The present invention relates, in a first aspect, to a system comprising an electronic apparatus, comprising an electronic device constituting a capacitor that is used for charge sensing purposes and shows quantum capacitance, and a read-out circuit providing an improved read-out.
A second aspect of the present invention relates to an electronic apparatus like the one of the system of the first aspect of the invention, and adapted to allow the implementation of the improved read-out.
Systems which comprise the features of the preamble clause of claim 1 of the present invention are known in the art, i.e. those which comprise an electronic apparatus comprising:
The following documents disclose different prior art electronic devices including a 2-dimensional charge sensing layer configured to sense electrical charges and/or electrical charge density changes induced by an external physical quantity:
The read-out circuits of the systems of the prior art are clearly improvable. Therefore, it is necessary to provide an alternative to the state of the art, by providing a system including an improved read-out circuit which provides an improved reading of the read-out signal.
To that end, the present invention relates, in a first aspect, to a system comprising an electronic apparatus, wherein the electronic apparatus comprises:
In contrast to the systems of the prior art, in the one proposed by the first aspect of the present invention, the read-out circuit comprises:
For an embodiment, the read-out circuit further comprises a first offset correction mechanism comprising said means which are configured and arranged to select and apply a first reference voltage to a second plate of the reference capacitor Cref, so that the output voltage on the first input of the amplifier is zero when there is no induced electrical charge or electrical charge carrier density on the charge sensing structure.
For an embodiment, said means comprises at least one voltage source that generates at least said control voltage and, preferably, also the first reference voltage.
The terms “voltage source” must be interpreted in the present invention as any kind of real-world voltage source (i.e. with non-zero internal resistance and output impedance) known in the prior art, such as one comprising or formed by one or more battery cells, by one or more voltage generators, etc., for providing one (at least the above mentioned control voltage), two (the above mentioned control voltage and first reference voltage) or any number of voltages.
For an implementation of said embodiment, the output of the voltage source is electrically connected to the gate electrode structure or charge sensing structure, whether directly or through a switch, to apply the control voltage thereto, and, preferably to the second plate of the reference capacitor Cref, whether directly or through a switch, to apply the control voltage thereto.
For a preferred embodiment, the above mentioned means comprises a control unit configured and arranged to select and apply at least the control voltage.
According to different embodiments, the control voltage is a DC voltage, an AC voltage, or a combination of DC and AC voltages (such as an AC voltage superimposed on a DC offset, or any kind of frequency and/or temporal combination).
For an embodiment, the control unit is configured to select the properties of the control voltage, at least regarding its magnitude, while for another embodiment for which the control voltage includes an AC voltage, the control unit is configured to select the properties of the control voltage also regarding its frequency and/or phase, and while for a further embodiment for which the control voltage includes an DC voltage, the control unit is configured to select the properties of the control voltage also regarding its polarity.
According to a further embodiment, the said read-out circuit further comprises a second offset correction mechanism comprising the above mentioned means which are configured and arranged to select and apply to a second input of the amplifier a second reference voltage with a magnitude equal or substantially equal to the output voltage when the charge sensitivity structure is set to its most sensitivity point and there is no electrical charge or electrical charge carrier density induced by the external physical quantity.
According to different embodiments, the first and/or second reference voltages is a DC voltage, an AC voltage, or a combination of DC and AC voltages.
For an embodiment, the control unit is configured to select the properties of the first and/or second reference voltage, at least regarding its magnitude, while for another embodiment for which the first and/or second reference voltage includes an AC voltage, the control unit is configured to select the properties thereof also regarding its frequency and/or phase.
For an embodiment, the read-out circuitry includes a reset circuit to discharge the total capacitance Ctot, preferably under the control of the control unit.
The gate electrode structure together with the dielectric and charge sensing structures arranged there over, is arranged, for an embodiment, on a substrate.
