Claims
- 1. A method for identifying the presence of a growth factor that affects the self-regeneration of human hematopoietic stem cells, said method comprising:
- combining a composition suspected of containing at least one growth factor that affects the self-regeneration of human hematopoietic stem cells with a composition comprising human hematopoietic stem cells and having fewer than 5% lineage committed cells, wherein said human hematopoietic stem cells are characterized as Thy-1+, capable of self regeneration, and differentiation to members of the lymphoid, erythroid and myelomonocytic lineages; and
- determining the self-regeneration of said stem cells as a function of the presence of at least one of said growth factors in said composition, wherein said stem cell self-regeneration is indicative of the presence of a growth factor that affects the self-regeneration of human hematopoietic stem cells in said composition.
- 2. A method according to claim 1, wherein said human hematopoietic stem cells are further characterized by being CD34.sup.+ and lin.sup.-.
CROSS-REFERENCE TO RELATED APPLICATION
This application is a continuation-in-part of application Ser. No. 502,616, filed Mar. 30, 1990 now U.S. Pat. No. 5,061,620.
US Referenced Citations (5)
Continuation in Parts (1)
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Number |
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502616 |
Mar 1990 |
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