In laser-assisted ophthalmic surgery, the refractive properties of an eye of a patient may be altered, for the purpose of correcting vision defects (e.g. hyperopia, myopia, astigmatism), by removal of corneal tissue with the aim to reshape the anterior surface of the cornea of the eye. One method to remove corneal tissue is by laser ablation, another method is by cutting out a volume of corneal tissue from the cornea using a cutting laser. Laser ablation is used, for example, in a procedure known as laser in-situ keratomileusis (LASIK). A cutting laser is used, for example, in a procedure named intracorneal lenticule extraction. In this procedure, a lens-shaped volume of corneal tissue (i.e. a lenticule) is cut away from surrounding tissue within the cornea. The lenticule is then removed through a channel leading to the outer surface of the eye.
Conventional ablating laser systems have a built-in eye-tracker to track eye motion during ablation and align the laser beam with the pupil center or another reference feature of the eye. Some eye-trackers offer a 6-dimensional tracking capability, i.e. they can track movements of the eye not only in three mutually orthogonal translational directions but additionally movements about three mutually orthogonal rotational axes. Conventional cutting laser systems used in ophthalmic surgery, conversely, require that the eye be fixated with respect to the laser system during laser operation using a suitable interface device (patient adapter), so that eye movement cannot occur during the laser treatment. It is for this reason that conventional cutting laser systems typically have no eye-tracking functionality.
An exemplary conventional patient adapter includes a suction ring and a coupling cone. The suction ring is placed onto the eye and fixed thereto by suction force. The coupling cone is mounted to the cutting laser system and has a contact member providing a contact surface for the eye. After the suction ring has been placed onto the eye, the coupling cone is lowered into the suction ring until the contact surface comes into contact with the outer surface of the eye. Depending on the shape of the contact surface, the eye may be deformed (e.g., levelled in the case of a plane contact surface) as a result of the contact surface being pushed against the eye.
Before the suction ring is placed onto the eye, the patient may be asked to stare with his eye to be treated at a fixed (e.g., red or green) light point created by the laser system. This light point serves as a means to ensure proper alignment of the visual axis of the eye with the laser system. The cutting pattern to be created in the eye is usually determined/calculated with respect to the pupil center as a reference point. But as soon as the suction ring has been placed onto the eye and the coupling cone has been coupled with the suction ring, the position of the eye's pupil center with respect to the laser system is invariably fixed. It is therefore important for the surgeon to position the suction ring on the eye as precisely as possible.
Conventional cutting laser systems offer the possibility for the surgeon to watch through an operating microscope the eye after its coupling to the laser system and during treatment. With some of these systems it is possible to shift the cutting pattern laterally in a coordinate system of the laser system with respect to the eye (i.e. in a plane orthogonal to the direction of beam emission from the laser system), based on the surgeon's observation of the eye through the operating microscope. For example, if the surgeon finds from his observation of the eye that the pupil is not properly centered with respect to the center of the suction ring (or with respect to a pair of cross hairs overlaid on the image of the eye that is displayed to the surgeon), he may manually steer the cutting pattern laterally until it has a desired position with respect to the pupil of the patient's eye.
The cutting pattern is oftentimes determined based on diagnostic data acquired in an upright position of the head of patient (e.g., while the patient is sitting on a chair). The laser treatment itself, conversely, is usually performed with the patient lying on a bed. It has been observed that the eye of a patient may undergo torsional movement about an axis intersecting the pupil during a change of the patient from the upright position to a lying position. For a cutting pattern that is rotationally symmetrical such torsion of the eye may be irrelevant. However, where the cutting pattern is rotationally non-symmetrical, it may be necessary to torsionally adjust the cutting pattern before the laser treatment is started.
Torsion compensation may generally include identifying a location of one or more features of an eye of a patient, these features including at least one of an anatomical structure of the eye (e.g. a blood vessel, an iris structure, etc.) and a paint mark applied to the eye.
One object of embodiments of the present invention is to provide a marker device that offers good positional reproducibility for applying paint marks on an eye.
In one aspect, embodiments of the present invention provide a marker device for producing paint marks on an eye. The marker device comprises a handling unit and a marker unit coupled to the handling unit for rotation with respect to the handling unit about a rotational axis. The marker unit includes a plurality of at least two spaced apart marking surfaces and has a rotationally asymmetric distribution of weight with respect to the rotational axis. The coupling between the handling unit and the marker unit permits the marker unit to rotate, due to gravity, relative to the handling unit into an equilibrium position.
