
Compounds and Methods for Reducing LRRK2 Expression
Publication number
20240360453
Publication date
Oct 31, 2024
Ionis Pharmaceuticals, Inc.
Tracy A. Cole
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
LINKAGE MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF
Publication number
20240360448
Publication date
Oct 31, 2024
Ionis Pharmaceuticals, Inc.
Hans-Joachim Josef Gaus
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE INHIBITORS OF MIR17HG PRE-RNA AS THERAPEUTIC AGENTS IN CA...
Publication number
20240352462
Publication date
Oct 24, 2024
Dana-Farber Cancer Institute, Inc.
Nikhil C. Munshi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR MODULATING APOLIPOPROTEIN (a) EXPRESSION
Publication number
20240352455
Publication date
Oct 24, 2024
Ionis Pharmaceuticals, Inc.
Thazha P. Prakash
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions and methods for ordered and continuous complementary D...
Publication number
20240344050
Publication date
Oct 17, 2024
The Regents of the University of California
Kathleen Collins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Compositions and methods for ordered and continuous complementary D...
Publication number
20240344051
Publication date
Oct 17, 2024
The Regents of the University of California
Kathleen Collins
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT FOR TYROSINE DEGRADATION-ASSOCIATED DISORDERS
Publication number
20240344072
Publication date
Oct 17, 2024
UCL Business LTD
Haiyan Zhou
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
MODULATION OF GENE TRANSCRIPTION USING ANTISENSE OLIGONUCLEOTIDES T...
Publication number
20240336924
Publication date
Oct 10, 2024
CAMP4 THERAPEUTICS CORPORATION
Alfica Sehgal
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
Modification of 3' Terminal Ends of Nucleic Acids by DNA Polymerase...
Publication number
20240336901
Publication date
Oct 10, 2024
Richard T. Pomerantz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
THREOSE NUCLEIC ACID ANTISENSE OLIGONUCLEOTIDES AND METHODS THEREOF
Publication number
20240336920
Publication date
Oct 10, 2024
HOFFMANN-LA ROCHE INC.
Jessica Marine Aurore BASTIEN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
MODULATORS OF ENaC EXPRESSION
Publication number
20240327838
Publication date
Oct 3, 2024
Ionis Pharmaceuticals, Inc.
Jeffrey R. Crosby
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
NUCLEIC ACIDS FOR INHIBITING EXPRESSION OF LPA IN A CELL
Publication number
20240327843
Publication date
Oct 3, 2024
Silence Therapeutics GMBH
Sibylle Dames
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
ANTISENSE OLIGONUCLEOTIDES TARGETING UNC13A
Publication number
20240327845
Publication date
Oct 3, 2024
HOFFMANN-LA ROCHE INC.
Katarzyna Chyzynska
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...