Claims
- 1. A pseudotyped viral particle comprising a FV envelope protein.
- 2. A method for the preparation of the pseudotyped viral particle according to claim 1, which comprises:(i) introducing a recombinant retroviral vector into a complementation cell; (ii) culturing said complementation cell line under suitable conditions to permit the production of the said pseudotyped viral particle; and (iii) recovering said pseudotyped viral particle in the cell culture.
- 3. A mammalian cell infected with a pseudotyped viral particle according to claim 1.
- 4. A mammalian cell infected with a pseudotyped viral particle obtainable by a method according to claim 2.
- 5. A pharmaceutical composition comprising a therapeutically or prophylactically effective amount of a pseudotyped viral particle according to claim 1.
- 6. A pharmaceutical composition comprising a therapeutically or prophylactically effective amount of a pseudotyped viral particle obtainable by a method according to claim 2.
- 7. A pharmaceutical composition comprising a therapeutically or prophylactically effective amount of a pseudotyped viral particle obtained from a mammalian cell according to claim 3.
- 8. A pharmaceutical composition comprising a therapeutically or prophylactically effective amount of a pseudotyped viral particle obtained from a mammalian cell according to claim 4.
- 9. A method for treating a disease which comprises administering a therapeutically effective amount of a pseudotyped viral particle according to claim 1.
- 10. A method for treating a disease which comprises administering a therapeutically effective amount of a pseudotyped viral particle obtainable by a method according to claim 4.
- 11. A method for treating a disease which comprises administering a therapeutically effective amount of a pseudotyped viral particle obtained from a mammalian cell according to claim 3.
- 12. A method for treating a disease which comprises administering a therapeutically effective amount of a pseudotyped viral particle obtained from a mammalian cell according to claim 4.
Parent Case Info
This application is a divisional of application Ser. No. 09/617,917, filed Jul. 17, 2000, which in turn is a divisional of application Ser. No. 09/305,086, filed May 4, 1999, U.S. Pat. No. 6,274,722 which in turn is a divisional of application Ser. No. 08/816,439, filed Mar. 14, 1997 U.S. Pat. No. 5,929,222.
Non-Patent Literature Citations (3)
Entry |
Goepfert et al., Journal of Virology, 71(1):778-784 (1997). |
Mahnke et al., Journal of Virological Methods, 29:13-22 (1990). |
Russell et al., J. Virol., 71(1):217-222 (1996). |