The present invention relates to a depth of interaction detector with uniform pulse-height, which is a scintillation radiation detector having a function of detecting radiation depth of interaction and a function of selecting radiation absorption energy imparted thereto.
Conventionally, there has been known a three-dimensional depth of interaction detector (see, for instance, Document 1 as will be given later) as a depth of interaction detector, which is a scintillation radiation detector having a function of detecting radiation depth of interaction and a function of selecting radiation absorption energy imparted thereto. In this detector, however, the conditions set for absorbed radiation energy may vary depending on every scintillation cell and they must thus be selected independently or individually. For this reason, this detector never has a structure in which radiation energies are selected through a circuit on the basis of the same selection conditions or the same signal-processing circuit. This not only complicates the structure of such a signal-processing circuit for a multi-layer scintillation block obtained by stacking up scintillator cells, but also suffers from a problem in that images thus obtained are non-uniform because the energy resolution capacity of the scintillator cells differ from one another. In other words, there is observed, for scintillator cells located far away from a light-receiving element, a decrease of the sum of output signals due to such stacking up of the scintillator layers and accordingly, the overall depth of interaction-detecting characteristics and energy-resolving characteristics of the device would be damaged.
To obtain the same pulse-height for the sum of signals irrespective of which scintillator cell indeed emits light rays, there has been used an optical attenuation technique such as the replacement of a part of the light-reflecting material surrounding cells located in the proximity to the light-receiving element with a light-absorbing material (see, for instance, Document 3 as will be given later). However, this method suffers from a problem such that all of the abilities of resolving energy, position (depth of interaction) and time are deteriorated because of the reduction of the quantity of light capable of being utilized by the light-receiving element.
Accordingly, it is an object of the present invention to provide a depth of interaction detector with uniform pulse-height as a radiation detector, which receives light rays on the end of a scintillator having a long and narrow shape and which is improved in the uniformity of energy information and position or depth of interaction information generated due to the dependence of the quantity of light received upon the distance between the light-emitting position (a light-emitting scintillator cell) and the light-receiving element.
It is a further object of the present invention to provide a depth of interaction detector with uniform pulse-height as a radiation detector, in which the difference in light collection efficiency between scintillator cells is reduced and the optical output of the light-receiving element is high even when radiation is absorbed by and emitted from a scintillator layer positioned above the scintillator layer optically coupled to the light-receiving element.
It is a still further object of the present invention to provide a depth of interaction detector with uniform pulse-height having a three-dimensional depth of interaction-detecting function and an energy information acquisition function independent of which scintillator cell practically emits light rays. The detector is excellent in the energy resolution capacity, it can provide, even when radiation is absorbed by and emitted from a scintillator layer positioned above the scintillator layer optically coupled to the light-receiving element, precise detected information with respect to the energy-position (or depth of interaction) with an accuracy identical to that observed for the lower part of the scintillator layers of the detector and it thus permits any compact arrangement of scintillator cells along the periphery of a torus.
It is a still another object of the present invention to provide a depth of interaction detector with uniform pulse-height, which is never accompanied by any deterioration of abilities of resolving energy, position (or depth of interaction) and time, unlike the optical attenuation technique such as those conventionally used.
According to the present invention, there have thus been provided a depth of interaction detector with uniform pulse-height as will be specified below:
1. A depth of interaction detector with uniform pulse-height, which comprises a multi-layer scintillator obtained by coupling at least two scintillator cells in a planar shape (or on a plane) and then stacking the planar coupled scintillator cells, in layers, up to at least two stages and a light-receiving element connected to the bottom face of each scintillator cell of this multi-layer scintillator, wherein the detector is provided with a means for discriminating the position of a scintillator cell, which receives radiant rays and emits light rays and a means for making, uniform, the quantity of the light emitted from each scintillator cell and received by the light-receiving element.
2. The depth of interaction detector with uniform pulse-height as set forth in the foregoing item 1, wherein the multi-layer scintillator is one obtained by coupling a plurality of scintillator cells arranged in a matrix of 2 to 3 columns and 2 to 3 rows on a plane and then stacking the resulting planar coupled scintillator cells, in layers, up to 3 to 5 stages.
