Patent Application
20210386376
The present invention relates to an electric component of an interventional device, to an interventional device for at least partly insertion into a subject and to a method for manufacturing an electric component of an interventional device.
In interventional medical devices, electric components are provided, e.g. integrated in the distal end of a catheter or guidewire. As an example, an electric circuit of a sensor in the end portion may be arranged. Because such interventional devices are provided for insertion into a vessel structure of a subject, the dimensions of the integrated electric components should be small. For example, WO 2018/095991 A1 relates to electrical connections to miniature sensors. As a further example, WO 2015/077449 A1 relates to semiconductor sensor chips in catheters.
US 2014/0371744 A1 discloses an electronic circuit arrangement comprising: a substrate having a first surface and a second surface, an electronic circuit, an electrical connection part for providing an electrical connection to the electronic circuit and being arranged on the first surface, and at least one electrical wire. A through-hole extending from the first surface to the second surface is provided in the substrate, wherein the electrical wire is arranged through the through-hole, and connected to electrical connection part, such that the longitudinal axis of the end portion of the electrical wire is perpendicular to the first and second surfaces of the substrate.
EP 0081389 A2 discloses a device for electrically connecting a conductor to another conductor, comprising a dimensionally heat-stable polymeric layer having a window therein and a quantity of fusible electrically conductive solder disposed with respect to the window to allow it to flow through the window and to form a conductive connection between conductors positioned on opposite sides of the polymeric layer.
However, an increasing demand exists to further reduce the size of sensors e.g. for inserting a catheter distal end in smaller vessel structures.
There may thus be a need to provide further miniaturization of medical interventional devices.
The object of the present invention is solved by the subject-matter of the independent claims; further embodiments are incorporated in the dependent claims. It should be noted that the following described aspects of the invention apply also for the electric component of an interventional device, for the interventional device for at least partly insertion into a subject and for the method for manufacturing an electric component of an interventional device.
According to the present invention, an electric component of an interventional device is provided. The component comprises a flat carrier base, at least one electric circuit provided on a substrate and at least one electric wire connected to the electric circuit by a wire connection. The substrate is attached to a first side of the carrier base. For the wire connection, the carrier base is provided with at least one slit opening that is provided at least partly with a conductive edge portion, which edge portion is connected to the at least one electric circuit. The substrate is provided with at least one recess aligned with the location of the at least one slit opening in the carrier base. Further, an end portion of the wire is arranged in the at least one recess, and substantially parallel to the substrate. Furthermore, the end portion of the wire is conductively coupled to the conductive edge portion by soldering.
As a result, the size of the electric component is kept to a minimum and thus enables smaller sized distal ends of interventional devices.
According to an example, the substrate of the at least one electric circuit is attached to the carrier base on a first side and the at least one electric wire is connected to the carrier base also on the first side.
According to an example, the carrier base comprises a flexible layer and conductor paths attached to the flexible layer.
For example, a flexible carrier plate can be adjusted to different forms of an interventional device, e.g. due to guidewire bending.
According to an example, the substrate of the electric circuit is a rigid substrate made from silicon.
According to an example, the end portion of the wire is provided with a circumferentially enclosing electric insulation, which is removed in alignment with the respective slit opening on a side of the wire facing the slit opening.
According to an example, the at least one recess is arranged in line with, but displaced to the at least one slit opening. Further, the wire first extends through the recess and then reaches the slit opening. Still further, the wire is provided with a circumferential layer of electric insulation in a portion within the recess. Furthermore, the wire is mechanically coupled with an adhesive to edge portions of the substrate forming the recess.
According to an example, the at least one slit opening is arranged in line with the at least one recess, wherein the recess is having a longer extension than the slit opening such that a first part of the recess is provided with the slit opening in the carrier base and a second part is provided without a slit opening in the carrier base. Further, the wire is provided with an insulated section having a circumferential layer of electric insulation in a portion within the second part of the recess, in which insulated section the wire is mechanically coupled with an adhesive to edge portions of the substrate forming the recess. Still further, the wire is provided with a stripped end section without insulation in a portion within the first part of the recess, in which stripped end section the wire is connected by the soldering.
According to an example, the electric component relates to at least one of the group of a sensor, a measurement unit and an application unit for an interventional device.
According to the present invention, also an interventional device for at least partly insertion into a subject is provided. The device comprises an elongated main body structure and an electric component provided according to one of the preceding examples. The main body structure comprises a distal part, or distal end, for insertion into a subject, for example into vessels of a vascular structure. Further, the electric component is attached to the distal part of the main body structure.
