Cho et al, PNAS, USA, 95, pp. 3752-3757 (1998).* |
Klein, Joachim, “A New Family of DNA binding proteins includes putative transcriptional regulators of the Antirrhinum majus floral meristem identity gene SQUAMOSA”, 1996, vol. 250, pp. 7-16. |
Thiel, Karl A., “Understanding Your Inner Transistor Radio: The Large-Scale Study of Gene Regulation”, http://www.doubletwist.com/news/co.../article.jhtml?section=weekly01name=weekly011, May 26, 2000. |
Van Brunt, Jennifer (Editor), “Systems Biology in the Post-Genomics Era”, http://www.recap.com/signal.../0A9F0F7DD2D01BBE88256874004C143C?, Jan. 28, 2000. |
Takahashi, Nobuaki et al., “High-density cDNA filter analysis of the expression profiles of the genes preferentially expressed in human brain”, Gene, Jun. 9, 1995, vol. 164, pp. 219-227. |
Zhoa, Nanding et al., “High-density cDNA filter analysis: a novel approach for large-scale, quantitative analysis of gene expression”, Gene, Jan. 2, 1995, vol. 156, pp. 207-213. |
Pisetsky, David S. et al., “Binding Specificity of a Monoclonal Anti-DNA Antibody”, Molecular Immunology, Sep. 16, 1981, vol. 19, No. 5, pp. 645-650. |
Broude, Natalia E. et al., “Enhanced DNA sequencing by hybridization”, Proc. Natl. Acad. Sci., Apr. 1994, vol. 91, pp. 3072-3076. |
Kallioniemi, Anne et al., “Comparitive Genomic Hybridization for Molecular Cytogenic Analysis of Solid Tumors”, Science, Oct. 30, 1992, vol. 258, pp. 818-821. |
Velculescu, Victor E. et al., “Serial Analysis of Gene Expression”, Science, Oct. 20, 1995, vol. 270, pp. 484-487. |
Nallur, G.N. et al., “Multiplex Selection Technique (MuST): An Approach to clone trascription factor binding sites”, Proc. Natl. Acad. Sci. , Feb. 1996, vol. 6, No. 93, pp. 1184-1189. |
Meier-Ewert, Sebastian et al., “An automated approach to generating expressed sequence catalogues”, Nature, Jan. 28, 1993, vol. 361, pp. 375-376. |
Barringer, Kevin J. et al., “Blunt-end and single-strand ligations by Escherichia coli ligase: influence on an in vitro amplification scheme”, Gene, Dec. 6, 1989, vol. 89, pp. 117-122. |
Bussow, Konrad et al., “A method for global protein expression and antibody screening on high-density filters of an arrayed cDNA library”, Nucleic Acids Research, Sep. 10, 1998, vol. 26, No. 21, pp. 5007-5008. |
Vaughan, Tristan J. et al., “Human Antibodies with Sub-nanomolar Affinities Isolated from a Large Non-immunized Phage Display Library”, Nature Biotechnology, Mar. 1996, vol. 14, pp. 309-314. |
Greenberg, Michael E. et al., “Stimualtion of 3T3 cells induces transcription of the c-fos proto-oncogene”, Nature, Oct. 4, 1984, vol. 311, pp. 433-438. |
Ward, E. Sally et al., “Binding activities of a repertoire of single immunoglobulin variable domains secreted from Escherichia coli”, Nature, Oct. 12, 1989, vol. 341, pp. 544-546. |
Prooijen-Knegt, A. C. Van et al., “In Situ Hybridization of DNA Sequences in Human Metaphase Chromosomes Visualized by an Indirect Fluorescent Immunocytochemical Procedure”, Experimental Cell Research, Mar. 10, 1982, vol. 141, pp. 397-407. |
Coutlee, Francois et al., “Nonisotopic Detection of RNA in an Enzyme Immunoassay Using a Monoclonal Antibody against DNA-RNA Hybrids”, Analytical Biochemistry, Feb. 13, 1989, vol. 181, pp. 153-162. |
Lee, Youn-Ho et al., “Reusable cDNA Libraries Coupled to Magnetic Beads”, Analytical Biochemistry, 1992, vol. 206, pp. 206-210. |
