Patent Grant
10519945
This invention has for object a method for generating a flow, as well as a device for generating a flow suitable for the implementation of the method.
The field of the invention relates to the field of devices for controlling and/or generating a flow of fluid, and more particularly micro-pumps or micro-mixers.
The invention shall have a particular application as microTas for Lab-on-a-Chip applications.
It is known to use mechanical micro-pumps that use mobile parts, such as an oscillating membrane, a turbine or a piston, exerting a mechanical action directly on the fluid in motion.
Conventionally in particular in a device with a membrane, the design of these pumps involves the presence of a pumping chamber that compresses and/or expands the fluid circulating between the inlet and the outlet.
Such a device for generating flows is known for example in document U.S. Pat. No. 5,718,567 which describes a micro-pump with membrane comprising a pumping chamber connected to a suction channel and to a discharge channel, an intake valve on one end of the membrane, and an outlet valve on the other end of the membrane, a mechanism for driving the membrane, with the membrane comprising a deformable wall of the pumping chamber.
Such a micro-pump requires the presence of said pumping chamber and of valves in order to obtain the compression and the expansion of the fluid, which involves a device that is relatively cumbersome and generally complex to integrate.
When the pumping chamber is under negative pressure under the action of the membrane, the intake valve is open and the outlet valve is closed, causing the intake of the fluid from the feed channel to the pumping chamber. When the pumping chamber is in overpressure, under the action of the membrane, the intake valve is closed and the outlet valve is open, causing the discharge of the fluid to the discharge channel.
Generating the flow involves two crossings of the membrane, a first crossing from the feed channel to the pumping chamber by the intermediary of the intake valve and a second crossing from the pumping chamber to the discharge channel by the intermediary of the outlet valve.
Another disadvantage of such a micro-pump is that it can generate the flow only in a single direction, with the valves preventing the operation of the pump in the opposite direction.
Also, the design of such a micro-pump is complex and its manufacturing costs are high.
It is also known from document WO 02/097270 A1 a micro-pump, that comprises:
In this anteriority, the flow of fluid from the inlet to the outlet is obtained, by actuating in phase opposition the perforated element and the shutter.
It is also known from document DE 10 2008 004147 a micro-pump comprising a membrane extending above a channel of fluid (10), with the membrane comprising a component of fluid (marked 4) having a passage through the membrane.
According to this document, the mechanics of the component of fluid marked 4 is such that the resistance to the flow through the passage according to a deflection of the membrane according to a first direction is greater than the resistance to the flow of the passage according to a deflection of the membrane according to a second direction and in such a way as to generate a net flow rate of fluid according to said first direction when the membrane is actuated according to a back-and-forth movement.
In this anteriority, the “component of fluid” is the essential element that makes it possible to generate the flow in a given direction: such a pump only has a single direction of operation, namely said first direction, and therefore cannot be bidirectional.
According to the example of
According to other examples shown, in particular in
Document US 2006/232167 A1 relates to a piezoelectric diaphragm having a membrane comprising an opening, marked 25.
This opening is provided with a flap valve arranged to close or open the opening in response to the movements of the diaphragm.
In this anteriority, the flow of the fluid through the membrane is obtained thanks to the valve that authorises a circulation of fluid in a single direction, from the feed chamber, marked 61 to the outlet chamber marked 65.
This valve can be an accessory inserted into the opening. Alternatively, the accessory can be a ball valve, or a precision orifice accessory.
In this anteriority, each accessory is a rigid element having a non-deformable orifice.
All the micro-pump devices of the anteriorities of documents WO 02/097270 A1, DE 10 2008 004147 or US2006/232167 each use a membrane actuated by a back-and-forth movement and making it possible to generate a flow, according to a net flow rate, at least in a first direction through the membrane.
In these devices, a regulating device is always required and associated with the membrane in order to impose a direction of circulation to the fluid, namely:
It is also known from document EP 2 306 019 A1 a micro fan, that comprises (see claim 1):
Such a device according to this anteriority is suitable only for a compressible fluid and is not suited for generating a flow using an incompressible fluid, such as for example water.
