Medical device communication method

Abstract
A medical device communication method that may be implemented within a variety of medical devices including but not limited to infusion pumps. The method may be implemented with a protocol stack for at least intra-device communication. Embodiments provide connection-oriented, connectionless-oriented, broadcast and multicast data exchange with priority handling of data, fragmentation, and reassembly of data, unique static and dynamic address assignment and hot swap capability for connected peripherals or subsystems.
Description
INCORPORATION BY REFERENCE TO ANY PRIORITY APPLICATIONS

Any and all applications for which a foreign or domestic priority claim is identified in the Application Data Sheet as filed with the present application are hereby incorporated by reference under 37 CFR 1.57.


BACKGROUND OF THE INVENTION
Field of the Invention

One or more embodiments of the invention are related to the field of multiplex communication protocols for medical devices such as, but not limited to, infusion pumps. More particularly, but not by way of limitation, embodiments of the invention enable a medical device communication method for communication between connected peripherals and subsystems that includes connection-oriented, connectionless-oriented, broadcast and multicast data exchange with priority handling of data, fragmentation and reassembly of data, unique static and dynamic address assignment and hot swap capabilities.


Description of the Related Art

Devices that exchange data generally do so using a communication protocol. Communication protocols enable data to be transmitted and received in a controlled manner. Medical devices are example devices that may utilize a communication protocol, for example to exchange data between peripherals or subsystems that generate or utilize data. There are many types of communications protocols that vary in complexity, efficiency and hardware utilization. Current communication protocols utilized within medical devices make use of the operating system and particular bus architecture within the medical device. A problem with this type of architecture is that some implementations may prevent time-multiplexed access of the communication link, thereby starving or otherwise preventing multiple applications from communicating simultaneously. In addition, applications that transfer data using operating system and bus specific software calls must be altered when the operating system or bus architecture changes, specifically to account for differences in operating system calls or with respect to the bus architecture, different data formatting, sequencing and any other protocol specific nuances. In addition, medical devices in general must undergo extensive testing to ensure that they do not fail. Thus, changing bus architectures increases costs associated with applications that make use of the bus architecture, since the application must be retested if the source code for the application is altered.


Known communications protocols are generally targeted at a specific type of communication bus architecture, for example Ethernet, WiFi, Bluetooth, CAN, Serial, I2C, SPI, etc. Known communication protocols in general are not capable of use with more than one type of communication bus since they attempt to provide a solution to a specific communication problem in a coherent manner. Because of the low power requirements, limited processor capabilities and limited memory capacity of medical devices with embedded processors that do specific functions or tasks, such as infusion pumps, existing sophisticated communications protocols are generally not utilized in such medical devices.


In summary, known solutions use communication protocols that are tied to a specific operating system and/or communications bus. Unfortunately, these communication protocols are not agnostic to all communication bus types and do not provide an efficient and lightweight protocol stack for intra-device communication that includes connection-oriented, connectionless-oriented, broadcast and multicast data exchange with priority handling of data, fragmentation, and reassembly of data, unique static and dynamic address assignment for connected subsystems and hot swap capabilities. For at least the limitations described above there is a need for a medical device communication method that provides these features as described and claimed herein.


SUMMARY OF THE INVENTION

Embodiments of the invention enable a medical device communication method for communication between medical peripherals and subsystems that includes connection-oriented, connectionless-oriented, broadcast and multicast data exchange with priority handling of data, fragmentation and reassembly of data, unique static and dynamic address assignment and hot swap capabilities. Example medical devices that may employ an embodiment of the invention include but are not limited to infusion pumps, both present and future. Embodiments of the communication protocol provide an interface that is detached, or otherwise abstracted from the operating system and underlying bus architecture within the medical device, making the behavior and interface of communication protocol consistent across bus architectures and operating systems, which is unknown in the art of infusion pumps for example. Hence, the same application may be utilized on multiple hardware platforms, for example without altering the application itself. Thus, embodiments enable simplified application code, portability thereof and minimize maintenance and testing requirements. Embodiments may utilize any type of physical communication path, for example wireless or hardwired, including but not limited to a data bus. Embodiments for intra-device communications over a data bus generally employ data bus drivers specific to each type of data bus to control reading and writing of data over the bus along with a standard interface to these data bus drivers.


Embodiments may be implemented in separate layers of software configured to execute on one or more computing elements, wherein each layer performs operations to provide data exchange that is generally independent of the other layers. Each layer for example may create, read or update headers associated with data to be exchanged, wherein the headers contain information to support the above-mentioned features. The layers make up what is known as a protocol stack. Embodiments of the protocol stack may include a manager layer, session layer, transport layer, and data link layer or any other architecture as long as the resulting implementation provides the functionality described herein.


Depending on the peripheral or subsystem, data type, priority and desired reliability of data to be exchanged, applications may transmit data using connection-oriented data exchange to provide guaranteed delivery of data or connectionless data exchange for less sensitive data. Embodiments also support one-to-one, as well as one-to-many and many-to-one multicast, and broadcast modes of data exchange between connected peripherals and subsystems. At least one embodiment also supports priority based data exchange and gives preference to high priority data over low priority data to ensure that high priority messages are delivered first. Additionally, at least one embodiment supports data fragmentation and reassembly data to comply with demands of the particular physical communication technology. Embodiments also provide unique static and dynamic address assignment for connected subsystems and hot swap capabilities, which are unknown for example in current infusion pumps.


Specifically, in the case of connection-oriented communication, at least one embodiment utilizes a Communication ID or “CID”, as a token to uniquely identify all active connections within a subsystem and route the data between respective applications. In the case of connectionless communications, at least one embodiment uses port numbers, for example source and destination port numbers, to identify the targeted application. At least one embodiment supports subscription services for recipient applications, which enables multicasting of data to all subscribed applications. Multicasting can be both connection-oriented and connectionless. In connection-oriented communication sessions, at least one embodiment guarantees delivery of data, for example using acknowledgements. Alternatively, connectionless communication sessions do not guarantee delivery of data, but are very efficient. At least one embodiment supports broadcasting of data/messages, wherein the broadcast messages are forwarded to all the subsystems connected to the broadcasting subsystem.


Applications may need to exchange data larger in size than an underlying communication technology or data bus can support. In such cases, at least one embodiment breaks or fragments the data into a smaller size, for example that the data bus can actually transfer. At least one embodiment reassembles data into the original data size at the receiving end. At least one embodiment executes on embedded systems that may have limited resources, including memory, processing power, bus utilization, and power. Hence, embodiments efficiently utilize available resources. Example data exchanges that are large enough to warrant fragmentation of messages include drug library downloads and firmware updates.


With respect to fragmentation, at least one embodiment utilizes window that represents a count of fragments that may be sent before receiving an acknowledgement from receiver. In at least one embodiment, the transmitter requests for window size from the receiver before sending the first fragment. The receiver determines the available memory space to accommodate received packets and responds with the window size, for example as an integral multiple of the maximum frame size that fits into the available memory. The transmitter numbers the fragments in sequence and sends them to receiver. After a window size worth of messages have been sent, the transmitter waits for an acknowledgement of the last fragment. The receiver accumulates all the received fragments and verifies that all the received fragments are in sequence. If there is no missing fragment, the receiver sends the fragment number of last fragment as an acknowledgement, or otherwise sends the fragment numbers of missing fragments as part of negative acknowledgement or NAK.


Since medical devices such as infusion pumps in the future may include hot swappable peripherals or subsystems, at least one embodiment supports unique address assignments to connected devices in order to provide conflict free exchange of data, thus reducing complexity in applications. At least one embodiment supports communication over multiple underlying data transfer technologies such as serial, CAN, SPI, SDIO, USB, or any other type of physical medium or data bus. At least one embodiment also keeps track of devices connected on each bus and routes data onto the respective bus.





BRIEF DESCRIPTION OF THE DRAWINGS

The above and other aspects, features and advantages of the invention will be more apparent from the following more particular description thereof, presented in conjunction with the following drawings wherein:



FIG. 1 illustrates an architectural view of a system having a user interface controller, and multiple peripherals that communicate with one another using an embodiment of the invention.



FIG. 2 illustrates a hierarchical layered embodiment of the invention implemented as a protocol stack.



FIG. 3 illustrates an embodiment of an address request method implemented within the manager layer.



FIG. 4 illustrates an embodiment of a simple infusion sequence utilizing various messages provided by embodiments of the method.



FIG. 5 illustrates an embodiment of a connection method implemented within the session layer.



FIG. 6 illustrates an embodiment of a data exchange method implemented within the session layer.



FIG. 7 illustrates an embodiment of a disconnection request method implemented within the session layer.



FIG. 8 illustrates a layer flow diagram that shows the flow of data within the various layers implemented in at least one embodiment of the invention.



FIG. 9 illustrates an activity diagram showing routing between various devices.



FIGS. 10A-D illustrate the structure of the messages of the Session Layer.



FIGS. 11A-B illustrate the structure of the messages of the Transport Layer.



FIGS. 12A-B illustrate the structure of the messages of the Data Link/Physical Layer.



FIGS. 13A-B illustrate an exemplary message transfer of a medical function using exemplary values within the messages to demonstrate the system and method according to at least one embodiment of the invention.





DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENT

A medical device communication method will now be described. In the following exemplary description numerous specific details are set forth in order to provide a more thorough understanding of embodiments of the invention. It will be apparent, however, to an artisan of ordinary skill that the present invention may be practiced without incorporating all aspects of the specific details described herein. In other instances, specific features, quantities, or measurements well known to those of ordinary skill in the art have not been described in detail so as not to obscure the invention. Readers should note that although examples of the invention are set forth herein, the claims, and the full scope of any equivalents, are what define the metes and bounds of the invention.



FIG. 1 illustrates an architectural view of a system having user interface controller or “UIC”, and multiple peripherals that communicate with one another using an embodiment of the invention. As shown user interface controller UIC communicates with peripherals Pump Motor Control or “PMC”, PMC 1 and PMC 2 as well as communication engine or “CE” for various applications including but not limited to drug library, status and diagnostic message handling. For exemplary purposes, UIC has a destination/device ID, e.g., an address of 5 and messages from UIC to the other devices travel over pathways uniquely defined by the tuples defined in the table, for example on a per device and communication ID defined channel. These channels are shown in the table above UIC, namely between UIC and PMC 1, at ports 10 and 20, i.e., the therapeutic and status ports, via Communication ID or “CID” 100 and CID 250 respectively followed by a channel used between UIC and PMC 2 at port 10, the therapeutic port, via Communication ID 100, along with a channel between UIC and CE at port 40, via Communication ID 175. The CE, whose address is 7, shows channels in the table above CE to PMC 2 and the UIC, namely devices 2 and 5 via Communication ID's 250 and 175 respectively. PMC 1 is illustrated as having channels to the UIC, via Communication ID's 100 and 250. PMC 2 is illustrated as having channels to the UIC and CE through ports 10 and 20, via Communication ID's 100 and 250. PMC 3 and 4 may be hot swapped into the system or otherwise commanded or queried on the fly. Embodiments of the invention are generally configured to utilize minimal memory and processing to enable execution on devices having limited memory and limited processing power, which is generally unknown in the art with respect to sophisticated communications protocols for example. In one or more embodiments, the stack utilizes one kernel thread to execute the Data Link layer and Transport lower layer, whereas remaining layers are part of application process and execute in the context of application. Minimum thread implementation supports blocking access, for example read and write operations block until the operation is completed. Embodiments may also support asynchronous callbacks, and in such cases, the stack may utilize two threads, one for write operations and one for read operation, hence total number of threads utilized is 2*N+1, where N is the number of applications using the stack.



FIG. 2 illustrates a hierarchical layered embodiment of the invention implemented as a protocol stack. As shown, a data message in the application layer is N bytes long. The application layer may include any functionality independent of the protocol stack that is implemented in the layers beneath the application layer as shown. When the message is transmitted from one application to another, for example to an application executing on a peripheral or subsystem, control information or headers are appended to the message as the message descends layers. The various headers or other appended information are removed as the message rises through the protocol stack to the respective receiving application.


In one or more embodiments, a manager layer may be utilized to implement the first layer in the protocol stack beneath the application. The manager layer may provide standard interfaces to applications across any desired operating system. The layer provides application programmer interfaces or API's that enables socket-based communications between applications. The manager layer also manages file descriptors and facilitates opening of ports. In at least one embodiment, the manager layer creates and otherwise utilizes a message header having a port number and file descriptor.


A session layer is another layer in the protocol stack and provides or includes API's to exchange data and control between manager layer and session layer. The session layer may provide guaranteed application-to-application delivery of data and enables connection-oriented and connectionless-oriented modes of communication. This layer also enables one-to-one, one-to-many, many-to-one multicast and broadcasting mode of communication. The layer maintains the translation between CID and an associated socket or virtual port. For connection-oriented communication, the protocol utilizes the CID and otherwise generates and utilizes CID's. As the connection-oriented data exchange utilizes a handshake between applications for data exchange, the session layer handles the handshake and generates a CID for the communication and informs the other participating session layers of application(s) about the CID. After the handshake, data packets utilize the CID for communication. In case of connectionless communication, no CID is utilized and hence both source and destination port addresses are exchanged in each communication packet or payload. In at least one embodiment, the manager layer creates and otherwise utilizes a message header having control flags and a message type along with a communication identifier. This structure along with an exemplary connection table is shown in FIG. 10A, along with exemplary message types in FIGS. 10B-D. The control flags may be implemented with a layer flag of 1 bit, a connection type of 2 bits and a CID source of 1 bit for example. The session layer utilizes some messages that are associated with the session-session communications and are never passed up the stack to the manager layer in one or more embodiments. These messages are generally used for establishing or closing connections, acknowledgements, etc. If the layer flag is set, for example set to True or 1, the message will be consumed at session layer and will not be forwarded up the stack. The connection type flag indicates the type of connection, for example if connection-oriented, set to 01 or if connectionless, set to 00. An example connectionless protocol is User Datagram Protocol or UDP while an example connection-oriented protocol is Transmission Control Protocol or TCP. The CID source bit is used to identify if the data as being sent from the entity that generated CID for the connection in use or from sub-modules using this CID for communication. The entity that generates CID for communication sets this bit for all the messages generated by it for the respective active connection, while other entities involved in communication reset this flag for messages while using this CID. As the CID is unique within the entity generating CID, there may be duplicate CIDs across other entities. Hence, this layer helps in resolving the source of CID (local or remote) via this flag. The message type field associates messages with categories and lets the session layer know what to expect in the following fields. The message type field is a 4-bit wide field in one or more embodiments. The message type field is used to determine the type of message. Exemplary values include 0000 for data, 0001 for connection, 0010 for CID, 0011 for socket, 0100 for service and 0101 for device information. Any module that provides a service generates a unique CID for communicating with the consumers of the service. Communication ID ‘0’ is reserved for connectionless type of communication in one or more embodiments. Communication ID field is 1 byte wide and is utilized for the data that is passed up the protocol stack. CID can hold any number between 0-255. As state above, CID ‘0’ is for connectionless type communication and is thus not a valid ID for connection-oriented communication. Connection oriented type communications will have a CID in the range of 1-255. Hence, CID ‘0’ is an implicit indication of connectionless communication, any other number between 1-255 suggests connection-oriented. Applications may establish one or more notification filters to select message to receive and process using a desired function. The filtration mechanism may utilize one or more regular expression that specifies the location, length and content of the matching data in the data portion of the packet. This functionality is implemented in the management layer in one embodiment of the invention. Before the management layer forwards the data to application, it may check if any filters are defined on the data. Depending on the filter, the manager layer filters data and forwards the data to respective callback handlers.


Embodiments of the invention enable a single application to maintain connections with more than one device over one or more physical communication layers or bus implementations. This is accomplished by the use of virtual ports. A single application such as the Therapeutic Manager in the UIC may for example maintain open connections with more than one drug pump PMC or other device as would be asserted during a multi-channel infusion. Similarly, many applications may maintain a connection with one application or device, for example, UIC, CE, and other applications may connect to a particular PMC to gather infusion status information.


The one-to-many and/or many-to-one communication relationship can further be classified into three types, unicast, multicast and broadcast. For example, different applications can gather infusion status from a PMC either by requesting, for example via multicasting, or the PMC can broadcast its status on a known port and interested applications can listen to the port. Listening to a known port can be either anonymous or subscription based. In anonymous mode, broadcasting application continuously transmits on a known port and any application can listen to the port. In subscription based mode, the broadcasting application will not transmit until there is at least one recipient, interested application, which will have to request for service and disconnect when done using the service.


Virtual ports can be implemented by enabling a handshake between participating modules/applications. Applications providing the service generally open a port and connect to the port. For every accepted connection request, CID is generated by the service provider and is passed back to requesting entity in an acknowledgement. Subsequent communication is performed using this CID. In general, the CID is unique to the entity that generated it. A disconnection message is used to stop communication and the CID is then returned to the pool, for example to be reused later. If the service provider runs out of CIDs, it may return a NAK to incoming connection requests with appropriate NAK ID. In case of communication failure, for example module shut down, too much waiting time, too many retries, etc., after waiting for sufficient retries to send a message, one or more embodiments may assume that the communication has stopped and CID is then returned to pool. As the CID are generated by the service provider and are unique within the entity, there can be duplicate CIDs on other sub-entities. To avoid the conflict because of duplicate CIDs, two CID tables may be maintained, one for the CID generated by the system, and the other for the CIDs generated by other systems engaged in communication. The creator of CID sets the “CID Source” flag, hence when other involved applications look at this flag, they perform lookup in appropriate CID table. Each entity may therefor maintain a table shared by the applications running on it. This table is maintained at the session layer and serves as a reference table for routing incoming data packets to respective ports/sockets.


As example scenario is illustrated in the following table, and is also shown in the bottom portion of FIG. 10A for illustration purposes and is not intended to limit the invention as claimed. As shown, the connection type may be set to a value indicative of a connection-oriented type of communication, such as TCP as shown, or a connectionless communication type, such as UDP as shown, or a “Service”, for example an application that exists to log data for other applications. The destination address, destination port and communication ID generally uniquely identify a row in above-mentioned table. Destination address is the logical address of a device engaged in a communication. Embodiments may support repeated entries with the same destination address, which indicates multiple active connections with the same destination device. The source port field stores the local port number responsible for handling communication(s) with the CID associated therewith. Depending on CID, received messages are routed to the respective port. Multiple repeated entries in the source port column suggest various applications communicating over same port, which may be indicative of one-to-many communication for example. In one or more embodiments, applications may register or otherwise provide a request to a service provider to receive messages. The destination port is the port number on the destination device engaged in a communication. The communication between a destination port and the local port associated therewith takes place over the respective CID. Hence, CID behaves as a key for this communication. Since the CID is a unique number assigned to distinct communication requests, and which may be implemented with a particular data type of a certain size, there may be an upper limit to the number of active connections that can be handled by the system/application. The upper limit is thus an upper numerical limit of the CID. Once the count of unique CID's exceeds the upper limit, one or more embodiments send a NAK to new incoming connection requests. The File Descriptor (FD) functions similar to file handler or file descriptor in standard operating systems as one skilled in the art will recognize. Communication related operations are performed using this descriptor. Repeating entries of FD suggests multiple connections are being served by one application, many-to-one type of communication. See also FIGS. 10B-D for specific message structures utilized in one or more embodiments of the invention.

















