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Tumor necrosis factor [TNF]
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CHEMISTRY METALLURGY
C07
Organic chemistry
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PEPTIDES
C07K14/00
Peptides having more than 20 amino acids Gastrins Somatostatins Melanotropins Derivatives thereof
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C07K14/525
Tumor necrosis factor [TNF]
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Patents Grants
last 30 patents
Information
Patent Grant
Single-chain TNF Receptor 2 agonist fusion proteins
Patent number
12,365,712
Issue date
Jul 22, 2025
RELINIA, INC.
David C Foster
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Protein conjugates
Patent number
12,344,645
Issue date
Jul 1, 2025
Polaris Group
Robert J. Almassy
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antibody-TNF α fusion protein and its preparation and applications
Patent number
12,344,646
Issue date
Jul 1, 2025
Zeling Cai
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Oncolytic virus platform to treat cancers with myxoma virus
Patent number
12,331,079
Issue date
Jun 17, 2025
Arizona Board of Regents on behalf of Arizona State University
Douglas Grant McFadden
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods for reducing post-operative cognitive dysfunction (POCD)
Patent number
12,325,744
Issue date
Jun 10, 2025
THE KENNEDY TRUST FOR RHEUMATOLOGY RESEARCH
Mervyn Maze
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cancer prevention and therapy by inhibiting soluble tumor necrosis...
Patent number
12,303,558
Issue date
May 20, 2025
University of Pittsburgh of the Commonwealth System of Higher Education
Nikola L. Vujanovic
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of treating cancer with TNF expressing myxoma virus
Patent number
12,257,278
Issue date
Mar 25, 2025
Arizona Board of Regents on behalf of Arizona State University
Douglas Grant McFadden
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods of prognosis and treatment
Patent number
12,228,579
Issue date
Feb 18, 2025
MeMed Diagnostics Ltd.
Eran Eden
G01 - MEASURING TESTING
Information
Patent Grant
Cytokine fusion proteins
Patent number
12,226,481
Issue date
Feb 18, 2025
Beijing Percans Oncology Co., Ltd.
Yiyou Chen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Targeted modified TNF family members
Patent number
12,227,550
Issue date
Feb 18, 2025
VIB VZW
Jan Tavernier
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Antigen binding molecules comprising a trimeric TNF family ligand a...
Patent number
12,202,870
Issue date
Jan 21, 2025
HOFFMANN-LA ROCHE INC.
Maria Amann
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
ATP-dependent agonists of immune cells function as anticancer agents
Patent number
12,180,297
Issue date
Dec 31, 2024
Crosslink Therapeutics Inc.
Rodolfo J. Chaparro
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
TNFR2 agonists with improved stability
Patent number
12,173,046
Issue date
Dec 24, 2024
Universitat Stuttgart
Roman Fischer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods of administering mesenchymal stem cells activated by cytoki...
Patent number
12,156,889
Issue date
Dec 3, 2024
Rutgers, The State University of New Jersey
Yufang Shi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Dendritic cell generator
Patent number
12,157,901
Issue date
Dec 3, 2024
Northeastern University
Shashi K. Murthy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Mutant human estrogen receptor-α and methods of use thereof
Patent number
12,135,332
Issue date
Nov 5, 2024
Case Western Reserve University
Sichun Yang
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Fusion protein comprising an antigen binding domain and a cytokine...
Patent number
12,122,813
Issue date
Oct 22, 2024
CTCELLS, INC.
Kka Bi Son
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Methods of making and using extracellular domain-based chimeric pro...
Patent number
12,071,465
Issue date
Aug 27, 2024
Shattuck Labs, Inc.
Taylor Schreiber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Tumor necrosis factor receptor (TNFR) binding protein complex with...
Patent number
12,065,472
Issue date
Aug 20, 2024
Universitat Stuttgart
Roman Fischer
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Methods of use of anti-TNFα antibodies
Patent number
12,055,549
Issue date
Aug 6, 2024
UCB Biopharma SRL
James Philip O'Connell
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Protein signatures for distinguishing between bacterial and viral i...
Patent number
12,044,681
Issue date
Jul 23, 2024
MeMed Diagnostics Ltd.
Eran Eden
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
MHC class II T-cell modulatory multimeric polypeptides for treating...
Patent number
12,029,782
Issue date
Jul 9, 2024
Cue Biopharma, Inc.