Lennon, Gregory G. et al., “Hybridization analyses of arrayed cDNA libraries”, Perspectives, Oct. 1991, vol. 7, No. 10, pp. 314-317. |
Boguslawski, Sophie J. et al., “Characterization of monoclonal antibody to DNA RNA and its application to immunodetection of hybrids”, Journal of Immunological Methods, Dec. 17, 1985, vol. 89, pp. 123-130. |
Eberwine, James et al., “Analysis of gene expresion in single live neurons”, Proc. Natl. Acad. Sci., Apr. 1992, vol. 89, pp. 3010-3014. |
Guatelli, John C. et al., “Isothermal, in vitro amplification of nucleic acids by a multienzyme reaction modeled after retroviral replication”, Proc. Natl. Acad. Sci., Mar. 1990, vol. 87, pp. 1874-1878. |
Marshall, Christopher, J., “Tumor Suppressor Genes”, Cell, Jan. 25, 1991, vol. 64, pp. 313-326. |
Wu, Dan Y. et al., “The Ligation Amplification Reaction (LAR)—Amplification of Specific DNA Sequences Using Sequential Rounds of Template-Dependent Ligation”, Genomics, Dec. 28, 1988, vol. 4, pp. 560-569. |
Palazzolo, Michael J. et al., “Phage lambda cDNA cloning vectors for subtractive hybridization, fusion-protein synthesis and Cre-loxP automatic plasmid subcloning”, Gene, Oct. 5, 1989, vol. 88, pp. 25-36. |
Nguyen, Catherine et al., “Differential Gene Expression in the Murine Thymus Assayed by Quantitative Hybridization of Arrayed cDNA Clones”, Genomics, Jun. 23, 1995, vol. 29, pp. 207-216. |
Fornace, Albert J. et al., “DNA damage-inducible transcripts in mammalian cells”, Proc. Natl. Acad. Sci., Dec. 1988, vol. 85, pp. 8800-8804. |
Schena, Mark et al., “Parallel human genome analysis: Microarray-based expression monitoring of 1000 genes”, Proc. Natl. Acad. Sci., Oct. 1996, vol. 93, pp. 10614-10619. |
Chee, Mark et al., “Accessing Genetic Information with High-Density DNA Arrays”, Science, Oct. 25, 1996, vol. 274, pp. 610-614. |
Campbell, David A. et al., “Phosphonate Ester Synthesis Using a Modified Mitsunobu Condensation”, J. Org. Chem., 1994, vol. 59, No. 3, pp. 658-660. |
Viscidi, Raphael P. et al., “Monoclonal Antibody Solution Hybridization Assay for Detection of Human Immunodeficiency Virus Nucleic Acids”, Journal of Microbiology, Jan. 1989, vol. 27, No. 1, pp. 120-125. |
Van Gelder, Russell N. et al., “Amplified RNA synthesized from limited quantities of heterogeneous cDNA”, Proc. Natl. Acad. Sci., Mar. 1990, vol. 87, pp. 1663-1667. |
DeWitt, Sheila Hobbs et al., “Diversomers: An approach to nonpeptide, nonoligomeric chemical diversity”, Proc. Natl. Acad. Sci., Aug. 1993, vol. 90, pp. 6909-6913. |
Sasmor, Henri et al., “Symmetric lac operator derivatives: effects of half-operator sequence and spacing on repressor affinity”, Gene, Jan. 7, 1990, vol. 89, pp. 1-6. |
Oelgeschlager, Thomas et al., “Probing the function of individual amino acid Residues in the DNA binding site of the EcoRI restriction endonuclease by analysing the toxicity of genetically engineered mutants”, Gene, Nov. 10, 1989, vol. 89, pp. 19-27. |
Dignam, John David et al., “Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei”, Nucleic Acids Research, Jan. 18, 1983, vol. 11, pp. 1475-1489. |
Southern, E. M. et al., “Arrays of complementary oligonucleotides for analysing the hybridisation behaviour of nucleic acids”, Nucleic Acids Research, Mar. 9, 1994, vol. 22, No. 8, pp. 1368-1373. |
