This application is based upon and claims the benefit of priority from prior Japanese Patent Application 2007-234285 filed on Sep. 10, 2007 the entire contents of which are incorporated by reference herein.
1. Field of the Invention
The present invention relates to a method for measuring a sample in a sensor chip, a chip package for housing sensor chips, and a mechanism for fixing sensor chips.
2. Description of the Related Art
In the fields of clinical laboratory science and environmental measurement, devices capable of obtaining test results in a short time are now actively developed. Examples of such devices include sensor chips for immunochromatographic systems, dry-chemistry systems, μTAS systems, and the like.
Such sensor chip is housed in a package including: a bottom member having a depression (a pocket) formed by vacuum forming; and a film for covering the pocket. When housed in the package, the sensor chip is placed inside the pocket in a manner that a reservoir for causing reaction of a sample therein of the sensor chip faces upward. The sensor chip is then covered with the film from above. Placing the sensor chip inside the pocket in this manner makes it possible to effect the reaction of a sample in the reservoir of the sensor chip only by removing the film, with the bottom member serving as a tray for the sensor chip. The sample placed in the reservoir is caused to react for a certain period of time. Thereafter, the chip is transferred onto a measuring device for optically or electrically reading signals, so as to obtain a result of measurement.
Many measuring devices to be used for such measurement are configured to measure a single sensor chip, and the operator manually transfers the sensor chip to the measuring device. Meanwhile, there are measuring devices capable of having multiple sensor chips mounted together thereon for allowing a large number of samples to be measured in a short period of time, as disclosed in Japanese Patent Application Publication No. 2006-153642. However, even in such measuring device, the operator manually transfers sensor chips one by one onto the measuring device.
The sensor chips thus transferred are pressed by a spring against pins serving as references for positioning, and are thus fixed, for the purpose of facilitating the reading of the sample. In a case where the sensor chips are simply placed on a stage of a measuring device without precise positioning of the sensor chips, an optical system for reading signals scans over a wide range so as to read the samples.
However, the following problems arise if the operator transfers multiple sensor chips one by one onto a measuring device as disclosed in Japanese Patent Application Publication No. 2006-163642. Specifically, such transferring operation is very laborious and inefficient in any way, for example, where the operator uses a tool such as tweezers, or where the operator directly holds and transfers the sensor chips.
Moreover, in some cases, the sensor chips contain, for example, hazardous samples such as viruses, and need to be handled with care. In this case, extra attention is required particularly, for example, when the operator directly holds the sensor chips for transferring.
Meanwhile, many sensor chips, for example, many optochemical sensor chips, include bases made of glass or quartz. Consider using, for such sensors, a measuring device having a mechanism for pressing a sensor chip by a spring against a reference pin for the positioning of the sensor chip. In this case, the sensor chips may possibly be damaged, for example, a part, coming into contact with the reference pin, of the sensor chip may be cracked. Particularly, if the reference pin is made of a metal, the possibility of such damage is increased. Also consider using a measuring device in which an optical system has a mechanism for scanning sensor chips over a wide range without much precision in the positioning of the sensor chips. Such measuring device tends to have a complicated scanning mechanism as compared with measuring devices capable of highly-precise positioning.
A first aspect of the present invention is a method for measuring a sample, including fitting and mounting, onto a transfer stage, a frame-shaped chip pallet for transporting a plurality of sensor chips, the transfer stage being provided in a chip transfer block; fitting a positioning hole of a chip package having the sensor chips housed therein, on a positioning pin provided on the chip transfer block, so as to position the chip package, in a longitudinal direction, on the transfer stage; pulling, off the chip package, a bottom plate thereof which holds lower surfaces of the sensor chips, so as to simultaneously transfer the sensor chips respectively onto positions each between bars for preventing the sensor chips from moving, the bars being formed on a mounting face, onto which the sensor chips are mounted, of the transfer stage; pulling upward the chip pallet to bring the chip pallet into contact with four corners of each of the sensor chips mounted on the transfer stage, so that the sensor chips are simultaneously transferred onto the chip pallet; and mounting the chip pallet having the sensor chips mounted thereon onto a measuring device, and measuring a sample in the sensor chips.
