Patent Application
20220241050
The present invention relates to a cartridge for dispensing a material. The material to be dispensed may be a one-component material or a multi-component system material, e.g. a two-component system material comprising a powder component and a liquid component. In the latter case, the cartridge of the invention is advantageously suitable both for the mixing and the dispensing of the material. A cartridge according to the invention may be used, in particular, for the dispensing of a dental material.
Cartridges suitable for the mixing and dispensing of material are particularly interesting for dental restoration applications, in order to mix a multi-component dental restoration material and dispense it on a tooth of a subject. A dental restoration material classically comprises a powder component and a liquid component, which are mixed to form a dental cement. The steps of weighing each component and mixing the two components are tedious, hazardous and time-consuming. To overcome this issue, cartridges have been developed for dental restoration applications, in which certain amounts of a powder component and of a liquid component are previously weighed and accommodated in isolated chambers so as to prevent any accidental mixing of the two components. In such cartridges, the components can be released from the isolated chambers at a desired time and mechanically mixed with each other to form a dental cement that is dispensed from the cartridge.
For example, U.S. Pat. No. 6,386,872 B1 discloses a cartridge for dental restoration material, comprising successively a first tubular member, a second tubular member and a plunger located one inside the other, wherein the first tubular member contains a powder component and the second tubular member contains a liquid component, a dispensing nozzle being connected to the first tubular member. A first transverse wall separates the first tubular member and the second tubular member, whereas a second transverse wall separates the first tubular member and the nozzle. Upon applying a force on the plunger, an aperture is pierced in a rupturable portion of the first transverse wall, thus mixing the two components to form a dental restoration material. When it is moved further towards the nozzle, the plunger ruptures a rupturable portion of the second transverse wall, and the dental restoration material is dispensed from the nozzle. In such a cartridge, there is a risk that pieces of the rupturable portions migrate in the material during the dispensing, thus polluting the material. In addition, pieces of the rupturable portions may clog the nozzle and interfere with the dispensing of the material. Such a cartridge also has to be handled carefully in order to avoid uncontrolled dispensing of the material.
EP 2 692 308 A1 discloses a cartridge for the mixing and dispensing of material, comprising a body containing a main chamber, a dispensing nozzle, a liquid receptacle and a plunger having a forwardly projecting sharp protrusion. Upon depression of the plunger, the sharp protrusion ruptures a membrane of a front portion of the liquid receptacle, thus pushing hydraulically the liquid out of the liquid receptacle into the main chamber of the body to form a mixture with a powder contained in the main chamber. The front portion of the liquid receptacle is configured to be detached from the rest of the liquid receptacle by continued depression of the plunger, such that the plunger is able to traverse the entire length of the main chamber to rupture a membrane at the distal end of the main chamber and dispense the mixture from the main chamber into the dispensing nozzle. Such a cartridge comprising rupturable membranes that separate the liquid receptacle from the main chamber and the main chamber from the nozzle does not allow a fine control of hygrometry in each chamber. In the case of a powder highly sensitive to moisture, this limits the shelf life of the cartridge, since the powder in the main chamber is not properly protected from moisture. In addition, there is a risk that pieces of the ruptured membranes migrate in the material during the dispensing, thus polluting the material, or clog the nozzle and interfere with the dispensing of the material. Here again, the cartridge also has to be handled carefully to avoid uncontrolled dispensing of the material.
In the same way, problems of pollution of the material and clogging of the dispensing nozzle may arise in cartridges suitable for the dispensing of one-component materials, which are also subject to constraints in terms of sealing and maintaining a constant humidity level inside the chamber of the cartridge in the case of materials highly sensitive to moisture.
It is these drawbacks that the invention is intended more particularly to remedy by proposing a cartridge for dispensing a material which is easy to operate while making the dispensing of the material more secure, in particular by limiting the risks of polluting the material or clogging the dispensing nozzle, the cartridge also advantageously allowing a control of hygrometry in the cartridge, thus being compatible with long-term preservation of moisture sensitive materials. There is also a need for providing a cartridge for dispensing a material featuring good sealing properties, especially when delivering the material.