According to this anteriority (paragraphs 36 and 37), the vibrations of the actuator marked 50 cause the vibration of the first wall marked 30 and generates in turn a fluctuation in the pressure in the chamber of the central space marked 21. Because of the bottleneck 23, this fluctuation is substantially dissipated through the second opening marked 11. As the flow of fluid in the central space is substantial, the internal pressure in the central space marked 21 is less than the pressure of the feed passage marked 22, which generates a pressure gradient creating a flow of fluid from the feed passage 22 to the central space 21.
This is a device with an extremely complex and expensive structure.
The invention has in particular for objective to overcome the various disadvantages of these known techniques.
More precisely, an objective of the invention is to provide a device that allows for easier integration and that makes the devices more compact, and according to the desire of the inventor, not requiring a pumping chamber and valves in order to operate, even generally, any other flow rate regulating device, and in particular those taught in the aforementioned anteriorities.
Another objective of the invention is, at least in one particular embodiment, to propose a device of simple design and which by the same occasion reduces the manufacturing costs.
Another objective of the invention is, at least in one particular embodiment, to propose a device that makes it possible to obtain better performance.
Another objective of the invention, is at least in one embodiment to propose a method for generating a flow of fluid.
These objectives, as well as others which shall appear more clearly in what follows, are achieved according to the invention using a method for generating a flow of fluid implemented in a device comprising a membrane provided with at least one hole as well as means generating back-and-forth movements, wherein a flow is generated through the membrane by actuating said membrane, at least on said at least one hole, according to a mode of deformation of said at least one hole causing said at least one hole to open and close and disturbing the fluid in order to generate said flow through the membrane, in a given direction (i.e. to suction or to discharge).
The method implemented makes it possible to generate a flow par a single crossing of the fluid through the membrane, advantageously without requiring a pumping chamber to compress or expand the fluid, or any valve and such as encountered in prior art known through document U.S. Pat. No. 5,718,567.
According to current understanding, the controlled deformation of the membrane, at least on said at least one hole allows for the implementation of a mode of deformation of said at least one hole which generates a flow of fluid.
According to the invention, it is the mode of deformation of the hole resulting from the actuating of the membrane that causes the flow of the fluid, and as such the generating of a net flow rate through the membrane in a given direction, to “discharge” or to “suction”: this hole is not associated with any added flow-regulating device such as a valve (or other element shutting off the hole in order to impose a direction of flow), nor does it have a geometry that is proper or an accessory imposing a preferred direction of circulation of fluid through the membrane.
Also a first advantage of the method according to the invention is that it requires, for its implementation, only a device with an extremely simple structure, comprising solely for essential elements, on the one hand, the membrane provided with said at least one hole (deformable), and on the other hand, means generating back-and-forth movement associated with this membrane.
According to optional characteristics of the invention, taken individually or in combination:
The invention also relates to a device for generating a flow of fluid, suitable for the implementation of the method, and comprising:
in such a way as to allow for the generating of a flow through the membrane by exciting the membrane in such a way as to actuate and deform said at least one hole according to a mode of deformation of said at least one hole and generating a flow through the membrane in a given direction.
According to characteristics of the invention, taken individually or in combination:
Other characteristics and advantages of the invention shall appear more clearly when reading the following description of a particular embodiment of the invention, provided solely as a non-limiting example for the purposes of information, and the annexed drawings, among which:
As mentioned hereinabove, the general principle of the invention is therefore based on the implementation of a method for generating a flow of fluid implemented in a device comprising a membrane 2 provided with at least one hole 20 as well as means 4 for generating back-and-forth movements.
According to the invention, a flow is generated through the membrane by actuating said membrane, at least on said at least one hole, according to a mode of deformation of said at least one hole causing the openings and closings of said at least one hole and disturbing the fluid in order to generate said flow.