According to the present invention, also a method for manufacturing an electric component of an interventional device is provided. The method comprises the following steps:
a) providing a flat carrier base with at least one electric circuit provided on a substrate, the substrate circuit being attached to the carrier base; wherein the carrier base is provided with at least one slit opening that is provided at least partly with a conductive edge portion, which edge portion is connected to the at least one electric circuit; and wherein the substrate is provided with at least one recess aligned with the location of the at least one slit opening in the carrier base;
b) providing at least one electric wire for connection with the electric circuit;
c) arranging an end portion of the at least one electric wire in the at least one recess; and
d) soldering the end portion of the wire to the conductive edge portion to conductively couple the end of the wire and the conductive edge portion.
According to an example, in step c), the end portion of the wire is provided with a circumferentially enclosing electric insulation. Further, before step d), the insulation is removed in alignment with the respective slit opening on a side of the wire facing the slit opening.
According to an aspect, an electric connection of an electrical circuit is provided with a cable connection that is connected by soldering via a slit opening in a carrier plate. The soldering is supplied so-to-speak from the other side. An end portion of the cable runs parallel to the substrate in a recess of the substrate provided for the electric circuit.
These and other aspects of the present invention will become apparent from and be elucidated with reference to the embodiments described hereinafter.
Exemplary embodiments of the invention will be described in the following with reference to the following drawings:
The recess 26 in the substrate is provided in a linear manner and can thus also be referred to as a slit recess. The recess 26 may be provided with an end wall section, e.g. formed by a U-formed enclosing substrate as shown in
In
The substrate of the electric circuit may be provided as one substrate portion or as several, segmented substrate part-portions, each mounted to the flat carrier base.
In an example, the wire is provided with a circumferentially enclosing electric insulation 32, which is removed at the end portion of the wire 18.
In an example, as shown in
In an example, provided as an option, the carrier 12 base comprises a flexible layer 34 and conductor paths attached to the flexible layer. For example, the carrier base is made from polyimide. The conductor paths are connected to the electric circuit. The conductor paths can also be referred to as contacts or circuit elements. In an example, the carrier base is multi-layered with at least two layers and the conductor paths are provided between the two layers.
In an example, provided as a further option but not further shown, the carrier base comprises a rigid layer.
In an example, the slit openings are provided as metalized slots in e.g. silicon contact pads. The conductive edge portions can also be referred to as bond pads with openings.
In
In an example, provided as an option, the substrate 16 of the electric circuit 14 is a rigid substrate made from silicon.
The wire connection has two functions. First, the mechanical connection holds the connected wire in place. Second, the conductive connection provides the electric connection.
In an example, provided as an option, the electric wire 18 is mechanically coupled with an adhesive 40 to edge portions of the substrate forming the recess.
In the example with the removed insulation 32 and the coupling with the adhesive 40, the two functions, mechanical connection and conductive connection, are provided separated from each other, but in the same location.
In the lower left, the carrier base 12 is shown with the slit opening 22 and the conductive edge portions 24. The substrate 16 with the recess 26 is below the carrier base 12.
As indicated more than one slit opening/recess arrangement can be provided. In
In the lower middle, the cable 18 is inserted into the recess 26. As indicated, the insulation 32 is removed at the end portion 28 of the cable 18.
In the lower right, the soldering is applied via the slit openings 22 connecting the end portion 28 of the cable 18 with the conductive edge portions 24.
In
In the lower left, the carrier base 12 is shown with the slit opening 22 and the conductive edge portions 24. The substrate 16 with the recess 26 is below the carrier base 12. In the lower middle left, the cable 18 is inserted into the recess 26. For example, the cable is attached and hold in place with a glue.
In the lower middle right, provided as an option, the end portion 28 of the wire 18 is provided with the circumferentially enclosing electric insulation 32, which is removed in alignment with the respective slit opening 22 on a side of the wire facing the slit opening 22. The enclosing electric insulation 32 is thus only removed in the area of the slit opening 22. In an example, the electric insulation 32 is removed by laser, for example, once the end portion 28 of the wire is placed in the recess 26. In an example, the electric insulation 32 is removed after further attachment of the wire, e.g. by the glue. In another example, the electric insulation 32 is removed before further attachment.
In the lower right, the soldering is applied via the slit openings 22 connecting the end portion 28 of the cable 18 with the conductive edge portions 24.
In an example, the slit opening 22 is also provided by laser removing e.g. the polyimide layer, a glue (if present), and the wire insulation in the same laser removal process. In such workflow, the carrier base 12 may be provided without the slit openings 22 and the slit openings 22 are then provided during the third stage as shown in the lower middle right in
In
In an example, as shown in
Hence, overlapping recess and slit are provided. The slit opening 22 thus opens into the recess 26. The recess and the slit opening are aligned in an opening direction of the slit openings, i.e. so-to-speak aligned in a vertical direction. The first side can also be referred to as lower side or bottom side, and the recesses are arranged aligned below the slit openings provided in the carrier base that is arranged on an upper side of the substrate of the electric circuit.