For this purpose, a subject of the invention is a cartridge for dispensing a material, comprising:
In a conventional manner, within the frame of the invention, the terms “proximal” and “distal” refer to a position of portions of the cartridge with reference to an operator (e.g. a dentist), i.e. the term “proximal” refers to a position closer to the operator of the cartridge, while the term “distal” refers to a position that is more distant from the operator.
In the cartridge of the invention, the distal wall of the barrel is broken by means of the internal piercing element when the barrel moves from the first position to the second position, which corresponds to a transition of the cartridge to a dispensing configuration. Thanks to the specific arrangement of the piercing element in the vicinity of the dispensing hole, the force applied by the piercing element on the distal wall of the barrel is oriented in a direction away from a dispensing nozzle connected to the dispensing hole, so that the broken parts of the distal wall of the barrel are pushed away from the nozzle. In this way, the risks of polluting the material to be dispensed or clogging the nozzle are efficiently reduced. The cartridge of the invention also allows a control of hygrometry in the chamber of the barrel, which is hermetically sealed by the piston, thus being compatible with the storage of moisture sensitive materials. Examples of moisture sensitive materials that are to be kept in a controlled environment with low hygrometry include, in a non-limitative manner: powder components of multi-component dental restoration materials, intended to be stored separately and mixed extemporaneously with a liquid; one-component materials such as calcium sulphate-based cements or calcium silicate-based cements.
According to one embodiment, the piercing element is a tubular element projecting internally from the distal wall of the sleeve, said piercing element being in fluid communication with the dispensing hole. Thanks to this arrangement, once the distal wall of the barrel has been broken, the tubular piercing element forms a privileged passageway guiding the material from the barrel directly to the dispensing hole, which limits the losses of material in the interspace between the barrel and the sleeve.
According to one embodiment, the inner diameter of the piercing element is higher than or equal to the diameter of the dispensing hole. In this way, the opening created in the distal wall of the barrel under the action of the piercing element has a size suitable to ensure proper flow of the material to be dispensed, which is particularly important for the dispensing of a pasty material.
According to one embodiment, the sleeve comprises an annular cavity around the piercing element, the annular cavity being delimited peripherally by a beveled inner surface complementary to a corresponding beveled outer surface of the barrel. The complementary beveled surfaces provide an efficient sealing at the interface between the barrel and the sleeve, close to the piercing element and the dispensing hole, which limits the passage of material in the interspace between the barrel and the sleeve, thus ensuring optimal dispensing control.
According to one embodiment, the distal wall of the barrel comprises a central breakable portion surrounded by the sealing portion, the ratio of the surface area of the breakable portion to the surface area of the sealing portion being such that, after opening, the fins of the open breakable portion leave the dispensing hole of the sleeve completely cleared, while the bearing surface of the sealing portion is sufficiently thin to limit the contact area. In this way, the seal is easier to achieve with the distal wall of the sleeve and the contact pressure is maximized to ensure sealing during the dispensing of the material. In particular, the relative dimensions of the breakable portion and the sealing portion are advantageously configured to ensure a proper flow of the material to be dispensed while limiting the material losses.
According to one embodiment, the distal wall of the barrel comprises at least one weakened portion having a thickness lower than the thickness of the rest of the distal wall. Preferably, the distal wall of the barrel comprises a plurality of weakened portions distributed on the breakable portion, so as to guide a specific deformation of the distal wall of the barrel when it is submitted to the action of the piercing element. In one embodiment, the weakened portions are weakened lines distributed around a central portion of the distal wall of the barrel, so as to guide a deformation of the distal wall in a corolla shape oriented away from a dispensing nozzle connected to the dispensing hole. In a particular embodiment, the weakened portions comprise weakened lines distributed radially starting from a central portion of the distal wall of the barrel, notably according to a star shape.
Advantageously, the distal wall of the barrel is broken under the action of the piercing element without detachment of pieces thereof that may pollute the material or clog the nozzle connected to the dispensing hole. More specifically, the distal wall of the barrel is configured so that the thrust force applied by the piercing element opens the distal wall at the weakened portions and deforms the portions of the distal wall surrounding the openings thus formed.