3. The depth of interaction detector with uniform pulse-height as set forth in the foregoing item 1, wherein the multi-layer scintillator is one obtained by coupling 4 scintillator cells arranged in 2 columns and 2 rows on a plane and then stacking the resulting planar coupled scintillator cells in layers of four stages.
4. The depth of interaction detector with uniform pulse-height as set forth in any one of the foregoing items 1 to 3, wherein the means for discriminating the position of the scintillator cell, which absorbs radiant rays and emits light rays is one for discriminating or identifying the pulse shape of the light emitted from scintillator layers in the proximity to one another.
5. The depth of interaction detector with uniform pulse-height as set forth in the foregoing item 4, wherein the means for discriminating or identifying the pulse shape of the light emitted from scintillator layers in the proximity to one another is one which makes use of the difference in the attenuation-time coefficient for the emitted light.
6. The depth of interaction detector with uniform pulse-height as set forth in the foregoing item 5, wherein the difference in the attenuation-time coefficient is not less than 5 ns, preferably not less than 10 ns and more preferably not less than 20 ns.
7. The depth of interaction detector with uniform pulse-height as set forth in the foregoing item 6, wherein the scintillator is a cerium-doped Gd2SiO5 single crystal.
8. The depth of interaction detector with uniform pulse-height as set forth in any one of the foregoing items 1 to 7, wherein the means for making, uniform, the quantity of the light emitted from each scintillator cell and received by the light-receiving element is the roughened surfaces of the scintillator cells in the scintillator layer in the proximity to the uppermost scintillator layer; the mirror-finished surfaces of the scintillator cells in a scintillator layer other than those in the proximity to the uppermost scintillator layer; the disposition of a light-reflecting material between the scintillator cells in a scintillator layer other than the uppermost scintillator layer and the scintillator layers in the proximity thereto; and the disposition of a light-reflecting material on the outer surfaces of a scintillator cell free of any neighboring scintillator cell.
9. The depth of interaction detector with uniform pulse-height as set forth in any one of the foregoing items 1 to 8, wherein the boundaries between each pair of neighboring scintillator layers and the boundaries between each light-receiving element and the corresponding neighboring scintillator layers are filled with a light-permeable material transparent to the light rays emitted from the scintillator cell.
10. The depth of interaction detector with uniform pulse-height as set forth in any one of the foregoing items 1 to 9, wherein it comprises a multi-layer scintillator obtained by coupling 4 scintillator cells arranged in a matrix of 2 columns and 2 rows on a plane and then stacking the resulting planar coupled scintillator cells in layers of four stages and a light-receiving element connected to the bottom face of each scintillator cell of this multi-layer scintillator, wherein the scintillator is a cerium-doped Gd2SiO5 single crystal; wherein the doses of the cerium in the cerium-doped first and third scintillator layers are higher than those observed in the cerium-doped second and fourth scintillator layers and wherein the difference between the attenuation-time coefficients of these two kinds of scintillator layers is not less than 10 ns.
11. The depth of interaction detector with uniform pulse-height as set forth in the foregoing item 10, wherein the surfaces of the scintillator cells in the first, second and fourth scintillator layers are mirror-finished; the surface of the scintillator cells in the third scintillator layer are surface-roughened; light-reflecting materials are interposed between the scintillator cells in the first and second scintillator layers and on the outer surfaces of the scintillator cells; the boundaries between each neighboring scintillator layers and the boundaries between the light-receiving elements and the first scintillator layer are filled with silicone oil; the boundaries between the scintillator cells in the third and fourth scintillator layers are filled with air; the scintillator cells in the first and third scintillator layers are Gd2SiO5 single crystals each doped with 1.5 mole % of cerium; and the scintillator cells in the second and fourth scintillator layers are Gd2SiO5 single crystals each doped with 0.5 mole % of cerium.