Connection
Destination
Destination
Source

File


Type
Address
Port
Port
CID
Descriptor




















Service
8
50
40
100
55


TCP
5
23
60
72
63


Service
15
68
40
110
87


UDP
4
20
55
103
21









The transport layer is another layer in the protocol stack and is responsible for transport layer to transport layer delivery of data. This layer handles flow control, timeouts, acknowledgements and fragmentation and reassembly of data and also resolves the data priority. At least one embodiment of the protocol stack supports two or more priority levels, for example three priority levels, High priority, Medium priority and Low priority and depending on the priority of data, the transport layer puts the data in a respective priority queue. The transport layer may be implemented with two sub-layers namely the transport upper and lower layers. The transport upper layer along with manager and session layers resides in application space, whereas the transport lower layer along with data link layer resides in kernel space. The transport upper layer handles reading and writing to priority queues, fragmentation and reassembly of data and transport-to-transport layer acknowledgements, whereas the transport lower layer may be implemented as a very thin layer and handles reading from priority queues and communication with one or more other stack layers, for example a lower stack layer. This structure along with an exemplary message types in FIGS. 11A-B.


The transport layer generally ensures that manageable sized datagrams are sent over the underlying bus. Hence, this layer looks at the data coming from upper layers and if the size of data exceeds Maximum Transmission Unit (MTU) size, the layer fragments the incoming data to fit within MTU boundary. Thus, embodiments of the invention may utilize any type of bus of any size, e.g., one bit as per a serial bus, or multiple bits as per a parallel bus of any width. The layer adds appropriate information to the data so that it can be reassembled faithfully at the receiving end. If the incoming data can be sent in three fragments, ‘Fragment ID’ field is used to number the fragments starting from ‘1’ and the ‘Extended flag’ bit is not used. All zeros in the ‘Fragment ID’ field indicates an un-fragmented message and hence is treated as a standalone message. If a message requires more than three fragments to be transmitted, ‘Extended Flag’ is set, which enables an extra of 8 bits (Extended Fragment ID field is 8 bits) to be used for numbering the fragments. With this flag set, there are total of 10 bits available for numbering which can support 1023 (2^10−1) fragments. At the receiving end, ‘Extended flag’ is inspected to determine if ‘Extended Fragment ID’ is used or not. If the flag is set, the receiver assumes the fragments to arrive in sequence, starting from sequence number 1. But, if the flag is not set, the receiver inspects the ‘Fragment ID’ field. If the ‘Fragment ID’ field has zero in it, it indicates an independent message, but if it's a non-zero value, the receiver treats the received message as fragmented data (expects a maximum of three packets). Once all of the fragments are received, the receiver will re-assemble all the fragments into one message. To do this, the receiver aligns all the received messages in ascending order of their fragment ID. Then the receiver verifies that no fragment has been missed in the sequence. If all fragments are received successfully, the receiver removes the ‘Transport layer’ header information from all the related fragments and concatenates them into one message. If Transport layer has limited memory to re-assemble all the fragments, it forwards the fragments up the stack, as they arrive, which gets reassembled in application buffer.


Congestion control is also provided by the transport layer, which may implement messages dedicated specifically for transport layer to layer communication. These specific messages are consumed at transport layer and not passed up the stack. One such message is the window message, which is exchanged to determine window size for data exchange.


Before sending the first fragment from fragmented data, the transmitter requests a window size from receiver. The receiver looks at the available buffer space in the application buffer and computes the number of fragments it can stage before running out of available memory. It responds to transmitters request with this computed number as window size. Then the transmitter sends window size worth of fragments before expecting an acknowledgement. Once the receiver receives all the messages transmitted in a window, it verifies that all the fragments are in desired sequence and sends acknowledgement for last received fragment in the sequence. If the receiver determines that fragment(s) is missing, it sends an NAK for the missing fragment and the transmitter re-transmits the respective fragment(s). The transmitter may check for window size in middle of communication to keep the data exchange optimized, also, if the receiver gets low on resources, it can explicitly send a window response and update the transmitter about the window size.


The transport layer is also responsible for the reliable delivery of data. The transport layer has ability to ensure delivery of data to the receiving end. Transport layer has a field for acknowledgement. The receiver may send an acknowledgement for every received data packet with the acknowledgement flag set. In case of fragmented messages, an acknowledgement is sent when the last fragment in a window has been received or last frame in the message has been received or timer expires before all messages have been received.


Embodiments of the transport layer may also implement a “time to live”. For example, after transmitting a message, the transmitter initiates a timer and waits for an acknowledgement. If acknowledgement is received, the timer is reset and next packets are transmitted. But if no acknowledgement is received, the transport layer re-transmits the message and again waits for an acknowledgement. The transmitter will retry to send the message certain number of times and if it fails to get an acknowledgement, it will assume that the receiver is not available and will inform upper layers. In case of fragmentation, the transmitter sends window-sized messages and then waits for an acknowledgement on the last fragment sent. If the timer expires, the transmitter will resend the messages again.


The transport layer also may implement fault detection and recovery. For example, the transport layer at the receiver may request the transmitter to re-transmit selected frames through layer-to-layer messages.


The transport layer may also implement priority for messages. For example, the upper layers may pass the message priority down to this layer and this layer adds the priority to the message header. Header has a two bit fields for message priority and hence there are four priority levels possible in one or more embodiments although any number of bits may be used for priority to implement more levels and this applies to all message partitions and bit numbers described herein. Each priority level has its own queue and depending on message priority, transport layer puts them into respective queues to be processed by other layers. As there are four priority levels in a 2-bit embodiment, there may be a maximum of four priority queues and a minimum of one queue, but the number of priority queue depends on the number of priority levels used.


The data link layer is another layer, by way of example and not limitation the bottommost layer, in the communication stack and is responsible for subsystem-to-subsystem delivery of data. This layer completely resides in the kernel space. Data link layer may also be implemented with two sub-layers, for example a Link Layer and Media Access (MAC) layer. The link layer verifies data integrity by calculating/verifying CRC for each outgoing/incoming data frame and also handles any hardware acknowledgements for example. The layer also handles requests for unique logical addresses as well and generates and assigns unique addresses. The MAC layer utilizes driver(s) handling the underlying physical communication channels or bus(es). As the data frames arrive on the buses, the MAC layer copies the received data into a memory pool and passes the pointer to the copied data to Link layer. At least one embodiment supports communication over multiple underlying data transfer technologies or hardware implementations such as serial, CAN, SPI, SDIO, USB, or any other type of communications medium or data bus. This structure along with an exemplary message types in FIGS. 12A-B.


In one or more embodiments, the data link layer is responsible for data integrity, for example through the use of CRC checking or any other type data integrity coding or format desired. Embodiments of the data link layer are also responsible for logical address assignment. For example, this layer is responsible for assigning and managing logical addresses of modules in a device. All the modules like Pump Motor Controller, Power Supply Controller, Communication Engine, User Interface Controller, etc., have a unique ID so that they can be uniquely identified in a pump. The protocol stack can support 254 modules as the address field is 1 Byte field and logical addresses 00, 01, and FF are reserved addresses. If modules are identified according to their unique hardware address (MAC addresses), and as the hardware addresses are more than a Byte in size, this would add overhead to the protocol. To avoid this, each module may be assigned a logical address between 1 to 255 and this layer then maintains the assigned addresses. The application layer does not need to know what the hardware address is or what the logical address is in general, which simplifies logical and API calls.


One of the modules is generally assigned with the task of generating unique logical addresses for other modules in the device, no matter if those modules are connected directly to this special module or not. When the device powers on, all the modules power on as programmed. The module responsible for generating address for devices is called the “root” device. The root device is aware of its special role and assigns itself a logical address of 01. As other modules wake up, they assume their logical address as 00. They know that 00 is not a valid address but also know that there exists a module with address 01 who can provide a unique address to them.


Hence, these modules send address requests to a destination with address 01. On receipt of this message, the root module checks its internal table to verify if the requesting hardware already has a logical address assigned. If a logical address is assigned, the root module sends that same logical address in response; else it generates a unique logical address, updates this address in its internal table against the requester's MAC address and sends this address in response. On receipt of an Address Response, the requester module starts communicating with this logical address.


A module in one or more embodiments may not communicate without a valid logical address. If multiple modules try to request for a logical address, there will be collisions. Due to collisions, no requests ever reach the root module, and thus none of the modules receives a logical address. In this scenario, other modules will retry after a random period of time. Depending on the criticality of device, the amount of random time can be varied, i.e. critical devices may wait for lesser period of time before a retry. The amount of wait time may be part of configuration and the devices may wait with reference to their internal clock for example.


If a device does not desire to use the dynamic addressing mechanism, each module may be programmed with a unique address, for example to implement a static versus dynamic address assignment scheme. Embodiments may still utilize a root module that maintains the addresses of the connected modules.


Embodiments of the data link layer may also implement routing. As mentioned, a module may have multiple bus types or topologies and there may be different type of devices connected on various buses. If a Data Link layer receives a packet that is not addressed to it, it first checks if it has multiple bus architectures and if true, it forwards the message to other buses; else it simply discards the packet. This kind of addressing mechanism is well suited for star topology for example. Hence if PMC1 wants to send data to PMC2 but there is no direct data path, then it will re-route it through the root module. In this case, the root module can broadcast the message in the network or perform a lookup in its internal table and just forward the packet on a specific line. Hence, in one or more embodiments that implement routing, each module that supports multiple communication buses may maintain a list of all devices directly connected to the module so that they can efficiently route the packets. As stack supports data routing, it seamlessly bridges multiple heterogeneous data buses, thus making communication, bus topology independent. Few examples of possible bus topologies include Ring, Star, Mesh, and Tree topologies or any other topology that may be utilized to transfer data.



FIG. 3 illustrates an embodiment of an address request method implemented within the manager layer. As shown, when a device is added to the system, for example hot-swapped in, the device boots and requests an address from the root device. The new device waits for a response and if a timeout occurs, requests an address again. Once the root device receives the address request message, it looks up an available device number and generates a logical address for the new device and updates the table. Alternatively, if there are no available numbers left a NAK with appropriate error message may be returned to the new device. The root device returns the new device logical address to the new device in an address response message. Any further requests for the address are handled by lookup via the root device. The new device stores the logical address in a local table for further use. This capability generally does not exist in medical devices or infusion pumps since the configurations are generally assumed to be fixed, using a fixed operating system and fixed bus without regard to potential new devices and new types of devices that may communicate with a root device.



FIG. 4 illustrates an embodiment of a simple infusion sequence utilizing various messages provided by embodiments of the method. Once the address of a new device is obtained, it may communicate with the other components within the system. The figure shows user interface controller UIC having device number 1, initially connecting to a drug infusion pump having device number 3, wherein the logical addresses of the devices, or device numbers are obtained as shown in FIG. 3. The UIC accepts input from a Care Giver that indicates an infusion is to take place. The UIC application calculates the necessary steps to achieve the infusion and sends an infusion header and data message to the drug infusion pump, which acknowledges the message. The UIC then sends an infusion safety data message, which is acknowledged and after the infusion is complete, the UIC sends an infusion stop data message, which is acknowledged. This scenario is a typical scenario that enables any type of drug infusion pump to be added to a system and utilized, for example in a hot swap scenario where an infusion pump may return an error or a different type of drug infusion pump is to be added to the system and utilized for example.



FIG. 5 illustrates an embodiment of a connection method implemented within the session layer. In the scenario shown, the UIC requests a connection in order to communicate with the PMC to command the PMC and/or for example obtain status updates. In this case, PMC acts as a service provider as the PMC is providing status updates on a known port. UIC sends a connection request to PMC on that port, e.g., port 10, shown as a message passing from left to right. After receipt of the connection request, the PMC accepts the request, generates a unique CID, e.g., 26 for this communication and updates its internal table. The PMC sends the generated CID back to UIC as a part of connection accept message, shown traveling from right to left. On receipt of connection accept message from the PMC, the UIC extracts the CID from the message and updates its internal CID table as shown in the lower left. The UIC then sends an acknowledgement message to the PMC to confirm the successful receipt of CID. If the PMC is not able to process the request from UIC and hence cannot establish communication, the PMC sends a connection reject message to the UIC. On receipt of connection reject message, the UIC may retry to obtain a connection. See also FIGS. 10A-D, 11A-B and 12A-B for an embodiment of the exemplary message structures that may be utilized to form an implementation of various layers, which are described further in detail below.



FIG. 6 illustrates an embodiment of a data exchange method implemented within the session layer. Once the PMC receives acknowledgement from the UIC, the connection process is complete. At this time, both devices may exchange data using the agreed CID. When the session layer of PMC receives any data from the UIC with a valid CID, it performs a lookup in its internal table against the ‘Destination ID’ and ‘CID’ to resolve the port number where the packet is to be forwarded.



FIG. 7 illustrates an embodiment of a disconnection request method implemented within the session layer. On completion of data transmission, either of the communicating parties may request for a connection termination. As shown, the UIC initiates the process of connection termination. It sends a disconnect request to PMC with the respective CID. The PMC processes the request and if there is no active communication, the PMC will send an acknowledgement to the UIC and delete the CID entry from its table. On receipt of disconnection acknowledgement from PMC, the UIC also removes the CID entries from its table.


Although the general session layer communication protocol has been described above, a more in-depth description of the Session layer messages follows, according to one or more embodiments of the invention. The message structures utilized in one or more embodiments of the invention as described below are shown in FIGS. 10B-D.


Connection Request Message


For a connection-oriented communication session, when an application opens a socket to communicate over a port on some other device, a handshake is performed before the communication starts. The handshake begins with a connection request type message to the service provider. The “layer flag” is set for this message type. Therefore, the request packet is consumed by the session layer. The connection type may be initially set to “Unknown” suggesting that the data packet is neither connection-oriented nor connectionless. The message type is set to “Connection” as the command is used to establish new connection. The message is a request for establishing new connection; hence “Command” field has “Connection Request” set. The application requesting a connection specifies the destination's port address and also provides its own port address, hence the connection request packet has source and destination port address.


Connect Accept Message


On receipt of a connection request message, if the service provider has enough resource, it responds with a connection accept type of message. The service provider generates a CID for the communication and sends it to the requester as a part of this message. As the connection requesting entity has no information of the generated CID, the service provider sends source and destination port address as a part of this message to let the other end know about the generated CID.


Connection Acknowledgement Message


On receipt of a connection accept message, the requesting end updates its internal table with the received CID. In response to connection accept message, the requesting end sends an acknowledgement message to indicate the service provider about the receipt of CID and complete the handshake. It is possible that multiple applications on one module request to communicate with one application on another module on the same port number, e.g., many-to-one. To inform the service provider about the particular application that is sending an acknowledgement, “source port” is added to the acknowledgement message.


Connection Disconnect Message


Once the communication is completed, any one of the participating entities may request a connection disconnect for a graceful termination of the connection.


Connection Disconnect Acknowledgement Message


This message is sent as an acknowledgement on receipt of a disconnect message. The message is intended to ensure that a communication is not terminated if an active connection still exists. If a disconnection acknowledgement is not received within a certain time period, a disconnection attempt may be made again.


Connection Reject Message


If the service provider cannot accept any new connections, it sends a connection reject in response to a connection request message. In the connection reject message, it sends the reason for rejecting the request. On receipt of a connection reject message, the requester may retry after some time for example.


CID Info Request Message


Any participant involved in communication can request for status of CID. This message acts as a ping message to verify if the destination port is open and CID is an active CID.


CID Info Response Message


On receipt of a CID Info request, a CID Info Response is transmitted. This message contains the source and destination port addresses involved in communication, window size for transmission, etc., and also indicates if the CID is active or not.


Socket Status Request Message


This message is utilized to request socket related information such as the type of socket, purpose of opening this socket, etc.


Socket Status Response Message


This message is sent in response to Socket Status Request message. The message contains socket related information such as the type of socket, purpose of opening this socket etc.


Subscribe to Service Message


The communication protocol enables applications to provide a service, e.g. a broadcast service. For example, the PMC may have a service running that broadcasts PMC status periodically on a known port. If the UIC requests the PMC status, it may simply subscribe to this service with the PMC and receive the messages. Typically these services are one-way communication.


Subscribe to Service Acknowledgement Message


Once the service provider receives a subscription request, it has to provide a CID to the requester. The CID is delivered through an acknowledgement message.


Unsubscribe from Service Message


If a subscribed application no longer desires to be subscribed to a service, it may request to unsubscribe. On receipt of an unsubscribe service message, the service provider removes the entries from its internal CID table and sends an acknowledgement to the requester. If the service provider finds that there is no one subscribed to a service, it may decide to stop the broadcast service until it has at least one subscribed application.


Unsubscribe from Service Acknowledgement Message


On receipt of this message the application requesting to unsubscribe, removes entries of CID from its internal table and releases the involved sockets and ports.


Device Address Request Message


An application may request a logical address for a device using this message.


Device Address Response Message


On receipt of an “Address Request” message, a device sends its address as a part of the response message. Alternatively, a Device Address Response Message may be sent independently at anytime and may not necessarily be tied to a request message.


Device Type Request Message


This message is used to request name of a device. Every connected device has a unique address but may have non-unique names or no names. Device types can be PMC, CE, UIC, etc.


Device Type Response


This message is generally sent in response to “Device Type Request” message and contains the type of the device sending this message. Alternatively, a Device Type Response Message may be sent independently at anytime and may not necessarily be tied to a request message.


Connection-Oriented Data Message


At least one embodiment of the session layer adds just two bytes of header information when sending data between devices. The CID is generated and exchanged during the handshake process prior to data transfer.


Connectionless Data Message


Connectionless data transfer is used when no handshake is required to transfer data. As there is no handshake, there is no CID generated for the communication and hence both source and destination port numbers are utilized to ensure the delivery of data.



FIGS. 11A-B and 12A-B illustrate corresponding message structures for exemplary embodiments of the Transport layer and Data Link layer respectively and are described further below.



FIG. 8 illustrates a layer flow diagram that shows the flow of data within the various layers implemented in at least one embodiment of the invention. Specifically, data flow up the protocol stack for incoming data is shown. The destination application buffer location is not known until the data frame moves up to manager layer. Hence, the fragment is stored in a memory pool until it reaches manager layer and once the target application is resolved, the data is copied from the memory pool into application buffer. In one or more embodiments, memory utilization may be minimized by returning a buffer to memory if the buffer is over a predefined age threshold.


Data Link Layer


Data Link layer controls one or more physical communications links, data buses. The layer filters the messages directed to the specific device and ignores other messages. The layer may compute a CRC on the received packet and verify it with the received CRC. Valid data frames are copied into a memory pool and pointer to these messages are forwarded to the transport layer.


The transport lower layer and data link layer run as an independent service and stores data in the designated priority queue, P1, P2, P3 or P4. The transport upper layer, session and manager layers execute in the application space, and the transport upper layer maintains pointers to the priority queues and Communication ID tables. In one or more embodiments, the memory pool, priority queues and CID tables are in shared memory space.


In one or more embodiments, the data link layer is further divided into two sub-layers, a link layer and a MAC layer. The MAC layer may interface with bus drivers and has a buffer for each underlying bus. As the data arrives on these buses, the data is copied into these buffers and then forwarded to link layer. The buffer may be implemented as a pair of buffers, while one buffer is used for receiving new data, other buffer is used to transfer previously received data.


