Zlotnik and Yoshie Immunity 2000;12:121-127.* |
Mackay Nature Immunol. 2001;2:95-101.* |
Chuntharapai, et al., “Generation of Monoclonal Antibodies to Chemokine Receptors”, Methods in Enzymology 288: 15-27 (Sep. 1997). |
Dean, M., et al., “Genetic Restriction of HIV-1 Infection and Progression to AIDS by a Deletion Allele of the CKR5 Structural Gene”, Science, 273:1856-1862 (1996). |
Liu, R., et al., “Homozygous Defect in HIV-1 Coreceptor Accounts for Resistance of Some Multiply-Exposed Individuals to HIV-1 Infection”, Cell, 86:367-377 (1996). |
Bates, P., “Chemokine Receptors and HIV-1: An Attractive Pair?”, Cell, 86:1-3 (1996). |
Choe, H., et al., “The β-Chemiokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates”, Cell, 85:1135-1148 (1996). |
Samson, M., et al., “Molecular Cloning and Functional Expression of a New Human CC-Chemokine Receptor Gene”, Biochemistry, 35:3362-3367 (1996). |
Raport, C.J., et al., “Molecular Cloning and Functional Characterization of a Novel Human CC Chemokine Receptor (CCR5) for RANTES, MIP-1β, and MIP-1α”, Jour. of Biol. Chem., 271(29): 17161-17166 (1996). |
Boring, L., et al., “Molecular Cloning and Functional Expression of Murine JE (Monocyte Chemoattractant Protein 1) and Murine Macrophage Inflammatory Protein 1α Receptors”, Jour. of Biol. Chem., 271 (13): 7551-7558 (1996). |
Weiss, R.A. and Clapham, P.R., “Hot Fusion of HIV”, Nature, 381:647-648 (1996). |
Deng, H., et al., “Identification of a Major Co-Receptor for Primary Isolates of HIV-1”, Nature, 381:661-666 (1996). |
Dragic, T., et al., “HIV-1 Entry Into CD4+ Cells is Mediated by the Chemokine Receptor CC-CKR-5”, Nature, 381:667-673 (1996). |
Hill, C.M. and Littman, D.R., “Natural Resistance to HIV?”, Nature, 382:668-669 (1996). |
Samson, M., et al., “Resistance to HIV-1 Infection in Caucasian Individuals Bearing Mutant Alleles of the CCR-5 Chemokine Receptor Gene”, Nature, 382:722-725 (1996). |
Doranz, B.J., et al., “A Dual-Tropic Primary HIV-1 Isolate That Uses Fusin and the β-Chemokine Receptors CKR-5, CKR-3, and CKR-2b as Fusion Cofactors”, Cell, 85:1149-1158 (1996). |
Feng, Y., et al., “HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor”, Science, 272:872-877 (1996). |
Cocchi, F., et al., “Identification of RANTES, MIP-1α, and MIP-1β as the Major HIV-Suppressive Factors Produced by CD8+ T Cells”, Science, 270:1811-1815 (1995). |
Alkhatib, G., et al., “CC CKR5: A RANTES, MIP-1α, MIP-1β Receptor as a Fusion Cofactor for Macrophage-Tropic HIV-1”, Science, 272:1955-1958 (1996). |
Förster, R. et al., “A General Method for Screening mAbs Specific for G-protein Coupled Receptors as Exemplified by Using Epitope Tagged BLR1-transfected 293 Cells and Solid-phase Cell ELISA”, Biochem. Biophys. Res. Commun., 196(3):1496-1503 (1993). |
Raport, C.J., et al., “New Members of Chemokine Receptor Gene Family”, J. Of Leukocyte Biol., 59:18-23 (1996). |
Combadiere, C., et al., “Cloning and Functional Expression of a Human Eosinophil CC Chemokine Receptor”, The Jour. of Biol. Chem., 270 (27):16491-16494 (1995). |
Wasniowska, K., et al., “Identification of the Fy6 Epitope Recognized by Two Monoclonal Antibodies in the N-Terminal Extracellular Portion of the Duffy Antigen Receptor for Chemokines”, Molec. Immunol., 33(11/12):917-923 (1996). |
Combadiere, C., et al., “Cloning and Functional Expression of CC CKR5, A Human Monocyte CC Chemokine Receptor Selective for MIP-1α, MIP-1β, and RANTES”, J. of Leukocyte Biol., 60:147-152 (1996). |
