Claims
- 1. An isolated antibody that specifically binds to a protein comprising a first polypeptide disulfide-bonded to a second polypeptide, wherein each of said polypeptides is a polypeptide as shown in SEQ ID NO:2 from amino acid residue X to amino acid residue 370, wherein X is 19, 246, 250, or 258.
- 2. The antibody of claim 1 wherein X is 19.
- 3. The antibody of claim 1 wherein X is 246.
- 4. The antibody of claim 1 wherein X is 250.
- 5. The antibody of claim 1 wherein X is 258.
- 6. The antibody of claim 1 which is a monoclonal antibody.
- 7. The antibody of claim 6 wherein X is 19.
- 8. The antibody of claim 6 wherein X is 246.
- 9. The antibody of claim 6 wherein X is 250.
- 10. The antibody of claim 6 wherein X is 258.
- 11. The antibody of claim 6 which is operably linked to a reporter molecule.
- 12. The antibody of claim 1 which is a single-chain antibody.
- 13. The antibody of claim 1 which is a humanized antibody.
- 14. The antibody of claim 1 which is operably linked to a reporter molecule.
CROSS-REFERENCE TO RELATED APPLICATIONS
[0001] This application is a divisional of U.S. application Ser. No. 09/876,813, filed Jun. 6, 2001, which is a divisional of U.S. application Ser. No. 09/564,595, filed May 3, 2000, now U.S. Pat. No. 6,495,668, which claims the benefit of U.S. Provisional Application Serial No. 60/132,250, filed May 3, 1999, U.S. Provisional Application Serial No. 60/164,463, filed Nov. 10, 1999 and U.S. Provisional Application Serial No. 60/180,169, filed Feb. 4, 2000.
Provisional Applications (3)
|
Number |
Date |
Country |
|
60132250 |
May 1999 |
US |
|
60164463 |
Nov 1999 |
US |
|
60180169 |
Feb 2000 |
US |
Divisions (2)
|
Number |
Date |
Country |
Parent |
09876813 |
Jun 2001 |
US |
Child |
10877623 |
Jun 2004 |
US |
Parent |
09564595 |
May 2000 |
US |
Child |
09876813 |
Jun 2001 |
US |