Claims
- 1. A purified or isolated nucleic acid comprising the sequence of one of SEQ ID NOs: 24-73 or a sequence complementary thereto.
- 2. A purified or isolated nucleic acid comprising at least 12 consecutive bases of the sequence of one of SEQ ID NOs: 24-73 or one of the sequences complementary thereto.
- 3. A purified or isolated nucleic acid comprising the full coding sequences of one of SEQ ID NOs: 24-73, wherein the full coding sequence comprises the sequence encoding signal peptide and the sequence encoding mature protein.
- 4. A purified or isolated nucleic acid comprising the nucleotides of one of SEQ ID NOs: 24-73 which encode a mature protein.
- 5. A purified or isolated nucleic acid comprising the nucleotides of one of SEQ ID NOs: 24-73 which encode the signal peptide.
- 6. A purified or isolated nucleic acid encoding a polypeptide having the sequence of one of the sequences of SEQ ID NOs: 74-123.
- 7. A purified or isolated nucleic acid encoding a polypeptide having the sequence of a mature protein included in one of the sequences of SEQ ID NOs: 74-123.
- 8. A purified or isolated nucleic acid encoding a polypeptide having the sequence of a signal peptide included in one of the sequences of SEQ ID NOs: 74-123.
- 9. A purified or isolated protein comprising the sequence of one of SEQ ID NOs: 74-123.
- 10. A purified or isolated polypeptide comprising at least 10 consecutive amino acids of one of the sequences of SEQ ID NOs: 74-123.
- 11. An isolated or purified polypeptide comprising a signal peptide of one of the polypeptides of SEQ ID NOs: 74-123.
- 12. An isolated or purified polypeptide comprising a mature protein of one of the polypeptides of SEQ ID NOs: 74-123.
- 13. A method of making a protein comprising one of the sequences of SEQ ID NO: 74-123, comprising the steps of:
obtaining a cDNA comprising one of the sequences of sequence of SEQ ID NO: 24-73; inserting said cDNA in an expression vector such that said cDNA is operably linked to a promoter; and introducing said expression vector into a host cell whereby said host cell produces the protein encoded by said cDNA.
- 14. The method of claim 13, further comprising the step of isolating said protein.
- 15. A protein obtainable by the method of claim 14.
- 16. A host cell containing a recombinant nucleic acid of claim 1.
- 17. A purified or isolated antibody capable of specifically binding to a protein having the sequence of one of SEQ ID NOs: 74-123.
- 18. In an array of polynucleotides of at least 15 nucleotides in length, the improvement comprising inclusion in said array of at least one of the sequences of SEQ ID NOs: 24-73, or one of the sequences complementary to the sequences of SEQ ID NOs: 24-73, or a fragment thereof of at least 15 consecutive nucleotides.
- 19. A purified or isolated nucleic acid of at least 15 bases capable of hybridizing under stringent conditions to the sequence of one of SEQ ID NOs: 24-73 or a sequence complementary to one of the sequences of SEQ ID NOs: 24-73.
- 20. A purified or isolated antibody capable of binding to a polypeptide comprising at least 10 consecutive amino acids of the sequence of one of SEQ ID NOs: 74-123.
- 21. A computer readable medium having stored thereon a sequence selected from the group consisting of a cDNA code of SEQID NOs. 24-73 and a polypeptide code of SEQ ID NOs. 74-123.
- 22. A computer system comprising a processor and a data storage device wherein said data storage device has stored thereon a sequence selected from the group consisting of a cDNA code of SEQID NOs. 24-73 and a polypeptide code of SEQ ID NOs. 74-123.
- 23. The computer system of claim 22 further comprising a sequence comparer and a data storage device having reference sequences stored thereon.
- 24. The computer system of claim 23 wherein said sequence comparer comprises a computer program which indicates polymorphisms.
- 25. The computer system of claim 22 further comprising an identifier which identifies features in said sequence.
- 26. A method for comparing a first sequence to a reference sequence wherein said first sequence is selected from the group consisting of a cDNA code of SEQID NOs. 24-73 and a polypeptide code of SEQ ID NOs. 74-123 comprising the steps of:
reading said first sequence and said reference sequence through use of a computer program which compares sequences; and determining differences between said first sequence and said reference sequence with said computer program.
- 27. The method of claim 26, wherein said step of determining differences between the first sequence and the reference sequence comprises identifying polymorphisms.
- 28. A method for identifying a feature in a sequence selected from the group consisting of a cDNA code of SEQID NOs. 24-73 and a polypeptide code of SEQ ID NOs. 74-123 comprising the steps of:
reading said sequence through the use of a computer program which identifies features in sequences; and identifying features in said sequence with said computer program.
- 29. A purified or isolated nucleic acid comprising a contiguous span of at least 12 nucleotides of the sequence of one of SEQ ID NOs: 24-73 or one of the sequences complementary thereto, wherein said contiguous span comprises at least 1 of the nucleotide positions of polynucleotides described in Table III.
- 30. A purified or isolated nucleic acid comprising a contiguous span of at least 12 nucleotides of the sequence of one of the polynucleotides described in Table III or one of the sequences complementary thereto.
RELATED APPLICATION
[0001] This application is a divisional of U.S. application Ser. No. 09/599,360, filed Jun. 21, 2000, pending, which is a continuation-in-part of U.S. application Ser. No. 09/469,099 filed Dec. 21, 1999, and claims priority from U.S. Provisional Patent Application Serial No. 60/113,686, filed Dec. 22, 1998, and U.S. Provisional Patent Application Serial No. 60/141,032, filed Jun. 25, 1999, the disclosures of which are incorporated herein by reference in their entireties (including all references, figures, sequences, and formulae).
Provisional Applications (2)
|
Number |
Date |
Country |
|
60113686 |
Dec 1998 |
US |
|
60141032 |
Jun 1999 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09599360 |
Jun 2000 |
US |
Child |
10315664 |
Dec 2002 |
US |
Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
09469099 |
Dec 1999 |
US |
Child |
09599360 |
Jun 2000 |
US |