Claims
- 1. A macrocyclic complex having the formula: ##STR5## wherein R.sub.1 is selected from the group consisting of CH.sub.2 CH.sub.2 OH, CH.sub.2 CH (CH.sub.3) OH, and CH.sub.2 C(O)NH.sub.2, provided that when R.sub.1 is CH.sub.2 CH.sub.2 OH, M.sup.n+ is Eu.sup.3+ or Gd.sup.3+, provided that when R.sub.1 is CH.sub.2 CH(CH.sub.3)OH, M.sup.n+ is La.sup.3+ or Eu.sup.3+, and provided that when R.sub.1 is CH.sub.2 C(O)NH.sub.2, Mn.sup.+ is La.sup.3+ ; and
- wherein R.sub.2 is selected from the group consisting of hydrogen, alkyl, or aryl.
- 2. A macrocyclic complex according to claim 1, wherein R.sub.1 is CH.sub.2 CH.sub.2 OH and M.sup.n+ is Eu.sup.3+.
- 3. A macrocyclic complex according to claim 1, wherein R.sub.1 is CH.sub.2 CH.sub.2 OH and M.sup.n+ is Gd.sup.3+.
- 4. A macrocyclic complex according to claim 1, wherein R.sub.1 is CH.sub.2 CH(CH.sub.3)OH, and M.sup.n+ is La.sup.3+.
- 5. A macrocyclic complex according to claim 1, wherein R.sub.1 is CH.sub.2 CH(CH.sub.3)OH and M.sup.n+ is Eu.sup.3+.
- 6. A macrocyclic complex according to claim 1, wherein R.sub.1 is CH.sub.2 C(O)NH.sub.2 and M.sup.n+ is La.sup.3+.
- 7. A method of forming a macrocyclic complex, comprising
- reacting a metal ion selected from the group consisting of Eu.sup.3+, Gd.sup.3+, and La.sup.3+, with a non-metallic ion or molecule having the formula: ##STR6## wherein R.sub.1 is selected from the group consisting of CH.sub.2 CH.sub.2 OH, CH.sub.2 CH(CH.sub.3)OH, and CH.sub.2 C(O)NH.sub.2, provided that when R.sub.1 is CH.sub.2 CH.sub.2 OH, the metal ion is Eu.sup.3+ or Gd.sup.3+, provided that when R.sub.1 is CH.sub.2 CH(CH.sub.3)OH, the metal ion is La.sup.3+ or Eu.sup.3+, and provided that when R.sub.1 is CH.sub.2 C(O)NH.sub.2, the metal ion is La.sup.3+ and
- wherein R.sub.2 is selected from the group consisting of hydrogen, alkyl, or aryl
- under conditions which facilitate attachment of the metal ion to the non-metallic ion or molecule, thereby forming the macrocyclic complex.
- 8. A method according to claim 7, wherein R.sub.1 is CH.sub.2 CH.sub.2 OH and the metal ion is Eu.sup.3+.
- 9. A method according to claim 7, wherein R.sub.1 is CH.sub.2 CH.sub.2 OH and the metal ion is Gd.sup.3+.
- 10. A method according to 7, wherein R.sub.1 is CH.sub.2 CH(CH.sub.3)OH and the metal ion is La.sup.3+.
- 11. A method according to 7, wherein R.sub.1 is CH.sub.2 CH(CH.sub.3)OH and the metal ion is Eu.sup.3+.
- 12. A method according to claim 7, wherein R.sub.1 is CH.sub.2 C(O)NH.sub.2 and the metal ion is La.sup.3+.
- 13. A method according to claim 7, wherein said reacting is carried out under anhydrous conditions.
- 14. A method according to claim 13, wherein said reacting is carried out in the presence of trimethyl orthoformate.
Parent Case Info
This application is a continuation of application Ser. No. 08/007,430, filed Jan. 22, 1993, now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
5049667 |
Schaefer et al. |
Sep 1991 |
|
Foreign Referenced Citations (1)
Number |
Date |
Country |
WO 8911868 |
Dec 1989 |
WOX |
Continuations (1)
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Number |
Date |
Country |
Parent |
07430 |
Jan 1993 |
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