The method implemented makes it possible to generate a flow by a single crossing of the fluid through the membrane, not two as in document U.S. Pat. No. 5,718,567.
Advantageously, the method according to the invention does not require a pumping chamber, or valves, to compress or expand the fluid and such as encountered in prior art known through document U.S. Pat. No. 5,718,567.
According to the invention, it is the mode of deformation of the hole resulting from the actuating of the membrane that causes the flow of the fluid, and as such the generating of a net flow rate through the membrane in a given direction, “as discharge” or as “suction”: this hole is not associated with any added flow-regulating device such as a valve (or other element shutting off the hole in order to impose a direction of flow), nor does it have any proper geometry or an accessory imposing a preferred direction of circulation of fluid through the membrane.
Surprisingly, the inventors have as such observed, that such a simply perforated membrane (i.e. without a flow-regulating device such as a valve or other shutter, or even having a geometry of the hole imposing a preferred direction of flow) made it possible, when deformed according to a mode of deformation of the hole, to generate a circulation of fluid, in a single direction (as “discharge” or as “suction”). Such an observation therefore goes against the prejudice taught by prior art (in particular WO 02/097270 A1, DE 102008 004147 or US2006/232167) according to which a flow-regulating device (valve or other shutter), or a specific geometry of the hole (“of section as a diffuser” according to document DE 10 2008 004147) is required to generate a flow through the membrane according to a given direction.
Furthermore, the inventors have observed that it was possible to change the direction of circulation of the fluid (from the “suction” direction to the “discharge” direction or inversely) by changing the excitation on the means generating back-and-forth movements, and even the mode of deformation of the hole, in particular in that said at least one hole in the membrane does not have any preferred direction of flow, and is devoid of a flow-regulating device.
Also a first advantage of the method according to the invention is that it requires, for its implementation, only a device with an extremely simple structure, comprising solely for essential elements, on the one hand, the membrane provided with said at least one hole (deformable), and on the other hand, means generating back-and-forth movement associated with this membrane. Furthermore and if the hole can have different possible shapes, the latter is not configured to impose a preferred direction of flow through the membrane.
According to an embodiment the back-and-forth movements are periodic movements, such as for example movements of oscillations. It is also possible to generate a flow of fluid thanks to pseudoperiodic movements or aperiodic movements.
According to an embodiment, back-and-forth movements of the membrane 2 are generated which create movements of bending of the membrane 2. Alternatively, movements of the membrane are generated that create torsion movements of the membrane, or movements of tension and/or movements of compression of the membrane. The movements generated can again be a combination of all or of any of these different movements. The mode of deformation (bending and/or torsion and/or compression and/or tension) makes it possible, in combination with the openings and closings of said at least one hole, to generate the flow of fluid through the membrane 4.
Said at least one hole 20 authorises a circulation of fluid through the membrane, in a first direction, from one side to the other of the membrane, and in a second opposite direction. To this effect, this hole is not associated with any flow-regulating device such as a valve, valves, or other shutting-off system, nor does it have a geometry that is proper that creates a least resistance of flow in a given direction, and as such a preferred direction of flow through the membrane.
Advantageously, it is perhaps possible to change the direction of circulation of the fluid through the membrane by the controlling of the excitation of the means generating back-and-forth movements. The direction of the circulation of the fluid can for example be changed by modifying the mode of deformation of said membrane 2. For example, as a non-limiting example, the direction of circulation of the fluid can be changed by varying the oscillation frequency of the membrane 2. It is also possible to change the direction of circulation by applying a voltage offset, with a positive or negative sign. It is as such possible to operate the micro-pump as discharge (resp. as suction), with the circulation of the fluid passing through the membrane according to a first direction, then by modifying the excitation of the means generating back-and-forth movements, even the mode of deformation of the hole, to operate the micro-pump as suction (resp. as discharge), with the circulation of fluid passing through the membrane according to a second direction (opposite the first direction).
