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Non-coding nucleic acids modulating the expression of genes, e.g.antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids
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C12N15/113
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C12
Biochemistry
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MICRO-ORGANISMS OR ENZYMES COMPOSITIONS THEREOF PROPAGATING, PRESERVING OR MAINTAINING MICRO-ORGANISMS MUTATION OR GENETIC ENGINEERING CULTURE MEDIA
C12N15/00
Mutation or genetic engineering DNA or RNA concerning genetic engineering, vectors
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C12N15/113
Non-coding nucleic acids modulating the expression of genes, e.g.antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids
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Patents Grants
last 30 patents
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Patent Grant
Use of IRE1α-XBP1 signaling pathway biomarkers for modulating immun...
Patent number
12,227,548
Issue date
Feb 18, 2025
Dana-Farber Cancer Institute, Inc.
Laurie H. Glimcher
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Engineered cascade components and cascade complexes
Patent number
12,227,776
Issue date
Feb 18, 2025
Caribou Biosciences, Inc.
Peter Sean Cameron
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Molecular programming tools
Patent number
12,227,795
Issue date
Feb 18, 2025
President and Fellows of Harvard College
Jocelyn Yoshiko Kishi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compounds and compositions including phosphorothioated oligodeoxynu...
Patent number
12,227,745
Issue date
Feb 18, 2025
City of Hope
Marcin Tomasz Kortylewski
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compounds and methods for modulating SCN2A
Patent number
12,227,746
Issue date
Feb 18, 2025
Ionis Pharmaceuticals, Inc.
Paymaan Jafar-nejad
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
RNA encoding a therapeutic protein
Patent number
12,227,549
Issue date
Feb 18, 2025
CureVac SE
Mariola Fotin-Mleczek
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Altering microbial populations and modifying microbiota
Patent number
12,226,430
Issue date
Feb 18, 2025
SNIPR TECHNOLOGIES LIMITED
Jasper Clube
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Pharmaceutical composition for treatment of diseases associated wit...
Patent number
12,227,743
Issue date
Feb 18, 2025
Osaka University
Fumihiro Sanada
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for inhibiting expression of transthyretin
Patent number
12,227,744
Issue date
Feb 18, 2025
Alnylam Pharmaceuticals, Inc.
Dinah Wen-Yee Sah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modulators of CAS9 polypeptides and methods of use thereof
Patent number
12,227,547
Issue date
Feb 18, 2025
The Regents of the University of California
Jennifer A Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
CasY compositions and methods of use
Patent number
12,227,753
Issue date
Feb 18, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods to restore paternal UBE3A gene expression...
Patent number
12,221,609
Issue date
Feb 11, 2025
University of Connecticut
Stormy Chamberlain
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
RNAi agents for inhibiting expression of HIF-2 alpha (EPAS1), compo...
Patent number
12,221,610
Issue date
Feb 11, 2025
Arrowhead Pharmaceuticals, Inc.
Zhen Li
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Modified pluripotent cells
Patent number
12,221,622
Issue date
Feb 11, 2025
The Regents of the University of California
Sonja Schrepfer
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Multi-targeted single entity conjugates
Patent number
12,221,607
Issue date
Feb 11, 2025
Alnylam Pharmaceuticals, Inc.
Vasant Jadhav
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions and methods for organ-protective expression and modula...
Patent number
12,220,456
Issue date
Feb 11, 2025
Combined Therapeutics, Inc.
Romain Micol
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Compositions, systems, and methods for regulation of hepatitis b vi...
Patent number
12,221,608
Issue date
Feb 11, 2025
TUNE THERAPEUTICS, INC.
Brian Cosgrove
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Systems methods, and compositions for targeted nucleic acid editing
Patent number
12,221,636
Issue date
Feb 11, 2025
The Broad Institute, Inc.
Feng Zhang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Methylene-tetrahydrofolate reductase isoform-based biomarker and me...
Patent number
12,220,416
Issue date
Feb 11, 2025
Rush University Medical Center
Tibor A. Rauch
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Using nucleosome interacting protein domains to enhance targeted ge...
Patent number
12,221,606
Issue date
Feb 11, 2025
Sigma-Aldrich Co. LLC
Fuqiang Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Compositions and methods for expressing factor IX
Patent number
12,214,023
Issue date
Feb 4, 2025
Intellia Therapeutics, Inc.