A second aspect of the present invention is a chip package including: a housing body having a plurality of chip pockets formed at equal intervals, the chip pockets respectively housing a plurality of sensor chips each having a sample injection portion formed in an upper surface thereof the chip pockets having an opening portion exposing the sample injection portions to the outside; and a bottom plate for holding lower surfaces of the respective sensor chips. In the chip package, the bottom plate and the housing body are assembled in a manner that the bottom plate is slidable along and between folded-back portions formed in the housing.
A third aspect of the present invention is a method for measuring a sample, including: mounting a chip-discharging pallet onto a chip-fixing block of a measuring device for reading samples in a plurality of sensor chips; fitting a positioning hole of a chip package, which houses the sensor chips, onto a positioning pin provided on the chip-fixing block, so as to set, on the transfer stage, a position, in a longitudinal direction, of the chip package; pulling a bottom plate, which holds lower surfaces of the sensor chips, off the chip package, so as to simultaneously transfer the sensor chips respectively into mounting pockets formed in the chip-discharging pallet; aligning the sensor chips by displacing the positions of the sensor chips mounted in the mounting pockets by use of a displacement mechanism provided to the measuring device; fixing, by use of a fixing jig, the sensor chips aligned in the mounting pockets at the positions of the respective sensor chips; and measuring the samples in the fixed sensor chips.
A fourth aspect of the present invention is a chip-fixing device including: a chip-fixing block having guides for mounting a plurality of sensor chips; a displacement mechanism for displacing the positions of the respective sensor chips by moving the chip-fixing block; and a fixing jig for fixing the positions of the sensor chips displaced on the chip-fixing block. The displacement mechanism includes: a cam mechanism including a first cam and a second cam, the first cam moving a first follower in one direction, the second cam being connected to the first follower and moving a second follower in a direction orthogonal to the direction in which the first follower moves, the second follower being connected to the chip-fixing block; and a first linear guide bearing being connected to the second follower, and moving the chip-fixing block in a direction not orthogonal to the direction in which the second follower moves. The fixing jig includes: a third follower moved by the first cam in the same direction as that in which the first follower moves; a third cam connected to the third follower; a fourth follower moved by the third cam in the same direction as that in which the third follower; a second linear guide bearing allowing the fourth follower to move in a direction orthogonal to the sensor chips mounted on the chip-fixing block; and chip-fixing pins connected to the fourth follower in an orthogonal direction, and are brought respectively into contact with the sensor chips so as to fix the sensor chips.
Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
A chip package 1 for housing sensor chips according to an embodiment of the present invention has an appearance as shown in a plan view of
The housing body 2 has pockets 2b for housing the sensor chips SC. Each of the sensor chips SC housed in the pockets 2b has a sample injection portion formed at the center of an upper portion of a reservoir having the shape of rectangular parallelepiped. For this reason, each of the sensor chips SC has a convex cross-sectional shape. Each of the pockets 2b has a rectangular shape slightly larger than the outer dimensions of each sensor chip SC, so that the sensor chip SC is allowed to be housed in the pocket 2b. Employing the pockets 2b each having such a size prevents the sensor chip SC in the pocket 2b from being shifted to a large extent. In addition, each of the pockets 2b is formed into a shape protruding from the surface of the housing body 2 to a aide opposite to the folded-back portions 2a, in order to house the sensor chip SC having the above-described shape.
The bottom plate 3 is fitted into the folded-back portions 2a and 2a, thus serving as the bottom plate of the chip package 1, so that a space in which the sensor chips SC are housed is formed by the housing body 2 and the bottom plate 3. Then, each sensor chip SC is housed in the corresponding pocket 2b formed in the housing body 2 while the lower surface of the sensor chip SC is held by the bottom plate 3.
Multiple pockets 2b are formed in the housing body 2. Moreover, each of the pockets 2b is formed so as to allow the sensor chip SC to be housed therein in a manner that the longitudinal side of the sensor chip SC intersects, at night angles, the longitudinal side of the housing body 2. The formation of the pockets 2b in the above-described manner makes it possible to house the multiple sensor chips SC in the pockets 2b in a manner that the sample injection portions of the respective sensor chips SC are aligned in a line.