According to the present invention, a depth of interaction detector with uniform pulse-height excellent in the abilities of resolving energy, position (or depth of interaction) and time can thus be provided if a multi-layer scintillator is formed by coupling at least two, preferably at least four scintillator cells on a plane and then stacking a plurality of such planar, coupled scintillator cells in layers of at least two stages, preferably 3 to 5 stages and most preferably four stages; at least two light-receiving elements or those capable of resolving the depth of interaction are optically connected to the resulting multi-layer scintillator; the interstices (or boundaries) between every paired neighboring scintillator cells are filled with at least one member selected from the group consisting of air, light-reflecting materials, light-permeable materials and the same materials used for forming the foregoing scintillator; the optical surface conditions (mirror-finished or roughened surface) for each scintillator cell and the combination of such light-reflecting and light-permeable materials are optimized, to thus identify each specific scintillator cell, which detects radiant rays and to discriminate the radiation energy on the basis of the signals output from the light-receiving elements.
As the means for discriminating the position of a scintillator cell, which absorbs radiant rays and emits light rays used in the depth of interaction detector with uniform pulse-height according to the present invention, there can be listed, for instance, a means for discriminating the waveforms of the light rays emitted from the neighboring scintillator layers. Specific examples of such means for discriminating the waveforms of the light rays emitted from the neighboring scintillator layers include those, which make use of the difference between the attenuation-time coefficients for the emitted light rays. The difference between the attenuation-time coefficients is preferably not less than 5 ns, more preferably not less than 10 ns and most preferably not less than 15 ns.
The materials for the scintillator used in the depth of interaction detector according to the present invention are not restricted to specific ones inasmuch as they can absorb radiant rays and emit light rays, but specific examples thereof are cerium-doped GSO (Ce: Gd2SiO5), cerium-doped LSO (Ce: Lu2SiO5) and BGO (Bi4Ge3O12). However, the higher the fluorescent output of the scintillator material, the greater the depth of interaction-discrimination effect of the resulting detector and therefore, the scintillator materials used in the present invention are desirably those showing an output of not less than 50% higher than that observed for Bi4Ge3O12 and it is more desirable to use Ce: Gd2SiO5. The amount of cerium used for doping Ce: Gd2SiO5 preferably ranges from 0.1 to 5.0 mole % and is more preferably on the order of 0.5 to 1.5 mole %. The ability of discrimination between waveforms of neighboring two scintillator layers and hence the depth of interaction discrimination capacity can be improved if changing the fluorescent attenuation-time coefficient of the scintillator cell by adjusting the dose of cerium in the Ce: Gd2SiO5 single crystal. To this end, the difference in dose of cerium between the neighboring two scintillator layers is set at a level ranging from about 0.1 to 3.0 mole % to thus increase the difference between the attenuation-time coefficients to a level of not less than 5 ns, preferably not less than 10 ns and more preferably not less than 20 ns.
Each scintillator cell used herein is preferably one obtained by cutting a scintillator material (a single crystal) into a rectangular prism-like shape and the size thereof is suitably on the order of 1.0 to 10 mm×1.0 to 10 mm×10 to 50 mm.
As the means for making, uniform, the quantity of the light emitted from each scintillator cell and received by the light-receiving element, there may be listed, for instance, the roughened surfaces of the scintillator cells in a scintillator layer in the proximity to the uppermost scintillator layer; the mirror-finished surfaces of the scintillator cells in a scintillator layer other than those arranged in the proximity to the uppermost scintillator layer; the disposition of a light-reflecting material between the scintillator cells in a scintillator layer other than the uppermost scintillator layer and the scintillator layers in the proximity thereto; and the disposition of a light-reflecting material on the outer surfaces of a scintillator cell free of any neighboring scintillator cell.
Surfaces of a single crystal can be mirror-finished according to, for instance, a mechanical polishing method or a chemical polishing method.
Surfaces of a single crystal can be roughened by the use of, for instance, a cutting method or a coarse polishing method. The degree of surface-roughness suitably ranges from 346 nm (plane of cleavage) to 376 nm (plane of cleavage) as expressed in terms of the maximum height (Rmax).
