Claims
- 1. An isolated antibody that specifically binds a PTTG carboxy-terminal peptide selected from the group consisting of:
(A) peptides having an amino acid sequence consisting of SEQ. ID. NO.: 16; and (B) peptide fragments of SEQ ID NO: 16 that comprise at least 15 contiguous amino acid residues of SEQ ID NO: 16 and include a proline-rich region of SEQ ID NO: 16.
- 2. The isolated antibody of claim 1, wherein the antibody is a monoclonal antibody.
- 3. The isolated antibody of claim 1, wherein the antibody further comprises a detectable label.
- 4. The isolated antibody of claim 1, wherein the antibody is a Fab, a Fab′, a F(ab′)2, or a F(v) fragment of an immunoglobulin.
Parent Case Info
[0001] This application is a division of U.S. Non-provisional Application No. 09/569,956, filed on May 12, 2000, which is a continuation-in-part of U.S. Ser. No. 08/894,251, filed on Jul. 23, 1999, as a national stage application, under 35 U.S.C. § 371, of international application PCT/US97/21463, filed Nov. 21, 1997, which claims the priority of the filing date of U.S. Provisional Application Serial No. 60/031,338, filed Nov. 21, 1996. claims the benefit of U.S. Provisional Application No. 60/065825, filed on Nov. 14, 1997. This application is also related to U.S. Ser. No. 10/136,056, filed on Apr. 29, 2002, U.S. Ser. No. 10/136,082, filed on Apr. 29, 2002, U.S. Ser. No. 10/136,098, filed on Apr. 29, 2002, and U.S. Ser. No. 10/135,671, filed on Apr. 29, 2002, which are all divisions of U.S. Ser. No. 09/569,956.
Government Interests
[0002] The U.S. Government has a paid-up license in this invention and the right in limited circumstances to require the patent owner to license others on reasonable terms as provided for by the terms of Contract CA75979, awarded by the National Cancer Institute of the National Institutes of Health.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60031338 |
Nov 1996 |
US |
|
60065825 |
Nov 1997 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09569956 |
May 2000 |
US |
Child |
10261821 |
Sep 2002 |
US |
Continuation in Parts (1)
|
Number |
Date |
Country |
Parent |
08894251 |
Jul 1999 |
US |
Child |
09569956 |
May 2000 |
US |