The link layer copies the data from buffers into the memory pool. The memory pool is a contiguous memory block and each memory block may be implemented as a factor of frame length. As the application consumes data, the data is removed from the memory pool to make room for new data packets. As the application consumes data randomly, there may be memory holes in the memory pool. Hence, the link layer generally maintains a list of available memory locations in the memory pool. When memory is freed from the memory pool, the pointer to available location is added at the end of this list. When a new packet arrives, it is placed at the memory pointed by the first element in this list. If there is no element in the list, memory pool will be considered full and the packets will be dropped. In one or more embodiments of the invention a memory manager may be utilized to control access to memory from the various layers, including concurrent access control of memory from the various layers. Embodiments of the invention may minimize or altogether avoid multiple copying operations by maintaining one copy of data in the memory pool while passing pointers to the memory as the data moves up and down the stack. By controlling access to the memory during access, semaphores may be utilized to ensure data integrity while allowing multiple processes to effectively utilize the data in a concurrent manner. Avoiding multiple copy operations enables minimal memory utilization in embedded environments and minimizes processor utilization as well.


As the transmitter has tendencies to push data on buses, they can soon over-utilize the bus by transmitting too much data. The bus driver at the MAC layer in one or more embodiments may be implemented to handle such scenarios.


Transport Layer


In one or more embodiments, the transport layer may be divided into two sub-layers, a transport upper and a transport lower layer. The transport upper layer resides in application space whereas the transport lower layer resides in kernel space. These two layers together handle transport layer functionalities.


The transport layer is implemented in one or more embodiments to reassemble fragmented data and also to resolve data priority. When a new data packet is received by transport lower layer, a timer may be started for the data. If the data is not consumed before the timer expires, the data may be discarded and the memory freed from the memory pool. This avoids memory starvation if no application exists to consume received data. If the acknowledgement field was set, the transport layer sends a NAK, “timed out in priority queue” error code, for example.


The transport layer header has an acknowledgement flag and if the flag is set, the receiving transport layer will have to send some kind of acknowledgement for the received data fragment. If fragmented data is received, the acknowledgement is sent after receiving window size amount of data or a complete message. This flag is set for a connection-oriented data transfer to ensure delivery of data. This flag may also be set in a connectionless data transfer only if data fragmentation is utilized.


Fragmented Data Packet Handling


In case of fragmented data, before the transmitter starts sending any data fragments, the transport upper layer at the transmitter first requests a window size from the receiver. The window size may be exchanged once during first data transfer or may be obtained before every data transfer. Window size is the number of data fragments that can be sent before an acknowledgement can be expected. When receiver receives a window size request, transport upper layer at receivers end, computes the amount of free memory in application buffer and sends the response as window size in the ‘window size response’ message.


In one or more embodiments, the transport upper layer at the transmitter side initializes a data structure for the CID that requested a window size. In this structure, the transport layer stores the CID, last reported window size, last successfully received fragment number and the maximum allowed time period between two fragments, etc. Also, the transport upper layer at the receiver maintains same structure. The transport layer expects that the fragments will be sequentially numbered starting from 1 in one or more embodiments.


As the transmitter receives a window message, it calculates the number of fragments to be transmitted before expecting an acknowledgement. The transmitter starts sending data fragments in sequence starting from fragment number 1 for example.


When the receiver receives first fragment, the transport lower layer starts a timer on the received data frame and places the fragment it into the respective priority queue. The transport upper layer updates the structure and stores the sequence number of the fragment. If the fragment is delivered to the application buffer by upper layers, the upper layers inform the transport upper layer about the success. The transport upper layer updates its structure with the first fragment being delivered. Upper layers do not inform application about the available fragment until all the fragments constituting to a message are received. An application buffer is used for re-assembly of fragments to minimize memory footprint.


If the transport upper layer receives all the fragments for a window successfully, it waits for all the fragments to be delivered to application buffer successfully. Once all the fragments are sent to application buffer, the received fragment number and delivered fragment number match and the transport upper layer sends an acknowledgement for the last fragment in the sequence. The transmitter receives the acknowledgement at the transport upper layer.


Ideally, the transport layer accumulates all fragments, verifies that they are in sequence and merges them into one complete message before sending it up the stack. However, in one or more embodiments, the transport upper layer forwards the frames to the session layer as they are received, but ensures that the fragments are delivered in sequence. This optional implementation may be utilized to lower memory utilization. This is the case since the message does not have to be reconstructed in full within the stack until the full message is received in the application. As the fragment number in the transport header is 10 bits wide in one or more embodiments, the layer can support a maximum of 1023 fragments (fragment number 0 is reserved and represents a non fragment data frame) before the fragment numbering overflow. As each fragment has a maximum of 248 Bytes payload, hence a total of 253,704 Bytes is required at the receiver end for each active connection to accommodate all the fragments. Any other size of fragment number field may be utilized to increase the overall size as one skilled in the art will recognize.


At the receiver, as the fragments are received, transport upper layer updates the last fragment number in its structure. Before updating, it verifies that the received fragment is in sequence with previously received fragment. If it detects a missing fragment, the layer still forwards the fragments up the stack, but in their respective token puts an offset value. Metadata along with a pointer to the received data fragment is called a token. This offset value is used by manager layer to provide a gap while accommodating other fragments around the missing one, so that the gap can be filled once the missing fragment is received. For example to create an empty space in memory so that when the missing frame is finally received, it will be accommodated in this empty space to complete the final message. Meanwhile, transport upper layer waits for the fragments to arrive and then looks for any missing fragment in the sequence. Once the layer generates a list of all missing fragments, it requests for retransmission of fragments from the transmitter. Once the missing fragments are received, they are forwarded to upper layers so that they can be used for filling the empty spaces in final message.


When retransmission is required, transport upper layer at receiver end, sends retransmission request message with the desired fragment number in it. The receiving end maintains a list of missing fragments and as the missing fragments are received, their entry is removed from this list.


If the transmitter retransmits an already transmitted fragment, the receiver compares the fragment number with last received fragment number and will detect that there has been a retransmission. The layer checks if the retransmission was requested by the receiver explicitly or not. If the retransmission was intentional, the fragment is consumed else the fragment is dropped assuming a false retransmission of data.


Once the transmitter sends one window size worth of fragments, it starts a timer and waits for an acknowledgement on the last fragment in the sequence. The transmitter may send any further fragments only when it receives an acknowledgement. If the acknowledgement is delayed and the timer expires, the transmitter may send a “window size” request message before retransmitting the fragments. A receiver may fail to send an acknowledgement if the receiver is too busy or its buffers are full. Hence, a “window size” message is sent because it serves two purposes, the first being that a response to this message implies that the receiver is ready for accepting messages, and the second being that the new responded window size buffer is available at receiver so that chances of getting an acknowledgement increases.


In case of missing fragments, the receiver sends a retransmission request instead of an acknowledgement. A retransmission request can only be sent if the last fragment in the sequence was either received successfully or was found missing. Hence, the transmitter considers a retransmission request message as an implied acknowledgement and no more waits for an explicit acknowledgement, but may wait on acknowledgement for retransmitted fragment.


Missing fragments can be of three types, the first fragment missing, any fragment(s) missing between first and the last fragment of a complete message, and the last fragment itself missing. If the first fragment is missing and the receiver starts receiving from fragment number 2, it accumulates all the messages till it receives window size messages and explicitly requests for the 1st fragment. The same technique is used for requesting any missing fragment between 1st and last fragment.


Missing the last fragment of a complete message may be a complicated scenario because transmitter never informs the receiver about total number of fragments needed to send a message and hence, there is no way for receiver to know when the message completes. Missing “last” fragments can be of two types, missing the last fragment from a window and missing the last fragment of a message. In the case of missing the last fragment from a window, it is easy to detect. Every time a fragment is received, the receiver starts a timer and waits for next fragment to be receive before the timer expires. The transmitter sends the last message for the window and waits for an acknowledgement. If this message is lost, the receiver waits for this last fragment to arrive. The timer at the receiver expires earlier than the timer at the transmitter. As the receiver keeps track of fragment sequences and window size, it realizes that the last fragment was not received on time and hence sends a retransmission request for the last fragment.


A more difficult problem occurs when the last fragment of a message is lost. As the receiver has no idea about how many fragments will constitute a message, it looks for the fragment with ‘last fragment’ flag set. This fragment indicates the receiver that it was the last fragment from the message. If this fragment is lost, the receiver has no idea when to stop reassembling fragments. To ensure delivery of this last fragment, the transmitter can use following two approaches.


In the first approach, the transmitter knows that the last fragment is approaching. It explicitly reduces the window size to make sure that the last fragment of the message becomes the last fragment of the window as well. As the receiver can detect the last fragment from a window, if the last fragment from a message is lost, the receiver may request retransmission.


In the second approach, the transmitter will send the last fragment with ‘last fragment’ flag set, followed by few fragments with random payload but with incremental fragment number. If the last fragment of the message is missing, the receiver will detect the missing fragment as there will be gap in sequence numbers and will request for retransmission. When the receiver attempts to arrange the fragments in sequence, it detects the fragment with ‘last fragment’ flag set and hence discards all fragments following this fragment.


Non-Fragmented Data Packet Handling


For a non-fragmented data frame, it is first received by transport lower layer, which starts a lifetime timer on this frame and puts the frame in appropriate priority queue. The frame is picked from the priority queue by transport upper layer, which forwards it to other layers, for example Session layer.


Session Layer


Session layer major responsibilities are to ensure application-to-application delivery of data and generate unique CID's within a system. The stack works on the principle of service provider and service consumer. The application providing service generates unique CID's for the engaged participants. The CID is unique within the system running the service provider application in one or more embodiments. The CID may be thought of as a key used to hide the information about source and destination ports engaged in communication.


The session layer may be implemented in a lightweight or a very thin layer to a connectionless communication because a connectionless data packet will contain the source and destination port addresses as part of their headers and hence does not utilize a CID.


Packets reaching the session layer may be divided into two categories, namely data and control. Further, the incoming data can be connection-oriented or connectionless and fragmented or non-fragmented.


Connection-Oriented Data Transfer


Connection-oriented data transfer makes use of a connection through a handshake process. After an initial handshake process is complete as is described further below, data exchange occurs. In connection-oriented data transfer, embodiments of the invention utilize a data header with an acknowledgement flag set and connection type set to 01, for example. Data being exchanged may be fragmented or non-fragmented based on the size of the data and the underlying packet size supported by the physical medium.


Fragmented Data


When an application writes to a virtual port, the session layer adds a session layer header to the data and forwards it down the stack. In one or more embodiments, the session layer header is 2 bytes wide. Hence, if fragmentation is needed at the transport layer, the first fragment is set to contain the CID from the session layer while the rest of the fragments may contain only application data. The session layer at the receiving end forwards the first fragment that contains the session layer header, but is unsure as to where to forward other fragments from the sequence as there is no CID information in subsequent headers. Also, if two or more applications on one device want to send data to one device, it is not possible without further information in general at the receiving end to aggregate fragmented data because there is no way to uniquely identify which application is sending what data fragment. To resolve this issue, the transport layer copies session layer header to all the related fragments. As all the fragments will now contain CID, they can be uniquely identified at the receiving end.


The session layer header contains an acknowledgement flag that is utilized in the case of complete messages. As the session layer ensures application-to-application delivery of data, it sets the acknowledgement flag for the receiver to acknowledge successful delivery of data. As the header is copied in each fragment, the session layer will look at the flag and will acknowledge the transmitter every time a fragment is delivered which is not what acknowledgements are generally for, i.e., a complete message acknowledgement.


To avoid this issue, the transport upper layer at the receiver end appends metadata to packets as they are sent up the stack. Metadata along with pointer to received data fragment is called a token and instead of passing data, transport layer passes a token to session layer. In the case of exceptions in behavior of the session layer, metadata provides guidelines for the session layer to follow. For example, the session layer will not send any acknowledgements for data fragments, and when the transport upper layer receives a fragment with a “last fragment” flag set, it updates the metadata so that session layer knows that it needs to send an acknowledgement to the transmitter regarding the receipt of a complete message.


Flow of Control


As the fragments move through the session layer, session layer extracts the CID from the fragments, performs a lookup in the Communication ID table based on CID and the sources logical address obtained from the metadata. The session layer determines the associated file descriptor source and destination ports for the CID. Once the file descriptor is known, it removes all the headers and modifies the metadata to communicate the file descriptor detail to manager layer.


Once the fragment arrives at the manager layer, the manager layer extracts the file descriptor information from metadata and forwards the fragment to respective application. Before the manager layer forwards the message to the application, it determines if the file descriptor is still in use and in the state of accepting data. If conditions are favorable, the message is copied into the application buffer and a “message received” flag in file descriptor is set. If the current operation on the file descriptor is a blocking read, the read function call returns with number of bytes available in application buffer. If the current operation is a non blocking call, the application either checks the flag and if set, reads data from buffer, or the manager layer may make an asynchronous function call on receiving data.


After delivering the data to the application, the manager layer returns the token to session layer. This token contains information about the state of the previously passed message. Depending on the state of token, the session layer performs activities such as sending a session-to-session layer acknowledgement.


If the data is fragmented, session layer further modifies this token and sends it down to transport layer, otherwise the session layer consumes the token. The transport layer determines if the fragments were delivered in sequence they were sent and accordingly controls acknowledgements and window sizes.


Non-Fragmented Data


If a message size is less than the Maximum Transmission Unit (MTU), no fragmentation is required and the complete message is sent in one frame. As the frame moves up the stack, transport upper layer adds very little information to the metadata as complete information for the session layer is already available in the frames header. The session layer reads the header and extracts the data type. If the data type is connection-oriented data, the session layer extracts the CID and performs a lookup in the CID table to determine source and destination ports. The session layer removes all the headers from the datagram, updates the metadata with the destination file descriptor, and forwards it to the manager layer.


Connectionless Data Transfer


As mentioned above, in a connectionless data transfer, the session layer may be implemented in a lightweight or very thin layer. As connectionless data transfer does not utilize a handshake, no CID is generated. Due to the absence of the CID, the protocol header utilizes source and destination port addresses. The session layer reads the destination port address and determines the associated file descriptor and forwards the message to that port. As connectionless data transmission does not guarantee delivery of data, the acknowledgement flag on the frames is set to false.


If a connectionless data frame is larger than the MTU, the transport upper layer fragments the data into manageable sizes without setting the transport layer acknowledgement flag as would be done in connection based communications. During reassembly, if transport layer sees any missing fragments, it discards the complete message. Through a token, the transport layer informs upper layers to discard previously accumulated fragments in application buffer.


Manager Layer


Manager layer handles file descriptors and forwards packets from lower layers to appropriate file handlers. The manager layer also performs the copying of data from the memory pool into the application buffer. The manager layer knows the size of the application buffer and the application buffer size may be smaller than one frame length.


If the application buffer is large enough, the manager layer copies the complete message into application buffer. If the application buffer is not large enough, the manager layer copies data in a sequential manner. The manager layer fills the application buffer with data and waits for the application to read the data before copying the next portion of data. Once data is successfully delivered to the application, depending on the token, the manager layer informs the session layer regarding success.


Control Flow Up the Stack


The flow of control is now described as data moves up the stack from the lowest layer to the application layer.


Data Link Layer


The data link layer control is described with respect to the two sub-layers that make up the data link layer, namely the link layer and the MAC layer. The MAC layer controls the physical bus drivers.


MAC Layer


As the datagram arrives on the physical bus, the bus driver copies the datagram into a buffer. Once the complete datagram is available in the buffer, the MAC layer calls an API in Link Layer to copy the available data into the memory pool.


The link layer API returns a value to indicate the outcome of the copy operation. The operation may succeed or fail. The returned error code provides the reason for any failure. The MAC layer waits for the API to finish the operation before storing newly available data into the buffer.


Link Layer


As discussed in the sections above, the memory pool may be fragmented due to applications consuming data at random rates, resulting in holes in the memory pool. In one or more embodiments, the link layer maintains a link list, or a doubly link list, or bit map or any other data structure capable of storing available memory locations in the memory pool. When a memory location is made available, a pointer to the memory location is added to the tail of the list. When a new datagram is available, it gets copied at the memory pointed by pointer in the head of the list. Though the received message can be of any size and wherein a maximum size exists, for example 256 bytes, the size of the memory pool is selected to be an integral multiple of the maximum datagram size. This simplifies memory management, as the stack is aware of the size of allocated memory given the pointer to that memory. There may be instances when a datagram is available at the time when memory is made available in the memory pool. In this case, both the copy and the delete processes will try to access the list simultaneously leading to concurrency issues. In one or more embodiments, the memory pool may include non-uniform size buffers for a more flexible buffer implementation at the cost of memory management complexity as one skilled in the art will recognize.


When the MAC layer calls an API to copy the data from hardware buffer to memory pool, the API first checks the list for any available memory location in the pool. If memory is available, the API copies the datagram to the memory location pointed by the head of the list and deletes the pointer from the list. If no space is available, for example the link list is empty, or error occurs during the copying to memory pool, the API returns respective error code.


After successfully copying the datagram, the API adds the pointer to the datagram in a list with a number of timer ticks remaining before the data should be delivered to application. This API may be reentrant as the MAC layer may be riding over multiple bus architectures and the data may be available in multiple buffers at the same time resulting in calling this API while the layer is still servicing the previous call.


The protocol stack may be implemented with a time limit within which a datagram is to be used by an application, or else the datagram is dropped from the memory pool. To enable this feature, embodiments may implement a global list containing pointers to each datagram with the timer count on each pointer. As the new packets arrive, an API adds the pointer to this packet at the end of this list. The API adds “time to live” value to the current timer count and generates a timer count that represents an expiration time for the packets. When timer count changes, an API looks at the timer count starting from top most element in the list and starts deleting datagram if their timer counts are less than or equal to current timer count.


Once the data is consumed by the application or the data times out, an API is called to remove the datagram from the memory pool and add the pointer to the available memory list. This API may be reentrant as the data may expire at the same time it was consumed by the application. Both processes may attempt to delete the same datagram, therefore semaphores/locks may be utilized to effectively serialize control.


When data gets copied to memory pool, the link layer generates a token for the packet. The token contains the pointer to the datagram and length of the datagram. This token is forwarded to the transport layer through a transport layer API for further processing.


Transport Layer


After the transport lower layer receives a token, the transport lower layer determines if the frame is a transport-layer-to-transport layer message. If the ‘layer flag’ is set, then these types of messages are layer-to-layer messages and hence are not forwarded to upper layers. If the flag is not set, transport lower layer looks at the priority of the message and places the token into appropriate priority queue.


In one or more embodiments, the transport upper layer receives the token from the priority queue and determines if the ‘extended flag’ is set or not. If the flag is set, it indicates that a large volume of data is to be expected and informs the API that an extra byte has been used in header for sequencing large number of fragments.


The layer also reads the “Last Fragment” flag. A set ‘last fragment’ flag indicates to the layer that the current datagram fragment is the last fragment in the sequence of fragments and hence the end of one message. If there is any fragmentation, at least one fragment will have this flag set.


The layer further reads the acknowledgement flag. If the transmitter requests or otherwise is to be sent an acknowledgement for delivery of the datagram to the receiver's transport layer, the layer will set this flag and the receiver will acknowledge the receipt of the packet. If the devices engaged in communication have agreed on a window size for acknowledgements, then the transport layer acknowledges after receiving window size messages else the layer acknowledges each datagram.


The transport upper layer adds more information to the data token and forwards it to session layer. The transport upper layer informs the session layer if the message is a complete message or not. In case of fragmented message, the transport layer informs the session layer about receiving the last fragment, so that session layer may send an acknowledgement if needed.