According to certain embodiments, the marker unit includes at least one pair of marking surfaces disposed diametrically opposite to each other with respect to the rotational axis. In these embodiments, a pair of marking surfaces may be arranged opposite each other along a horizontal line intersecting the rotational axis when the marker unit is in the equilibrium position. Alternatively or additionally, a pair of marking surfaces may be arranged opposite each other along a vertical line intersecting the rotational axis when the marker unit is in the equilibrium position.
According to certain embodiments, the marker unit includes at least three, and for example a total of four, marking surfaces disposed at equal angular distances about the rotational axis.
According to certain embodiments, at least one, and for example each, of the plurality of marking surfaces has a concave shape. The concave shape may be selected to substantially match with the curvature of the outer surface of a human eye.
According to certain embodiments, the marker unit includes a main body and a plurality of marking protrusions projecting from the main body, wherein a marking surface is disposed at each of said marking protrusions.
Each of the marking protrusions may have a shape of a rib, the rib extending in a rib longitudinal direction and a having a breast surface forming one of the marking surfaces. The rib longitudinal direction of each of the marking protrusions may intersect with the rotational axis. Each of the marking protrusions may have a length from about 2 mm to about 4 mm in the rib longitudinal direction in the region of the breast surface.
According to certain embodiments, the main body has a design of an annular body.
According to certain embodiments, a distance between an edge of each marking surface, the edge facing the rotational axis, and the rotational axis is from about 3 mm to about 4.5 mm or from about 3.5 mm to about 4 mm when viewed in a plane orthogonal to the rotational axis.
According to certain embodiments, the handling unit includes a handling rod which, when viewed in a plane orthogonal to the rotational axis, projects radially from the marker unit. The handling rod may have a rod longitudinal direction extending at an acute angle of at most 30 degrees or at most 20 degrees or at most 10 degrees with respect to a plane orthogonal to the rotational axis. A length of the handling rod may be at least the size of a human palm.
According to another aspect, embodiments of the present invention provide a method for producing paint marks on an eye, the method comprising: providing a marker device as defined above; applying paint to one or more of the plurality of marking surfaces of the marker device; holding the marker device in a spatial orientation permitting the marker unit to rotate, due to gravity, relative to the handling unit into an equilibrium position; and contacting the eye with the marking surfaces in the equilibrium position of the marker unit to thereby transfer paint from the marking device to the eye.
Further elements, aspects and objects of the present invention may be taken from the subsequent discussion of specific embodiments shown in the accompanying drawings, in which:
Reference is initially made to
The handling unit 12 may be formed from metal or from plastic or any other suitable material. It is possible that the handling unit 12 is integrally formed from a single material. Alternatively, the handling rod 18 may be formed from a different material than the rest of the handling unit 12. According to the examples shown in
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According to another embodiment of the invention as shown in
The rotationally asymmetric distribution of weight may additionally or alternatively be obtained by applying an additional weight 22 to the marker unit 14 by fixation means, as schematically shown in
Both the embodiments in
When the user holds the marker device 10 in one of his hands in a predetermined spatial orientation, the coupling between the handling unit 12 and the marker unit 14 permits the marker unit 14 to rotate, relative to the handling unit 12, into an equilibrium position. This rotation is merely induced by gravity. Besides the rotationally asymmetric distribution of weight of the marker unit 14, another prerequisite to provide this function is that the coupling is smooth. The rotationally asymmetric distribution of weight results in a torque when the marker unit 14 is in a position (hereinafter referred to as starting position) that does not correspond to the equilibrium position. For all possible starting positions of the marker unit 14, said torque has to overcome static friction of the coupling so that the marker unit 14 can move into the equilibrium position. The coupling may be continuously variable so that the static friction is independent from the starting position of the marker unit 14. The coupling may comprise but is not limited to a bearing such as an anti-friction bearing.
In the example embodiments shown in
In an embodiment including two marking surfaces 16, the marking surfaces 16 may be disposed diametrically opposite to each other with respect to the rotational axis. The two marking surfaces 16 may be disposed on a common horizontal line that intersects the rotational axis when the marker unit 14 is in the equilibrium position.
In an embodiment including three marking surfaces 16, two of the marking surfaces 16 may be disposed diametrically opposite to each other with respect to the rotational axis. The third marking surface 16 may be disposed at an equal angular distance about the rotational axis with respect to the other two marking surfaces 16. The two of the marking surfaces 16 that are disposed diametrically opposite to each other may be disposed on a common horizontal line that intersects the rotational axis when the marker unit 14 is in the equilibrium position.
