Claims
- 1. A protein having fibronectin binding activity, wherein said protein is encoded by a hybrid DNA molecule from Staphylococcus aureus wherein the hybrid DNA molecule consists of the following nucleotide sequence: ##STR4## wherein said protein is produced by a process comprising the steps of a) cloning said hybrid DNA molecule into a microorganism such that said DNA is expressed by said microorganism;
- b) cultivating the microorganism in a growth promoting medium; and
- c) lysing the cloned microorganism.
- 2. A protein from Staphylococcus aureus having fibronectin binding activity wherein the protein consists of one amino acid sequence selected from the group consisting of: ##STR5## wherein said protein is produced by a process comprising the steps of a) cloning at least one hybrid DNA molecule encoding said protein into a microorganism such that said DNA is expressed by said microorganism;
- b) cultivating the microorganism in a growth promoting medium; and
- c) lysing the cloned microorganism.
- 3. A composition comprising a protein according to claim 2 and a carrier exogenous to Staphylococcus aureus.
- 4. A composition comprising a protein according to claim 2 and a carrier therefor.
- 5. A fusion protein comprising a protein according to claim 2.
- 6. A fusion protein comprising a protein according to claim 1.
- 7. A protein according to claim 1, wherein said microorganism is E. coli.
- 8. A protein according to claim 2, wherein said microorganism is E. coli.
Priority Claims (1)
Number |
Date |
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Kind |
8901687 |
May 1989 |
SEX |
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Parent Case Info
This application is a divisional of application Ser. No. 08/340,458, filed Nov. 14, 1994, U.S. Pat. No. 5,320,951 which is a continuation of Ser. No. 07/974,181, filed Nov. 10, 1992, now abandoned which is a divisional of Ser. No. 07/520,808, filed May 9, 1990, now issued as U.S. Pat. No. 5,175,096.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
5320951 |
Hook et al. |
Jun 1994 |
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5571514 |
Hook et al. |
Nov 1996 |
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5652217 |
Hook et al. |
Jul 1997 |
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Non-Patent Literature Citations (2)
Entry |
Watson et al. 1987 in: Molecular Biology of The Gene, fourth edition, Benjamin/Cummings Publ. Co., Inc., Menlo Park, CA, p. 313. |
Flock et al. 1987 EMBO J. 6(8):2351-2357. |
Divisions (2)
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Number |
Date |
Country |
Parent |
340458 |
Nov 1994 |
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Parent |
520808 |
May 1990 |
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Continuations (1)
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Number |
Date |
Country |
Parent |
974181 |
Nov 1992 |
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