Ponath, P.D., et al., “Molecular Cloning and Characterization of a Human Eotaxin Receptor Expressed Selectively on Eosinophils”, J. Exp. Med., 183:2437-2448 (1996). |
Rudikoff, S., et al., “Single Amino Acid Substitution Altering Antigen-binding Specificity,” Proc. Natl. Acad. Sci. USA, 79:1979-1983 (1982). |
Wildner, G., and Thurau, S.R., “Database Screening for Molecular Mimicry”, Immunology Today, 18(5):252-253 (1997). |
Berzofsky, J.A. and Berkower, I.J., “Immunogenicity and Antigen Structure.” In Fundametal Immunology, Second Edition, W.E. Paul, ed. (NYL Raven Press Ltd.) pp. 169-208 (1989). |
Neote, K., et al., “Molecular Cloning, Functional Expression, and Signaling Characteristics of a C-C Chemokine Receptor”, Cell, 72:415-425 (1993). |
Endres, M.J., et al., “CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4”, Cell, 87:745-756 (1996). |
Su, S., et al., “Preparation of Specific Polyclonal Antibodies to a C-C Chemokine Receptor, CCR1, and Determination of CCR1 Expression on Various Types of Leukocytes”, J. of Leukocyte Bio., 60:658-666 (1996). |
Wu, Lijun, et al., “Interaction of Chemokine Receptor CCR5 with its Ligands: Multiple Domains for HIV-1 gp120 Binding and a Single Domain for Chemokine Binding”, J. Exp. Med., 186(8):1373-1381 (1997). |
Wu, Lijun, et al., “CCR5 Levels and Expression Pattern Correlate with Infectability by Macrophage-tropic HIV-1, In Vitro”, J. Exp. Med., 1859):1681-1691 (1997). |
Bleul, Conrad C., et al., “The HIV Coreceptors CXCR4 and CCR5 are Differentially Expressed and Regulated on Human T Lymphocytes”, Proc. Natl. Acad. Sci., 94:1925-1930 (1997). |
Doranz, Benjamin J., et al., “Two Distinct CCR5 Domains Can Mediate Coreceptor Usage by Human Immondeficiency Virus Type 1”, Journal of Virology, 71(9):6305-6314 (1997). |
Osbourn, J., et al., “Directed selection of MIP-1α neutralizing CCR5 antibodies from a phage display human antibody library”, Nature Biotechnology, 16: 778-781 (1998). |
Li, Y., et al., “Antibodies to Human G-Protein Chemokine Receptor HDGNR10 (CCR5 Receptor)”, U.S. patent application Publication No.: US2001/0000241A1, Publication Date: Apr. 12, 2001. |
Lee, B., et al., “Epitope Mapping of CCR5 Reveals Multiple Conformational States and Distinct but Overlapping Structures Involved n Chemokine and Coreceptor Function”, J. of Biol. Chem., 274(14): 9617-9629 (1999). |
Hill, C.M., et al., “The Amino Terminous of Human CCR5 is Required for its Functioin as a Receptor for Diverse Human and Simian Immunodeficiency Virus Evelope Glycoproteins”, Virology, 248: 357-371 (1998). |
Olson, W.C., et al. “Differential Inhibition of Human Immunodeficiency Virus Type 1 Fusion, gp120 Binding, and CC-Chemokine Activity by Monoclonal Antibodies to CCR5”, J. of Virology, 73 (5): 4145-4155 (1999). |
Gosling, J., et al., “Molecular uncoupling of C-C chemokine receptor 5-induced chemotaxis and signal transduction from HIV-1 coreceptor activity”, Cell Biology, 94:5061-5066 (1997). |
Frade, Jose M.R., et al., “Characterization of the CCR2 Chemokine Receptor: Functional CCR2 Receptor Expression in B Cells,” J. Immunol., 159(11):5576-5584 (1997). |
Atchison, R.E., et al., “Multiple Extracellular Elements of CCR5 and HIV-1 Entry: Dissociation from Response to Chemokines”, Science, 274:1924-1926 (1996). |