Session Layer


From the data pointer in the token, the session layer accesses the frame and extracts session layer header. From the header, session layer first determines if the message is a layer-to-layer message or needs to be forwarded up the stack. If the message is a layer-to-layer type message, then the message is consumed by session layer.


If the layer flag is not set, the frame is forwarded up the stack. The session layer reads the ‘Connection Type’ field and determines if the message is of unknown connection type or connection-oriented or connectionless. An unknown connection type is generally for the messages exchanged during handshake process, whereas a connectionless message does not need an acknowledgement for delivery, and connection-oriented messages are the ones that use an acknowledgement on successfully delivery.


The session layer further looks into the message type field to determine the type of frame. The frame type is used to determine the purpose of the frame, and only ‘Data’ type frames are forwarded up the stack and the control type frames are consumed at session layer.


The CID is generated by the application providing a service. Any application that wants to use the service will request a communication ID. CID is unique within one module, for example all of the CID's generated by the UIC are unique within a particular UIC. The CID is generated through a handshake process, where the application using the service sends the details required for uniquely identifying an active connection and receives the CID in response.


The CID specifics and details may be stored in a CID table located in a shared memory region in one or more embodiments, so that the session layers of all the applications may access the CID. In a connectionless data frame, there is no CID information as there is no handshake utilized to establish a connection. Hence connectionless frames contain both source and destination port address in the header.


In a connection-oriented data transfer, there exists a CID in the session layer header. Once the session layer determines the CID from the header, the layer combines the information with the source logical address available in the data token to uniquely identify an entry in CID table. From this table, the session layer determines the source and destination port address and the file descriptors handling the port. The source logical address of the received frame is set by the data link layer along with the file handler information and is forwarded in the data token to the manager layer.


If the received frame is connection-oriented and is a complete message, the session layer maintains a record of the message and forwards the data token to the manager layer. Once the manager layer copies the frame from memory pool into the application buffer, the manager layer notifies the session layer about the successful delivery of data. On receipt of notification, the session layer sends an acknowledgement to the transmitter session layer regarding the successful delivery of data. If the delivery was unsuccessful, as a part of the acknowledgement, the session layer forwards the error message returned from the manager layer to the transmitter.


Manager Layer


The session layer calls an API in manager layer and passes the data token to the manager layer. The manager layer copies the data from memory pool into the application buffer and notifies the session layer regarding the copy. The manager layer notifies the lower layer about the delivery of message by modifying the data token and sending the data token back to the session layer. Once the data is successfully copied, the manager layer removes the frame pointer from the list of frames monitored by the timer and deletes the frame from the memory pool to make room for new packets.


It may happen that the application buffer is smaller in size than the received data frame, in such cases the manager layer will fill the application buffer with what it can hold and wait for the application to consume it. Once the application consumes the message, the remaining portion of the message is copied and the process is repeated until the complete frame is consumed. Before starting the progress of copying messages in small sizes, the manager layer removes the pointer to the frame from the timer-monitored list because the timer may expire and corrupt the message. Also, the manager layer notifies the lower layer regarding successful delivery of data only when a complete message is sent to the application. At the end of the sequential copy process, the manager layer deletes the frame from the memory pool.


In the case of fragmented data, as the fragments are received by this layer, it copies the fragments into the application buffer and notifies the session layer. The session layer forwards the notification to the transport layer. The transport layer, after receiving notifications for a window size number of messages, sends an acknowledgement to the transmitter about receiving the messages. When the last fragment is successfully delivered to the application, it implies that one complete message was delivered. In such cases, the manager layer notifies the session layer of success, and the session layer sends an acknowledgement message to the transmitter regarding the success, thus providing guaranteed delivery of data.


Data Flow Down the Stack


Assuming that in case of a connection-oriented data transfer, the handshake process has already been done and a valid CID has been already generated, the application copies data into an application buffer and passes a pointer to the API exposed by the manager layer for sending data over virtual ports. The application also specifies the file descriptor that handles the communication and the size of data to be written on the virtual port.


The priority of a message is determined by the priority of the virtual port being used or priority can be set for the message passing through. Hence, through a set of API's, the manager layer informs the session layer about the priority of data, size of data, file descriptor for the communication, pointer to application buffer, and if data is connection-oriented or connectionless. If the data is connectionless, the session layer looks into the file descriptor table and determines the port number associated with the file descriptor. The session layer then adds source and destination port addresses as header to the data. If the transfer is to be connection-oriented, the session layer performs a lookup in the CID table and determines CID associated with the file descriptor and adds this CID as header to the data. The session layer then forwards this pointer to the transport layer and waits for an acknowledgement from the receiver.


The transport upper layer determines the size of the data and determines if fragmentation is required or not. If fragmentation is needed, the transport upper layer breaks the data into manageable sizes and adds information to the header so that the data can be reassembled at the receiver's transport upper layer. If fragmentation is not needed, the transport upper layer still adds some information in one or more embodiments. For example, the transport upper layer copies the data from application buffer into transmitter memory pool and depending on the priority of data, stores the pointer into appropriate message queues.


The transport lower layer eventually reads the pointer from the priority queue and forwards it to the link layer. The link layer determines the destination logical address and adds it to the data header, computes a CRC on the frame and adds it to the frame before sending it. The MAC layer determines the bus over which the destination is available and sends the data over that bus.


Flow of Data Up the Stack


As the data frame arrives at the underlying bus, the MAC layer determines if the frame is for the subsystem or for some other subsystem. If it is for some other subsystem, the MAC layer drops the data frame. The MAC layer copies valid data frames into a shared memory region and calls an API in the Link layer to inform it about arrival of new data. Throughout the stack, only the pointer to this data is updated to reduce multiple copying of fragments.


The link layer computes the CRC on the received frame and compares the computed CRC with the CRC on the received frame. Frames with invalid CRC's are dropped. Pointers to valid frames are forwarded to the transport lower layer.


The transport lower layer reads the priority of the frame and adds a pointer to the frame to the respective priority queue. The pointer to the frame remains in the queue and waits for appropriate application to consume it. Eventually, the target application's transport upper layer reads the pointer to the frame from the priority queue.


The transport upper layer looks at the headers to determine if the data is fragmented or a complete message. If the data is fragmented, the layer reassembles all the messages from the sequence and then forwards it to the application layer. If the data is not fragmented, it directly forwards the pointer to the frame to the session layer through appropriate API calls.


The session layer looks at the frame headers and determines if the message is of type connectionless or connection-oriented. If the message is connectionless, the session layer looks at the destination port number and determines the file descriptor handling that port. The session layer forwards the pointer to the manager layer with appropriate file descriptor information. If the frame is connection-oriented, the session layer reads the CID and determines the file handler handling that communication. The session layer then forwards the file descriptor information to the manager layer and waits for an acknowledgement from the manager layer. The manager layer sends an acknowledgement indicating whether the data was delivered to the application or not. This information is used by the session layer to acknowledge receipt of data.


The manager layer may be implemented with a lightweight or thin layer and is responsible for copying the data from the memory pool into the application buffer and freeing the memory pool. Once the data gets copied into the application memory, the manager layer informs the application about data being available. The manager layer sends an acknowledgement to the session layer. Thus, to the applications, the manager layer offers synchronous and asynchronous methods for reading and writing to virtual ports.



FIG. 9 illustrates an activity diagram showing routing between various devices. As shown, Device A is connected directly to Device B, which is directly connected to Device C. Device A is not directly connect to Device C. When Device A attempts to send a message to Device C, it sends the message out and Device B reads the message, determines that the message is not for the device and checks to see if there is a path to the device in Device B's destination table. If so, Device B forwards the message to Device C, which processes the data. Hence, embodiments of the invention enable routing and daisy chain or multi-bus configurations that are generally not as flexibly possible in medical devices such as infusion pumps.


An embodiment of the manager layer API is detailed below. The manager layer provides the API to enable socket programming over the protocol stack. The manager layer API calls are utilized by any application that wishes to transfer data using an embodiment of the invention.


pro_socket—creates an unbound socket in a communication domain, and returns a file descriptor that can be used in later function calls that operate on sockets.


int16 pro_socket (ConnectionType type, uint8 *pSocket)


Arguments:


type: specifies the type of socket to be created (CONNECTIONTYPE and CONNECTIONLESSTYPE for connection oriented and connection-less data exchange).


pSocket: integer pointer to return newly created socket.

















       typedef enum ConnType



{



   CONNECTIONTYPE=1,



   CONNECTIONLESSTYPE=2,



   RAWTYPE=3



} ConnectionType;










On successful completion, the function shall return a SUCCESS; else appropriate error code is returned. The API returns allocated socket in the reference variable pSocket passed as a parameter.


pro_bind—assigns a local address to a socket identified by file descriptor socket.


int16 pro_bind (uint8 uint8Socket, const ProSockaddr *pAddress)

















typedef struct pro_sockaddr



{



   uint8 address;



   uint8 portNo;



   uint8 priority;



   uint8 flags;



   uint32 timeout;



   datafilter *filter;



} ProSockaddr;










address: holds logical address of device


portNo: holds port number for connection


priority: holds the priority of the port. All the data passing through this port inherits ports priority


flags: holds configuration flags for changing behavior of socket


TIMEOUT: flag is set, waits for an operation to complete within a given period of time, else returns.


SO_LINGER: set flag indicates that a connection will be terminated only when all the data pending to be sent is sent successfully.


FILTER_DATA: set flag indicates that the data matching supplied filter pattern will only be forwarded to callback function registered to handle it. If flag is reset, data matching the filter will be sent to both, regular socket handler as well as to the registered callback function.


timeout: If the TIMEOUT flag is set, timeout value is specified here. A timeout value of 0 returns immediately.


filter: link list of datafilter type structure defining the filter to be applied on received data. More than one element in this link list will have an ORing property. As an example, if an application wants to process data either from PMC, or UIC, or CE or all three, it will create three nodes in this link list one for each PMC, UIC and CE.


Datafilter structure is used to allow applications to select what messages they want to receive, and which function should handle what type of messages. A regular expression pattern is used to create a filter on received data and once a match is found, data is forwarded to registered callback function.

















        typedef struct



{



        char *regEx;



        uint8 index;



        uint8 length;



        void *callback;



        datafilter *filter;



}datafilter;










regEx: pointer to regular expression to be used for matching.


index: location to start looking for match in the data section of received message. A ‘0’ in this field indicates that the match will start from the beginning.


length: staring from the provided index, indicates the length of data section to be considered for regular expression matching. If index contains ‘0’ and length contains ‘0’, match will be performed over the entire data section.


callback: function to be called in case of a successful match. If this field is set to null, all the matching data packets will be dropped depending on FILTER_DATA flag.


filter: linklist of any additional filter to be added over existing filter. If this filed is contains additional filters, on a successful match, callback is made to the function specified in the structure containing this linklist. This link list of filters has anding properties, i.e. a match is successful only if all the regEx specified in all the filters match. As an example, if an application wants to process data containing expressions PMC, UIC and CE, it will instantiate this filter for PMC and have a link list containing filters for UIC and CE respectively.


One or more embodiments support three priority levels for messages namely high, medium and low. The enum defining message priority is as follows.

















Typedef enum ProPriority



{



   HIGHPRIORITYTYPE = 1,



   MEDIUMPRIORITYTYPE = 2,



   LOWPRIORITYTYPE = 3



} MessagePriority;











Arguments:


uint8Socket: file descriptor of socket to be bound


pAddress: pointer to ProSockaddr struct containing address to be bound to the socket.


Return Value:


Upon successful completion, the function shall return SUCCESS, otherwise appropriate error code.


pro_connect—attempts to connect a socket to the specified address.


int16 pro_connect (uint8 uint8Socket, const ProSockaddr *pAddress)


Arguments:


uint8Socket: socket to be connected to specified address.


pAddress: pointer to structure pro_sockaddr containing peer address.


Return Value:


Upon successful completion, the function shall return SUCCESS; otherwise returns appropriate error code


pro_listen—marks the socket referred to by “socket” as a passive socket, that is, as a socket that will be used to accept incoming connection requests using accept( ).


int16 pro_listen (uint8 uint8Socket, uint8 uint8Backlog)


Arguments:


uint8Socket: file descriptor of a socket that needs to be put in accepting connections mode.


uint8Backlog: set a limit on number of outstanding connections in the socket's listen queue. A zero would set the queue length to system defined minimum queue length.


Return Value:


Upon successful completion, the function shall return SUCCESS; otherwise, appropriate error code is returned.


pro_accept—extracts the first connection on the queue of pending connections, creates a new connected socket with same socket type protocol and address family as the specified socket, and returns a new file descriptor for the socket.


int16 pro_accept (uint8 uint8Socket, ProSockaddr *pAddress, uint8 *pClientSocket)


Arguments:


uint8Socket: file descriptor associated with socket.


pAddress: Either a NULL pointer, or a pointer to ProSockaddr struct where the address of connecting socket shall be returned.


pClientSocket: pointer to an unsigned integer for returning file descriptor associated with the newly created socket.


Return Value:


Upon successful completion SUCCESS is returned along with an associated file descriptor for the newly created socket, on failure, returns appropriate error code.


pro_send—initiates transmission of a message from the specified socket to its peer. The pro_send( ) function sends a message when the socket is connected.


int16 pro_send (uint8 uint8Socket, const void *pBuffer, uint32 intLength, uint32 *pBytesSent)


Arguments:


uint8Socket: socket's file descriptor


pBuffer: points to buffer containing the message to send.


intLength: length of message in bytes.


pBytesSent: pointer to an integer for returning actual number of bytes sent.


Return Value:


Upon successful completion, the API returns SUCCESS else appropriate error code is returned.


pro_recv—receives a message from a connection-mode or connectionless-mode socket. It is normally used with connected sockets because and does not provide the source address of received data to the application.


int16 pro_recv (uint8 uint8Socket, void *pBuffer, uint32 uintLength, uint32 *pBytesReceived)


Arguments:


uint8Socket: file descriptor of socket.


pBuffer: pointer to the buffer where message should be stored.


uintLength: length in bytes of the message to be received.


pBytesReceived: pointer to an integer for returning number of bytes actually received.


Return Value:


Upon successful completion, SUCCESS is returned along with number of bytes in the reference passed as a parameter, else returns appropriate error code.


pro_close—deallocates the file descriptor and makes the file descriptor available for functions which allocate file descriptors. All outstanding record locks owned by the process on the file associated with the file descriptor are removed. Causes the socket to be destroyed. If the socket is in connection-oriented, and the SO_LINGER option is set for the socket with non-zero linger time, and the socket has un-transmitted data, then pro_close( ) blocks for up to the current linger interval for all pending data to be transmitted.


int16 pro_close (uint8 uint8Socket)


Arguments:


uint8Socket: file descriptor of socket that needs to be closed.


Return Value:


Upon successful completion, function shall return SUCCESS; otherwise appropriate error code shall be returned.


One skilled in the art will recognize that in addition to the exemplary API illustrated above for the Manager Layer, API's for the Session, Transport and Data Link Layers may be implemented as desired to communicate the messages shown in FIGS. 10A-D, 11A-B and 12A-B depending on the desired application.


One or more embodiments of the invention may be implemented as a system or method. For example at least one embodiment may include a medical device communication method that includes accepting a request by a programmable device to obtain a device identifier associated with a transmitting device associated with the request, a connection type of connection-oriented or connectionless-oriented, and a receiving device number associated with a receiving device to transmit a message to. The method may also include determining a port number of a port to transmit said message to, for example either via a requesting programmable device or the programmable device that receives the request. Embodiments may also include generating a communication identifier or CID for at least the advantages stated throughout this disclosure. Embodiments may also include accepting a request associated with a medical function, inserting the CID and the medical function into the message, determining if the connection type is connection-oriented or connectionless and transmitting the message to a medical device. This scenario is shown with exemplary values to demonstrate the previous message formatting and transfer in FIGS. 13A and 13B, which are intended to couple with one another on the right side of FIG. 13A and the left side of FIG. 13B.


Embodiments may also include transmitting the message to the receiving device even if the receiving device is not directly connected to the transmitting device. This enables built in routing that allows for devices to pass through messages without requiring a master to control all phases of communication for example.


Embodiments may also include accepting a multicast request configured to enable multiple receiving devices to receive the message. Embodiments may further include accepting a priority parameter configured to enable prioritized handling of the message. This enables messages with high priority to be delivered before other lower priority messages and in one or more embodiments may be implemented with a plurality of message data structures such as queues, linked lists or any other data structure or structures. Embodiments may include transmitting messages from a high priority message queue before transmitting data from a low priority message queue. Other embodiments may apply any type of strategy pattern to the delivery process, and may for example change strategies depending on the type of messages that are likely to be received in particular time periods. This enables predictive handling and processing of messages to provide intelligent and robust delivery of medical functions.


Embodiments may also include determining if a size of data to transfer is larger than a predetermined fragmentation value and packing the data in a plurality of messages to facilitate transfer. Embodiments may efficiently utilize memory and for example reduce latency by copying a pointer to the message between a plurality of message layers without copying the message itself. This is the case since the message does not have to be reconstructed in full within the stack until the full message is received in the application. Furthermore, embodiments of the invention may utilize optimized memory management that includes requesting memory from a buffer that includes non-uniform sizes to further increase efficiency of data memory utilization and lower overall required memory. When sending data packets or message that are larger than the maximum size allowed by the underlying hardware, embodiments may include setting a last fragmentation flag in a final message of fragmented message, starting a timer for an acknowledgement and retransmitting the final message if said timer expires. Further increases in efficiency may be achieved by embodiments that include receiving a request to change a window size for receipt of fragmented messages and adjusting memory usage based thereon, for example having lower window sizes for more reliable communication links. Embodiments may also include providing the device identifier to a new medical device that replaces the medical device after hot-swapping the new medical device for the original medical device, i.e., if a failure occurs. This allows embodiments of the invention to provide robust functionality and transparent replacement of hardware without interrupting medical functions or at least minimizing the interruptions. Embodiments may also include providing a pointer to a complete message after receipt of multiple fragmented messages without copying received message data after receipt thereof. This enables incoming data to be inserted into a buffer once and given to the application after the data is received without extraneous copying for example, which reduces memory utilization and programmable device processing required. One or more embodiments of the invention may include accepting an infusion request associated with an infusion related medical function. Any other type of medical function is in keeping with the spirit of the invention.


Embodiments of the system may include a programmable device configured to accept a request to obtain a device identifier associated with a transmitting device associated with the request, a connection type of connection-oriented or connectionless-oriented, a receiving device number associated with a receiving device to transmit a message to. Embodiments of the system may further determine a port number of a port to transmit said message to, generate a communication identifier or CID and accept a request associated with a medical function. The system may also insert the CID and the medical function into the message, determine if the connection type is connection-oriented or connectionless and transmit the message to a medical device. Embodiments of the system may also implement all functionality of the method previously described and may utilize any of the data structures or API's described herein in combination.


While the invention herein disclosed has been described by means of specific embodiments and applications thereof, numerous modifications and variations could be made thereto by those skilled in the art without departing from the scope of the invention set forth in the claims.