Ronald D. Seidel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Enhanced depletion of targeted cells with CD47 blockade and an immu...
Patent number
12,030,944
Issue date
Jul 9, 2024
The Board of Trustees of the Leland Stanford Junior University
Peter Schnorr
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Stable liquid formula comprising anti-TNFa antibody, acetate buffer...
Patent number
11,986,523
Issue date
May 21, 2024
Celltrion Inc.
Joon Won Lee
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
T cell-antigen coupler with Y182T mutation and methods of uses thereof
Patent number
11,970,545
Issue date
Apr 30, 2024
McMaster University
Christopher W. Helsen
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Serpin fusion polypeptides and methods of use thereof
Patent number
11,965,017
Issue date
Apr 23, 2024
Inhibrx, Inc.
Brendan P. Eckelman
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Modification of immune cells for reducing toxicity and uses thereof...
Patent number
11,965,176
Issue date
Apr 23, 2024
HUNAN SIWEIKANG THERAPEUTICS CO. LTD
Biliang Hu
C07 - ORGANIC CHEMISTRY
Information
Patent Grant
Modified TNF as a capture ligand
Patent number
11,957,825
Issue date
Apr 16, 2024
IMMUNICOM INC.
Michael Matho
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
Information
Patent Grant
Methods for inducing an immune response by administering activated...
Patent number
11,872,250
Issue date
Jan 16, 2024
Rutgers, The State University of New Jersey
Yufang Shi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Arginine-free TNFR:FC-fusion polypeptide compositions
Patent number
11,834,491
Issue date
Dec 5, 2023
Biogen MA Inc.
Kevin Maloney
C07 - ORGANIC CHEMISTRY
Patents Applications
last 30 patents
Information
Patent Application
CHIMERIC ANTIGEN RECEPTOR MODIFIED REGULATORY T CELLS FOR TREATING...
Publication number
20250235478
Publication date
Jul 24, 2025
MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
Leonardo M.R. FERREIRA
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
HETERODIMERIC HUMAN IgG1 POLYPEPTIDES WITH ISOELECTRIC POINT MODIFI...
Publication number
20250230262
Publication date
Jul 17, 2025
Xencor, Inc.
Gregory L. Moore
C07 - ORGANIC CHEMISTRY
Information
Patent Application
DOMINANT-NEGATIVE TUMOR NECROSIS FACTOR ALPHA ADENO-ASSOCIATED VIRU...
Publication number
20250213727
Publication date
Jul 3, 2025
Regenxbio Inc.
Danielle SLITER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ATP-Dependent Agonists of Immune Cells Function as Anticancer Agents
Publication number
20250197521
Publication date
Jun 19, 2025
Crosslink Therapeutics Inc.
Rodolfo J. CHAPARRO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
IL-2 AND TL1A FUSION PROTEINS AND METHODS OF USE THEREOF
Publication number
20250154216
Publication date
May 15, 2025
University of Miami
Robert B. LEVY
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TNF-ALPHA VARIANT FUSION MOLECULES
Publication number
20250122256
Publication date
Apr 17, 2025
TRex Bio, Inc.
Robin Allene Aglietti
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF ONCOLOGY-RELATED PRO...
Publication number
20250074962
Publication date
Mar 6, 2025
ModernaTX, Inc.
Antonin DE FOUGEROLLES
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Dendritic Cell Generator
Publication number
20250051707
Publication date
Feb 13, 2025
Northeastern University
Shashi K. Murthy
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
RNA CONSTRUCT
Publication number
20250051798
Publication date
Feb 13, 2025
Imperial College Innovations Limited
Paul McKay
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CYTOKINE COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250034221
Publication date
Jan 30, 2025
Zahav Bioscience LLC
Giulio Franco Paciotti
B82 - NANO-TECHNOLOGY
Information
Patent Application
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF BIOLOGICS AND PROTEI...
Publication number
20250018062
Publication date
Jan 16, 2025
Moderna TX, Inc.
Antonin DE FOUGEROLLES
Y02 - TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMA...
Information
Patent Application
MECHANISM OF ACTION
Publication number
20250012807
Publication date
Jan 9, 2025
UCB Biopharma SRL
James Philip O'CONNELL
G01 - MEASURING TESTING
Information
Patent Application
SERPIN FUSION POLYPEPTIDES AND METHODS OF USE THEREOF
Publication number
20250011394
Publication date
Jan 9, 2025
Sanofi AATD Inc.