According to an embodiment, the means for generating 4 back-and-forth movements include electro-active or magneto-active means, such as for example an electrostatic actuator, an electromagnetic or piezoelectric actuator. The means 4 for generating back-and-forth movements are excited by a variable current signal. Possibly an offset is applied on the voltage positively or negatively, in such a way as to generate the flow.
In a particular case, the hole or holes are of a submillimetric or millimetric dimension. Said hole 20 can be a slot. The width of the slot can be between 1 micron and 500 microns. The length of said slot can be between 1 micron and 2,000 microns. In the entire application the dimensions of the hole are those of holes when the membrane is not subjected to a constraint. Among all of the patterns possible, the pattern of said at least one hole 20 can be chosen from a pattern as H (
According to an embodiment shown in
According to an embodiment, the means generating back-and-forth movements are separate from the membrane and cooperate with said membrane to actuate and deform the membrane at least on said hole. Alternatively, the membrane can be active, comprising an ionic polymer excited by electrodes. Again, the membrane can be active, comprising a flexible material loaded with magnetic nano-materials (for example Fe, FexOy, permanent magnet, etc.) or dielectric (for example LiNBO3, SiO2, etc.), or metal (for example carbon nanotube, graphene, etc.). The introduction of these materials makes it possible to render said membrane active intrinsically and can be used for example as an active flexible piezoelectric, or dielectric, or ionic, or magnetic material.
More precisely, such a device intended for the implementing of the method according to the invention can comprise:
Such a device allows for the generating of a flow through the membrane by deforming the membrane 2 in such a way as to actuate said at least one hole 20 according to a mode of deformation, in order to cause openings of said at least one hole 20 during movements.
According to an embodiment, the device comprises a third portion 3 made of rigid material, such as silicon for example, connected to one of the faces of the mobile portion of the membrane 2, said third portion 3 being arranged at the centre of the recess 10.
The third portion is of a dimension less than that of the recess 10 in such a way as to form an inter-space 30 between said first portion and said third portion 3, and in such a way as to form a mobile portion comprising the mobile portion of the membrane 2 and the third portion 3 in a particular configuration at the centre of the recess 10.
The means 4 for generating movements are able to cooperate with said third portion 3 in such a way as to actuate the mobile portion as well as the hole or the mobile portion as well as the hole or holes 20 of the membrane 2 on the inter-space.
The mode of operation of the device can be dual, i.e. the membrane 2 is able, during back-and-forth movements of the mobile portion 31, to circulate a fluid in both directions, with the device making it possible to carry out a suction as well as a discharge of the fluid. A modification of the device is not required here in order to modify the direction of circulation of the fluid. A bidirectional mode of operation can also be spoken of To this effect, said at least one hole 20 must authorise a circulation of fluid through the membrane, in a first direction, from one side to the other of the membrane, and in a second opposite direction.
Moreover, the device is able to circulate a fluid through the membrane 2 during movements of the mobile portion, and is able, more preferably, to prohibit the circulation of the fluid when the mobile portion is at rest.
As can be seen in
According to another embodiment of the invention, said at least one hole 20 is arranged on corners of said third portion 3. Of course, the position of the hole or holes 20 can be modified according to need.
The structure of the device is defined by the length and the width of the fixed portion 1, which can, by way of a non-limiting example, vary between 2 mm and 20 mm, as well as by the length and the width of the flexible membrane 2, which can vary between 2 mm and 20 mm also.
The structure of the device is also defined by the length and the width of the third portion 3, which can vary between 500 μm and 10 000 μm, and by the length and the width of the recess 10, which can vary between 500 μm and 10,000 μm.
The thickness of the fixed portion 1, varies between 100 μm and 10,000 μm, that of the membrane 10 made of flexible elastomer, varies between 10 μm and 200 μm, and that of the third portion 3, varies between 0 and 10,000 μm.
