Translation products from oncogenes

Industry

CPC
C07K14/82

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Parent Industries

CCHEMISTRY METALLURGY C07Organic chemistry C07KPEPTIDES C07K14/00Peptides having more than 20 amino acids Gastrins Somatostatins Melanotropins Derivatives thereof

Current Industry

C07K14/82Translation products from oncogenes

Industries

Patents Grantslast 30 patents

Information Patent Grant
Fusion proteins and methods thereof
- Patent number 12,123,005
- Issue date Oct 22, 2024
- The Trustees of Columbia University In the City of New York
- Antonio Iavarone
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 12,071,458
- Issue date Aug 27, 2024
- Immatics Biotechnologies GmbH
- Andrea Mahr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fusions and method for detecting same
- Patent number 12,055,538
- Issue date Aug 6, 2024
- Japanese Foundation for Cancer Research
- Kengo Takeuchi
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
p63 inactivation for the treatment of heart failure
- Patent number 12,031,135
- Issue date Jul 9, 2024
- Baylor College of Medicine
- Vivekkumar B. Patel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Fusion proteins and methods thereof
- Patent number 12,006,503
- Issue date Jun 11, 2024
- The Trustees of Columbia University In the City of New York
- Antonio Iavarone
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Methods of detecting MLH1 methylation
- Patent number 11,993,820
- Issue date May 28, 2024
- Quest Diagnostics Investments LLC
- Kevin Qu
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Fusion proteins and methods thereof
- Patent number 11,920,138
- Issue date Mar 5, 2024
- The Trustees of Columbia University In the City of New York
- Antonio Iavarone
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 11,912,749
- Issue date Feb 27, 2024
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 11,912,748
- Issue date Feb 27, 2024
- Immatics Biotechnologies GmbH
- Andrea Mahr
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-KRAS-G12D T cell receptors
- Patent number 11,897,933
- Issue date Feb 13, 2024
- The United States of America, as represented by the Secretary, Department of...
- Eric Tran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Engineered yeast as a method for bioremediation
- Patent number 11,884,566
- Issue date Jan 30, 2024
- Massachusetts Institute of Technology
- George Le-Le Sun
- C22 - METALLURGY FERROUS OR NON-FERROUS ALLOYS TREATMENT OF ALLOYS OR NON-FER...
Information Patent Grant
T cell-antigen coupler with various construct optimizations
- Patent number 11,878,035
- Issue date Jan 23, 2024
- Triumvira Immunologics USA, Inc.
- Jonathan Lorne Bramson
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Anti-KRAS-G12D T cell receptors
- Patent number 11,840,561
- Issue date Dec 12, 2023
- The United States of America, as represented by the Secretary, Department of...
- Eric Tran
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Translocation and mutant ROS kinase in human non-small cell lung ca...
- Patent number 11,761,005
- Issue date Sep 19, 2023
- Cell Signaling Technology, Inc.
- Ailan Guo
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Therapeutic multi-targeting constructs and uses thereof
- Patent number 11,739,163
- Issue date Aug 29, 2023
- AEBI LTD.
- Ilan Morad
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
HLA-A24 agonist epitopes of MUC1-C oncoprotein and compositions and...
- Patent number 11,732,017
- Issue date Aug 22, 2023
- The USA, as represented by the Secretary, Dept. of Health and Human Services
- Jeffrey Schlom
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Examination method for prediction of effect of treatment of cancer...
- Patent number 11,709,165
- Issue date Jul 25, 2023
- KAWASAKI GAKUEN Educational Foundation
- Mikio Oka
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Listeria-based compositions comprising a peptide minigene expressio...
- Patent number 11,702,664
- Issue date Jul 18, 2023
- Advaxis, Inc.
- Robert Petit
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
CIP2A variant and uses thereof
- Patent number 11,680,092
- Issue date Jun 20, 2023
- Turun Yliopisto
- Eleonora Mäkelä
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Interleukin-2 fusion proteins and uses thereof
- Patent number 11,680,090
- Issue date Jun 20, 2023
- Medicenna Therapeutics, Inc.
- Fahar Merchant
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
T cell receptors recognizing HLA-CW8 restricted mutated KRAS
- Patent number 11,667,692
- Issue date Jun 6, 2023
- The United States of America, as represented by the Secretary, Department of...
- Eric Tran
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Antibodies and processes for preparing the same
- Patent number 11,667,695
- Issue date Jun 6, 2023
- Taiga Biotechnologies, Inc.
- Yosef Refaeli
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptide for treating cancer
- Patent number 11,597,757
- Issue date Mar 7, 2023
- Saint Leo University
- Sergiy I. Borysov
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Methods for generating universal and custom MHC/HLA-compatible hema...
- Patent number 11,564,942
- Issue date Jan 31, 2023
- The General Hospital Corporation
- Michael K. Mansour
- C07 - ORGANIC CHEMISTRY
Information Patent Grant
Compositions and methods for treating lysosomal storage diseases an...
- Patent number 11,548,936
- Issue date Jan 10, 2023
- Children's Medical Center Corporation
- Alessandra Biffi
- G01 - MEASURING TESTING
Information Patent Grant
Coordinating gene expression using RNA destabilizing elements
- Patent number 11,497,774
- Issue date Nov 15, 2022
- Chimera Bioengineering, Inc.
- Benjamin Wang
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Stabilized BCL9 peptides for treatment of aberrant WNT signaling
- Patent number 11,498,947
- Issue date Nov 15, 2022
- WntRx Pharmaceuticals Inc.
- David Zhu
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Grant
Peptides and combination of peptides for use in immunotherapy again...
- Patent number 11,485,765
- Issue date Nov 1, 2022
- Immatics Biotechnologies GmbH
- Andrea Mahr
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
Anti-tumor properties of Dickkopf 3b
- Patent number 11,421,008
- Issue date Aug 23, 2022
- University of Massachusetts
- Jack L. Leonard
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Grant
p63 inactivation for the treatment of heart failure
- Patent number 11,421,229
- Issue date Aug 23, 2022
- Baylor College of Medicine
- Vivekkumar B. Patel
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Patents Applicationslast 30 patents