Jonathan Douglas Finn
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Cell-specific expression of modRNA
Patent number
12,215,336
Issue date
Feb 4, 2025
Icahn School of Medicine at Mount Sinai
Lior Zangi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Therapeutic targets for the correction of the human dystrophin gene...
Patent number
12,214,054
Issue date
Feb 4, 2025
Duke University
Charles A. Gersbach
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Treatment of liver disease with mitochondrial glycerol-3-phosphate...
Patent number
12,215,322
Issue date
Feb 4, 2025
REGENERON PHARMACEUTICALS, INC.
Luca Andrea Lotta
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Therapeutic applications of CPF1-based genome editing
Patent number
12,214,056
Issue date
Feb 4, 2025
Duke University
Charles A. Gersbach
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
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Patent Grant
Methods and compositions for targeted genomic insertion
Patent number
12,215,319
Issue date
Feb 4, 2025
Syngenta Crop Protection AG
Zhongying Chen
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Modulators of diacyglycerol acyltransferase 2 (DGAT2)
Patent number
12,215,321
Issue date
Feb 4, 2025
Ionis Pharmaceuticals, Inc.
Eric E. Swayze
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Grant
Methods and compositions for RNA-directed target DNA modification a...
Patent number
12,215,343
Issue date
Feb 4, 2025
The Regents of the University of California
Jennifer A. Doudna
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
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Patent Grant
Systems and methods for treating hyper-igm syndrome
Patent number
12,214,055
Issue date
Feb 4, 2025
Cecillia Cotta-Ramusino
A61 - MEDICAL OR VETERINARY SCIENCE HYGIENE
Information
Patent Grant
Process for using CRISPR to transfect primordial germ cells in avians
Patent number
12,213,466
Issue date
Feb 4, 2025
COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
Scott Geoffrey Tyack
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Patents Applications
last 30 patents
Information
Patent Application
APOLIPOPROTEIN C3 (APOC3) iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051765
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Kevin FITZGERALD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
iRNA Compositions and Methods for Silencing MYLIP
Publication number
20250051767
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
LUCAS WARD
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
NON-CODING RNA-MEDIATED NEUROLOGICAL DISEASE TREATMENT
Publication number
20250051768
Publication date
Feb 13, 2025
Shanghai GeneMagic BioSciences Co., Ltd.
Haibo ZHOU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antisense Oligonucleotide for Targeting Progranulin
Publication number
20250051772
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Ravi Jagasia
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DIRECT PRODUCTION OF SIRNAS IN SACCHAROMYCES BOULARDII AND PACKAGIN...
Publication number
20250051774
Publication date
Feb 13, 2025
Mercury Bio, Inc.
Tatiana Vinogradova-Shah
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
INHIBIN SUBUNIT BETA E (INHBE) MODULATOR COMPOSITIONS AND METHODS O...
Publication number
20250051779
Publication date
Feb 13, 2025
Alnylam Pharmaceuticals, Inc.
Aimee M. Deaton
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS FOR RNA-PROTEIN TETHERING AND METHODS OF USING
Publication number
20250051788
Publication date
Feb 13, 2025
DONALD DANFORTH PLANT SCIENCE CENTER
R. Keith Slotkin
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATING & PREVENTING E COLI INFECTIONS
Publication number
20250049895
Publication date
Feb 13, 2025
SNIPR Biome ApS
Jakob Krause HAABER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ASGR INHIBITORS
Publication number
20250051457
Publication date
Feb 13, 2025
Amgen Inc.
Paul Nioi
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ANTISENSE OLIGONUCLEOTIDE TARGETING ATN1 MRNA OR PRE-MRNA
Publication number
20250051769
Publication date
Feb 13, 2025
Nippon Shinyaku Co., Ltd.
Takao KAWANO
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDE COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250051778
Publication date
Feb 13, 2025
WAVE LIFE SCIENCES LTD.
Michael John Byrne
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING mRNA SPLICING
Publication number
20250051780
Publication date
Feb 13, 2025
Entrada Therapeutics, Inc.