According to an embodiment of the system of the first aspect of the present invention, the control unit further comprises an adjustment input connected to an output of the read-out circuit, and is configured to implement a closed-loop adjustment process to adjust the control voltage and/or the first and/or second reference voltage based on a read-out signal received through that adjustment input, and preferably also based on reference or set-point values with which the detected read-out signal(s) are compared. For an embodiment, the reference capacitor Cref is a separate component (i.e. a component not implemented by the electronic device itself but electrically connected thereto), with respect to the electronic device, while for an alternative embodiment, the reference capacitor Cref is implemented by the electronic device, with its first plate constituted by the charge sensing structure, a dielectric structure constituted by the sensitizing or functionalizing structure, and its second plate constituted by a top electrode structure arranged over the sensitizing or functionalizing structure.
According to an embodiment, electronic device and at least part of the read-out circuitry (for example an input transistor of the amplifier) are CMOS-implemented.
According to some embodiments, the electronic device of the electronic apparatus of the system of the first aspect of the present invention further comprises a sensitizing or functionalizing structure arranged over the charge sensing structure, wherein the sensitizing or functionalizing structure is configured to induce the electrical charge carriers and/or modify the charge carrier density therein induced by said external physical quantity. Generally the sensitizing or functionalizing structure is only sensitive to said external physical quantity.
The term “functionalizing” means for the present invention, to add a species to the charge sensing structure that not only provides a sensitizing function, but also adds another functionality. For example, in the paper by Wangyang Fu (Wangyang Fu, Lingyan Feng, Gregory Panaitov, et al., Biosensing near the neutrality point of graphene, Science Advances 3, e1701247, (2017).) a pPNA linker molecule is added to the surface of the graphene to allow ssDNA to link to the graphene and a Tween 20 molecule was added to the graphene surface to make the sensing of the ssDNA more specific by inhibiting attachment of other species to the surface of the graphene. Hence in this case the pPNA linker molecule functionalizes AND sensitizes the graphene.
While the term “sensitizing” refers to any species that is added on top of the charge sensing structure that sensitizes it to an external physical quantity or analyte.
For an embodiment, said sensitizing or functionalizing structure is a photoactive structure configured and arranged to, upon illumination, generate electron-hole pairs which, due to a field created by either a Schottky junction between the charge sensing structure and the photoactive structure or a top gate electrode on top of the photoactive structure or an interlayer between the charge sensing structure and the photoactive structure, are separated and either the electrons or holes gets transported, as said induced electrical charge carriers, to the charge sensing structure, so that the optoelectronic apparatus constitutes a photodetector or an image sensor.
For an implementation of that embodiment, the system of the first aspect of the present invention implements an image sensor comprising an array of pixels, wherein the electronic apparatus comprises a plurality of the above mentioned electronic devices each constituting one pixel of said array of pixels, implementing different alternative read-out schemes, for addressing and reading the pixels of the rows and columns of the array, including rolling and global shutter, etc.
According to an alternative embodiment, the electronic device is absent of any sensitizing or functionalizing structure arranged over the charge sensing structure, the charge sensing structure being configured to undergo a change in the electrical charge carriers and/or modify the charge carrier density therein induced by the external physical quantity.
Therefore, the present invention is generally applied to sensing devices that rely sensing a change in the electrical charge carriers and/or in the charge carrier density in the charge sensing structure induced by said external physical quantity, whether directly on an exposed charge sensing structure, through the intermediation of a sensitizing layer (such as a photo-sensitizing layer, for example made up of PbS colloidal quantum dots, where light can induce the charge carriers in the charge sensing structure, or a linker biomolecule grafted on the charge sensing structure) or through the functionalization of the charge sensing structure (e.g. for biosensing).
The charge sensing structure of the electronic device of the electronic apparatus of the system of the first aspect of present invention comprises one or more 2-dimensional charge sensing layers made of, for example, one or more of the following materials: single or few layer graphene (pure graphene, modified graphene, or functionalized graphene), black phosphorus, MoS2, WS2, WSe2, etc.
Different physical quantities or analytes can be sensed by the electronic apparatus of the system of the first aspect of the invention, as long as they induce electrical charge carriers in the charge sensing structure and/or a change in the charge carrier density therein, such as light, gas molecules or sensing neuronal signals. The analyte of interest transfers charge to the charge sensing structure or induces an electric field that modifies the charge carrier density thereof.