Information Patent Application
A SHORTENED P63-PROTEIN DOMAIN TO ENHANCE HUMAN CARDIAC REPROGRAMMING
- Publication number 20240342312
- Publication date Oct 17, 2024
- Baylor College of Medicine
- Todd Rosengart
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
FUSION PROTEINS COMPRISING SUPPRESSION OF TUMORIGENICITY 2 OR INTER...
- Publication number 20240327483
- Publication date Oct 3, 2024
- Ziyang Zhong
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS FOR GENERATING PRIMARY IMMUNE CELLS
- Publication number 20240316106
- Publication date Sep 26, 2024
- AstraZeneca AB
- DEEPALI MALHOTRA
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
METHODS OF DETECTING MLH1 METHYLATION
- Publication number 20240301508
- Publication date Sep 12, 2024
- Quest Diagnostics Investments LLC
- Kevin Qu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
COMBINATION USE OF WT1 ANTIGEN PEPTIDE AND IMMUNOMODULATOR
- Publication number 20240293521
- Publication date Sep 5, 2024
- Sumitomo Pharma Co., Ltd.
- Hideo TAKASU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSION PROTEINS AND METHODS THEREOF
- Publication number 20240287530
- Publication date Aug 29, 2024
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Antonio IAVARONE
- G01 - MEASURING TESTING
Information Patent Application
NOVEL TARGETS FOR ENHANCING ANTI-TUMOR IMMUNITY
- Publication number 20240261333
- Publication date Aug 8, 2024
- THE BROAD INSTITUTE, INC.
- Julia Joung
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
FUSION PROTEINS AND METHODS THEREOF
- Publication number 20240247275
- Publication date Jul 25, 2024
- THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
- Antonio IAVARONE
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ARENAVIRUSES AS VECTORS
- Publication number 20240229073
- Publication date Jul 11, 2024
- Hookipa Biotech GmbH
- Timo SCHIPPERS
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
ANTI-KRAS-G12D T CELL RECEPTORS
- Publication number 20240209059
- Publication date Jun 27, 2024
- The United States of America, as represented by the Secretary, Department of...
- Eric Tran
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
GENETICALLY MODIFIED ONCOLYTIC HERPES SIMPLEX VIRUS DELIVERING CHEM...
- Publication number 20240191252
- Publication date Jun 13, 2024
- IMMVIRA BIOPHARMACEUTICALS CO., LIMITED
- Xiaoqing CHEN
- C07 - ORGANIC CHEMISTRY
Information Patent Application
HLA-RESTRICTED EPITOPES ENCODED BY SOMATICALLY MUTATED GENES
- Publication number 20240166751
- Publication date May 23, 2024
- The Johns Hopkins University
- Bert Vogelstein
- C07 - ORGANIC CHEMISTRY
Information Patent Application
COMPOSITIONS AND METHODS FOR ENHANCING ADOPTIVE T CELL THERAPEUTICS
- Publication number 20240165161
- Publication date May 23, 2024
- The Regents of the University of California
- Kole ROYBAL
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
MODULATORS OF MYC, METHODS OF USING THE SAME, AND METHODS OF IDENIF...
- Publication number 20240156957
- Publication date May 16, 2024
- HTYR ACQUISITION LLC
- Yosef Refaeli
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
INTERLEUKIN-2 FUSION PROTEINS AND USES THEREOF
- Publication number 20240067689
- Publication date Feb 29, 2024
- Medicenna Therapeutics, Inc.
- Fahar Merchant
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
TREATMENT OF CANCER ASSOCIATED WITH VARIANT NOVEL OPEN READING FRAMES
- Publication number 20240060070
