Claims
- 1. A composition which comprises a soluble c-kit ligand protein, and one or more hematopoietic factors, the amount of each in the composition being such that the composition is effective to expand hematopoietic stem cells.
- 2. The composition of claim 1, wherein the hematopoietic factor is interleukin 1 (IL-1).
- 3. The composition of claim 1, wherein the hematopoietic factor is interleukin 3 (IL-3).
- 4. The composition of claim 1, wherein the hematopoietic factor is interleukin 6 (IL-6).
- 5. The composition of claim 1, wherein the hematopoietic factor is granulocyte macrophage-colony stimulating factor (GM-CSF).
- 6. The composition of claim 1, wherein the hematopoietic factor is granulocyte--colony stimulating factor (G-CSF).
- 7. The composition of claim 1, wherein the hematopoietic factor is erythropoietin.
- 8. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-l) and interleukin 3 (IL-3).
- 9. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1) and interleukin 6 (IL-6).
- 10. The composition of claim 1, wherein the hematopoietic factors are interleukin 3 (IL-3) and interleukin 6 (IL-6).
- 11. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1) and granulocyte macrophage-colony stimulating factor (GM-CSF).
- 12. The composition of claim 1, wherein the hematopoietic factors are interleukin 6 (IL-6) and granulocyte macrophage-colony stimulating factor (GM-CSF).
- 13. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1) and granulocyte-colony stimulating factor (G-CSF).
- 14. The composition of claim 1, wherein the hematopoietic factors are interleukin 6 (IL-6) and granulocyte-colony stimulating factor (G-CSF).
- 15. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1), interleukin 6 (IL-6), and granulocyte macrophage-colony stimulating factor (GM-CSF).
- 16. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1), interleukin 6 (IL-6), and granulocyte-colony stimulating factor (G-CSF).
- 17. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1), interleukin 3 (IL-3), and interleukin 6 (IL-6).
- 18. The composition of claim 1, wherein the hematopoietic factors are interleukin 1 (IL-1), interleukin 3 (IL-3), interleukin 6 (IL-6), and granulocyte-colony stimulating factor (G-CSF).
Parent Case Info
This invention is a continuation of U.S. Ser. No. 07/873,962, filed Apr. 23, 1992, now abandoned, which is a continuation-in-part application of PCT/US91/06130, filed Aug. 27, 1991, which is a continuation-in-part of U.S. Ser. No. 594,306, filed Oct. 5, 1990, which in turn is a continuation-in-part of U.S. Ser. No. 573,483, filed Aug. 27, 1990, now abandoned, the contents of all three are hereby incorporated by reference into the present application.
Government Interests
The invention described herein was made in the course of work under Grant No. RO1-CA 32926 and ACS MV246D from the National Institute of Health and American Cancer Society, respectively. The United States Government has certain rights in this invention.
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Continuations (1)
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Apr 1992 |
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Continuation in Parts (2)
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594306 |
Oct 1990 |
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573483 |
Aug 1990 |
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