According to an embodiment of the invention, the width of said at least one hole 20 is between 1 μm and 500 μm and the length of said at least one hole is between 1 μm and 2000 μm,
As such, the choice of the width of the recess 10, of the third portion 3, as well as of the thickness of the membrane 2 results from a compromise between the flexibility of the membrane 2 desired and its robustness during the actuating. A membrane 2 that is not very wide and thick will be more resistant but will not make it possible to obtain substantial displacement of the membrane 2. Inversely, a membrane 2 that is thin and wide will be flexible but not very resistant to the forces of traction and torsion applied to the membrane 2.
Moreover, the length and the width of said hole 20 are determining factors for the performance of the device, in particular for the flow rate and the pressures generated. For example, a hole 20 of substantial size, for example 500 μm wide and 2000 μm long, will make it possible to obtain high flow rates.
As can be observed in
Such as shown in
In
According to the preceding embodiment, the corners of the rectangular inter-space are rounded in order to limit the constraints implied by angular corners during the oscillation of the membrane 2. Indeed, by retaining a right angle, the membrane 2 is exposed to a risk of tearing on said corners.
According to a particular embodiment of the invention, the excitation signal of the membrane 2 is varied, via means for controlling acting on the means 4 for generating back-and-forth movements, in such a way as to change the direction of circulation of the fluid. For example, the direction of circulation of the fluid is changed by varying the excitation frequency of the membrane.
According to a first prototype, and according to the observations of the inventor, a suction/discharge change was measured, by way of a non-limiting example around 225-275 Hz. In this frequency range, the main vibration mode observed is a so-called torsion mode, with a so-called bending mode being observed at the other frequencies.
The inventor has also observed that the position of the hole or holes 20 influences the performance of the device. Indeed, when the holes 20 are arranged on corners, the torsion mode is predominant around 225-275 Hz, with the device then operating as discharge. Inversely, outside of this range of frequencies, the device operates as suction.
The position of the holes 20 on corners thus makes it possible to obtain better performance in torsion mode, with the openings 20 opening more substantially.
Likewise, the inventor observed that in the case of holes 20 arranged at mid-distance between the edge of the first portion 1 and the edge of the third portion 3, the performance in suction is better. Indeed, the bending mode allows for a greater clearance and a better opening of the holes 20 arranged at mid-distance between the edge of the first portion 1 and the edge of the third portion 3.
The inventor moreover observed two peaks of resonance located at around 100 Hz and 175/200 Hz, with the resonance peaks generating a more substantial deflection of the membrane 2 and therefore an increase in the flow rate. According to an embodiment, it is possible to excite the membrane 2 at its resonance frequency or frequencies.
It is understood that the frequencies and other parameters mentioned hereinabove and hereinbelow are mentioned by way of a non-limiting example, for a given prototype. These parameters (the frequencies for the change in regime and the resonance frequencies in particular) depend on the parameters of the device such as the material used for the membrane, the dimensions of the membrane (thickness in particular), the tension exerted on the membrane and the weight of the mobile portion in particular, and are specific to the device carried out.
According to another particular embodiment of the invention, the means for generating oscillations 4 include electromagnetic means that are excited by an alternating current signal and whereon an offset is applied on the voltage in such a way as to change the operation mode of the device, i.e. change the direction of circulation of the fluid.
For example, by way of a non-limiting example, an offset of 125 mV on a voltage of 500 mV peak-to-peak will offset the origin of the zeros in voltage to 125 mV. As such, the signal delivered to the electromagnetic means before amplification will oscillate between −125 mV and 375 mV. Such an offset has for effect to change the origin of the vibration of the membrane 2, of the mobile portion 31 more precisely.
According to the observations of the inventor and according to the prototype tested, a positive change in the offsets makes it possible to have the device operate as discharge, while a negative change in the offsets makes it possible to have the device operate as suction.
According to an embodiment of the invention, the means generating back-and-forth movements 4 include electromagnetic means such as a magnet couple 40 associated with a coil 41. The magnet 40 can be integral with the third portion, and the coil is integral with a separate support, for example in rigid connection with the first portion 1. Other means known to those skilled in the art can also be considered, such as piezoelectric or electrostatic means.