According to one embodiment, the barrel is made of a material having a Water Vapor Transfer Rate (WVTR) at 23° C. and 85% relative humidity (RH), for a film thickness of 100 μm, of less than 0.5 g/(m2-day), preferably less than 0.4 g/(m2-day), such as a cyclic olefin copolymer (COC), a cyclic olefin polymer (COP), polypropylene (PP), high-density polyethylene (HDPE). A barrel made of such a low WVTR material makes it possible to maintain a constant humidity level in the chamber, in particular a humidity level suitable to protect a moisture sensitive material contained therein, such as a moisture sensitive powder component of a multi-component dental restoration material, or a moisture sensitive one-component material.
According to one embodiment, the barrel comprises at least one tab near its proximal end configured to cooperate with a corresponding housing of the sleeve to lock the barrel in the first position with respect to the sleeve. In this way, the cartridge comprises a locking system ensuring that the distal wall of the barrel can be broken only when the or each tab of the barrel is disengaged from the corresponding housing of the sleeve. Thus, in the locked configuration, the cartridge can be manipulated without any risk of undesired dispensing of the material, which is particularly useful when a mixing step is required prior to the dispensing step, as is the case for a cartridge intended for the dispensing of a multi-component system material.
According to one embodiment, the barrel comprises at least one outer radial feature configured to cooperate with at least one inner radial feature of the sleeve to keep the barrel in the first position with respect to the sleeve, even when the or each tab of the barrel is disengaged from the corresponding housing of the sleeve. Such cooperating radial features between the barrel and the sleeve make it possible to secure the cartridge in a storage configuration even when the locking system is not active. According to one embodiment, the barrel comprises at least two outer radial features configured to cooperate with at least two inner radial features of the sleeve to keep the barrel in the first position with respect to the sleeve.
According to one embodiment, the sleeve comprises at least one, two, three or four longitudinal groove(s) near the proximal end configured to guide the displacement of a tab of the barrel when the barrel is moved from the first position to the second position. The or each longitudinal groove guides the barrel towards the piercing element and improves the stability of the displacement of the barrel to reach the dispensing configuration of the cartridge.
According to one embodiment, the barrel comprises at least one, two, three or four inner radial feature(s) configured to cooperate with at least one, two, three or four outer radial feature(s) of the piston to keep the plate of the piston at a distance from the distal wall of the barrel before the piston is moved towards the distal wall of the barrel for the dispensing of the material. Such cooperating radial features between the barrel and the piston make it possible to have a two-step transition of the cartridge towards the dispensing configuration, obtained through the application of one and the same thrust force on the proximal end of the piston, i.e. including: a first step of initiating the dispensing of the material, in which the barrel is displaced relative to the sleeve from the first position to the second position, until the distal wall of the barrel is in contact with the distal wall of the sleeve and broken by the piercing element, the radial features between the barrel and the piston being mutually engaged in this first step so that the barrel and the piston move integrally with each other; and a second step of dispensing the material through the dispensing nozzle, in which the piston is displaced relative to the barrel, the radial features between the barrel and the piston being mutually disengaged in this second step. The transition from the first step to the second step happens automatically under the action of the thrust force, since the cooperation between the inner radial features of the barrel and the outer radial features of the piston is released once the distal wall of the barrel is in contact with the distal wall of the sleeve. According to one embodiment, the thrust force ranges from 50 N to more than 400 N, preferably from 50 N to 400 N, preferably from 200 N to 400 N.
According to one feature, the cartridge comprises a dispensing nozzle connected to the dispensing hole. The dispensing nozzle may be formed in one piece with the sleeve of the cartridge, or the dispensing nozzle may be attached to the sleeve of the cartridge by any appropriate means, for example by means of a Luer Lock connector. According to one embodiment, the cartridge comprises a deformable dispensing nozzle connected to the dispensing hole, wherein the thickness of the wall of the dispensing nozzle decreases from the dispensing hole toward a free end of the dispensing nozzle. According to one embodiment, the thickness of the wall of the dispensing nozzle ranges from 0.1 mm to 2 mm, preferably from 0.6 mm to 1.6 mm Such a geometry of the dispensing nozzle, combined with the selection of an appropriate material for the dispensing nozzle, makes it possible to have an orientable nozzle having a constant internal diameter, even when it is bent. Examples of suitable materials for the dispensing nozzle include polyesters, polycarbonate, polyamide, polypropylene, high-density polyethylene. According to one embodiment, the suitable materials for the dispensing nozzle comprise or consists of polyesters, polycarbonate, polyamide, polypropylene, high-density polyethylene or copolymers thereof.