Claims
  • 1. A communication system for connecting a pump motor controller with a user interface controller, the communication system comprising: a pump motor controller configured to transmit a first message to a user interface controller, the first message comprising a request for an address;a user interface controller configured to: receive the first message;determine in a stored table that there is an entry corresponding to the pump motor controller;generate a connection identifier for the pump controller based on the lookup in the stored table;transmit the connection identifier to the pump controller;receive instructions for infusion, the instructions comprising infusion parameters;transmit the instructions in a second message including the connection identifier to the pump motor controller;receive a request from a second pump motor controller for an address, the second pump motor controller configured to replace the pump motor controller;determine in the stored table the entry corresponding to the pump motor controller that is being replaced; andrespond to the second pump motor controller's request with the same determined entry.
  • 2. The communication system of claim 1, wherein the user interface controller is further configured to receive a third message from the pump motor controller, the third message intended for an additional hardware, and transmit the third message to the additional hardware, wherein the pump motor controller and the additional hardware is not directly connected.
  • 3. The communication system of claim 1, wherein the second message is transferred between a plurality of message layers by copying a pointer and without copying said second message itself.
  • 4. The communication system of claim 1, wherein a session layer communication is made independent of bus topology.
  • 5. The communication system of claim 1, wherein a fragmented message is reassembled into a complete message in an application buffer.
  • 6. The communication system of claim 1, wherein the user interface controller is further configured to: determine that a size of data to transfer is larger than a predetermined fragmentation value; andpack said data in a plurality of messages independent of an underlying data bus width.
  • 7. The communication system of claim 1, wherein the user interface controller is further configured to request memory from a buffer comprising non-uniform sizes.
  • 8. The communication system of claim 1, wherein the pump motor controller is connected with the user interface controller without altering an application of the pump motor controller.
US Referenced Citations (1009)
Number Name Date Kind
4024864 Davies et al. May 1977 A
4055175 Clemens et al. Oct 1977 A
4151845 Clemens May 1979 A
4213454 Shim Jul 1980 A
4240438 Updike et al. Dec 1980 A
4280494 Cosgrove et al. Jul 1981 A
4308866 Jeliffe Jan 1982 A
4370983 Lichtenstein et al. Feb 1983 A
4373527 Fischell Feb 1983 A
4392849 Petre et al. Jul 1983 A
4395259 Prestele et al. Jul 1983 A
4457751 Rodler Jul 1984 A
4464170 Clemens Aug 1984 A
4469481 Kobayashi Sep 1984 A
4475901 Kraegen et al. Oct 1984 A
4494950 Fischell Jan 1985 A
4498843 Schneider et al. Feb 1985 A
4515584 Abe et al. May 1985 A
4526568 Clemens et al. Jul 1985 A
4529401 Leslie et al. Jul 1985 A
4543955 Schroeppel Oct 1985 A
4551133 Zegers de Beyl et al. Nov 1985 A
4553958 LeCocq Nov 1985 A
4559037 Franetzki et al. Dec 1985 A
4613937 Batty Sep 1986 A
4624661 Arimond Nov 1986 A
4633878 Bombardieri Jan 1987 A
4634426 kamen Jan 1987 A
4634427 Hannula et al. Jan 1987 A
4674652 Aten et al. Jun 1987 A
4676776 Howson et al. Jun 1987 A
4679562 Luksha Jul 1987 A
4685903 Cable et al. Aug 1987 A
4695954 Rose Sep 1987 A
4696671 Epstein et al. Sep 1987 A
4714462 DiDomenico Dec 1987 A
4722734 Kolin Feb 1988 A
4731051 Fischell Mar 1988 A
4741732 Crankshaw et al. May 1988 A
4756706 Kerns et al. Jul 1988 A
4776842 Franetzki et al. Oct 1988 A
4785969 McLaughlin Nov 1988 A
4803625 Fu et al. Feb 1989 A
4835372 Gombrich et al. May 1989 A
4838275 Lee Jun 1989 A
4838856 Mulreany et al. Jun 1989 A
4838857 Strowe et al. Jun 1989 A
4854324 Hirschman et al. Aug 1989 A
4857716 Gombrich et al. Aug 1989 A
4858154 Anderson et al. Aug 1989 A
4898578 Rubalcaba, Jr. Feb 1990 A
4908017 Howson et al. Mar 1990 A
4933873 Kaufman et al. Jun 1990 A
4943279 Samiotes et al. Jul 1990 A
4946439 Eggers Aug 1990 A
4953745 Rowlett Sep 1990 A
4978335 Arthur, III Dec 1990 A
5000739 Kulisz et al. Mar 1991 A
5010473 Jacobs Apr 1991 A
5014698 Cohen May 1991 A
5016172 Dessertine May 1991 A
5026084 Paisfield Jun 1991 A
5034004 Crankshaw Jul 1991 A
5041086 Koenig et al. Aug 1991 A
5058161 Weiss Oct 1991 A
5078683 Sancoff et al. Jan 1992 A
5084828 Kaufman et al. Jan 1992 A
5088981 Howson et al. Feb 1992 A
5097505 Weiss Mar 1992 A
5100380 Epstein et al. Mar 1992 A
5102392 Sakai et al. Apr 1992 A
5104374 Bishko et al. Apr 1992 A
5109850 Blanco et al. May 1992 A
5131816 Brown Jul 1992 A
5142484 Kaufman et al. Aug 1992 A
5153827 Coutre et al. Oct 1992 A
5157640 Backner Oct 1992 A
5161222 Montejo et al. Nov 1992 A
5177993 Beckman et al. Jan 1993 A
5181910 Scanlon Jan 1993 A
5190522 Wocicki et al. Mar 1993 A
5199439 Zimmerman et al. Apr 1993 A
5200891 Kehr et al. Apr 1993 A
5216597 Beckers Jun 1993 A
5221268 Barton et al. Jun 1993 A
5230061 Welch Jul 1993 A
5243982 Mostl et al. Sep 1993 A
5244463 Cordner, Jr. et al. Sep 1993 A
5249260 Nigawara et al. Sep 1993 A
5256156 Kern et al. Oct 1993 A
5256157 Samiotes et al. Oct 1993 A
5261702 Mayfield Nov 1993 A
5317506 Coutre et al. May 1994 A
5319355 Russek Jun 1994 A
5319363 Welch et al. Jun 1994 A
5330634 Wong et al. Jul 1994 A
5338157 Blomquist Aug 1994 A
5341476 Lowell Aug 1994 A
5364346 Schrezenmeir Nov 1994 A
5366346 Danby Nov 1994 A
5368562 Blomquist et al. Nov 1994 A
5373454 Kanda et al. Dec 1994 A
5376070 Purvis et al. Dec 1994 A
5378231 Johnson et al. Jan 1995 A
5389071 Kawahara et al. Feb 1995 A
5389078 Zalesky et al. Feb 1995 A
5417222 Dempsey et al. May 1995 A
5423748 Uhala Jun 1995 A
5429602 Hauser Jul 1995 A
5431627 Pastrone et al. Jul 1995 A
5432777 Le Boudec et al. Jul 1995 A
5445621 Poli et al. Aug 1995 A
5447164 Shaya et al. Sep 1995 A
5455851 Chaco et al. Oct 1995 A
5461365 Schlager et al. Oct 1995 A
5464392 Epstein et al. Nov 1995 A
5465082 Chaco Nov 1995 A
5485408 Blomquist Jan 1996 A
5486286 Peterson et al. Jan 1996 A
5493430 Lu et al. Feb 1996 A
5496273 Pastrone et al. Mar 1996 A
5505828 Wong et al. Apr 1996 A
5507288 Bocker et al. Apr 1996 A
5507786 Morgan et al. Apr 1996 A
5508499 Ferrario Apr 1996 A
5515713 Saugues et al. May 1996 A
5520637 Pager et al. May 1996 A
5522798 Johnson et al. Jun 1996 A
5547470 Johnson et al. Aug 1996 A
5554013 Owens et al. Sep 1996 A
5562615 Nassif Oct 1996 A
5577169 Prezioso Nov 1996 A
5582323 Kurtenbach Dec 1996 A
5582593 Hultman Dec 1996 A
5594786 Chaco et al. Jan 1997 A
5598519 Narayanan Jan 1997 A
5620608 Rosa et al. Apr 1997 A
5630710 Tune et al. May 1997 A
5636044 Yuan et al. Jun 1997 A
5643212 Coutre et al. Jul 1997 A
5651775 Walker et al. Jul 1997 A
5658131 Aoki et al. Aug 1997 A
5658250 Blomquist et al. Aug 1997 A
5665065 Colman et al. Sep 1997 A
5669877 Blomquist Sep 1997 A
5672154 Sillén et al. Sep 1997 A
5681285 Ford et al. Oct 1997 A
5685844 Marttila Nov 1997 A
5687717 Halpern et al. Nov 1997 A
5689229 Chaco et al. Nov 1997 A
5697899 Hillman et al. Dec 1997 A
5699509 Gary et al. Dec 1997 A
5713856 Eggers et al. Feb 1998 A
5718562 Lawless et al. Feb 1998 A
5719761 Gatti et al. Feb 1998 A
5733259 Valcke et al. Mar 1998 A
5738102 Lemelson Apr 1998 A
5744027 Connell et al. Apr 1998 A
5752621 Passamante May 1998 A
5754111 Garcia May 1998 A
5764034 Bowman et al. Jun 1998 A
5764159 Neftel et al. Jun 1998 A
5772635 Dastur et al. Jun 1998 A
5774865 Glynn Jun 1998 A
5778256 Darbee Jul 1998 A
5778345 McCartney Jul 1998 A
5781442 Engleson et al. Jul 1998 A
5782805 Meinzer et al. Jul 1998 A
5788669 Peterson Aug 1998 A
5797515 Liff et al. Aug 1998 A
5800387 Duffy et al. Sep 1998 A
5814015 Gargano et al. Sep 1998 A
5822544 Chaco et al. Oct 1998 A
5822715 Worthington et al. Oct 1998 A
5827179 Lichter et al. Oct 1998 A
5832448 Brown Nov 1998 A
5836910 Duffy et al. Nov 1998 A
5850344 Conkright Dec 1998 A
5867821 Ballantyne et al. Feb 1999 A
5870733 Bass et al. Feb 1999 A
5871465 Vasko Feb 1999 A
5873731 Predergast Feb 1999 A
5885245 Lynch et al. Mar 1999 A
5897493 Brown Apr 1999 A
5897498 Canfield, II et al. Apr 1999 A
5910252 Truitt et al. Jun 1999 A
5912818 McGrady et al. Jun 1999 A
5915240 Karpf Jun 1999 A
5920054 Uber, III Jul 1999 A
5920263 Huttenhoff et al. Jul 1999 A
5924074 Evans Jul 1999 A
5931764 Freeman et al. Aug 1999 A
5935099 Peterson et al. Aug 1999 A
5935106 Olsen Aug 1999 A
5941846 Duffy et al. Aug 1999 A
5956501 Brown Sep 1999 A
5957885 Bollish et al. Sep 1999 A
5960085 de la Huerga Sep 1999 A
5961448 Swenson et al. Oct 1999 A
5967559 Abramowitz Oct 1999 A
5971594 Sahai et al. Oct 1999 A
5975081 Hood et al. Nov 1999 A
5990838 Burns et al. Nov 1999 A
5997476 Brown Dec 1999 A
6000828 Leet Dec 1999 A
6003006 Colella et al. Dec 1999 A
6012034 Hamparian et al. Jan 2000 A
6017318 Gauthier et al. Jan 2000 A
6021392 Lester et al. Feb 2000 A
6024539 Blomquist Feb 2000 A
6032155 de la Huerga Feb 2000 A
6032676 Moore Mar 2000 A
6073106 Rozen et al. Jun 2000 A
6104295 Gaisser et al. Aug 2000 A
6112182 Akers et al. Aug 2000 A
RE36871 Epstein et al. Sep 2000 E
6115390 Chuah Sep 2000 A
6122536 Sun et al. Sep 2000 A
6126637 Kriesel et al. Oct 2000 A
6135949 Russo et al. Oct 2000 A
6150942 O'Brien Nov 2000 A
6151643 Cheng et al. Nov 2000 A
6157914 Seto et al. Dec 2000 A
6159147 Lichter et al. Dec 2000 A
6167567 Chiles et al. Dec 2000 A
6182667 Hanks et al. Feb 2001 B1
6189105 Lopes Feb 2001 B1
6195589 Ketcham Feb 2001 B1
6208974 Campbell et al. Mar 2001 B1
6222323 Yamashita et al. Apr 2001 B1
6223440 Rashman May 2001 B1
6226277 Chuah May 2001 B1
6227371 Song May 2001 B1
6234176 Domae et al. May 2001 B1
6241704 Peterson et al. Jun 2001 B1
6248067 Causey, III et al. Jun 2001 B1
6249705 Snell Jun 2001 B1
6257265 Brunner et al. Jul 2001 B1
6259355 Chaco et al. Jul 2001 B1
6269340 Ford et al. Jul 2001 B1
6270455 Brown Aug 2001 B1
6271813 Palalau Aug 2001 B1
6277072 Bardy Aug 2001 B1
6280380 Bardy Aug 2001 B1
6283761 Joao Sep 2001 B1
6285665 Chuah Sep 2001 B1
6292860 Cochcroft, Jr. Sep 2001 B1
6312378 Bardy Nov 2001 B1
6327254 Chuah Dec 2001 B1
6330008 Razdow et al. Dec 2001 B1
6339718 Zatezalo et al. Jan 2002 B1
6346886 de la Huerga Feb 2002 B1
6363282 Nichols et al. Mar 2002 B1
6371719 Hildebrandt Apr 2002 B1
6377548 Chuah Apr 2002 B1
6388951 Matsumoto et al. May 2002 B1
6406426 Reuss et al. Jun 2002 B1
6408330 de la Huerga Jun 2002 B1
6418334 Unger et al. Jul 2002 B1
6427088 Bowman et al. Jul 2002 B1
6428483 Carlebach Aug 2002 B1
6442432 Lee Aug 2002 B2
6469991 Chuah Oct 2002 B1
6475180 Peterson et al. Nov 2002 B2
6482158 Mault Nov 2002 B2
6485418 Yasushi et al. Nov 2002 B2
6494694 Lawless et al. Dec 2002 B2
6494831 Koritzinsky Dec 2002 B1
6497680 Holst et al. Dec 2002 B1
6514460 Fendrock Feb 2003 B1
6517482 Eiden et al. Feb 2003 B1
6519569 White et al. Feb 2003 B1
6520930 Critchlow et al. Feb 2003 B2
6540672 Simonsen et al. Apr 2003 B1
6542902 Dulong et al. Apr 2003 B2
6544212 Galley et al. Apr 2003 B2
6544228 Heitmeier Apr 2003 B1
6546350 Hartmann et al. Apr 2003 B1
6551276 Mann et al. Apr 2003 B1
6554798 Mann et al. Apr 2003 B1
6558320 Causey et al. May 2003 B1
6558351 Steil et al. May 2003 B1
6565509 Say et al. May 2003 B1
6567416 Chuah May 2003 B1
6571294 Simmon et al. May 2003 B2
6572542 Houben et al. Jun 2003 B1
6572545 Knobbe et al. Jun 2003 B2
6578002 Derzay et al. Jun 2003 B1
6581117 Klein et al. Jun 2003 B1
6587034 Heiman et al. Jul 2003 B1
6589229 Connelly et al. Jul 2003 B1
6599281 Struys et al. Jul 2003 B1
6602191 Quy Aug 2003 B2
6605072 Struys et al. Aug 2003 B2
6628809 Rowe et al. Sep 2003 B1
6631353 Davis et al. Oct 2003 B1
6640246 Gardy, Jr. et al. Oct 2003 B1
6641533 Causey, III et al. Nov 2003 B2
6647299 Bourget Nov 2003 B2
6652455 Kocher Nov 2003 B1
6653937 Nelson et al. Nov 2003 B2
6659947 Carter et al. Dec 2003 B1
6669630 Joliat et al. Dec 2003 B1
6671563 Engleson et al. Dec 2003 B1
6673033 Sciulli et al. Jan 2004 B1
6674403 Gray et al. Jan 2004 B2
6681003 Linder et al. Jan 2004 B2
6689091 Bui et al. Feb 2004 B2
6692241 Watanabe et al. Feb 2004 B2
6694191 Starkweather et al. Feb 2004 B2
6694334 DuLong et al. Feb 2004 B2
6721286 Williams et al. Apr 2004 B1
6721582 Trepagnier et al. Apr 2004 B2
6725200 Rost Apr 2004 B1
6731989 Engleson et al. May 2004 B2
6740072 Starkweather et al. May 2004 B2
6751651 Crockett Jun 2004 B2
6752787 Causey, III et al. Jun 2004 B1
6753830 Gelbman Jun 2004 B2
6758810 Lebel et al. Jul 2004 B2
6773396 Flach et al. Aug 2004 B2
6774786 Havekost et al. Aug 2004 B1
6775577 Cmkovich et al. Aug 2004 B2
6780156 Haueter et al. Aug 2004 B2
6790198 White et al. Sep 2004 B1
6796956 Hartlaub et al. Sep 2004 B2
6799149 Hartlaub Sep 2004 B2
6809653 Mann et al. Oct 2004 B1
6811534 Bowman, IV et al. Nov 2004 B2
6816605 Rowe et al. Nov 2004 B2
6839753 Biondi et al. Jan 2005 B2
6852104 Blomquist Feb 2005 B2
6859134 Heiman et al. Feb 2005 B1
6871211 Labounty et al. Mar 2005 B2
6873268 Lebel et al. Mar 2005 B2
6876303 Reeder et al. Apr 2005 B2
6885881 Leonhardt Apr 2005 B2
6891525 Ogoro May 2005 B2
6899695 Herrera May 2005 B2
6915170 Engleson et al. Jul 2005 B2
6923763 Kovatchev et al. Aug 2005 B1
6924781 Gelbman Aug 2005 B1
6928338 Buchser et al. Aug 2005 B1
6936029 Mann et al. Aug 2005 B2
6945954 Hochman et al. Sep 2005 B2
6948492 Wemeling et al. Sep 2005 B2
6958677 Carter Oct 2005 B1
6958691 Anderson et al. Oct 2005 B1
6958705 Lebel et al. Oct 2005 B2
6961448 Nichols et al. Nov 2005 B2
6969352 Chiang et al. Nov 2005 B2
6969865 Duchon et al. Nov 2005 B2
6974437 Lebel et al. Dec 2005 B2
6979326 Mann et al. Dec 2005 B2
6985870 Martucci et al. Jan 2006 B2
6986347 Hickle Jan 2006 B2
6997880 Carlebach et al. Feb 2006 B2
6997920 Mann et al. Feb 2006 B2
6998984 Zittrain Feb 2006 B1
7017293 Riley Mar 2006 B2
7025743 Mann et al. Apr 2006 B2
7029455 Flaherty Apr 2006 B2
7038584 Carter May 2006 B2
7060031 Webb et al. Jun 2006 B2
7060059 Keith et al. Jun 2006 B2
7069552 Lindberg et al. Jun 2006 B2
7072725 Bristol et al. Jul 2006 B2
7079035 Bock et al. Jul 2006 B2
7092943 Roese et al. Aug 2006 B2
7096072 Engleson et al. Aug 2006 B2
7099809 Dori Aug 2006 B2
7103419 Engleson et al. Sep 2006 B2
7103578 Beck et al. Sep 2006 B2