As can be observed in
The invention also relates to a method for manufacturing a device, according to the invention, for the generating of a flow of fluid comprising the following steps:
Generally, the material used for the membrane can be an elastomer such as for example SILASTIC®, or HV 1540/20P® from Dow Corning.
A bench carried out for testing the device according to the invention is shown diagrammatically in
In such a system, the membrane 2 separates the respective volumes of the two containers R1, R2. According to the tests carried out, the volumes of the two containers R1, R2 are filled with a liquid (i.e. water), and in such a way that the device and its membrane 2 are fully immersed.
The generator of back-and-forth movements is controlled in such a way as to deform the hole of the membrane according to a mode of deformation of the hole, for example by exciting the magnet couple/coil at a given frequency (with or without voltage offset).
These tests made it possible to confirm the pertinence of the method, through the observation of a constant net flow rate through the membrane in a given direction, with this flow able to be monitored through the constant change in the difference of the level “h” of the liquid between the two containers R1, R2. During these tests, the hole (or each one of the holes) of the membrane is not associated with any added flow-regulating device such as a valve (or other element shutting off the hole in order to impose a direction of flow), nor does it have a geometry that is proper or an accessory imposing a preferred direction of circulation of fluid through the membrane.
Furthermore these tests have made it possible to demonstrate that this device operates as discharge or as suction, with the change in the direction of flow able to be obtained by changing the mode of deformation of the hole.
The net flow rates obtained during the tests were between 10 and 10,000 μL/min with water. However, higher flow rates can be considered, reasonable at least up to 900 mL/min by optimising the size and the number of openings in particular.
The simplicity and the very low cost of manufacturing the device implemented according to the invention can make it possible to design the perforated membrane and its support as a removable unit of the device, for single use.
After each use, this perforated membrane/support unit can be simply removed from the body of the device, and discarded. During a new use it is replaced with a new unused unit: this component of the device, disposable, does not need to be cleaned and/or sterilised before proceeding with another use of the device.
Naturally, other embodiments could have been considered by those skilled in the art without however leaving the scope of the invention defined by the claims hereinafter.
1. Fixed portion,
10. Recess of the fixed portion,
2. Membrane made of flexible elastomer,
20. Holes,
3. Third portion,
30. Inter-space,
31. Mobile portion,
4. Means for generating oscillations,
40. Magnet,
41. Coil,
50. O-ring,
7. Packaging,
70. Orifices,
71. Inlet,
72. Outlet.
100. Silicon,
101. Elastomer,
102. Nickel,
103. Aluminium,
104,104′. Resin.
| Number | Date | Country | Kind |
|---|---|---|---|
| 13 60387 | Oct 2013 | FR | national |
| Filing Document | Filing Date | Country | Kind |
|---|---|---|---|
| PCT/FR2014/052712 | 10/24/2014 | WO | 00 |
| Publishing Document | Publishing Date | Country | Kind |
|---|---|---|---|
| WO2015/059426 | 4/30/2015 | WO | A |
| Number | Name | Date | Kind |
|---|---|---|---|
| 5718567 | Rapp et al. | Feb 1998 | A |
| 5938117 | Ivri | Aug 1999 | A |
| 8678787 | Hirata | Mar 2014 | B2 |
| 20060232167 | Jordan | Oct 2006 | A1 |
| 20090232685 | Kamitani | Sep 2009 | A1 |
| Number | Date | Country |
|---|---|---|
| 10 2008 004147 | Jul 2009 | DE |
| 2 306 019 | Apr 2011 | EP |
| 02097270 | Dec 2002 | WO |
| Entry |
|---|
| International Search Report, dated Mar. 3, 2015, from corresponding PCT application. |
| Number | Date | Country | |
|---|---|---|---|
| 20160258430 A1 | Sep 2016 | US |
