Claims
- 1. An isolated polynucleotide comprising a polynucleotide fragment of at least 30 bases from SEQ ID NO:1.
- 2. The isolated polynucleotide of claim 1, wherein the polynucleotide fragment is of at least 50 bases.
- 3. An isolated polynucleotide comprising a polynucleotide fragment of at least 30 bases from the cDNA contained in ATCC Deposit No. 75855.
- 4. The isolated polynucleotide of claim 3, wherein the polynucleotide fragment is of at least 50 bases.
- 5. An isolated polynucleotide of at least 30 bases which hybridizes to SEQ ID NO: 1 or the complement of SEQ ID NO:1, wherein said hybridization takes place under hybridization conditions comprising hybridization in a buffer consisting of 0.5 M NaPO4, pH7.4, and 7% SDS overnight at 65.degree. C., and wash in a buffer consisting of 0.5.times.SSC and 0.1% SDS at 60.degree. C.
- 6. The isolated polynucleotide of claim 5, wherein the polynucleotide encodes a biologically active fragment of hABH.
- 7. The isolated polynucleotide of claim 5, wherein the polynucleotide encodes a polypeptide which binds an antibody of hABH.
- 8. An isolated polynucleotide of at least 30 bases which hybridizes to the cDNA contained in ATCC Deposit No. 75855, wherein said hybridization takes place under hybridization conditions comprising hybridization in a buffer consisting of 0.5 M NaPO4, pH7.4, and 7% SDS overnight at 65.degree. C., and wash in a buffer consisting of 0.5.times.SSC and 0.1% SDS at 60.degree. C.
- 9. The isolated polynucleotide of claim 8, wherein the polynucleotide encodes a biologically active fragment of hABH.
- 10. The isolated polynucleotide of claim 8, wherein the polynucleotide encodes a polypeptide which binds an antibody of hABH.
- 11. An isolated polynucleotide of at least 30 bases which hybridizes to human hABH RNA or the complement of human hABH RNA, wherein said hybridization takes place under hybridization conditions comprising hybridization in a buffer consisting of 0.5 M NaPO4, pH7.4, and 7% SDS overnight at 65.degree. C., and wash in a buffer consisting of 0.5.times.SSC and 0.1% SDS at 60.degree. C.
- 12. The isolated polynucleotide of claim 11, wherein the polynucleotide encodes a biologically active fragment of hABH.
- 13. The isolated polynucleotide of claim 11, wherein the polynucleotide encodes a polypeptide which binds an antibody of hABH.
- 14. The polynucleotide of claim 1 fused to a polynucleotide which encodes a heterologous polypeptide.
- 15. The polynucleotide of claim 2 fused to a polynucleotide which encodes a heterologous polypeptide.
- 16. The polynucleotide of claim 3 fused to a polynucleotide which encodes a heterologous polypeptide.
- 17. The polynucleotide of claim 4 fused to a polynucleotide which encodes a heterologous polypeptide.
- 18. The polynucleotide of claim 5 fused to a polynucleotide which encodes a heterologous polypeptide.
- 19. The polynucleotide of claim 6 fused to a polynucleotide which encodes a heterologous polypeptide.
- 20. The polynucleotide of claim 7 fused to a polynucleotide which encodes a heterologous polypeptide.
- 21. The polynucleotide of claim 8 fused to a polynucleotide which encodes a heterologous polypeptide.
- 22. The polynucleotide of claim 9 fused to a polynucleotide which encodes a heterologous polypeptide.
- 23. The polynucleotide of claim 10 fused to a polynucleotide which encodes a heterologous polypeptide.
- 24. The polynucleotide of claim 11 fused to a polynucleotide which encodes a heterologous polypeptide.
- 25. The polynucleotide of claim 12 fused to a polynucleotide which encodes a heterologous polypeptide.
- 26. The polynucleotide of claim 13 fused to a polynucleotide which encodes a heterologous polypeptide.
- 27. A recombinant vector that contains the polynucleotide of claim 1.
- 28. A recombinant vector that contains the polynucleotide of claim 2.
- 29. A recombinant vector that contains the polynucleotide of claim 3.
- 30. A recombinant vector that contains the polynucleotide of claim 4.
- 31. A recombinant vector that contains the polynucleotide of claim 5.
- 32. A recombinant vector that contains the polynucleotide of claim 6.
- 33. A recombinant vector that contains the polynucleotide of claim 7.
- 34. A recombinant vector that contains the polynucleotide of claim 6.
- 35. A recombinant vector that contains the polynucleotide of claim 7.
- 36. A recombinant vector that contains the polynucleotide of claim 10.
- 37. A recombinant vector that contains the polynucleotide of claim 11.
- 38. A recombinant vector that contains the polynucleotide of claim 12.
- 39. A recombinant vector that contains the polynucleotide of claim 13.
- 40. A genetically engineered host cell that contains the polynucleotide of claim 1.
- 41. A genetically engineered host cell that contains the polynucleotide of claim 2.
- 42. A genetically engineered host cell that contains the polynucleotide of claim 3.
- 43. A genetically engineered host cell that contains the polynucleotide of claim 4.
- 44. A genetically engineered host cell that contains the polynucleotide of claim 5.
- 45. A genetically engineered host cell that contains the polynucleotide of claim 6.
- 46. A genetically engineered host cell that contains the polynucleotide of claim 7.
- 47. A genetically engineered host cell that contains the polynucleotide of claim 8.
- 48. A genetically engineered host cell that contains the polynucleotide of claim 9.
- 49. A genetically engineered host cell that contains the polynucleotide of claim 10.
- 50. A genetically engineered host cell that contains the polynucleotide of claim 11.
- 51. A genetically engineered host cell that contains the polynucleotide of claim 12.
- 52. A genetically engineered host cell that contains the polynucleotide of claim 13.
Parent Case Info
This is a Division of Application Ser. No. 08/783,266, filed Jan. 15, 1997, and issued as U.S. Pat. No. 5,747,312 on May 5, 1998, which is a Division of application Ser. No. 08/463,975, filed Jun. 5, 1995 and issued as U.S. Pat. No. 5,618,717 on Apr. 8, 1997, which claims priority as a CIP from PCT/US94/12058, filed Oct. 21, 1994.
Non-Patent Literature Citations (5)
Entry |
Lindahl et al. (1988) Ann. Rev. Biochem 57:133-157. |
Kataoka et al. (1985) Mol. & Gen. Genetics 198:263-269. |
Chen et al. (1989) PNAS 86:7961-7965. |
Chen et al. (1994) J. Bacteriol. 176(20):6255-6261. |
Kondo et al. (1986) JBC 261:15772-15777. |
Divisions (2)
|
Number |
Date |
Country |
Parent |
783,266 |
Jan 1997 |
|
Parent |
463,975 |
|
|