7107106 Engleson et al. Sep 2006 B2
7108680 Rohr et al. Sep 2006 B2
7109878 Mann et al. Sep 2006 B2
7117041 Engleson et al. Oct 2006 B2
7136645 Hanson et al. Nov 2006 B2
7137964 Flaherty Nov 2006 B2
7142190 Martinez Nov 2006 B2
7150741 Erickson et al. Dec 2006 B2
7153289 Vasko Dec 2006 B2
7154397 Zerhusen et al. Dec 2006 B2
7156807 Carter et al. Jan 2007 B2
7161484 Tsoukalis et al. Jan 2007 B2
7167755 Seeberger et al. Jan 2007 B2
7167920 Traversat Jan 2007 B2
7171277 Engleson et al. Jan 2007 B2
7171492 Borella et al. Jan 2007 B1
7181493 English et al. Feb 2007 B2
7185288 McKeever Feb 2007 B2
7193514 Ritson Mar 2007 B2
7197025 Chuah Mar 2007 B2
7201734 Hickle Apr 2007 B2
7204823 Estes et al. Apr 2007 B2
7213009 Pestotnik May 2007 B2
7216802 de la Huerga May 2007 B1
7220240 Struys et al. May 2007 B2
7224979 Singhal et al. May 2007 B2
7229430 Hickle et al. Jun 2007 B2
7230529 Ketcherside Jun 2007 B2
7236936 White et al. Jun 2007 B2
7238164 Childers et al. Jul 2007 B2
7247154 Hickle Jul 2007 B2
7248239 Dowling Jul 2007 B2
7250856 Havekost et al. Jul 2007 B2
7255683 Vanderveen et al. Aug 2007 B2
7256888 Staehr et al. Aug 2007 B2
7258534 Fathallah et al. Aug 2007 B2
7263213 Rowe Aug 2007 B2
7267664 Rizzo Sep 2007 B2
7267665 Steil et al. Sep 2007 B2
7275156 Balfanz et al. Sep 2007 B2
7278983 Ireland et al. Oct 2007 B2
7289815 Gfeller et al. Oct 2007 B2
7289948 Mohri Oct 2007 B1
7293107 Hanson et al. Nov 2007 B1
7295119 Rappaport et al. Nov 2007 B2
7295556 Roese et al. Nov 2007 B2
7301451 Hastings Nov 2007 B2
7308300 Toews et al. Dec 2007 B2
7315825 Rosenfeld et al. Jan 2008 B2
7319386 Collins, Jr. et al. Jan 2008 B2
7324000 Zittrain et al. Jan 2008 B2
7327705 Fletcher et al. Feb 2008 B2
7343224 DiGianfilippo et al. Mar 2008 B2
7346025 Bryson Mar 2008 B2
7347836 Peterson et al. Mar 2008 B2
7354420 Steil et al. Apr 2008 B2
7369897 Boveja et al. May 2008 B2
7369948 Ferenczi et al. May 2008 B1
7383088 Spinelli et al. Jun 2008 B2
7384410 Eggers et al. Jun 2008 B2
7398183 Holland et al. Jul 2008 B2
7399277 Saidara et al. Jul 2008 B2
7402153 Steil et al. Jul 2008 B2
7420472 Tran Sep 2008 B2
7432807 Schmitt Oct 2008 B2
7447643 Olson Nov 2008 B1
7454314 Holland et al. Nov 2008 B2
7457804 Uber, III et al. Nov 2008 B2
7464040 Joao Dec 2008 B2
7471994 Ford et al. Dec 2008 B2
7483756 Engleson et al. Jan 2009 B2
7489808 Gerder Feb 2009 B2
7490021 Holland et al. Feb 2009 B2
7490048 Joao Feb 2009 B2
7491187 Van Den Berghe et al. Feb 2009 B2
7523401 Aldridge Apr 2009 B1
7524304 Genosar Apr 2009 B2
7551078 Carlson Jun 2009 B2
7559321 Wermeling et al. Jul 2009 B2
7565197 Haulbrich et al. Jul 2009 B2
7572230 Neumann et al. Aug 2009 B2
7578802 Hickle Aug 2009 B2
7621009 Elhabashy Nov 2009 B2
D606533 De Jong et al. Dec 2009 S
7636718 Steen et al. Dec 2009 B1
7640172 Kuth Dec 2009 B2
7645258 White et al. Jan 2010 B2
7647237 Malave et al. Jan 2010 B2
7662124 Duchon et al. Feb 2010 B2
7668731 Martucci et al. Feb 2010 B2
7671733 McNeal Mar 2010 B2
7678071 Lebel et al. Mar 2010 B2
7687678 Jacobs Mar 2010 B2
7697994 VanDanacker et al. Apr 2010 B2
7698239 Lieuallen Apr 2010 B2
7705727 Pestotnik Apr 2010 B2
7724147 Brown et al. May 2010 B2
7739126 Cave Jun 2010 B1
7746218 Collins, Jr. Jun 2010 B2
7766873 Moberg et al. Aug 2010 B2
7776029 Whitehurst et al. Aug 2010 B2
7776031 Hartlaub et al. Aug 2010 B2
7785313 Mastrototaro Aug 2010 B2
7806852 Jurson Oct 2010 B1
7806886 Kanderian, Jr. et al. Oct 2010 B2
7826981 Goode, Jr. et al. Nov 2010 B2
7835927 Schlotterbeck et al. Nov 2010 B2
7836314 Chieu Nov 2010 B2
7856276 Ripart et al. Dec 2010 B2
7860583 Condurso et al. Dec 2010 B2
7868754 Salvat, Jr. Jan 2011 B2
7871394 Halbert et al. Jan 2011 B2
7886231 Hopermann et al. Feb 2011 B2
7895053 Holland et al. Feb 2011 B2
7896842 Palmroos et al. Mar 2011 B2
7899546 Sieracki et al. Mar 2011 B2
7905710 Wang et al. Mar 2011 B2
7920061 Klein et al. Apr 2011 B2
7933780 de la Huerga Apr 2011 B2
7938796 Moubayed May 2011 B2
7945452 Fathallah et al. May 2011 B2
7974714 Hoffberg Jul 2011 B2
7996241 Zak Aug 2011 B2
8034026 Grant Oct 2011 B2
8038593 Friedman et al. Oct 2011 B2
8048040 Kiani Nov 2011 B2
8060576 Chan et al. Nov 2011 B2
8065161 Howard et al. Nov 2011 B2
8066672 Mandro Nov 2011 B2
8078983 Davis et al. Dec 2011 B2
8082018 Duchon et al. Dec 2011 B2
8082312 Chan et al. Dec 2011 B2
8147448 Sundar et al. Apr 2012 B2
8149131 Blornquist Apr 2012 B2
8169914 Bajpai May 2012 B2
8171094 Chan et al. May 2012 B2
8172798 Hungerford et al. May 2012 B2
8185322 Schroeder et al. May 2012 B2
8195478 Petersen et al. Jun 2012 B2
8206350 Mann et al. Jun 2012 B2
8219413 Martinez et al. Jul 2012 B2
8231578 Fathallah et al. Jul 2012 B2
8234128 Martucci et al. Jul 2012 B2
8267892 Spencer et al. Sep 2012 B2
8271106 Wehba et al. Sep 2012 B2
8287495 Michaud et al. Oct 2012 B2
8291337 Gannin et al. Oct 2012 B2
8298184 DiPerna et al. Oct 2012 B2
8352290 Bartz et al. Jan 2013 B2
8359338 Butterfield et al. Jan 2013 B2
8380536 Howard et al. Feb 2013 B2
8387112 Ranjan et al. Feb 2013 B1
8394077 Jacobson et al. Mar 2013 B2
8403908 Jacobson et al. Mar 2013 B2
8435206 Evans et al. May 2013 B2
8449523 Brukalo et al. May 2013 B2
8452953 Buck et al. May 2013 B2
8453645 Figueiredo et al. Jun 2013 B2
8480648 Burnett et al. Jul 2013 B2
8494879 Davis et al. Jul 2013 B2
8504179 Blomquist Aug 2013 B2
8517990 Teel et al. Aug 2013 B2
8518021 Stewart et al. Aug 2013 B2
8543416 Palmroos et al. Sep 2013 B2
8551038 Tsoukalis et al. Oct 2013 B2
8560345 Wehba et al. Oct 2013 B2
8577692 Silkaitis et al. Nov 2013 B2
8579884 Lanier et al. Nov 2013 B2
8655676 Wehba et al. Feb 2014 B2
8660860 Wehba et al. Feb 2014 B2
8662388 Belkin Mar 2014 B2
8666769 Butler et al. Mar 2014 B2
8700421 Feng et al. Apr 2014 B2
8731960 Butler et al. May 2014 B2
8768719 Wehba et al. Jul 2014 B2
8771251 Ruchti et al. Jul 2014 B2
8777894 Butterfield et al. Jul 2014 B2
8777895 Hsu et al. Jul 2014 B2
8799012 Butler et al. Aug 2014 B2
8876793 Ledford et al. Nov 2014 B2
8922330 Moberg et al. Dec 2014 B2
8936565 Chawla Jan 2015 B2
8952794 Bloomquist et al. Feb 2015 B2
8998100 Halbert et al. Apr 2015 B2
9026370 Rubalcaba et al. May 2015 B2
9069887 Gupta et al. Jun 2015 B2
9089642 Murphy et al. Jul 2015 B2
9114217 Sur et al. Aug 2015 B2
9123077 Silkaitis et al. Sep 2015 B2
9192712 DeBelser et al. Nov 2015 B2
9240002 Hume et al. Jan 2016 B2
9381296 Arrizza et al. Jul 2016 B2
9393362 Cozmi et al. Jul 2016 B2
9498583 Sur et al. Nov 2016 B2
9539383 Kohlbrecher Jan 2017 B2
9572923 Howard et al. Feb 2017 B2
9594875 Arrizza et al. Mar 2017 B2
9604000 Wehba et al. Mar 2017 B2
9641432 Jha et al. May 2017 B2
9649431 Gray et al. May 2017 B2
9662436 Belkin et al. May 2017 B2
9690909 Stewart et al. Jun 2017 B2
9707341 Dumas, III et al. Jul 2017 B2
9724470 Day et al. Aug 2017 B2
9764082 Day et al. Sep 2017 B2
20010016056 Westphal et al. Aug 2001 A1
20010031944 Peterson et al. Oct 2001 A1
20010032099 Joao Oct 2001 A1
20010037060 Thompson et al. Nov 2001 A1
20010044731 Coffman et al. Nov 2001 A1
20010051787 Haller et al. Dec 2001 A1
20010056358 Dulong et al. Dec 2001 A1
20020010595 Kapp Jan 2002 A1
20020013723 Mise Jan 2002 A1
20020015018 Shimazu et al. Feb 2002 A1
20020019584 Schulze et al. Feb 2002 A1
20020026103 Norris et al. Feb 2002 A1
20020029776 Blomquist Mar 2002 A1
20020032583 Joao Mar 2002 A1
20020040208 Flaherty et al. Apr 2002 A1
20020040282 Bailey et al. Apr 2002 A1
20020082728 Mueller et al. Jun 2002 A1
20020087115 Hartlaub Jul 2002 A1
20020087116 Hartlaub Jul 2002 A1
20020095486 Bahl Jul 2002 A1
20020103675 Vanelli Aug 2002 A1
20020123905 Goodroe et al. Sep 2002 A1
20020152239 Bautista-Lloyd et al. Oct 2002 A1
20020194329 Ailing Dec 2002 A1
20030009244 Engleson Jan 2003 A1
20030013959 Grunwald et al. Jan 2003 A1
20030014222 Klass et al. Jan 2003 A1
20030014817 Gallant et al. Jan 2003 A1
20030025602 Medema et al. Feb 2003 A1
20030028082 Thompson Feb 2003 A1
20030036683 Kehr et al. Feb 2003 A1
20030047126 Tomaschko Mar 2003 A1
20030050621 Lebel et al. Mar 2003 A1
20030059750 Bindler et al. Mar 2003 A1
20030060688 Ciarniello et al. Mar 2003 A1
20030069963 Jayant et al. Apr 2003 A1
20030079746 Hickle May 2003 A1
20030097529 Arimilli et al. May 2003 A1
20030104982 Wittmann et al. Jun 2003 A1
20030106553 Vanderveen Jun 2003 A1
20030115358 Yun Jun 2003 A1
20030120384 Haitin et al. Jun 2003 A1
20030125662 Bui Jul 2003 A1
20030130616 Steil Jul 2003 A1
20030135087 Hickle et al. Jul 2003 A1
20030139701 White et al. Jul 2003 A1
20030140928 Bui et al. Jul 2003 A1
20030140929 Wilkes et al. Jul 2003 A1
20030141981 Bui et al. Jul 2003 A1
20030143746 Sage, Jr. Jul 2003 A1
20030144878 Wilkes et al. Jul 2003 A1
20030158749 Olchanski et al. Aug 2003 A1
20030187338 Say et al. Oct 2003 A1
20030200116 Forrester Oct 2003 A1
20030204416 Acharya Oct 2003 A1
20030204781 Peebles et al. Oct 2003 A1
20030212364 Mann et al. Nov 2003 A1
20030212379 Bylund et al. Nov 2003 A1
20030217962 Childers et al. Nov 2003 A1
20040015132 Brown Jan 2004 A1
20040019607 Moubayed et al. Jan 2004 A1
20040030323 Ullestad et al. Feb 2004 A1
20040039257 Hickle Feb 2004 A1
20040057226 Berthou et al. Mar 2004 A1
20040064341 Langan et al. Apr 2004 A1
20040064342 Browne et al. Apr 2004 A1
20040064435 Moubayed et al. Apr 2004 A1
20040073811 Sanin Apr 2004 A1
20040077934 Massad Apr 2004 A1
20040078231 Wilkes et al. Apr 2004 A1
20040078236 Stoodley et al. Apr 2004 A1
20040122530 Hansen Jun 2004 A1
20040128162 Schlotterbeck et al. Jul 2004 A1
20040128163 Goodman et al. Jul 2004 A1
20040133441 Brady et al. Jul 2004 A1
20040145480 Despotis Jul 2004 A1
20040147034 Gore et al. Jul 2004 A1
20040167464 Ireland et al. Aug 2004 A1
20040167465 Kohler Aug 2004 A1
20040167804 Simpson Aug 2004 A1
20040172222 Simpson et al. Sep 2004 A1
20040172283 Vanderveen Sep 2004 A1
20040172301 Mihai et al. Sep 2004 A1
20040172302 Martucci et al. Sep 2004 A1
20040176667 Mihai et al. Sep 2004 A1
20040176980 Bulitta et al. Sep 2004 A1
20040176984 White et al. Sep 2004 A1
20040181314 Zaleski Sep 2004 A1
20040189708 Larcheveque et al. Sep 2004 A1
20040193325 Bonderud Sep 2004 A1
20040193328 Butterfield et al. Sep 2004 A1
20040193453 Butterfield et al. Sep 2004 A1
20040204673 Flaherty et al. Oct 2004 A1
20040215278 Stegink et al. Oct 2004 A1
20040220517 Starkweather et al. Nov 2004 A1
20040225252 Gillespie et al. Nov 2004 A1
20040236240 Kraus et al. Nov 2004 A1
20040243438 Mintz Dec 2004 A1
20040254434 Goodnow et al. Dec 2004 A1
20050010269 Lebel et al. Jan 2005 A1
20050020886 Hutchinson et al. Jan 2005 A1
20050021006 Tonnies Jan 2005 A1
20050027560 Cook Feb 2005 A1
20050027567 Taha Feb 2005 A1
20050038311 Kuth Feb 2005 A1
20050038669 Sachdeva et al. Feb 2005 A1
20050038680 McMahon Feb 2005 A1
20050040226 Al-Sheikh Feb 2005 A1
20050043620 Fallows et al. Feb 2005 A1
20050049910 Lancaster et al. Mar 2005 A1
20050055242 Bello et al. Mar 2005 A1
20050055244 Mullan et al. Mar 2005 A1
20050065465 Lebel et al. Mar 2005 A1
20050065817 Mihai et al. Mar 2005 A1
20050075544 Shapiro et al. Apr 2005 A1
20050080801 Kothandaraman et al. Apr 2005 A1
20050086071 Fox, Jr. et al. Apr 2005 A1
20050086072 Fox Apr 2005 A1
20050090808 Malave et al. Apr 2005 A1
20050099624 Staehr May 2005 A1
20050102162 Blumenfeld May 2005 A1
20050102669 Marney et al. May 2005 A1
20050107923 Vanderveen May 2005 A1
20050117529 Ramos-Escano Jun 2005 A1
20050119788 Engleson et al. Jun 2005 A1
20050119914 Batch Jun 2005 A1
20050131739 Rabinowitz et al. Jun 2005 A1
20050137522 Aoki Jun 2005 A1
20050137573 McLaughlin Jun 2005 A1
20050154769 Eckart et al. Jul 2005 A1
20050160057 Wefers et al. Jul 2005 A1
20050171503 Van Den Berghe et al. Aug 2005 A1
20050171815 Vanderveen Aug 2005 A1
20050177096 Bollish et al. Aug 2005 A1
20050177395 Blomquist Aug 2005 A1
20050182306 Sloan Aug 2005 A1
20050182355 Bui Aug 2005 A1
20050187950 Parker Aug 2005 A1
20050192557 Brauker et al. Sep 2005 A1
20050197554 Polcha Sep 2005 A1
20050197621 Poulsen et al. Sep 2005 A1
20050210037 Wefers et al. Sep 2005 A1
20050216479 Wefers et al. Sep 2005 A1
20050216480 Wefers et al. Sep 2005 A1
20050223045 Funahashi et al. Oct 2005 A1
20050224083 Crass Oct 2005 A1
20050234746 Funahashi Oct 2005 A1
20050240305 Bogash et al. Oct 2005 A1
20050246416 Blomquist Nov 2005 A1
20050251418 Fox, Jr. et al. Nov 2005 A1
20050273059 Mernoe et al. Dec 2005 A1
20050277873 Stewart et al. Dec 2005 A1
20050277890 Stewart et al. Dec 2005 A1
20050277911 Stewart et al. Dec 2005 A1
20050278194 Holland et al. Dec 2005 A1
20060004772 Hagan et al. Jan 2006 A1
20060009727 O'Mahony et al. Jan 2006 A1
20060009734 Martin Jan 2006 A1
20060010098 Goodnow et al. Jan 2006 A1
20060042139 Mendes Mar 2006 A1
20060047270 Shelton Mar 2006 A1
20060053036 Coffman et al. Mar 2006 A1
20060064020 Burnes et al. Mar 2006 A1
20060074633 Mahesh et al. Apr 2006 A1
20060074920 Wefers et al. Apr 2006 A1
20060079831 Gilbert Apr 2006 A1
20060089854 Holland et al. Apr 2006 A1
20060089855 Holland et al. Apr 2006 A1
20060100746 Leibner-Druska May 2006 A1
20060100907 Holland et al. May 2006 A1
20060106649 Eggers et al. May 2006 A1
20060111943 Wu May 2006 A1
20060116904 Brem Jun 2006 A1
20060116907 Rhodes et al. Jun 2006 A1
20060122481 Sievenpiper et al. Jun 2006 A1
20060122867 Eggers et al. Jun 2006 A1
20060129429 Moubayed et al. Jun 2006 A1
20060129434 Smitherman et al. Jun 2006 A1
20060129435 Smitherman et al. Jun 2006 A1
20060136266 Tarassenko et al. Jun 2006 A1
20060136271 Eggers et al. Jun 2006 A1
20060143051 Eggers et al. Jun 2006 A1
20060173260 Gaoni et al. Aug 2006 A1
20060173406 Hayes et al. Aug 2006 A1
20060173715 Wang et al. Aug 2006 A1
20060190302 Eggers et al. Aug 2006 A1
20060195022 Trepagnier et al. Aug 2006 A1
20060200007 Brockway et al. Sep 2006 A1
20060200369 Batch et al. Sep 2006 A1
20060211404 Cromp et al. Sep 2006 A1
20060224141 Rush et al. Oct 2006 A1
20060229918 Fotsch et al. Oct 2006 A1
20060258985 Russell Nov 2006 A1
20060259327 Hoag Nov 2006 A1
20060264895 Flanders Nov 2006 A1
20060265246 Hoag Nov 2006 A1
20060267753 Hussey et al. Nov 2006 A1
20060268710 Appanna et al. Nov 2006 A1
20060277206 Bailey et al. Dec 2006 A1
20060287885 Frick Dec 2006 A1
20070015972 Wang et al. Jan 2007 A1
20070016443 Wachman et al. Jan 2007 A1
20070027506 Stender et al. Feb 2007 A1
20070060796 Kim Mar 2007 A1
20070060870 Tolle et al. Mar 2007 A1
20070060871 Istoc Mar 2007 A1
20070065363 Dalal et al. Mar 2007 A1
20070073419 Sesay Mar 2007 A1
20070078314 Grounsell Apr 2007 A1
20070083870 Kanakogi Apr 2007 A1
20070088333 Levin et al. Apr 2007 A1
20070093786 Goldsmith et al. Apr 2007 A1