- Publication date Feb 22, 2024
- CAMBRIDGE ENTERPRISE LIMITED
- Sudhakaran PRABAKARAN
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
THERAPEUTIC MULTI-TARGETING CONSTRUCTS AND USES THEREOF
- Publication number 20240002547
- Publication date Jan 4, 2024
- AEBI LTD.
- llan MORAD
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
RAS MUTANT EPITOPE PEPTIDE AND T CELL RECEPTOR RECOGNIZING RAS MUTANT
- Publication number 20240000834
- Publication date Jan 4, 2024
- Shanghai GenBase Biotechnology Co., Ltd.
- Nan Mou
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
Nucleic Acid Molecule Binding to YB-1 Protein
- Publication number 20240002855
- Publication date Jan 4, 2024
- Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences
- JingYi Hui
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T CELL RECEPTORS RECOGNIZING HLA-CW8 RESTRICTED MUTATED KRAS
- Publication number 20230406904
- Publication date Dec 21, 2023
- The United States of America, as represented by the Secretary, Department of...
- Eric Tran
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
LISTERIA-BASED COMPOSITIONS COMPRISING A PEPTIDE MINIGENE EXPRESSIO...
- Publication number 20230357781
- Publication date Nov 9, 2023
- Advaxis, Inc.
- Robert Petit
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PROTEASE CLEAVABLE BISPECIFIC ANTIBODIES AND USES THEREOF
- Publication number 20230357410
- Publication date Nov 9, 2023
- Zhejiang Shimai Pharmaceutical Co.,Ltd.
- Weizao Chen
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
DESTABILIZED ARE 3'UTRs AS THERAPEUTICS FOR CANCER
- Publication number 20230331818
- Publication date Oct 19, 2023
- Research Foundation of the City University of New York
- Olorunseun O. Ogunwobi
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
HLA-A24 AGONIST EPITOPES OF MUC1-C ONCOPROTEIN AND COMPOSITIONS AND...
- Publication number 20230331797
- Publication date Oct 19, 2023
- The USA, as represented by the Secretary, Dept. of Health & Human Services
- Jeffrey Schlom
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
METHODS FOR CULTURING CELLS EXPRESSING C-JUN
- Publication number 20230313138
- Publication date Oct 5, 2023
- Lyell Immunopharma, Inc.
- Suman Kumar VODNALA
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
T CELLS AND CHIMERIC STIMULATING RECEPTORS AND USES THEREOF
- Publication number 20230293687
- Publication date Sep 21, 2023
- Eureka Therapeutics, Inc.
- Cheng Liu
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
STABILIZED BCL9 PEPTIDES FOR TREATMENT OF ABERRANT WNT SIGNALING
- Publication number 20230265138
- Publication date Aug 24, 2023
- WntRx Pharmaceuticals Inc.
- David ZHU
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
KIF5B-RET FUSION MOLECULES AND USES THEREOF
- Publication number 20230241065
- Publication date Aug 3, 2023
- FOUNDATION MEDICINE, INC.
- Sean R. Downing
- A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information Patent Application
NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY...
- Publication number 20230227517
- Publication date Jul 20, 2023
- Immatics Biotechnologies GmbH
- Andrea MAHR
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information Patent Application
PROTEIN SECRETORY FACTOR WITH HIGH SECRETORY EFFICIENCY AND AN EXPR...
- Publication number 20230212236
- Publication date Jul 6, 2023
- LG CHEM, LTD.
- Seung Hae KIM
- C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...

