Claims
- 1. An isolated E-rotamer of 7-acylamino-3-hydroxy-cephem-4-carboxylate-1-oxide compound having the formula: ##STR4## wherein R is aryl, aralkyl, or aryloxyalkyl, and R.sup.1 is linear or branched chain alkyl, aryl, aralkyl, aryloxyalkyl, or alkoxyalkyl.
- 2. The compound of claim 1 wherein R is phenyl lower alkyl, phenoxy lower alkyl, or thienyl lower alkyl.
- 3. The compound of claim 1 wherein R.sup.1 is benzyl, p-methoxybenzyl, p-nitrobenzyl, or diphenyl methyl.
- 4. The compound of claim 1 wherein R is phenoxymethyl and R.sup.1 is p-nitrobenzyl.
- 5. The compound of claim 1 which is substantially pure.
- 6. A 7-acylamino-3-hydroxy-cephem-4-carboxylate-1-oxide compound, comprising an E-rotamer of said compound having the formula: ##STR5## and substantially no Z-rotamer, wherein R is aryl, aralkyl, or aryloxyalkyl, and R.sup.l is linear or branched chain alkyl, aryl, aralkyl, aryloxyalkyl, or alkoxyakyl.
- 7. The compound of claim 6 where in R is phenyl lower alkyl, phenoxy lower alkyl, or thienyl lower alkyl.
- 8. The compound of claim 6 wherein R.sup.1 is benzyl, p-methoxybenzyl, p-nitrobenzyl, or diphenyl methyl.
- 9. The compound of claim 6 wherein R is phenoxymethyl and R.sup.1 is p-nitrobenzyl.
- 10. The compound of claim 6 which is substantially pure E-rotamer.
Priority Claims (1)
Number |
Date |
Country |
Kind |
700/DEL/92 |
Aug 1992 |
INX |
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Parent Case Info
This is a divisional of application Ser. No. 08/019,269, filed Feb. 18, 1993 now U.S. Pat. No. 5,410,044.
US Referenced Citations (10)
Divisions (1)
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Number |
Date |
Country |
Parent |
19269 |
Feb 1993 |
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