20070100665 Brown May 2007 A1
20070100667 Bardy May 2007 A1
20070106126 Mannheimer et al. May 2007 A1
20070112298 Mueller et al. May 2007 A1
20070116037 Moore May 2007 A1
20070118405 Campbell et al. May 2007 A1
20070135866 Baker Jun 2007 A1
20070136098 Smythe et al. Jun 2007 A1
20070142822 Remde Jun 2007 A1
20070156282 Dunn Jul 2007 A1
20070156452 Batch Jul 2007 A1
20070169008 Varanasi et al. Jul 2007 A1
20070179448 Lim et al. Aug 2007 A1
20070186923 Poutiatine et al. Aug 2007 A1
20070191817 Martin Aug 2007 A1
20070191973 Holzbauer et al. Aug 2007 A1
20070213657 Jennewine et al. Sep 2007 A1
20070214003 Holland et al. Sep 2007 A1
20070215545 Bissler et al. Sep 2007 A1
20070229249 McNeal et al. Oct 2007 A1
20070232867 Hansmann Oct 2007 A1
20070233035 Wehba et al. Oct 2007 A1
20070233049 Wehba et al. Oct 2007 A1
20070233206 Frikart Oct 2007 A1
20070233520 Wehba et al. Oct 2007 A1
20070251835 Mehta et al. Nov 2007 A1
20070253021 Mehta et al. Nov 2007 A1
20070254593 Jollota et al. Nov 2007 A1
20070255125 Moberg et al. Nov 2007 A1
20070257788 Carlson Nov 2007 A1
20070258395 Jollota et al. Nov 2007 A1
20070299687 Palmer et al. Dec 2007 A1
20070299695 Jung et al. Dec 2007 A1
20080004904 Tran Jan 2008 A1
20080009684 Corsetti et al. Jan 2008 A1
20080033361 Evans et al. Feb 2008 A1
20080034323 Blomquist Feb 2008 A1
20080041942 Aissa Feb 2008 A1
20080052704 Wysocki Feb 2008 A1
20080065007 Peterson et al. Mar 2008 A1
20080065417 Jung et al. Mar 2008 A1
20080071217 Moubayed et al. Mar 2008 A1
20080071251 Moubayed et al. Mar 2008 A1
20080091466 Butler et al. Apr 2008 A1
20080095339 Elliott Apr 2008 A1
20080097289 Steil et al. Apr 2008 A1
20080126969 Blomquist May 2008 A1
20080139907 Rao et al. Jun 2008 A1
20080149117 Raghuram Jun 2008 A1
20080154177 Moubayed et al. Jun 2008 A1
20080172337 Banfield et al. Jul 2008 A1
20080184219 Matsumoto Jul 2008 A1
20080188796 Steil et al. Aug 2008 A1
20080214919 Harmon et al. Sep 2008 A1
20080246748 Cassidy et al. Oct 2008 A1
20080256305 Kwon Oct 2008 A1
20080262469 Bristol et al. Oct 2008 A1
20080269714 Mastrototaro et al. Oct 2008 A1
20080269723 Mastrototaro et al. Oct 2008 A1
20080275384 Mastrototaro et al. Nov 2008 A1
20080300572 Rankers et al. Dec 2008 A1
20080320387 Sasaki et al. Dec 2008 A1
20080320466 Dias Dec 2008 A1
20090005703 Fasciano Jan 2009 A1
20090005728 Weinert et al. Jan 2009 A1
20090006061 Thukral et al. Jan 2009 A1
20090006129 Thukral Jan 2009 A1
20090006133 Weinert Jan 2009 A1
20090018495 Panduro Jan 2009 A1
20090051560 Manning et al. Feb 2009 A1
20090054743 Stewart Feb 2009 A1
20090054754 McMahon et al. Feb 2009 A1
20090057399 Sajkowsky Mar 2009 A1
20090069785 Miller et al. Mar 2009 A1
20090099867 Newman Apr 2009 A1
20090135196 Holland et al. May 2009 A1
20090143662 Estes et al. Jun 2009 A1
20090149743 Barron et al. Jun 2009 A1
20090150174 Buck et al. Jun 2009 A1
20090156991 Roberts Jun 2009 A1
20090157695 Roberts Jun 2009 A1
20090158274 Roberts Jun 2009 A1
20090177146 Nesbitt et al. Jul 2009 A1
20090177769 Roberts Jul 2009 A1
20090177992 Rubalcaba et al. Jul 2009 A1
20090183147 Davis et al. Jul 2009 A1
20090209938 Aalto-Setala Aug 2009 A1
20090210250 Prax et al. Aug 2009 A1
20090221890 Saffer et al. Sep 2009 A1
20090231249 Wang et al. Sep 2009 A1
20090270833 DeBelser Oct 2009 A1
20090275886 Bloomquist et al. Nov 2009 A1
20090275896 Kamen et al. Nov 2009 A1
20090284691 Marhefka et al. Nov 2009 A1
20090326340 Wang Dec 2009 A1
20090326516 Bangera et al. Dec 2009 A1
20100022988 Wochner Jan 2010 A1
20100036310 Hillman Feb 2010 A1
20100056992 Hayter Mar 2010 A1
20100095229 Dixon et al. Apr 2010 A1
20100121170 Rule May 2010 A1
20100121415 Skelton et al. May 2010 A1
20100121654 Portnoy et al. May 2010 A1
20100130933 Holland et al. May 2010 A1
20100131434 Magent et al. May 2010 A1
20100138523 Umess et al. Jun 2010 A1
20100146137 Wu et al. Jun 2010 A1
20100156633 Buck et al. Jun 2010 A1
20100160854 Gauthier Jun 2010 A1
20100160860 Celentano et al. Jun 2010 A1
20100191525 Rabenko et al. Jul 2010 A1
20100198034 Thomas et al. Aug 2010 A1
20100198196 Wei Aug 2010 A1
20100200506 Ware et al. Aug 2010 A1
20100212675 Walling et al. Aug 2010 A1
20100217621 Schoenberg Aug 2010 A1
20100234708 Buck et al. Sep 2010 A1
20100250732 Bucknell Sep 2010 A1
20100271479 Heydlauf Oct 2010 A1
20100273738 Valcke et al. Oct 2010 A1
20100280486 Khair et al. Nov 2010 A1
20100292634 Kircher Nov 2010 A1
20100298765 Budiman et al. Nov 2010 A1
20100318025 John Dec 2010 A1
20110001605 Kiani et al. Jan 2011 A1
20110040158 Katz et al. Feb 2011 A1
20110060758 Schlotterbeck et al. Mar 2011 A1
20110071844 Cannon et al. Mar 2011 A1
20110072379 Gannon Mar 2011 A1
20110078608 Gannon et al. Mar 2011 A1
20110093284 Dicks et al. Apr 2011 A1
20110099313 Bolanowski Apr 2011 A1
20110125095 Lebel et al. May 2011 A1
20110175728 Baker, Jr. Jul 2011 A1
20110178462 Moberg et al. Jul 2011 A1
20110257496 Terashima et al. Oct 2011 A1
20110257798 Ali et al. Oct 2011 A1
20110259954 Bartz et al. Oct 2011 A1
20110264043 Kotnick et al. Oct 2011 A1
20110264044 Bartz et al. Oct 2011 A1
20110266221 Ware et al. Nov 2011 A1
20110270045 Lebel et al. Nov 2011 A1
20110275904 Lebel et al. Nov 2011 A1
20110286457 Ee Nov 2011 A1
20110289497 Kiaie et al. Nov 2011 A1
20110295196 Chazot et al. Dec 2011 A1
20110295341 Estes et al. Dec 2011 A1
20110296051 Vange Dec 2011 A1
20110296411 Tang et al. Dec 2011 A1
20110313789 Karmen et al. Dec 2011 A1
20110319813 Kamen et al. Dec 2011 A1
20110320049 Chossat et al. Dec 2011 A1
20120011253 Friedman et al. Jan 2012 A1
20120016305 Jollota Jan 2012 A1
20120029941 Malave et al. Feb 2012 A1
20120070045 Vesper et al. Mar 2012 A1
20120095437 Hemmerling Apr 2012 A1
20120112903 Kaib et al. May 2012 A1
20120130198 Beaule May 2012 A1
20120143116 Ware et al. Jun 2012 A1
20120150556 Galasso et al. Jun 2012 A1
20120179135 Rinehart et al. Jul 2012 A1
20120179136 Rinehart et al. Jul 2012 A1
20120203177 Lanier Aug 2012 A1
20120245554 Kawamura Sep 2012 A1
20120259978 Petersen et al. Oct 2012 A1
20120277716 Ali et al. Nov 2012 A1
20120284734 McQuaid et al. Nov 2012 A1
20120323212 Murphy Dec 2012 A1
20130006666 Schneider Jan 2013 A1
20130006702 Wu Jan 2013 A1
20130012880 Blomquist Jan 2013 A1
20130015980 Evans et al. Jan 2013 A1
20130036403 Geist Feb 2013 A1
20130036412 Birtwhistle et al. Feb 2013 A1
20130066265 Grant Mar 2013 A1
20130072872 Yodfat et al. Mar 2013 A1
20130096444 Condurso et al. Apr 2013 A1
20130096648 Benson Apr 2013 A1
20130102963 Marsh et al. Apr 2013 A1
20130138452 Cork et al. May 2013 A1
20130144206 Lee et al. Jun 2013 A1
20130158504 Ruchti et al. Jun 2013 A1
20130167245 Birtwhistle et al. Jun 2013 A1
20130191770 Bartz et al. Jul 2013 A1
20130218080 Peterfreund et al. Aug 2013 A1
20130261993 Ruchti et al. Oct 2013 A1
20130274669 Stempfle et al. Oct 2013 A1
20130275539 Gross et al. Oct 2013 A1
20130291116 Homer Oct 2013 A1
20130296823 Melker et al. Nov 2013 A1
20130296984 Burnett et al. Nov 2013 A1
20140039446 Day Feb 2014 A1
20140257251 Bush et al. Sep 2014 A1
20140269643 Sun Sep 2014 A1
20140350513 Oruklu et al. Nov 2014 A1
20140358077 Oruklu et al. Dec 2014 A1
20140366878 Baron Dec 2014 A1
20150005935 Bae et al. Jan 2015 A1
20150058044 Butler et al. Feb 2015 A1
20150066531 Jacobson et al. Mar 2015 A1
20150100038 McCann et al. Apr 2015 A1
20150134265 Kohlbrecher et al. May 2015 A1
20150141955 Ruchti et al. May 2015 A1
20150151051 Tsoukalis Jun 2015 A1
20150379237 Mills et al. Dec 2015 A1
20160051749 Istoc Feb 2016 A1
20160051751 Silkaitis et al. Feb 2016 A1
20160103960 Hume et al. Apr 2016 A1
20160228633 Welsch et al. Aug 2016 A1
20160350513 Jacobson et al. Dec 2016 A1
20170024534 Arrizza et al. Jan 2017 A1
20170246388 Kohlbrecher Aug 2017 A1
20170274140 Howard et al. Sep 2017 A1
20170286637 Arrizza et al. Oct 2017 A1
20170319780 Belkin et al. Nov 2017 A1
20180008772 Wehba et al. Jan 2018 A1
20180028742 Day et al. Feb 2018 A1
20180043094 Day et al. Feb 2018 A1
Foreign Referenced Citations (115)
Number Date Country
2 060 151 Aug 1997 CA
2 125 300 Oct 1999 CA
31 12 762 Jan 1983 DE
34 35 647 Jul 1985 DE
198 44 252 Mar 2000 DE
199 32 147 Jan 2001 DE
103 52 456 Jul 2005 DE
0 319 267 Jun 1989 EP
0 380 061 Aug 1990 EP
0 384 155 Aug 1990 EP
0 460 533 Dec 1991 EP
0 564 127 Jun 1993 EP
0 633 035 Jan 1995 EP
0 652 528 May 1995 EP
0 672 427 Sep 1995 EP
0 683 465 Nov 1995 EP
0 880 936 Dec 1998 EP
1 157 711 Nov 2001 EP
1 174 817 Jan 2002 EP
0 664 102 Apr 2002 EP
1 197 178 Apr 2002 EP
0 830 775 Aug 2002 EP
1 500 025 Apr 2003 EP
2 113 842 Nov 2009 EP
2 228 004 Sep 2010 EP
2 243 506 Oct 2010 EP
2 410 448 Jan 2012 EP
2 742 961 Jun 2014 EP
2 717 919 Sep 1995 FR
2 285 135 Jun 1995 GB
04-161139 Jun 1992 JP
2003-016183 Jan 2003 JP
2003-296173 Oct 2003 JP
2005-021463 Jan 2005 JP
2005-527284 Sep 2005 JP
2005-284846 Oct 2005 JP
2006-047319 Feb 2006 JP
2008-158622 Jul 2008 JP
WO 84001719 May 1984 WO
WO 91016416 Oct 1991 WO
WO 92010985 Jul 1992 WO
WO 92013322 Aug 1992 WO
WO 94005355 Mar 1994 WO
WO 96008755 Mar 1996 WO
WO 96025186 Aug 1996 WO
WO 98012670 Mar 1998 WO
WO 98019263 May 1998 WO
WO 99051003 Oct 1999 WO
WO 00013580 Mar 2000 WO
WO 00053243 Sep 2000 WO
WO 01014974 Mar 2001 WO
WO 01033484 May 2001 WO
WO 01045014 Jun 2001 WO
WO 02005702 Jan 2002 WO
WO 02036044 May 2002 WO
WO 02049153 Jun 2002 WO
WO 02049279 Jun 2002 WO
WO 02069099 Sep 2002 WO
WO 02081015 Oct 2002 WO
WO 02088875 Nov 2002 WO
WO 03006091 Jan 2003 WO
WO 03050917 Jun 2003 WO
WO 03091836 Nov 2003 WO
WO 03094092 Nov 2003 WO
WO 2004060455 Jul 2004 WO
WO 2004070557 Aug 2004 WO
WO 2004070562 Aug 2004 WO
WO 2004072828 Aug 2004 WO
WO 2005036447 Apr 2005 WO
WO 2005050526 Jun 2005 WO
WO 2005057175 Jun 2005 WO
WO 2005066872 Jul 2005 WO
WO 2007087443 Aug 2007 WO
WO 2007117705 Oct 2007 WO
WO 2007127879 Nov 2007 WO
WO 2007127880 Nov 2007 WO
WO 2008067245 Jun 2008 WO
WO 2008082854 Jul 2008 WO
WO 2008088490 Jul 2008 WO
WO 2008097316 Aug 2008 WO
WO 2008103915 Aug 2008 WO
WO 2008124478 Oct 2008 WO
WO 2008134146 Nov 2008 WO
WO 2009016504 Feb 2009 WO
WO 2009023406 Feb 2009 WO
WO 2009023407 Feb 2009 WO
WO 2009023634 Feb 2009 WO
WO 2009036327 Mar 2009 WO
WO 2009049252 Apr 2009 WO
WO 2010017279 Feb 2010 WO
WO 2010033919 Mar 2010 WO
WO 2010053703 May 2010 WO
WO 2010075371 Jul 2010 WO
WO 2010099313 Sep 2010 WO
WO 2010114929 Oct 2010 WO
WO 2010119409 Oct 2010 WO
WO 2010124127 Oct 2010 WO
WO 2010130992 Nov 2010 WO
WO 2010135646 Nov 2010 WO
WO 2010135654 Nov 2010 WO
WO 2010135686 Nov 2010 WO
WO 2011005633 Jan 2011 WO
WO 2011022549 Feb 2011 WO
WO 2012048833 Apr 2012 WO
WO 2012049214 Apr 2012 WO
WO 2012049218 Apr 2012 WO
WO 2012120078 Sep 2012 WO
WO 2012140547 Oct 2012 WO
WO 2012164556 Dec 2012 WO
WO 2012170942 Dec 2012 WO
WO 2013045506 Apr 2013 WO
WO 2014100736 Jun 2014 WO
WO 2014131729 Sep 2014 WO
WO 2014131730 Sep 2014 WO
WO 2017176928 Oct 2017 WO
Non-Patent Literature Citations (103)
Entry
Gomez et al., “CLAM: Connection-Less, Lightweight, and Multiway Communication Support for Distributed Computing”, Computer Science, 1997, vol. 1199, pp. 227-240.
Akridge, Jeannie, “New Pumps Outsmart User Error”, Healthcare Purchasing News, Apr. 2011, pp. 10, http://web.archive.org/web/20110426122450/http://www.hpnonline.com/inside/2011-04/1104-OR-Pumps.html.
Alur et al., “Formal Specifications and Analysis of the Computer-Assisted Resuscitation Algorithm (CARA) Infusion Pump Control System”, International Journal on Software Tools for Technology Transfer, Feb. 2004, vol. 5, No. 4, pp. 308-319.
Aragon, Daleen RN, Ph.D., CCRN, “Evaluation of Nursing Work Effort and Perceptions About Blood Glucose Testing in Tight Glycemic Control”, American Journal of Critical Care, Jul. 2006, vol. 15, No. 4, pp. 370-377.
ASHP Advantage, “Improving Medication Safety in Health Systems Through Innovations in Automation Technology”, Proceedings of Educational Symposium and Educational Sessions during the 39th ASHP Midyear Clinical Meeting, Dec. 5-9, 2004, Orlando, FL, pp. 28.
Beard et al., “Total Quality Pain Management: History, Background, Resources”, Abbott Laboratories, TQPM Survey History, available Feb. 2015 or earlier, pp. 1-3.
Bektas et al., “Bluetooth Communication Employing Antenna Diversity”, Proceedings of Eight IEEE International Symposium on Computers and Communication, Jul. 2003, pp. 6.
Bequette, Ph.D., “A Critical Assessment of Algorithms and Challenges in the Development of a Closed-Loop Artificial Pancreas”, Diabetes Technology & Therapeutics, Feb. 28, 2005, vol. 7, No. 1, pp. 28-47.
Bequette, B. Wayne, Ph.D., “Analysis of Algorithms for Intensive Care Unit Blood Glucose Control”, Journal of Diabetes Science and Technology, Nov. 2007, vol. 1, No. 6, pp. 813-824.
Braun, “Infusomat® Space and Accessories”, Instructions for Use, Nov. 2010, pp. 68. http://corp.bbraun.ee/Extranet/Infusioonipumbad/Kasutusjuhendid/Vanad/Kasutusjuhend-Infusomal_Space(vers688J.lnglise_k).pdf.
Brownlee, Seth, “Product Spotlight: The Plum A+ with Hospira MedNet Infusion System”, PP&P Magazine, Dec. 2005, vol. 2, No. 7, pp. 2.
Cannon, MD et al., “Automated Heparin-Delivery System to Control Activated Partial Thromboplastin Time”, Circulation, Feb. 16, 1999, vol. 99, pp. 751-756.
Cardinal Health, “Alaris® Syringe Pumps” Technical Service Manual, Copyright 2002-2006, Issue 9, pp. 1-88, http://www.frankshospitalworkshop.com/equipment/documents/infusion_pumps/service_manuals/Cardinal_Alaris_-_Service_Manual.pdf.
“CareAware® Infusion Management”, Cerner Store, as printed May 12, 2011, pp. 3, https://store.cerner.com/items/7.
Chen et al., “Enabling Location-Based Services on Wireless LANs”, The 11th IEEE International Conference on Networks, ICON 2003, Sep. 28-Oct. 1, 2003, pp. 567-572.
“Computer Dictionary”, Microsoft Press, Third Edition, Microsoft Press, 1997, pp. 430 & 506.
Crawford, Anne J., MSN, RNC, “Building a Successful Quality Pain Service: Using Patient Satisfaction Data and the Clinical Practice Guideline”, USA, 1995, pp. 1-6.
Crocker et al., “Augmented BNF for Syntax Specifications: ABNF”, Network Working Group, Standards Track, Jan. 2008, pp. 16.
Davidson et al., “A Computer-Directed Intravenous Insulin System Shown to be Safe, Simple, and Effective in 120,618 h of Operation”, Diabetes Care, Oct. 2005, vol. 28, No. 10, pp. 2418-2423.
Davies, T., “Cordless Data Acquisition in a Hospital Environment”, IEE Colloquium on Cordless Computing—Systems and User Experience, 1993, pp. 4.
Dayhoff et al., “Medical Data Capture and Display: The Importance of Clinicians' Workstation Design”, AMIA, Inc., 1994, pp. 541-545.