Translation products from oncogenes

Industry

Parent Industries

Current Industry

Patents Grantslast 30 patents

Fusion proteins and methods thereof

Peptides and combination of peptides for use in immunotherapy again...

Fusions and method for detecting same

p63 inactivation for the treatment of heart failure

Fusion proteins and methods thereof

Methods of detecting MLH1 methylation

Fusion proteins and methods thereof

Peptides and combination of peptides for use in immunotherapy again...

Peptides and combination of peptides for use in immunotherapy again...

Anti-KRAS-G12D T cell receptors

Engineered yeast as a method for bioremediation

T cell-antigen coupler with various construct optimizations

Anti-KRAS-G12D T cell receptors

Translocation and mutant ROS kinase in human non-small cell lung ca...

Therapeutic multi-targeting constructs and uses thereof

HLA-A24 agonist epitopes of MUC1-C oncoprotein and compositions and...

Examination method for prediction of effect of treatment of cancer...

Listeria-based compositions comprising a peptide minigene expressio...

CIP2A variant and uses thereof

Interleukin-2 fusion proteins and uses thereof

T cell receptors recognizing HLA-CW8 restricted mutated KRAS

Antibodies and processes for preparing the same

Peptide for treating cancer

Methods for generating universal and custom MHC/HLA-compatible hema...

Compositions and methods for treating lysosomal storage diseases an...

Coordinating gene expression using RNA destabilizing elements

Stabilized BCL9 peptides for treatment of aberrant WNT signaling

Peptides and combination of peptides for use in immunotherapy again...

Anti-tumor properties of Dickkopf 3b

p63 inactivation for the treatment of heart failure

Patents Applicationslast 30 patents

A SHORTENED P63-PROTEIN DOMAIN TO ENHANCE HUMAN CARDIAC REPROGRAMMING

FUSION PROTEINS COMPRISING SUPPRESSION OF TUMORIGENICITY 2 OR INTER...

METHODS FOR GENERATING PRIMARY IMMUNE CELLS

METHODS OF DETECTING MLH1 METHYLATION

COMBINATION USE OF WT1 ANTIGEN PEPTIDE AND IMMUNOMODULATOR

FUSION PROTEINS AND METHODS THEREOF

NOVEL TARGETS FOR ENHANCING ANTI-TUMOR IMMUNITY

FUSION PROTEINS AND METHODS THEREOF

ARENAVIRUSES AS VECTORS

ANTI-KRAS-G12D T CELL RECEPTORS

GENETICALLY MODIFIED ONCOLYTIC HERPES SIMPLEX VIRUS DELIVERING CHEM...

HLA-RESTRICTED EPITOPES ENCODED BY SOMATICALLY MUTATED GENES

COMPOSITIONS AND METHODS FOR ENHANCING ADOPTIVE T CELL THERAPEUTICS

MODULATORS OF MYC, METHODS OF USING THE SAME, AND METHODS OF IDENIF...

INTERLEUKIN-2 FUSION PROTEINS AND USES THEREOF

TREATMENT OF CANCER ASSOCIATED WITH VARIANT NOVEL OPEN READING FRAMES

THERAPEUTIC MULTI-TARGETING CONSTRUCTS AND USES THEREOF

RAS MUTANT EPITOPE PEPTIDE AND T CELL RECEPTOR RECOGNIZING RAS MUTANT

Nucleic Acid Molecule Binding to YB-1 Protein

T CELL RECEPTORS RECOGNIZING HLA-CW8 RESTRICTED MUTATED KRAS

LISTERIA-BASED COMPOSITIONS COMPRISING A PEPTIDE MINIGENE EXPRESSIO...

PROTEASE CLEAVABLE BISPECIFIC ANTIBODIES AND USES THEREOF

DESTABILIZED ARE 3'UTRs AS THERAPEUTICS FOR CANCER

HLA-A24 AGONIST EPITOPES OF MUC1-C ONCOPROTEIN AND COMPOSITIONS AND...

METHODS FOR CULTURING CELLS EXPRESSING C-JUN

T CELLS AND CHIMERIC STIMULATING RECEPTORS AND USES THEREOF

STABILIZED BCL9 PEPTIDES FOR TREATMENT OF ABERRANT WNT SIGNALING

KIF5B-RET FUSION MOLECULES AND USES THEREOF

NOVEL PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY...

PROTEIN SECRETORY FACTOR WITH HIGH SECRETORY EFFICIENCY AND AN EXPR...