Brendan P. ECKELMAN
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
PROTEIN SIGNATURES FOR DISTINGUISHING BETWEEN BACTERIAL AND VIRAL I...
Publication number
20240418716
Publication date
Dec 19, 2024
MeMed Diagnostics Ltd.
Eran EDEN
G01 - MEASURING TESTING
Information
Patent Application
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF SECRETED PROTEINS
Publication number
20240409597
Publication date
Dec 12, 2024
ModernaTX, Inc.
Antonin DE FOUGEROLLES
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
TRIMERIC ACTIVATABLE CYTOKINE CONSTRUCTS AND RELATED COMPOSITIONS A...
Publication number
20240398920
Publication date
Dec 5, 2024
CytomX Therapeutics, Inc.
Erwan LE SCOLAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ENHANCED DEPLETION OF TARGETED CELLS WITH CD47 BLOCKADE AND AN IMMU...
Publication number
20240400688
Publication date
Dec 5, 2024
The Board of Trustees of the Leland Stanford Junior University
Peter Schnorr
C07 - ORGANIC CHEMISTRY
Information
Patent Application
SPLIT HUMAN IFN-GAMMA AND TNF-ALPHA CONSTRUCTS AND USES THEREOF
Publication number
20240400633
Publication date
Dec 5, 2024
Orionis Biosciences, Inc.
Nikolai KLEY
C07 - ORGANIC CHEMISTRY
Information
Patent Application
METHODS OF MAKING AND USING EXTRACELLULAR DOMAIN-BASED CHIMERIC PRO...
Publication number
20240368242
Publication date
Nov 7, 2024
Shattuck Labs, Inc.
Taylor Schreiber
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
STABLE LIQUID FORMULA
Publication number
20240358827
Publication date
Oct 31, 2024
CELLTRION INC.
Joon Won LEE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
EARLY DETECTION OF INNATE IMMUNE DYSFUNCTION AND TREATMENT OF CONDI...
Publication number
20240345090
Publication date
Oct 17, 2024
University of Florida Research Foundation, Incorporated
Malú Mariadelourdes Gámez TANSEY
G01 - MEASURING TESTING
Information
Patent Application
MACROPHAGE SPECIFIC ENGAGER COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20240327482
Publication date
Oct 3, 2024
Myeloid Therapeutics, Inc.
Daniel Getts
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF PROTEINS ASSOCIATED...
Publication number
20240327476
Publication date
Oct 3, 2024
ModernaTX, Inc.
Antonin DE FOUGEROLLES
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
MHC CLASS II T-CELL MODULATORY MULTIMERIC POLYPEPTIDES FOR TREATING...
Publication number
20240299515
Publication date
Sep 12, 2024
Cue Biopharma, Inc.
Ronald D. Seidel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS FOR INDUCING AN IMMUNE RESPONSE BY ADMINISTERING ACTIVATED...
Publication number
20240269188
Publication date
Aug 15, 2024
Rutgers, The State University of New Jersey
Yufang Shi
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Application
ATP-Dependent Agonists of Immune Cells Function as Anticancer Agents
Publication number
20240254254
Publication date
Aug 1, 2024
Crosslink Therapeutics Inc.
Rodolfo J. CHAPARRO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
MODIFIED TNF AS A CAPTURE LIGAND
Publication number
20240252732
Publication date
Aug 1, 2024
Immunicom, Inc.
Michael MATHO
C07 - ORGANIC CHEMISTRY
Information
Patent Application
A SUPER-TRAIL MOLECULE COMPRISING TWO TRAIL TRIMERS
Publication number
20240254193
Publication date
Aug 1, 2024
Bejing Anxinhuaide Biotech, Co., Ltd
Xinguo QIAN
C07 - ORGANIC CHEMISTRY
Information
Patent Application
ANTIBODIES TARGETING BAFF-R AND USE THEREOF
Publication number
20240228645
Publication date
Jul 11, 2024
Dragonfly Therapeutics, Inc.
Benjamin FISCHER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antigen-Presenting Polypeptides with Chemical Conjugation Sites and...
Publication number
20240197846
Publication date
Jun 20, 2024
Cue Biopharma, Inc.
Ronald D. SEIDEL
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...