Diabetes Close Up, Close Concerns AACE Inpatient Management Conference Report, Consensus Development Conference on Inpatient Diabetes and Metabolic Control, Washington, D.C., Dec. 14-16, 2003, pp. 1-32.
East PhD et al., “Digital Electronic Communication Between ICU Ventilators and Computers and Printers”, Respiratory Care, Sep. 1992, vol. 37, No. 9, pp. 1113-1122.
Einhorn, George W., “Total Quality Pain Management: A Computerized Quality Assessment Tool for Postoperative Pain Management”, Abbott Laboratories, Chicago, IL, Mar. 2, 2000, pp. 1-4.
Eskew et al., “Using Innovative Technologies to Set New Safety Standards for the Infusion of Intravenous Medications”, Hospital Pharmacy, 2002, vol. 37, No. 11, pp. 1179-1189.
Philips, “IntelliSpace Event Management and IntelliVue Patient Monitoring”, Release 10, 2011, http://incenter.medical.philips.com/doclib/enc/fetch/2000/4504/577242/577243/577247/582646/583147/8359175/Philips_Patient_Monitoring_and_IntelliSpace_Event_Management_Interoperability.pdf%3fnodeID%3d8508574%26vernum%3d-2, pp. 2.
Felleiter et al., “Data Processing in Prehospital Emergency Medicine”, International journal of Clinical Monitoring and Computing, Feb. 1995, vol. 12, No. 1, pp. 37-41.
Fogt et al., Development and Evaluation of a Glucose Analyzer for a Glucose-Controlled Insulin Infusion System (Biostator®), Clinical Chemistry, 1978, vol. 24, No. 8, pp. 1366-1372.
Gage et al., “Automated Anesthesia Surgery Medical Record System”, International Journal of Clinical Monitoring and Computing, Dec. 1990, vol. 7, No. 4, pp. 259-263.
Galt et al., “Personal Digital Assistant-Based Drug Information Sources: Potential to Improve Medication Safety”, Journal of Medical Library Association, Apr. 2005, vol. 93, No. 2, pp. 229-236.
Gardner, Ph.D. et al., “Real Time Data Acquisition: Recommendations for the Medical Information Bus (MIB)”, 1992, pp. 813-817.
“General-Purpose Infusion Pumps”, Health Devices, EXRI Institute, Oct. 1, 2002, vol. 31, No. 10, pp. 353-387.
Givens et al., “Exploring the Internal State of User Interfaces by Combining Computer Vision Techniques with Grammatical Inference”, Proceedings of the 2013 International Conference on Software Engineering, San Francisco, CA, May 18-26, 2013, pp. 1165-1168.
Glaeser, “A Hierarchical Minicomputer System for Continuous Post-Surgical Monitoring”, Computers and Biomedical Research, Aug. 31, 1975, pp. 336-361.
Goldberg et al., “Clinical Results of an Updated Insulin Infusion Protocol in Critically Ill Patients”, Diabetes Spectrum, 2005, vol. 18, No. 3, pp. 188-191.
“GPS Tracker for Medical Equipment”, http://www.trackingsystem.com/forbusinesses/corporate-trackingsystem/1098-gps-tracker-formedicalequipment.html, Mar. 15, 2015, pp. 2.
Graseby, “Model 3000/500 and Micro 3100/505: Volumetric Infusion Pump”, Technical Service Manual, Graseby Medical Ltd., Apr. 2002, Issue A, pp. 160.
Graseby, “Model 3000/500 and Micro 3100/505: Volumetric Infusion Pump: Illustrated Parts List for Pump Serial Numbers from 3000 to 59,999”, Technical Service Manual, Graseby Medical Ltd., Apr. 2002, Issue A, pp. 71.
Halpern et al., “Changes in Critical Care Beds and Occupancy in the United States 1985-2000: Differences Attributable to Hospital Size”, Critical Care Medical, Aug. 2006, vol. 34, No. 8, pp. 2105-2112.
Hamann et al., “PUMPSIM: A Software Package for Simulating Computer-Controlled Drug Infusion Pumps”, Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 1990, vol. 12, No. 5, pp. 2019-2020.
Hasegawa et al., “On a Portable Memory Device for Physical Activities and Informations of Maternal Perception”, Journal of Perinatal Medicine, 1988, vol. 16, No. 4, pp. 349-356.
Hawley et al., “Clinical Implementation of an Automated Medical Information Bus in an Intensive Care Unit”, Proceedings of the Annual Symposium on Computer Application in Medical Care, Nov. 9, 1988, pp. 621-624.
Hayes-Roth et al., “Guardian: A Prototype Intelligent Agent for Intensive-Care Monitoring”, Artificial Intelligence in Medicine, vol. 4, Dec. 31, 1992, pp. 165-185.
Hospira, GemStar® Pain Management Infusion System 9-084-PR1-2-2, www.hospira.com/products/gemstar_painmanagement.aspx, Jan. 28, 2010, pp. 1-2.
Introducing Abbott TQPM (Total Quality Pain Management), Abbott Laboratories, Abbott Park, IL, May 2000, pp. 1-4.
“Infusion Pump”, Wikipedia.org, https://web.archive.org/web/20140703024932/https://en.wikipeida.org/wiki/Infusion_pump, as last modified Mar. 27, 2014, pp. 3.
Isaka et al., “Control Strategies for Arterial Blood Pressure Regulation”, IEEE Transactions on Biomedical Engineering, Apr. 1993, vol. 40, No. 4, pp. 353-363.
Johnson et al., “Using BCMA Software to Improve Patient Safety in Veterans Administration Medical Centers”, Journal of Healthcare Information Management, Dec. 6, 2004, vol. 16, No. 1, pp. 46-51.
Kent Displays, “Reflex™ Electronic Skins”, Product Brief 25127B, 2009, pp. 2.
Kent Displays, “Reflex Electronic Skins Engineering Evaluation Kit”, 25136A, Mar. 10, 2009.
Lefkowitz et al., “A Trial of the Use of Bar Code Technology to Restructure a Drug Distribution and Administration System”, Hospital Pharmacy, Mar. 31, 1991, vol. 26, No. 3, pp. 239-242.
Lenssen et al., “Bright Color Electronic Paper Technology and Applications”, IDS '09 Publication EP1-2 (Phillips Research), 2009, pp. 529-532.
Leveson, Nancy, “Medical Devices: The Therac-25”, Appendix A, University of Washington, 1995, pp. 49.
Linkens, D.A. “Computer Control for Patient Care”, Computer Control of Real-Time Processes, IEE Control Engineering Series 41, 1990, Ch. 13, pp. 216-238.
Mako Hill et al., The Official Ubuntu Boor, Shoeisha Co., Ltd., 1st Edition, Jun. 11, 2007, pp. 115 to 125.
Marshall, et al., “New Microprocessor-Based Insulin Controller”, IEEE Transactions on Biomedical Engineering, Nov. 1983, vol. BME-30, No. 11, pp. 689-695.
Martino et al., “Automation of a Medical Intensive Care Environment with a Flexible Configuration of Computer Systems”, Proceedings of the Annual Symposium on Computer Application in Medical Care, Nov. 5, 1980, vol. 3, pp. 1562-1568.
Matsunaga et al., “On the Use of Machine Learning to Predict the Time and Resources Consumed by Applications”, 2010 10th IEEE/ACM International Conference on Cluster, Cloud and Grid Computing (CCGrid), May 17-20, 2010, pp. 495-504.
Mauseth et al., “Proposed Clinical Application for Tuning Fuzzy Logic Controller of Artificial Pancreas Utilizing a Personalization Factor”, Journal of Diabetes Science and Technology, Jul. 2010, vol. 4, No. 4, pp. 913-922.
Medfusion™, “Medfusion Syringe Infusion Pump Model 4000”, Operator's Manual, Software Version V1.1, Sep. 2011, pp. 154. http://www.medfusionpump.com/assets/literature/manuals/Operators_Manual_4000_40-5760-51A.pdf.
Metnitz et al., “Computer Assisted Data Analysis in Intensive Care: the ICDEV Project—Development of a Scientific Database System for Intensive Care”, International Journal of Clinical Monitoring and Computing, Aug. 1995, vol. 12, No. 3, pp. 147-159.
Micrel Medical Devices, “MP Daily +” http://web.archive.org/web/20130803235715/http://www.micrelmed.com/index.aspx?productid=9 as archived Aug. 3, 2013 in 1 page.
Moghissi, Etie, MD, FACP, FACE, “Hyperglycemia in Hospitalized Patients”, A Supplement to ACP Hospitalist, Jun. 15, 2008, pp. 32.
Murray, Jr. et al., “Automated Drug Identification System (during surgery)”, IEEE Proceedings of Southeastcon '91, Apr. 7-10, 1991, pp. 265.
Nicholson et al., “‘Smart’ Infusion Apparatus for Computation and Automated Delivery of Loading, Tapering, and Maintenance Infusion Regimens of Lidocaine, Procainamide, and Theophylline”, Proceedings of the Seventh Annual Symposium on Computer Applications in Medical Care, Oct. 1983, pp. 212-213.
Nolan et al., “The P1073 Medical Information Bus Standard: Overview and Benefits for Clinical Users”, 1990, pp. 216-219.
Omnilink Systems, Inc., “Portable Medical Equipment Tracking”, http://www.omnilink.com/portablemedicalequipmenttracking/, Mar. 15, 2015, pp. 2.
O'Shea, Kristen L., “Infusion Management: Working Smarter, Not Harder”, Hospital Pharmacy, Apr. 2013, vol. 48, No. 3, pp. S1-S14.
Package Management in Debian GNU/Linux, Debian GNU/Linux Expert Desktop Use Special, Giutsu-Hyohron Co., Ltd., First Edition, Sep. 25, 2004, pp. 183-185.
Passos et al., “Distributed Software Platform for Automation and Control of General Anaesthesia”, Eighth International Symposium on Parallel and Distributed Computing, ISPDC '09, Jun. 30-Jul. 4, 2009, pp. 8.
Pretty et al., “Hypoglycemia Detection in Critical Care Using Continuous Glucose Monitors: An in Silico Proof of Concept Analysis”, Journal of Diabetes Science and Technology, Jan. 2010, vol. 4, No. 1, pp. 15-24.
Rappoport, Arthur E., “A Hospital Patient and Laboratory machine-Readable Identification System (MRIS) Revisited”, Journal of Medical Systems, Apr. 1984, vol. 8, Nos. 1/2, pp. 133-156.
Ritchie et al., “A Microcomputer Based Controller for Neuromuscular Block During Surgery”, Annals of Biomedical Engineering, Jan. 1985, vol. 13, No. 1, pp. 3-15.
Saager et al., “Computer-Guided Versus Standard Protocol for Insulin Administration in Diabetic Patients Undergoing Cardiac Surgery”, Annual Meeting of the American Society of Critical Care Anesthesiologists, Oct. 13, 2006.
Sanders et al., “The Computer in a Programmable Implantable Medication System (PIMS)”, Proceedings of the Annual Symposium on Computer Application in Medical Care, Nov. 2, 1982, pp. 682-685.
Schilling et al., “Optimizing Outcomes! Error Prevention and Evidence-Based Practice with IV Medications”, a Pro-Ce Publication, Hospira, Inc., Feb. 6, 2012, pp. 56.
Schulze et al., “Advanced Sensors Technology Survey”, Final Report, Feb. 10, 1992, pp. 161.
Scott, et al., “Using Bar-Code Technology to Capture Clinical Intervention Data in a Hospital with a Stand-Alone Pharmacy Computer System”, Mar. 15, 1996, American Journal of Health-System Pharmacy, vol. 53, No. 6, pp. 651-654.
Sebald et al., “Numerical Analysis of a Comprehensive in Silico Subcutaneous Insulin Absorption Compartmental Model”, 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society, Sep. 2-6, 2009, pp. 3901-3904.
Shabot, M. Michael, “Standardized Acquisition of Bedside Data: The IEEE P1073 Medical Information Bus”, International Journal of Clinical Monitoring and Computing, vol. 6, Sep. 27, 1989, pp. 197-204.
Sheppard, Louis, Ph.D., “Automation of the Infusion of Drugs Using Feedback Control”, Journal of Cardiothoracic and Vascular Anesthesia, Feb. 28, 1989, vol. 3, No. 1, pp. 1-3.
Sheppard, Louis, Ph.D., “Computer Control of the Infusion of Vasocactive Drugs”, Annals of Biomedical Engineering, Jul. 1980, vol. 8, No. 4-6, pp. 431-444.
Sheppard, Louis, Ph.D., “The Application of Computers to the Measurement, Analysis, and Treatment of Patients Following Cardiac Surgical Procedures”, The University of Alabama in Birmingham, Oct. 31, 1977, pp. 297-300.
Sheppard, Louis, Ph.D., “The Computer in the Care of Critically Ill Patients”, Proceedings of the IEEE, Sep. 1979, vol. 67, No. 9, pp. 1300-1306.
“Sigma Spectrum: Operator's Manual”, Oct. 2009, pp. 72. http://static.medonecapital.com/manuals/userManuals/Sigma-Spectrum-Operator-Manual-October-2009.pdf.
Simonsen, Michael Ph.D., POC Testing, New Monitoring Strategies on Fast Growth Paths in European Healthcare Arenas, Biomedical Business & Technology, Jan. 2007, vol. 30, No. 1, pp. 1-36.
Siv-Lee et al., “Implementation of Wireless ‘Intelligent’ Pump IV Infusion Technology in a Not-for-Profit Academic Hospital Setting”, Hospital Pharmacy, Sep. 2007, vol. 42, No. 9, pp. 832-840. http://www.thomasland.com/hpj4209-832.pdf.
Slack, W.V., “Information Technologies for Transforming Health Care”, https://www.andrew.cmu.edu/course/90-853/medis.dir/otadocs.dir/03ch2.pdf, Ch. 2, 1995, pp. 29-78.
Smith, Joe, “Infusion Pump Informatics”, CatalyzeCare: Transforming Healthcare, as printed May 12, 2011, pp. 2.
Sodder, Lisa, “A Center Keeps Medicine in Right Hands”, Dec. 4, 1999, pp. 1-2.
Stitt, F.W., “The Problem-Oriented Medical Synopsis: a Patient-Centered Clinical Information System”, Proceedings of the Annual Symposium on Computer Application in Medical Care, 1994, pp. 88-92.
Stokowski, Laura A. RN, MS, “Using Technology to Improve Medication Safety in the Newborn Intensive Care Unit”, Advances in Neonatal Care, Dec. 2001, vol. 1, No. 2, pp. 70-83.
Szeinbach et al., “Automated Dispensing Technologies: Effect on Managed Care”, Journal of Managed Care Pharmacy (JMCP), Sep./Oct. 1995, vol. 1, No. 2, pp. 121-127.
Szolovits et al., “Guardian Angel: Patient-Centered Health Information Systems”, Technical Report MIT/LCS/TR-604, Massachusetts Institute of Technology Laboratory for Computer Science, May 1994, pp. 39.
Van Den Berghe, M.D., Ph.D., et al., “Intensive Insulin Therapy in Critically Ill Patients”, The New England Journal of Medicine, Nov. 8, 2001, vol. 345, No. 19, pp. 1359-1367.
Van Den Berghe, M.D., Ph.D., et al., “Intensive Insulin Therapy in the Medical ICU”, The New England Journal of Medicine, Feb. 2, 2006, vol. 354, No. 5, pp. 449-461.
Van Der Maas et al., “Requirements for Medical Modeling Languages”, Journal of the American Medical Informatics Association, Mar./Apr. 2001, vol. 8, No. 2, pp. 146-162.
Villalobos et al., “Computerized System in Intensive Care medicine”, Medical Informatics, vol. 11, No. 3, 1986, pp. 269-275.
Wilkins et al., “A Regular Language: The Annotated Case Report Form”, PPD Inc., PharmaSUG2011—Paper CD18, 2011, pp. 1-9.
Ying et al., “Regulating Mean Arterial Pressure in Postsurgical Cardiac Patients. A Fuzzy Logic System to Control Administration of Sodium Nitroprusside”, IEEE Engineering in Medicine and Biology Magazine, vol. 13, No. 5, Nov.-Dec. 1994, pp. 671-677.
Yue, Ying Kwan, “A Healthcare Failure Mode and Effect Analysis on the Safety of Secondary Infusions”, Thesis, Institute of Biomaterials and Biomedical Engineering, University of Toronto, 2012, pp. 168.
Yurkonis et al., “Computer Simulation of Adaptive Drug Infusion”, IEEE Transactions on Biomedical Engineering, vol. BME-34, No. 8, Aug. 1987, pp. 633-635.
Zakariah et al., “Combination of Biphasic Transmittance Waveform with Blood Procalcitonin Levels for Diagnosis of Sepsis in Acutely Ill Patients”, Critical Care Medicine, 2008, vol. 36, No. 5, pp. 1507-1512.
Related Publications (1)
Number Date Country
20170331735 A1 Nov 2017 US
Provisional Applications (1)
Number Date Country
61773647 Mar 2013 US
Continuations (1)
Number Date Country
Parent 14198807 Mar 2014 US
Child 15581442 US