According to one embodiment, the piston comprises a distal rod configured to be received in an internal volume of the piercing element when the cartridge is in a configuration of end of distribution of the material. The distal rod configured to enter the tubular piercing element makes it possible to push the material to be dispensed as far as possible towards the dispensing hole and nozzle, thus limiting the losses of material.
According to one embodiment, the piston comprises a combination of a receptacle and a plunger, the receptacle defining a chamber and comprising a proximal open end and an openable distal wall, the plunger being movable in the chamber of the receptacle and comprising a distal rod configured to apply a pressure on the openable distal wall. A cartridge comprising such a two-part piston is suitable for the dispensing of a two-component material, in particular a material comprising a powder component initially hermetically received in the chamber of the barrel and a liquid component initially hermetically received in the chamber of the receptacle, the components being mixed with each other at a desired time to form the material to be dispensed, by opening the openable distal wall of the receptacle through application of a pressure thereon with the distal rod of the plunger.
According to one embodiment, the openable distal wall of the receptacle comprises a detachable portion attached to the rest of the distal wall by an annular connecting part having a solid portion extending over an angle of between 30° and 90°, preferably between 40° and 80°, more preferably of the order of 60°, and a weakened portion having a thickness less than the thickness of the solid portion, so as to form a hinge. This arrangement makes it possible to open the distal wall of the receptacle by rupturing only the weakened portion of the annular connecting part, whereas the detachable portion remains connected to the rest of the distal wall of the receptacle through the solid portion, which plays the role of a hinge. In this way, the detachable portion remains attached to the rest of the distal wall of the receptacle in the open configuration of the distal wall, i.e. the distal wall of the receptacle can be open under the action of the distal rod of the plunger without detachment of pieces that may pollute the material to be dispensed or clog the dispensing nozzle connected to the dispensing hole of the cartridge.
According to one embodiment, the receptacle comprises at least one inner radial feature configured to cooperate with at least one outer radial feature of the plunger to keep the plunger at a distance from the openable distal wall of the receptacle in a storage configuration of the cartridge, the cooperation between the inner radial feature and the outer radial feature of the plunger being releasable under the effect of a thrust force applied on the proximal end of the plunger. Such cooperating radial features between the receptacle and the plunger make it possible to secure the cartridge containing a two-component material in a storage configuration where the two components are separated, one being received in the chamber of the barrel while the other is received in the chamber of the receptacle, without risk of accidental mixing of the two components.
Another subject of the invention is a method of dispensing a material by means of a cartridge as described above, comprising steps in which:
Features and advantages of the invention will become apparent from the following description of several embodiments of a cartridge according to the invention, this description being given merely by way of example and with reference to the appended drawings in which:
The sleeve 2 comprises a body 21 including a proximal open end 211 and a distal end 212 defined by a distal wall 22 of the sleeve. The distal wall 22 is provided with a dispensing hole 23, from which extends a tubular dispensing nozzle 20 formed in one piece with the body 21 of the sleeve. As can be seen in the longitudinal section of
The distal wall 22 of the sleeve 2 comprises an internal piercing element 29 in the alignment of the dispensing hole 23, which is intended to break a breakable distal wall 39 of the barrel 3. The piercing element 29 is a tubular element projecting internally from the distal wall 22 of the sleeve so as to be in fluid communication with the dispensing hole 23. Thanks to this arrangement, once the distal wall 39 of the barrel 3 has been broken, the tubular piercing element 29 forms a privileged passageway guiding the material contained in the barrel 3 directly to the dispensing hole 23, which limits the losses of material in the interspace between the barrel 3 and the sleeve 2.