In an embodiment including more than four marking surfaces 16, the marking surfaces 16 may be disposed at equal angular distances about the rotational axis. Two of the marking surfaces 16 may be disposed on a common horizontal line that intersects the rotational axis when the marker unit 14 is in the equilibrium position. The more marking surfaces 16 the marker device 10 includes the more paint marks may be created on an eye. A higher amount of created paint marks may be advantageous for relocating the paint marks for torsion correction.
In the example shown in
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Materials used for manufacturing the marker device 10 may be biocompatible and applicable in a surgical environment. The marking surfaces 16 may be manufactured from a flexible material to prevent the eye from being injured when paint marks are created. The marking surfaces 16 may further be adapted to easily absorb and release the paint applied thereto.
In the examples shown in
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A second step includes applying paint to two or more of the marking surfaces 16 of the marker device 10. As indicated in the example in
A third step of the method includes holding the marker device 10 in a spatial orientation such that the marker unit 14 rotates, due to gravity, into an equilibrium position relative to the handling unit 12. It is not limiting for the functionality of the marker device 10 whether the user holds the marker device 10 in its left hand or in its right hand. Also, different users may hold the handling rod 18 of the marker device 10 at different positions within a plane transverse to the rotational axis in order to conveniently use the marker device 10. The equilibrium position may be reached when two of the marking surfaces 16 are disposed on a common horizontal line that intersects the rotational axis, as for example shown in
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The laser system 34 comprises a laser source 36 configured to generate a laser beam 38 and further includes a xyz-scanning device 40 to deflect a focus of the laser beam 38 both in a direction of beam propagation and in a plane transverse to the direction of beam propagation. In line with usual notation in the art, the direction of beam propagation may be referred to as a z-direction and a plane orthogonal to the z-direction may be referred to as a xy-plane. The laser source 36 may produce pulsed laser radiation with a pulse duration in the nanosecond, picosecond, femtosecond or attosecond range. The laser radiation emitted from the laser system 34 has radiation properties that ensure the generation of a laser-induced optical breakdown (LIOB) in tissue of the eye following application of a single pulse or a group of pulses of the radiation. The laser beam 38 is focused by a focusing unit 42 and applied to the eye 30 of the patient. During surgery, a control unit 44 controls the laser source 36 and the scanning device 40 in accordance with a control program stored in a memory 46 of the laser system 34. The control program represents a cutting pattern which is to be realized in the eye through generation of a series of photodisruptions (each based on a LIOB). The cutting pattern is defined with regard to a xyz-coordinate system of the laser system 34 and is usually determined based on diagnostic data acquired while the patient is in an upright position. Since the patient's eye may undergo torsion when the patient changes his position from upright to lying, an angular correction (torsion correction) may have to be applied to the cutting pattern in the xyz-coordinate system of the laser system 34 before the laser treatment is started.
A patient interface 47 serves to couple the eye 30 to the laser system 34. The patient interface 47 may include, in a manner conventionally known per se, a suction ring to be placed onto the eye 30 and a coupling cone detachably mounted to a housing portion of the laser system 34. The coupling cone can be lowered into the suction ring and can be held together with the suction ring by suction force. The coupling cone is provided with a contact element having a contact surface for the eye 30. In a state in which the eye 30 is coupled to the laser system 34 via the patient interface, the anterior surface of the eye 30 is in contact with the contact surface of the contact element and may, for example, be flattened as a result of such contact.
The laser system 34 further comprises an operating microscope 48 and an overlay unit 49. The operating microscope 48 permits the surgeon to observe the eye through the focusing unit 42 when the eye is coupled to the laser system 34. An example image of the eye 30 is shown in the lower part of
Therefore, a second picture is superposed to the live picture by an overlay unit 49 of the laser system 34. The second picture contains elements (e.g. certain symbols) to simplify orientation for the correction process. It is therefore possible for the surgeon to readily identify a torsional movement of the eye 30 of a patient with respect to the xyz-plane of the laser system 34 that occurred when the patient moved into the lying position for surgery.
Alternatively and as shown in the examples in
In another embodiment of the invention, the control unit 44 may automatically detect the created paint marks 32 on the eye 30 of the patient by image processing means. Said image processing means may or may not include the overlay unit 49. The laser system 34 then provides the surgeon with a suggestion for the lateral correction and for torsion correction. The surgeon may adapt, by operating means, the suggested shift in coordinates and save the shift in coordinates in the memory 46 of the laser system 34 for a subsequent correction of the cutting pattern. Alternatively, it may be envisaged by the invention that the laser system directly applies the resulting shift in coordinates to the cutting pattern.
Filing Document | Filing Date | Country | Kind |
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PCT/EP2015/075147 | 10/29/2015 | WO | 00 |