Claims
- 1. A monoclonal antibody which inhibits the ability of Factor XIII to catalyze the formation of a blood clot, wherein said antibody inhibits thrombin cleavage of said Factor XIII but does not bind to the thrombin-cleavage site of said Factor XIII, wherein said antibody binds to the same epitope on Factor XIII as antibodies selected from the group consisting of 9C11 produced by the hybridoma having the accession number ATCC CRL 11458 and 10G10 produced by the hybridoma having the accession number ATCC CRL 11457.
- 2. The monoclonal antibody of claim 1, wherein said antibody is selected from the group consisting of 9C11 produced by the hybridoma having the accession number ATCC CRL 11458 and 10G10 produced by the hybridoma having the accession number ATCC CRL 11457.
STATEMENT AS TO FEDERALLY SPONSORED RESEARCH
This invention was supported in part by grant K08, HL02348 from the National Institutes of Health. The U.S. Government therefore has certain rights in the invention.
Foreign Referenced Citations (1)
Number |
Date |
Country |
9215609 |
Sep 1992 |
WOX |