Claims
- 1. A compound of formula I, including pharmaceutically acceptable salts thereof,
- 2. A compound of claim 1 having the formula
- 3. A compound of claim 2 wherein R1 is cyclopropyl.
- 4. A compound of claim 2 wherein R2 is phenyl.
- 5. A compound of claim 2 wherein R3 is methoxy.
- 6. A compound of claim 2 wherein R4 is NH2 or tert-butoxycarbonylNH—.
- 7. A compound of claim 2 wherein Q is —(CH2)nCH═C— and n is 1-5.
- 8. A compound of claim 7 wherein n is 3 or 4.
- 9. A compound of claim 1 having the formula
- 10. A compound of claim 9 wherein n is 3 or 4.
- 11. A compound of claim 2 wherein:
- 12. A pharmaceutical composition, comprising a compound of claims 1-11, and a pharmaceutically acceptable carrier.
- 13. A method of inhibiting HCV NS3 protease which comprises administering to a mammal in need of such treatment a therapeutically effective amount of a compound of claims 1-11.
- 14. A method of treating an HCV infection, in a mammal in need thereof, comprising the administration to said mammal of a therapeutically effective amount of a compound of claims 1-11.
REFERENCE TO RELATED APPLICATIONS
[0001] This application claims the benefit of U.S. Provisional Application Serial No. 60/382,103 filed May 20, 2002 and No. 60/344,080 filed Dec. 20, 2001.
Provisional Applications (2)
|
Number |
Date |
Country |
|
60382103 |
May 2002 |
US |
|
60344080 |
Dec 2001 |
US |