Claims
- 1. A compound of the formula: ##STR42## wherein one of A' or B' is a group of the formula: ##STR43## and the other of A' or B' is H wherein R.sub.0 is H or F, R.sub.2 is H, lower alkenyl, or substituted or unsubstituted lower alkyl with the substituents selected from 1 to 3 aryl groups, and r is an integer from 0-2;
- R' is H, substituted or unsubstituted lower alkyl with the substituents selected from 1 to 3 aryl groups; ##STR44## wherein R.sub.3 and R.sub.4 are H, substituted or unsubstituted lower alkyl with the substituents selected from 1 to 3 aryl groups, and each R.sub.5 is independently H, lower alkyl, or both groups R.sub.5 taken together are a six membered ring which may be aromatic.
- 2. A compound of the formula: ##STR45## wherein A', B', and R.sup.1 are as in claim 1 and R.sub.8 is H or lower alkyl.
- 3. The compound of claim 2 wherein A' is ##STR46## and B' is H, and R.sub.0, r, and R.sub.2 are as in claim 1.
- 4. The compound of claim 3 wherein r=0.
- 5. The compound of claim 4 wherein R' is lower alkyl and R.sub.8 is H said compound having the formula: ##STR47##
- 6. A compound of the formula: ##STR48## wherein A', B', and R.sup.1 are as in claim 1 and R.sub.8 is H or lower alkyl.
- 7. The compound of claim 6 wherein A' is ##STR49## and B' is H and R.sub.0, r, and R.sub.2 are as in claim 1.
- 8. The compound of claim 7 wherein r=0.
- 9. The compound of claim 8 wherein R' is lower alkyl and R.sub.2 is t-butyl said compound having the formula: ##STR50##
- 10. The compound of claim 6 wherein R.sub.1 is H and R.sub.2 is t-butyl said compound having the formula: ##STR51##
- 11. The compound of claim 6 wherein r=1 and R.sub.0 is H.
- 12. The compound of claim 11 wherein R' is lower alkyl and R.sub.2 is t-butyl said compound having the formula: ##STR52##
- 13. The compound of claim 12 wherein R' is H and R.sub.2 is t-butyl said compound having the formula: ##STR53##
- 14. The compound of claim 3 wherein R.sub.2 is tert-butyl, r is 1, R.sub.0 is H and said compound has the formula: ##STR54##
- 15. The compound of claim 4 wherein R.sub.2 is tert-butyl and said compound has the formula: ##STR55##
RELATED U.S. APPLICATION DATA
This is a division of application Ser. No. 07/732,435 filed Jul. 18, 1991, now U.S. Pat. No. 5,182,263, which is a continuation of application Ser. No. 07/311,872, filed Feb. 21, 1989, now abandoned, which is a Continuation in-part of pending U.S. patent application Ser. No. 185,228 filed Apr. 25, 1988, abandoned.
US Referenced Citations (3)
Non-Patent Literature Citations (1)
Entry |
Bodanszky et al., J. Med. Chem. 21, 1030-1035 (1978). |
Divisions (1)
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Number |
Date |
Country |
Parent |
732435 |
Jul 1991 |
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Continuations (1)
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Number |
Date |
Country |
Parent |
311872 |
Feb 1989 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
185228 |
Apr 1988 |
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