Claims
- 1. An isolated nucleic acid molecule comprising a portion of SEQ ID NO: 3, wherein said portion is at least 10 nucleotides in length and includes nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene, and wherein said nucleic acid molecule comprises a mutant allele of said GK gene at said nucleotide position 29.
- 2. A complement strand of a nucleic acid molecule, wherein said nucleic acid molecule comprises a portion of SEQ ID NO: 3, wherein said portion is at least 10 nucleotides in length and includes nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene, and wherein said nucleic acid molecule comprises a mutant allele of said GK gene at said nucleotide position 29.
- 3. The nucleic acid molecule of claim 1, wherein said portion is at least 20 nucleotides in length.
- 4. The nucleic acid molecule of claim 1, wherein said portion is at least 50 nucleotides in length.
- 5. The nucleic acid molecule of claim 1, wherein said mutant allele comprises a nucleotide selected from the group consisting of a guanosine, a thymidine, and a cytidine at said nucleotide position 29.
- 6. The nucleic acid molecule of claim 5, wherein said nucleic acid molecule comprises a guanosine at said nucleotide position 29.
- 7. The nucleic acid molecule of claim 1, wherein the nucleic acid molecule is selected from the group consisting of DNA, RNA, and polypeptide nucleic acid (PNA).
- 8. The nucleic acid molecule of claim 1, wherein the nucleic acid molecule comprises a label.
- 9. The nucleic acid molecule of claim 8, wherein the label is selected from the group consisting of a radioisotope, a fluorescent compound, an enzyme, and an enzyme cofactor.
- 10. The nucleic acid molecule of claim 1, wherein the nucleic acid molecule is immobilized on a solid support.
- 11. The nucleic acid molecule of claim 10, wherein the nucleic acid molecule is one of an array of two or more different nucleic acid molecules immobilized on said solid support.
- 12. An isolated nucleic acid molecule comprising SEQ ID NO: 3, wherein said nucleic acid molecule comprises a mutant allele at nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene.
- 13. A complement strand of a nucleic acid molecule, wherein said nucleic acid molecule comprises SEQ ID NO: 3, wherein said nucleic acid molecule comprises a mutant allele at nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene.
- 14. The nucleic acid molecule of claim 12, wherein said nucleic acid molecule is at least 250 nucleotides in length.
- 15. The nucleic acid molecule of claim 12, wherein said mutant allele comprises a nucleotide selected from the group consisting of a guanosine, a thymidine, and a cytidine at said nucleotide position 29.
- 16. The nucleic acid molecule of claim 15, wherein said nucleic acid molecule comprises a guanosine at said nucleotide position 29.
- 17. The nucleic acid molecule of claim 12, wherein the nucleic acid molecule is selected from the group consisting of DNA, RNA, and polypeptide nucleic acid (PNA).
- 18. The nucleic acid molecule of claim 12, wherein the nucleic acid molecule comprises a label.
- 19. The nucleic acid molecule of claim 18, wherein the label is selected from the group consisting of a radioisotope, a fluorescent compound, an enzyme, and an enzyme cofactor.
- 20. The nucleic acid molecule of claim 12, wherein the nucleic acid molecule is immobilized on a solid support.
- 21. The nucleic acid molecule of claim 20, wherein the nucleic acid molecule is one of an array of two or more different nucleic acid molecules immobilized on said solid support.
- 22. An isolated nucleic acid molecule which specifically hybridizes to a portion of SEQ ID NO: 3, wherein said portion is at least 10 nucleotides in length and includes nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene, and wherein said nucleic acid molecule comprises a mutant allele of said GK gene at said nucleotide position 29.
- 23. An isolated nucleic acid molecule consisting of a portion of SEQ ID NO: 3, wherein said portion is at least 10 nucleotides in length and includes nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene, and wherein said nucleic acid molecule comprises a mutant allele of said GK gene at said nucleotide position 29.
- 24. An isolated nucleic acid molecule consisting of SEQ ID NO: 3, wherein said nucleic acid molecule comprises a mutant allele at nucleotide position 29 of exon 10 of a glycerol kinase (GK) gene at said nucleotide position 29.
RELATED APPLICATIONS
[0001] This application is a divisional of U.S. application Ser. No. 09/694,088, filed Oct. 20, 2000, which claims the benefit of U.S. Provisional Application No. 60/161,141, filed Oct. 22, 1999. The entire teachings of the referenced applications are incorporated herein by reference.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60161141 |
Oct 1999 |
US |
Divisions (1)
|
Number |
Date |
Country |
Parent |
09694088 |
Oct 2000 |
US |
Child |
10827131 |
Apr 2004 |
US |