As shown in
As visible in
As clearly visible in
The diameters of the breakable portion 390 and the piercing element 29 are also adjusted to maximize the breakage efficiency of the piercing element 29. For example, in the illustrated example, the diameter d29 of the piercing element 29 is of the order of half the diameter d390 of the breakable portion 390. As shown in
This arrangement of the weakened lines 392 is configured to guide a deformation of the distal wall 39 of the barrel, when it is submitted to the action of the piercing element 29, in a corolla shape oriented away from the dispensing nozzle 20. In practice, the rupture of the distal wall 39 is obtained through a displacement of the barrel 3 in the sleeve 2 along the longitudinal axis X-X′ between a first position, visible in
The barrel 3 also comprises two diametrically opposed tabs 38 near its proximal end 31. Each tab 38 is configured to be received in a corresponding housing 278 defined by a locking wing 27 of the sleeve 2 arranged near the proximal end 21, so as to lock the barrel 3 in the first position with respect to the sleeve 2. This locked configuration of the cartridge 1 ensures that the distal wall 39 of the barrel 3 remains at the distance e1 from the distal wall 22 of the sleeve, so that the cartridge 1 can be manipulated without any risk of the distal wall 39 being pierced by the piercing element 29, which makes it possible to implement a mixing step prior to the dispensing step.
In addition, the barrel 3 comprises an outer radial collar 36 configured to cooperate with inner radial recesses 256 formed by six clipping members 25 distributed circumferentially inside the body 21 of the sleeve 2. The cooperation between the outer radial collar 36 and the inner radial recesses 256 makes it possible to keep the barrel 3 in the first position with respect to the sleeve 2 even when the tabs 38 are disengaged from the housings 278, thus allowing the cartridge 1 to be secured in a storage configuration even when the locking system 38/278 is not active.
As can be seen particularly in
The chamber 35 of the barrel 3 is sealed by means of a piston formed by the combination of the liquid receptacle 4 and the plunger 5. In this illustrative example, the receptacle 4 is made of low-density polyethylene (LDPE) and the plunger 5 is made of acrylonitrile butadiene styrene (ABS). As shown in
The receptacle 4 is configured to move in sealing engagement in the chamber 35 of the barrel 3. To this end, the receptacle 4 is provided externally with a peripheral sealing rib 43 configured to prevent the passage of the liquid component, initially contained in the chamber 45 of the receptacle 4, toward the interspace between the barrel 3 and the receptacle 4, when the distal wall 47 of the receptacle is open and the receptacle 4 is moved towards the distal wall 39 of the barrel.
In practice, the opening of the distal wall 47 of the receptacle 4 is obtained thanks to a rod 59 extending distally from the distal wall 52 of the plunger 5. More precisely, the chamber 45 of the receptacle 4 is sealed by means of the plunger 5, which is movable in the chamber 45 and whose distal rod 59 is configured to apply a pressure on the detachable portion 48 of the distal wall 47 of the receptacle. Before the opening of the distal wall 47, the powder component is hermetically received in the chamber 35 of the barrel 5 and the liquid component is hermetically received in the chamber 45 of the receptacle 4. The two components can then be easily mixed together at a desired time, so as to form the material to be dispensed, by opening the openable distal wall 47 of the receptacle through application of a pressure on the detachable portion 48 with the distal rod 59 of the plunger and applying a vibration to the cartridge 1 in this activated configuration, either manually or by means of a vibration mixer.
The receptacle 4 comprises two inner peripheral grooves 46, 46′ configured to cooperate with two corresponding outer peripheral ribs 56, 56′ of the plunger 5 to keep the plunger 5 at a distance e2 from the openable distal wall 47 of the receptacle 4 in a storage configuration of the cartridge 1. The cooperation between the inner peripheral grooves 46, 46′ and the outer peripheral ribs 56, 56′ is releasable under the effect of a thrust force F0 applied on the proximal end 51 of the plunger 5, e.g. by means of an activation machine. The cooperating radial features 46, 56 and 46′, 56′ between the receptacle 4 and the plunger 5 make it possible to secure the cartridge 1 in the storage configuration where the powder component and the liquid component are separated, the first one being received in the chamber 35 of the barrel while the second one is received in the chamber 45 of the receptacle, without risk of accidental mixing of the two components.