In the example with aligned recess and slit, i.e. the overlapping recess and slit arrangement, the two functions, mechanical connection and conductive connection, are provided in an integrated manner e.g. by the solder connection.
In
In
In an example, the mechanical coupling is provided by an epoxy embedding.
The mechanical coupling provides a stress relief for the solder connection of the wire ends.
In an example, the adhesive is a glue, e.g. an epoxy glue.
In the example with displaced recess and slit, the two functions, mechanical connection and conductive connection, are provided separated from each other in two locations.
In an example, not further shown in detail, the at least one slit opening is arranged in line with the at least one recess, wherein the recess is having a longer extension than the slit opening such that a first part of the recess is provided with the slit opening in the carrier base and a second part is provided without a slit opening in the carrier base. Further, the wire is provided with an insulated section having a circumferential layer of electric insulation in a portion within the second part of the recess, in which insulated section the wire is mechanically coupled with an adhesive to edge portions of the substrate forming the recess. Still further, the wire is provided with a stripped end section without insulation in a portion within the first part of the recess, in which stripped end section the wire is connected by the soldering. The recess is thus longer than the slits such that the wire is separately mechanically connected and conductively connected.
The electric component is provided as at least one of the group of a sensor, a measurement unit and an application unit for an interventional device. For example, the electric component is a capacitive micromachined ultrasonic transducer (CMUT) or CMUT transducer array. The CMUT is for example used for at least one of an ultrasound imaging on an intravascular ultrasound (IVUS) device, a flow sensing and pressure sensing on a physiological measurement device (e.g. flow-wire, pressure-wire).
In an option, the electric component comprises a plurality of electric circuits. A plurality of interconnecting wires is provided between the electric circuits. Further, the interconnecting wires are connected by wire connections with the slit openings in the carrier base and the recesses in the substrates.
In an example, the interventional device is provided as a catheter or guidewire. In another example, the interventional device is provided as an ultrasound probe for intravascular ultrasound imaging.
The term “subject” may also be referred to as individual. The “subject” may further also be referred to as patient, although it is noted that this term does not indicate whether any illness or disease is actually present with the subject.
In a first step 102, also referred to as step a), a flat carrier base with at least one electric circuit provided on a substrate is provided. The substrate circuit is attached to the carrier base. Further, the carrier base is provided with at least one slit opening that is provided at least partly with a conductive edge portion, which edge portion is connected to the at least one electric circuit. Still further, the substrate is provided with at least one recess aligned with the location of the at least one slit opening in the carrier base.
In a second step 104, also referred to as step b), at least one electric wire for connection with the electric circuit is provided.
In a third step 106, also referred to as step c), an end portion of the at least one electric wire is arranged in the at least one recess.
In a fourth step 108, also referred to as step d), the end portion of the wire is attached to the conductive edge portion to conductively couple the end portion of the wire and the conductive edge portion. This can be for example be done by soldering or gluing with electrically conductive material (e.g. silver glue).
In an example, the substrate with the electric circuit is attached to the carrier base on a first side and the at least one electric wire is connected to the carrier base also on the first side. The soldering takes place through the at least one slit opening from a second side of the carrier base, the second side being opposite to the first side.
In an option, not shown in detail, in step c), the end portion of the wire is provided with a circumferentially enclosing electric insulation. Further, before step d), the insulation is removed in alignment with the respective slit opening on a side of the wire facing the slit opening.
It has to be noted that embodiments of the invention are described with reference to different subject matters. In particular, some embodiments are described with reference to method type claims whereas other embodiments are described with reference to the device type claims. However, a person skilled in the art will gather from the above and the following description that, unless otherwise notified, in addition to any combination of features belonging to one type of subject matter also any combination between features relating to different subject matters is considered to be disclosed with this application. However, all features can be combined providing synergetic effects that are more than the simple summation of the features.
While the invention has been illustrated, and described in detail in the drawings and foregoing description, such illustration and description are to be considered illustrative or exemplary and not restrictive. The invention is not limited to the disclosed embodiments. Other variations to the disclosed embodiments can be understood and effected by those skilled in the art in practicing a claimed invention, from a study of the drawings, the disclosure, and the dependent claims.
In the claims, the word “comprising” does not exclude other elements or steps, and the indefinite article “a” or “an” does not exclude a plurality. A single processor or other unit may fulfil the functions of several items re-cited in the claims. The mere fact that certain measures are re-cited in mutually different dependent claims does not indicate that a combination of these measures cannot be used to advantage. Any reference signs in the claims should not be construed as limiting the scope.
| Number | Date | Country | Kind |
|---|---|---|---|
| 18201007.4 | Oct 2018 | EP | regional |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/EP2019/077707 | 10/14/2019 | WO | 00 |
