Claims
- 1. A compound of the formula: ##STR7## wherein: X represents an atom of chlorine, bromine, iodine or an alkyl group having 1 to 4 carbon atoms;
- R.sup.1 and R.sup.2, equal or different from each other, represent a hydrogen atom or an alkyl group or a hydroxyalkyl group, said groups having 1 to 6 carbon atoms;
- R represents a group selected from: ##STR8## wherein: R.sup.3 represents a hydrogen atom or an alkyl group,
- R.sup.4 and R.sup.5, equal or different from each other, represent a hydrogen atom or an alkyl, an hydroxyalkyl, mercaptoalkyl, alkylphenyl, or phenyl group, wherein the alkyl groups have up to 6 carbon atoms and each phenyl group may have an OH substituent and
- Z represents an alkoxy group having 1 to 6 carbon atoms; and
- --O--CH.sub.2 --COZ
- wherein Z has the meaning given above;
- or a pharmaceutically acceptable salt of said compound.
- 2. The compound of claim 1 which is the methyl ester of N-2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl aminoacetic acid.
- 3. The compound of claim 1 which is N-(2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl)-DL-2-amino-2 methyl ethyl acetate.
- 4. The compound of claim 1 which is N-(2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl)-N-methyl-2-amino ethyl acetate.
- 5. The compound of claim 1 which is 2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl ethyl oxyacetate.
- 6. The compound of claim 1 which is N-(2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl)-L-2-amino-2-p-hydroxyphenylmethyl ethyl acetate.
- 7. The compound of claim 1 which is N-(2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl)-DL-2-amino-2-benzyl methyl acetate.
- 8. The compound of claim 1 which is N-(2-(4-(4-chlorobenzoyl)-phenoxy)-2-methyl propanoyl)-L-2-amino-2-hydroxymethyl methyl acetate.
- 9. A pharmaceutical preparation useful in the therapy of hyperlipaemia and of hypercholesterolemia, characterized in that it contains a hypolipaemic or hypocholesterolemic effective dose of at least one of the compounds of claim 1 associated or combined with one or more usual excipients or solvents.
Priority Claims (2)
Number |
Date |
Country |
Kind |
3426 A/78 |
May 1978 |
ITX |
|
3630 A/78 |
Dec 1978 |
ITX |
|
Parent Case Info
This is a division of application Ser. No. 123,454 filed Feb. 21, 1980 which in turn is a continuation of application Ser. No. 29,006 filed Apr. 11, 1979, now abandoned.
US Referenced Citations (7)
Divisions (1)
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Number |
Date |
Country |
Parent |
123454 |
Feb 1980 |
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Continuations (1)
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Number |
Date |
Country |
Parent |
29006 |
Apr 1979 |
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