The barrel 3 also comprises an inner peripheral groove 34 near its proximal end 31, which is configured to cooperate with an outer peripheral rib 44 of the receptacle 4 to keep the distal wall 47 of the receptacle 4 at a distance from the distal wall 39 of the barrel 3 before the piston formed by the combination of the receptacle 4 and the plunger 5 is moved towards the distal wall 39 of the barrel for the dispensing of the material. The cooperating radial features 34, 44 between the barrel 3 and the receptacle 4 make it possible to have a two-step transition of the cartridge 1 towards the dispensing configuration, obtained through the application of a thrust force F1 on the proximal end 51 of the plunger 5, e.g. by means of a dispensing apparatus.
More specifically, in a first step of initiating the dispensing of the material, the barrel 3 is displaced relative to the sleeve 2 from the first position to the second position, until the distal wall 39 of the barrel is in contact with the distal wall 22 of the sleeve and broken by the piercing element 29. In this first step, the radial features 34, 44 between the barrel 3 and the receptacle 4 are mutually engaged so that the barrel 3, the receptacle 4 and the plunger 5 move integrally with one another. In a second step of dispensing the material through the dispensing nozzle, the piston formed by the combination of the receptacle 4 and the plunger 5 is displaced relative to the barrel 3, the radial features 34, 44 between the barrel 3 and the receptacle 4 being mutually disengaged in this second step.
A method of dispensing a two-component material by means of the cartridge 1 according to the invention, where the two-component material comprises a powder component, initially received in the chamber 35 of the barrel 3, and a liquid component, initially received in the chamber 45 of the receptacle 4, comprises steps as described below.
Initially, the cartridge 1 is in the storage configuration shown in
Then, a thrust force F0 is applied on the proximal end 51 of the plunger 5, e.g. by means of an activation machine, so that the distal rod 59 of the plunger 5 applies a pressure on the detachable portion 48 of the distal wall 47 of the receptacle 4, thus reaching the activated configuration shown in
Once the two components have been mixed together, the assembly comprising the barrel 3, the receptacle 4 and the plunger 5, united in rotation, is turned relative to the sleeve 2 in the direction of the arrow R of
In a second step of dispensing the material through the dispensing nozzle, under the action of the thrust force F1, the radial features 34, 44 between the barrel 3 and the receptacle 4 are mutually disengaged, and the piston formed by the combination of the receptacle 4 and the plunger 5 is displaced relative to the barrel 3. The transition from the first step to the second step happens automatically under the action of the thrust force F1, the cooperation between the radial features 34, 44 being released once the distal wall 39 of the barrel 3 is in contact with the distal wall 22 of the sleeve 2. In the configuration of end of distribution of the material, visible in
In the second embodiment shown in
In the third embodiment shown in
A method of dispensing a material by means of the cartridge 101 or 201 is analogous to the method described above for the cartridge 1, only omitting the steps of mixing two components. Indeed, in the second and third embodiments, the material to be dispensed, which is received in the chamber 35 of the barrel 3, is ready to use. Initially, the cartridge 101 or 201 is in a configuration shown in
In a first step of initiating the dispensing of the material, under the action of the thrust force F1, the barrel 3 is displaced relative to the sleeve 2 from the first position to the second position, until the distal wall 39 of the barrel is in contact with the distal wall 22 of the sleeve and broken by the piercing element 29. In this first step, the barrel 3 and the piston 105 or 205 move integrally with one another thanks to the cooperation of the radial features 34 and 154, 254. In a second step of dispensing the material through the dispensing nozzle, under the action of the thrust force F1, the radial features 34 and 154, 254 are mutually disengaged, and the piston 105 or 205 is displaced relative to the barrel 3. The transition from the first step to the second step happens automatically under the action of the thrust force F1, the cooperation between the radial features 34 and 154, 254 being released once the distal wall 39 of the barrel 3 is in contact with the distal wall 22 of the sleeve 2.
The invention is not limited to the examples described and shown. In particular, other materials and shapes than those described above can be considered for the constitutive members of a cartridge according to the invention.
| Number | Date | Country | Kind |
|---|---|---|---|
| 19187180.5 | Jul 2019 | EP | regional |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/EP2020/070358 | 7/17/2020 | WO | 00 |