Huse, William D. et al., “Generation of a Large Combinatorial Library of the Immunoglobulin Repertoire in Phage Lambda”, Science, Dec. 8, 1989, vol. 246, pp. 1275-1281. |
Theillet, Charles, “Full speed ahead for tumor screening”, Nature Medicine, Jul. 1998, vol. 4, No. 7, pp. 767-768. |
Kononen, Juha et al., “Tissue microarrays for high-throughput molecular profiling of tumor specimens”, Nature Medicine, Jul. 1998, vol. 4, No. 7, pp. 844-847. |
Meier-Ewert, Sebastian et al., “An automated approach to generating expressed sequence catalogues”, Nature, Jan. 28, 1993, vol. 361, pp. 375-376. |
Liang, Rui et al., “Parallel Synthesis and Screening of a Solid Phase Carbohydrate Library”, Science, Nov. 29, 1996, vol. 274, pp. 1520-1522. |
Uetz, Peter et al., “A comprehensive analysis of protein—protein interactions in Saccharomyces cerevisiae,”, Nature, Feb. 10, 2000, vol. 403, pp. 623-627. |
Zehetner, Gunther, “The Reference Library System—sharing biological material and experimental data”, Nature, Feb. 3, 1994, vol. 367, pp. 489-491. |
Landegren, Ulf et al., “A Ligase-Mediated Gene Detection Technique”, Science, Aug. 1988, vol. 241, pp. 1077-1080. |
Kuijpers, W. H. A. et al., “Synthesis of well-defined phosphate-methylated DNA fragments: the application of potassium carbonate in menthanol as deprotecting reagent”, Nucleic Acids Research, Jun. 13, 1990, vol. 18, No. 17, pp. 5197-5205. |
Houghten, Richard A. et al., “Generation and use of synthetic peptide combinatorial libraries for basic research and drug discovery”, Nature, Nov. 7, 1991, vol. 354, pp. 84-86. |
Kohler, G. et al., “Continuous cultures of fused cells secreting antibody of predefined specificity”, Nature, Aug. 7, 1975, vol. 256, pp. 495-497. |
Rudkin, George et al., “High resolution detection of DNA-RNA hybrids in situ by indirect immunofluorescence”, Nature, Feb. 3, 1977, vol. 265, pp. 472-473. |
Kwoh, D. Y. et al., “Transcription-based amplification system and detection of amplified human immunodeficiency virus type 1 with a bead-based sandwich hybridization format”, Proc. Natl. Acad. Sci., Feb. 1989, vol. 86, pp. 1173-1177. |
Meier-Ewer, Sebastian et al., “Comparitive gene expression profiling by oligonucleotide fingerprinting”, Nucleic Acids Research, Mar. 8, 1998, vol. 26, No. 9, pp. 2216-2223. |
Gress, Thomas et al., “Hybridization fingerprinting of high-density cDNA-library arrays with cDNA pools derived from whole tissues”, Mammalian Genome, Jul. 2, 1992, vol. 3, pp. 609-619. |
Lockhart, David J. et al., “Expression monitoring by hyridization to high-density oligonucleotide arrays”, Nature Biotechnology, Dec. 1996, vol. 14, pp. 1675-1680. |
Schena, Mark et al., “Quantitative Monitoring of Gene Expression Patterns with a Complimentary DNA Microarray”, Science, Oct. 20, 1995, vol. 270, pp. 467-470. |
Phimster, Bette, “Going global”, Nature Genetics, Jan. 1999, vol. 21, No. 1, pp. 1-50. |
Englert, Chad R. et al., “Layered Expression Scanning: Rapid Molecular Profiling of Tumor Samples”, Cancer Research, Mar. 15, 2000, vol. 60, pp. 1526-1530. |
Taylor, Laura C. et al., “Application of a High-Density Optical Micowell Arrays in a Live-Cell Biosensing System”, Analytical Biochemistry, May 14, 1999, vol. 26, pp. 132-142. |
Arenkov, Pavel et al., “Protein Microchips: Use for Immunoassay and Enzymatic Reactions”, Analytical Biochemistry, Jun. 7, 1999, vol. 278, pp. 123-131. |