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wherein the non-active part clearly interacts with the delivered nuclic acid
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Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases Gene therapy
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wherein the non-active part clearly interacts with the delivered nuclic acid
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Heterologous targeting peptide grafted AAVs
Patent number
12,291,719
Issue date
May 6, 2025
UNIVERSITY OF MASSACHUSETTS
Miguel Sena Esteves
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Recombinant adenoviruses carrying transgenes
Patent number
12,280,123
Issue date
Apr 22, 2025
EpicentRx, Inc.
Christopher Larson
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High-transducing HSV vectors
Patent number
12,275,949
Issue date
Apr 15, 2025
Periphagen, Inc.
David M. Krisky
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Composition and methods for treatment of ornithine transcarbamylase...
Patent number
12,268,754
Issue date
Apr 8, 2025
Translate Bio, Inc.
Kim Askew
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Optimized mRNA encoding CAS9 for use in LNPs
Patent number
12,263,227
Issue date
Apr 1, 2025
CRISPR THERAPEUTICS AG
Christopher J. Cheng
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Collagen-mimetic peptide mediated delivery of nucleic acid carriers...
Patent number
12,171,809
Issue date
Dec 24, 2024
University of Delaware
Kristi Kiick
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Genetically modified bacteria and methods for genetic modification...
Patent number
12,049,633
Issue date
Jul 30, 2024
Crown Laboratories, Inc.
Thomas Hitchcock
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Tunable endogenous protein degradation with heterobifunctional comp...
Patent number
12,023,385
Issue date
Jul 2, 2024
Dana-Farber Cancer Institute, Inc.
Dennis Buckley
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Compositions and methods for delivery of nucleic acids to cells
Patent number
12,005,121
Issue date
Jun 11, 2024
Yale University
Elias Quijano
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Messenger RNA therapy for treatment of articular disease
Patent number
11,998,601
Issue date
Jun 4, 2024
Translate Bio, Inc.
Frank DeRosa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Compositions and methods for treating Huntington's disease
Patent number
11,951,121
Issue date
Apr 9, 2024
VOYAGER THERAPEUTICS, INC.
Dinah Wen-Yee Sah
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Compositions and methods for treatment of peroxisome proliferator-a...
Patent number
11,896,678
Issue date
Feb 13, 2024
Dana-Farber Cancer Institute, Inc.
Jonathan Goldstein
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Compositions and methods for delivery of nucleic acids to cells
Patent number
11,872,286
Issue date
Jan 16, 2024
Yale University
Elias Quijano
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Compositions and methods for delivery of nucleic acids to cells
Patent number
11,850,284
Issue date
Dec 26, 2023
Yale University
Elias Quijano
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Treatments for retinal disease
Patent number
11,766,487
Issue date
Sep 26, 2023
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
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High-transducing HSV vectors
Patent number
11,753,653
Issue date
Sep 12, 2023
Periphagen, Inc.
David M. Krisky
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Method and composition for treating neuropathic pain
Patent number
11,707,535
Issue date
Jul 25, 2023
The Regents of the University of California
Martin Marsala
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Rational polyploid adeno-associated virus vectors for the treatment...
Patent number
11,702,676
Issue date
Jul 18, 2023
The University of North Carolina at Chapel Hill
Chengwen Li
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Treatment of monogenetic disorders
Patent number
11,634,472
Issue date
Apr 25, 2023
ZENTRUM FÜR FORSCHUNGSFÖRDERUNG IN DER PÄDIATRIE GMBH
Helmut Hanenberg
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Methods for modulating RNA splicing
Patent number
11,602,567
Issue date
Mar 14, 2023
PTC Therapeutics, Inc.
Nikolai Naryshkin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Treatments for retinal disease
Patent number
11,576,983
Issue date
Feb 14, 2023
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Polynucleotides encoding interleukin-12 (IL12) and uses thereof
Patent number
11,571,463
Issue date
Feb 7, 2023
ModernaTX, Inc.
