Claims
- 1. An isolated nucleic acid which encodes a heavy chain region of an antibody which binds to a Lewis B antigen, said heavy chain region having the amino acid sequence of SEQ ID NO: 20.
- 2. An isolated nucleic acid molecule which encodes a light chain region of an antibody which binds to a Lewis B antigen, said light chain region having the amino acid sequence of SEQ ID NO: 21.
- 3. A host cell transfected or transformed with (i) an isolated nucleic acid molecule which encodes a heavy chain of an antibody which binds to a Lewis B antigen, said heavy chain region having the amino acid sequence of SEQ ID NO: 20 and (ii) an isolated nucleic acid molecule which encodes a light chain of an antibody which specifically binds to a Lewis B antigen, said light chain region having the amino acid sequence of SEQ ID NO: 21.
- 4. An isolated nucleic acid molecule having a nucleotide sequence selected from the group consisting of SEQ ID NO: 22 and SEQ ID NO: 24.
- 5. An expression vector comprising the isolated nucleic acid molecule of claim 1, in functional combination with a promoter sequence.
- 6. An expression vector comprising the isolated nucleic acid molecule of claim 2 in functional combination with a promoter sequence.
- 7. An expression vector comprising the isolated nucleic acid molecule having the nucleotide sequence encoding the amino acid sequence of SEQ ID NO:20 and the isolated nucleic acid molecule having the nucleotide sequence encoding the amino acid sequence of SEQ ID No. 21 in functional combination with a promoter sequence.
- 8. An expression vector comprising an isolated nucleic acid molecule of claim 4 in functional combination with a promoter sequence.
- 9. A host cell transfected or transformed with an expression vector according to claim 5.
- 10. A host cell transfected or transformed with an expression vector according to claim 6.
- 11. A host cell transfected or transformed with an expression vector according to claim 7.
- 12. A host cell transfected or transformed with an expression vector according to claim 8.
CROSS REFERENCE TO RELATED APPLICATION
This Application is a division application of prior application Ser. No. 08/388,672 filed Feb. 14, 1995 now U.S. Pat. No. 5,795,961. The entire disclosure of application Ser. No. 08/388,672 is incorporated herein by reference.
Divisions (1)
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Number |
Date |
Country |
Parent |
388672 |
Feb 1995 |
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