Another application is for direct sensing of in vivo electrical signals, or for implementing biosensors using chemically bonded linker molecules that enhance the selectivity for specific bio-molecules. When the molecule of interest binds to the linker, it transfer charge to the charge sensing structure or induces an electric field therein that modifies its charge carrier density.
A second aspect of the present invention relates to an electronic apparatus, comprising:
In contrast to the electronic apparatuses of the prior art, in the one of the second aspect of the present invention the read-out circuit comprises:
and in that the electronic apparatus further comprises at least a first input terminal electrically connected to the one of said gate electrode structure and said charge sensing structure which is not electrically connected to the first input of the amplifier;
wherein said first input terminal is accessible to apply thereto a control voltage which is selected such that the fermi level of the charge sensing structure is tuned to the most sensitive point;
so that when said total capacitance Ctot changes due to a change in the quantum capacitance Cq caused by an electrical charge or electrical charge carrier density induced on the charge sensing structure, an imbalance between the total capacitance Ctot and the reference capacitance Cref results in a change on the output voltage Vo on the first input of the amplifier that is amplified to provide the read-out signal So.
The embodiments described in the present document regarding the electronic apparatus of the system of the first aspect of the present invention are valid for describing corresponding embodiments of the electronic apparatus of the second aspect of the present invention.
In the following some preferred embodiments of the invention will be described with reference to the enclosed figures. They are provided only for illustration purposes without however limiting the scope of the invention.
As shown in those figures, the read-out circuit comprises:
so that when said total capacitance Ctot changes due to a change in the quantum capacitance Cg caused by an electrical charge or electrical charge carrier density induced on the charge sensing structure CE, an imbalance between the total capacitance Ctot and the reference capacitance Cref results in a change on the output voltage Vo on the first input of the amplifier A that is amplified to provide the read-out signal So.
As shown
Also, for the embodiments illustrated in
As shown in
The classical capacitance of the CSD is given by the following formula:
C
g=εrε0A/d
Where εr is the relative permittivity of the dielectric material, ε0 is the vacuum permittivity, A the area of the capacitor and d the thickness of the dielectric material.
For 2-dimensional materials there is another capacitance that needs to be taken into account due to their finite density of states. This is the quantum capacitance Cq. Cq is in series with the classical capacitance and thus reduces the total capacitance Ctot of the system (1/Ctot=1/Cg+1/Cq). The quantum capacitance is in general a function of the fermi level in the system, so it can be tuned by an external electric field, or a charge induced in the system by an external physical quantity.
When the 2-dimensional material is graphene, the quantum capacitance per unit area Cq/A is described as follows:
Where e is the electron charge, h the planck constant, vF the Fermi velocity of graphene, nG the induced carrier density in the graphene and n* the residual impurity density.
When Ctot changes due to the charge or charge carrier density induced on the charge sensing electrode, an imbalance in the capacitor system results in a voltage change Vo on the input of the amplifier A.
V
o
=C
tot/(Cref+Ctot)*(Vg−Vref1)+Vref1
Amplifier A then amplifies the output voltage Vo to output signal So.
In case the sensing electrode is made up of (few layer) graphene, this is at the charge neutrality point or dirac point. The output voltage Vo of the structure is measured by the amplifier A with respect to Vref2. Vref2 needs to be set such that it is equal (or substantially equal) to the output voltage Vo when the charge sensing electrode CE is set to its most sensitive point and there is no charge or charge carrier density induced by the external physical quantity.
For the third embodiment, i.e. that illustrated in
The stacked up structure of the electronic device of said third embodiment is shown in
Also for the third embodiment, as shown in
The layout of the second embodiment, illustrated in
In
A person skilled in the art could introduce changes and modifications in the embodiments described without departing from the scope of the invention as it is defined in the attached claims.
Number | Date | Country | Kind |
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19382068.5 | Jan 2019 | EP | regional |
Filing Document | Filing Date | Country | Kind |
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PCT/EP2020/052450 | 1/31/2020 | WO | 00 |