Joshua Frederick
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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RNA formulation for immunotherapy
Patent number
11,559,587
Issue date
Jan 24, 2023
TRON—Translationale Onkologie an der Universitatsmedizin der Johannes Gutenbe...
Ugur Sahin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Semi-synthetic tissue constructs for tissue regeneration
Patent number
11,559,606
Issue date
Jan 24, 2023
The Penn State Research Foundation
Yong Wang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Expression constructs, fusogenic lipid-based nanoparticles and meth...
Patent number
11,525,146
Issue date
Dec 13, 2022
OISIN BIOTECHNOLOGIES, INC.
Matthew Rein Scholz
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Non-viral gene delivery agent comprising lipopeptide (LP) compounds
Patent number
11,446,393
Issue date
Sep 20, 2022
Monash University
Colin William Pouton
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Biodegradable lipids for delivery of nucleic acids
Patent number
11,433,144
Issue date
Sep 6, 2022
Translate Bio, Inc.
Frank Derosa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Vectors comprising stuffer/filler polynucleotide sequences and meth...
Patent number
11,427,835
Issue date
Aug 30, 2022
The Children's Hospital of Philadelphia
J. Fraser Wright
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Adeno-associated virus variant capsids and methods of use thereof
Patent number
11,419,949
Issue date
Aug 23, 2022
4D MOLECULAR THERAPEUTICS INC.
David H. Kirn
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Aminoalcohol lipidoids and uses thereof
Patent number
11,414,393
Issue date
Aug 16, 2022
Massachusetts Institute of Technology
Kerry Peter Mahon
B01 - PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
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last 30 patents
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RNA CONTAINING COMPOSITION FOR TREATMENT OF TUMOR DISEASES
Publication number
20250213724
Publication date
Jul 3, 2025
CureVac SE
Mariola FOTIN-MLECZEK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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COMPOSITION AND METHODS FOR TREATMENT OF ORNITHINE TRANSCARBAMYLASE...
Publication number
20250152739
Publication date
May 15, 2025
Translate Bio, Inc.
Kim Askew
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
SCAFFOLDS FOR MODIFYING IMMUNE CELLS AND THE USES THEREOF
Publication number
20250127929
Publication date
Apr 24, 2025
President and Fellows of Harvard College
David T. Scadden
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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RECOMBINANT AAV CAPSID PROTEINS
Publication number
20250115643
Publication date
Apr 10, 2025
VectorY B.V.
Barbara Sanders
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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METHODS AND COMPOSITIONS FOR SYNTHETIC BIOMARKERS
Publication number
20250064973
Publication date
Feb 27, 2025
EARLI Inc.
David SUHY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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TRANSGENIC EXPRESSION CASSETTE FOR TREATING MUSCULAR DYSTROPHY
Publication number
20250066437
Publication date
Feb 27, 2025
SHANGHAI MYGT BIOPHARMACEUTICAL LLC
Mengdi YAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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CELL DELIVERY COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250025576
Publication date
Jan 23, 2025
The Regents of the University of California
Ross C. Wilson
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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GENETICALLY MODIFIED BACTERIA AND METHODS FOR GENETIC MODIFICATION...
Publication number
20250002924
Publication date
Jan 2, 2025
CROWN LABORATORIES, INC.
Thomas HITCHCOCK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
COMPOSITIONS AND METHODS FOR TREATING HUNTINGTON'S DISEASE
Publication number
20240415868
Publication date
Dec 19, 2024
VOYAGER THERAPEUTICS, INC.
Dinah Wen-Yee Sah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MESSENGER RNA THERAPY FOR TREATMENT OF ARTICULAR DISEASE
Publication number
20240415958
Publication date
Dec 19, 2024
Translate Bio, Inc.
Frank DeRosa
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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NUCLEIC ACID CONSTRUCTS, VIRAL VECTORS AND VIRAL PARTICLES
Publication number
20240417434
Publication date
Dec 19, 2024
UCB Biopharma SRL
Natalia RODRIGUEZ ALVAREZ
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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IN VIVO DELIVERY OF OLIGONUCLEOTIDES
Publication number
20240401040
Publication date
Dec 5, 2024
ONCOIMMUNIN, INC.
