DiMaio, J. et al., "Bifunctional Thrombin Inhibitors Based on the Sequence of Hirudin," J. Biol. Chem., vol. 265, No. 35, pp. 21698-21703 (1990). |
Johnson, P. H. et al., "Biochemistry and Genetic Engineering of Hirudin," Seminars in Thrombosis and Hemostasis, vol. 15, No. 3, 1989. |
Lazar, J. B. et al., "Hirudin:Amino-Terminal Residues Play a Major Role in the Interaction with Thrombin," J. Biol. Chem., vol. 266, No. 2 pp. 685-688 (1991). |
Maraganore, J. M. et al., "Design and Characterization of Hirulogs:A Novel Class of Bivalent Peptide," Abstract presented symposium Biomedical Horizons of the Leech, Oct. 24-28, 1990. |
Maraganore, J. M., et al., "Design and Characterization of Hirulogs:A Novel Class of Bivalent Peptide Inhibitors of Thrombin," Biochemistry 29, pp. 7095-7101 (1990). |
Markwardt, F. "Development of Hirudin as an Antithrombotic Agent," Seminars in Thrombosis and Hemostatis, vol. 15, No. 3, pp. 269-282 (1989). |
Rydel, T. J. et al., "The Structure of a Complex of Recombinant Hirudin and Human Antithrombin," Science, 249, pp. 277-280 (1990). |
Krstenansky, J.L. et al., J. Med. Chem. 30, pp. 1688 to 1691 (1987). |