In addition, examples of the light-reflecting materials usable herein are metal foils (such as an aluminum foil), polymer films (such as a polytetrafluoroethylene film) and inorganic powdery substances. The thickness of these light-reflecting materials interposed between scintillator cells in general ranges from 10 to 500 μm and preferably 30 to 200 μm.
In the depth of interaction detector according to the present invention, it is desirable that the interstices between each pair of neighboring scintillator layers and each light-receiving element and the corresponding neighboring scintillator layer are filled with a light-permeable material transparent to the light rays emitted from the scintillator cell in order to make, uniform, the total quantity of light received by the light-receiving elements. Examples of such light-permeable materials transparent to the light rays emitted from the scintillator cell include silicone oil, air and transparent adhesives, with the silicone oil being preferred.
As has been discussed above in detail, each scintillator cell within a scintillator unit in the depth of interaction detector of the present invention can be controlled in its fluorescent attenuation-time coefficient by the adjustment of the content of impurities or the composition thereof and may be subjected to either a surface-roughening or mirror-finishing treatment arbitrarily selected. Moreover, an optically discrete layer may be formed as a boundary layer between cells and either a light-reflecting material or a light-permeable material (an optical coupling agent) transparent to the emitted light may be inserted into the interstices between the layers. As is disclosed in Japanese Un-Examined Patent Publication Hei 11-142523 in detail, the light rays generated in a certain scintillator cell are partially distributed to the neighboring scintillator cells in a certain rate through the boundary layers. The dispensed light rays thus received by neighboring scintillator cells are likewise distributed to the scintillator cells adjacent to the former ones in a certain rate and the same process described above successively take place between scintillator cells present in a scintillator unit and the light rays finally arrive at each light-receiving element coupled to the unit at one end thereof.
The quantity of light received by each light-receiving element is dependent upon the light-sharing rate observed between each pair of scintillator cells present in the foregoing scintillator unit and accordingly, if variously devising such light-sharing rates to thus variously combine the quantities of light rays received by each light-receiving element, it becomes possible to identify the scintillator cell just emitting light rays among those present in a scintillator unit and to thus measure the depth of interaction in the depth of interaction direction in the scintillator unit. At the same time, the optimization of the combination of the optical surface of a scintillator cell, light-reflecting and light-permeable materials to be used would permit the production of a depth of interaction detector with uniform pulse-height in which the total quantity of light rays received by all of the light-receiving elements is identical irrespective of which cell practically emits light rays, while allowing the discrimination of the depth of interaction.
Moreover, it is desirable in the present invention to use a highly sensitive light-receiving element such as one having a sensitivity of about 30% and one having a high light collection efficiency, in order to improve the discrimination of the depth of interaction.
The present invention will hereunder be described in more detail with reference to the accompanying drawings.
Moreover, if all of the scintillator cells (GSO single crystals) have roughened optical surfaces, the total quantity of light emitted by each scintillator cell and received by the corresponding light-receiving element is greatly different from cell to cell, while if all of the scintillator cells (GSO single crystals) have the same mirror-finished optical surfaces, regions specified by circles in the two-dimensional distribution showing the light-sharing rates are superimposed on one another.
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The three-dimensional depth of interaction detector according to the present invention can provide precise detected information even when radiation is absorbed by and emitted from a scintillator layer positioned above the scintillator layer optically coupled to the light-receiving element, it permits the production of a depth of interaction detector having a three-dimensional depth of interaction-detecting function and it can provide the same total output signal, which is independent of the position or a specific scintillator cell practically emitting light if the radiation energy is identical. Since the detector never requires the use of any light-absorbing material unlike the conventional techniques, excellent abilities of resolving energy, position (or depth of interaction) and time of the detector would thus be ensured. The incorporation of the depth of interaction detector with uniform pulse height according to the present invention into a positron emission tomography (PET) would permit the analysis of the radiation energy information using only a single pulse height-analyzing circuit.