Beverly PACKARD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF
Publication number
20240366518
Publication date
Nov 7, 2024
ElevateBio Technologies, Inc.
Jessica Deterling
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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MINERAL-COATED SUBSTRATES FOR STABILIZATION OF RNA-BASED THERAPEUTI...
Publication number
20240325596
Publication date
Oct 3, 2024
Wisconsin Alumni Research Foundation
Joshua CHOE
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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CAPSID VARIANTS AND METHODS OF USING THE SAME
Publication number
20240294578
Publication date
Sep 5, 2024
DYNO THERAPEUTICS, INC.
Sylvain Lapan
C07 - ORGANIC CHEMISTRY
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DIFFERENTIAL CXCR4 EXPRESSION ON HEMATOPOIETIC PROGENITOR CELLS VER...
Publication number
20240293466
Publication date
Sep 5, 2024
Children's Hospital Medical Center
Punam Malik
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Application
COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS
Publication number
20240285775
Publication date
Aug 29, 2024
Yale University
Elias QUIJANO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Application
COMPOSITIONS AND METHODS FOR DELIVERY OF NUCLEIC ACIDS TO CELLS
Publication number
20240285774
Publication date
Aug 29, 2024
Yale University
Elias QUIJANO
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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PROMOTER-ENHANCER SEQUENCES OF THE HUMAN TROPONIN T GENE FOR SELECT...
Publication number
20240270804
Publication date
Aug 15, 2024
Cardiac RSK3 Inhibitors, LLC
Michael S. KAPILOFF
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Application
Compositions and Methods for Treating Skeletal Muscle Disease
Publication number
20240216530
Publication date
Jul 4, 2024
Yale University
Elias Quijano
C07 - ORGANIC CHEMISTRY
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Patent Application
COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS...
Publication number
20240200118
Publication date
Jun 20, 2024
Renagade Therapeutics Management Inc.
Inna SHCHERBAKOVA
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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VARIANT-SPECIFIC EXOGENOUS DNA TEMPLATE-FREE CORRECTION OF PATHOGEN...
Publication number
20240197914
Publication date
Jun 20, 2024
Oklahoma Medical Research Foundation
Wan Hee Yoon
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FIBRIL PEPTIDES
Publication number
20240190918
Publication date
Jun 13, 2024
UNIVERSITAT ULM
Jan Münch
C07 - ORGANIC CHEMISTRY
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PRODUCTION OF CIRCULAR POLYRIBONUCLEOTIDES IN A EUKARYOTIC SYSTEM
Publication number
20240181079
Publication date
Jun 6, 2024
Flagship Pioneering Innovations VII, LLC
Barry Andrew Martin
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF
Publication number
20240173267
Publication date
May 30, 2024
ONCORUS, INC.
Jessica Deterling
C07 - ORGANIC CHEMISTRY
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HIGH-TRANSDUCING HSV VECTORS
Publication number
20240158809
Publication date
May 16, 2024
PeriphaGen, Inc.
David M. Krisky
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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ADENO-ASSOCIATED VIRUS VARIANT CAPSIDS WITH IMPROVED RETINAL TRANSD...
Publication number
20240066145
Publication date
Feb 29, 2024
4D MOLECULAR THERAPEUTICS INC.
David H. KIRN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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USE OF CYP4V2 AND RDCVF IN THE MANUFACTURE OF MEDICAMENT
Publication number
20240024433
Publication date
Jan 25, 2024
CHIGENOVO CO., LTD.
Liping Yang
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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POLYNUCLEOTIDES ENCODING INTERLEUKIN-12 (IL12) AND USES THEREOF
Publication number
20240024422
Publication date
Jan 25, 2024
ModernaTX, Inc.
Joshua FREDERICK
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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RATIONAL POLYPLOID ADENO-ASSOCIATED VIRUS VECTORS FOR THE TREATMENT...
Publication number
20230392167
Publication date
Dec 7, 2023
The University of North Carolina at Chapel Hill
Chengwen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...