Ziqing QIAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND MOLECULES FOR RNA INTERFERENCE (RNAi)
Publication number
20250051759
Publication date
Feb 13, 2025
Boehringer Ingelheim International GmbH
Ralph NEUMÜLLER
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
TREATMENT OF NEUROLOGICAL DISEASES USING MODULATORS OF UNC13A GENE...
Publication number
20250051766
Publication date
Feb 13, 2025
QURALIS CORPORATION
SANDRA HINCKLEY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
DNAZYME AND USE THEREOF
Publication number
20250051773
Publication date
Feb 13, 2025
SHANGHAI CANGYU BIOTECHNOLOGY CO., LTD
Hongzhou GU
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
THERAPEUTICS FOR THE TREATMENT OF NEURODEGENERATIVE DISORDERS
Publication number
20250051775
Publication date
Feb 13, 2025
The United States of America, as represented by the Secretary, Department of...
Pietro Fratta
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOUNDS AND METHODS FOR MODULATING GLYCOGEN SYNTHASE 1
Publication number
20250051781
Publication date
Feb 13, 2025
Ionis Pharmaceuticals, Inc.
Huynh-Hoa Bui
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS OF MODULATING LONG NONCODING TRANSCRIPTS A...
Publication number
20250051776
Publication date
Feb 13, 2025
HAYA Therapeutics SA
Samir OUNZAIN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR MODULATING INTERFERON REGULATORY FACTO...
Publication number
20250051393
Publication date
Feb 13, 2025
Entrada Therapeutics, Inc.
Ziqing QIAN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
CELLS COMPRISING A SUPPRESSOR OF GENE EXPRESSION AND/OR A SYNTHETIC...
Publication number
20250049854
Publication date
Feb 13, 2025
Arsenal Biosciences, Inc.
Aaron Cooper
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
COMPOSITIONS AND METHODS FOR REGULATING PRODUCTION OF AN ANTIBODY L...
Publication number
20250051424
Publication date
Feb 13, 2025
Wyvern Pharmaceuticals Inc.
Bradley G. THOMPSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
FERROCHELATASE INHIBITORS AND METHODS OF USE
Publication number
20250049804
Publication date
Feb 13, 2025
Indiana University Research and Technology Corporation
Timothy W. CORSON
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
Antisense Compounds Targeting Genes Associated with Cystic Fibrosis
Publication number
20250049838
Publication date
Feb 13, 2025
ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE
Michelle L. Hastings
A01 - AGRICULTURE FORESTRY ANIMAL HUSBANDRY HUNTING TRAPPING FISHING
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Patent Application
COMPOSITIONS COMPRISING THERAPEUTIC NUCLEIC ACID AND SAPONIN FOR TH...
Publication number
20250051770
Publication date
Feb 13, 2025
Sapreme Technologies B.V.
Miriam Verena BUJNY
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
MULTIVALENT CARGO-CARRYING COMPLEXES AND USES THEREOF
Publication number
20250051771
Publication date
Feb 13, 2025
AstraZeneca AB
Lars Anders DAHLÉN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
OLIGONUCLEOTIDES FOR MODULATING TAU EXPRESSION
Publication number
20250051777
Publication date
Feb 13, 2025
HOFFMANN-LA ROCHE INC.
Peter HAGEDORN
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
METHODS AND COMPOSITIONS RELATED TO RNA-TARGETED RHO SMALL GTPase R...
Publication number
20250051782
Publication date
Feb 13, 2025
THE TEXAS A&M UNIVERSITY SYSTEM
Jiang Chang
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
ATTENUATED ORTHOMYXOVIRUS-BASED VECTOR PLATFORM
Publication number
20250043282
Publication date
Feb 6, 2025
NEW YORK UNIVERSITY
Benjamin tenOever
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
PROCESSES FOR PREPARING PHOSPHORODIAMIDATE MORPHOLINO OLIGOMERS VIA...
Publication number
20250043283
Publication date
Feb 6, 2025
Sarepta Therapeutics, Inc.
Kyle A. Totaro
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...
Information
Patent Application
SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
Publication number
20250043279
Publication date
Feb 6, 2025
Alnylam Pharmaceuticals, Inc.
Mark K. Schlegel
C12 - BIOCHEMISTRY BEER SPIRITS WINE VINEGAR MICROBIOLOGY ENZYMOLOGY MUTATION...