In the foregoing embodiment of the present invention, only Ce: Gd2SiO5 single crystal is used as the material for the scintillator, but the scintillator material usable in the hakama-shaped (Japanese skirt-shaped) depth of interaction detector according to the present invention is not restricted to Ce: Gd2SiO5 at all. In this respect, however, the higher the fluorescent output of the scintillator material used in the present invention, the better the effect attained. Therefore, it is desirable that the scintillator material is one having an output of not less than 50% higher than that observed for Bi4Ge3O12 and it is more desirable to use Ce: Gd2SiO5.
Moreover, the foregoing embodiment of the present invention simply utilizes one or two kinds of scintillators having different fluorescent attenuation-times as the scintillator materials, but the present invention likewise includes an embodiment, which comprises a combination of at least three kinds of different scintillators. The use of scintillator materials having different fluorescent attenuation-times would permit the discrimination of the difference in fluorescent attenuation time on the basis of the waveform-discrimination. The present invention, therefore, permits the development of a depth of interaction detector in which the depth of interaction can be detected on the basis of the waveform-discrimination of output signals.
Preferred embodiments of the present invention will be described below:
1. A depth of interaction detector having a desired shape, which permits the collection of information on the detected depth of interaction and the discrimination of the radiation energy absorbed by the detector through the comparing and summing operations of a plurality of output signals.
2. A depth of interaction detector characterized in that at least two scintillator cells are coupled on a plane, that the planar, coupled scintillator cells are put in layers of at least two stages to form a multi-layer scintillator, that the boundaries between the scintillator cells are constituted by at least one member selected from the group consisting of air, light-reflecting materials, light-permeable materials and the foregoing materials for the scintillator, that the bottom face of the multi-layer scintillator is connected to at least two light-receiving elements or at least one light-receiving element capable of resolving position, and that the scintillator cell just emitting radiant rays is detected or identified and the radiation energy absorbed by the scintillator cells are discriminated on the basis of the signals output from the foregoing light-receiving elements.
3. The depth of interaction detector according to the foregoing embodiment 2, wherein the multi-layer scintillator is obtained using a plurality of scintillators having the same characteristic properties or having different fluorescent attenuation-time coefficients.
4. The depth of interaction detector according to the foregoing embodiment 2, wherein the multi-layer scintillator is obtained using a plurality of scintillators having different surface optical conditions.
5. The depth of interaction detector according to the foregoing embodiment 2, wherein the multi-layer scintillator comprises boundaries between the scintillator cells constituted by different layer groups of light-reflecting materials or light-permeable materials or air.
6. The depth of interaction detector according to the foregoing embodiment 2, wherein each layer group constituting the multi-layer scintillator comprises a plurality of scintillators having different optical surfaces.
7. The depth of interaction detector according to any one of the foregoing embodiments 2 to 6, wherein the scintillator cell just emitting light is identified on the basis of the ratios of the magnitudes of signals output from the light-receiving elements.
8. The depth of interaction detector according to any one of the foregoing embodiments 2 to 6, wherein the radiation energy detected by the scintillator cell is discriminated by the pulse-height discrimination on the basis of the summation of the signals output from the light-receiving elements.
9. The depth of interaction detector according to any one of the foregoing embodiments 2 to 6, wherein the scintillator cell just emitting light and the radiation energy absorbed by the scintillator cell are identified on the basis of the ratios of the magnitudes of signals output from the light-receiving elements and by the pulse-height discrimination on the basis of the summation of the signals output from the light-receiving elements.
10. The depth of interaction detector according to any one of the foregoing embodiments 2 to 9, wherein each scintillator cell has a rectangular prism-like shape.
11. The depth of interaction detector according to any one of the foregoing embodiments 2 to 10, wherein the quantity of light energy absorbed by the scintillator cell, which detects the radiation, can be subjected to output pulse-height discrimination under the same conditions irrespective of the identification of the light-emitting scintillator cell.
Number | Date | Country | Kind |
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2002-300125 | Oct 2002 | JP | national |