Moreover, each adjacent two of the multiple pockets 2b are divided by a partition wall 2c. These partition walls 2c makes it possible to individually house the sensor chips SC respectively in the pockets 2b, instead of collectively housing the multiple sensor chips SC. In addition, the provision of the partition walls 2c defies a mounting position of each sensor chip SC at the time when the sensor chips SC are transferred to a chip transfer block or a chip pallet, which will be described later. Each of the partition walls 2c lie in the same plane as the surface of the housing body 2, but does not have a shape protruding from the housing body 2 as in the case of the pockets 2b. The partition wall 2c with this shape divides each adjacent two of the pockets 2b from each other.
Although eight pockets 2b are provided while being divided from one another by seven partition walls 2c in the embodiment of the present invention, it may be freely set in consideration of the shape and the like of each sensor chip SC how many pockets 2b are provided in the housing body 2.
An opening portion 2d is formed in the pockets 2b by cutting off parts, at which the sample injection portions of the sensor chips SC are positioned, of the pockets 2b. Through this opening portion 2d, the pockets 2b, formed between the housing body 2 and the bottom plate 3 are opened partially at the positions of the sample injection portions of the respective sensor chips SC housed in the pocket 2b. The opening portion 2d thus formed in this manner makes it possible to perform examination by injecting a sample into the sample injection portion without removing, from the chip package 1, the sensor chips SC housed in the chip package 1.
Before the start of examination, the chip package 1 is handled in a state where the sensor chips SC are housed in the chip package 1. In this state, the opening portion 2d is closed up by a seal or the like attached to the part of the opening portion 2d. In the embodiment of the present invention, the opening portion 2d is formed, as shown in
A positioning hole 2e is formed in the surface of the housing body 2. In the embodiment of the present invention, the positioning hole 2e is formed, as shown in
Specifically, a positioning pin 34 provided on the chip transfer block 31 is inserted through the positioning hole 2e from the bottom plate 3 side. The position, in the longitudinal direction, of the chip package 1 can thereby be determined with respect to the chip transfer block 31. Note that, although the positioning hole 2e is formed, as described above, at the position shown in
Second protruding portions 3c and 3c are formed on the two edges of the other end portion, in the longitudinal direction, of the bottom plate 3. These second protruding portions 3c and 3c have a function of preventing the bottom plate 3 from falling off the housing body 2 in the same manner as that of the first protruding portions 3b and 3b. On the other hand, the second protruding portions 3c and 3c are required to be able to be easily removed when the bottom plate 3 is removed in a sliding manner from the housing body 2 with the gripper 3a being gripped. For this reason, the protruding amount of each of the second protruding portions 3c and 3c from the longer side of the bottom plate 3 is smaller than the first protruding portions 3b and 3b. In addition, the shape of each of the second protruding portions 3c and 3c is formed to have a curved section.
A cutout 3d having an elongated rectangular shape is formed in the other end portion, in the longitudinal direction, of the bottom plate 3. A dead end portion 3e of the cutout 3d is formed so that the position of the dead end portion 3e matches a part of the positioning hole 2e formed in the surface of the housing body 2 when the housing body 2 and the bottom plate 3 are assembled as shown in
When the sensor chips SC housed in the chip package 1 are transferred to the chip transfer block 31, the positioning pin 34 of the chip transfer block 31 is inserted, as described above, from the bottom plate 3 side into the positioning hole 2e of the housing body 2 (at this time, the positioning pin 34 is brought into contact with the dead end portion 3e of the cutout 3d). Then, after the chip package 1 is positioned on the chip transfer block 31, the sensor chips SC are transferred. The cutout 3d is formed in order to avoid the interference of the positioning pin 34 with the bottom plate 3, which would otherwise prevent the bottom plate 3 from being pulled out of the housing body 2. The cutout 3d thus formed allows the positioning pin 34 to pass therethrough when the bottom plate 3 is pulled out of the housing body 2.
When the bottom plate 3 is pulled in a direction indicated by the arrow shown in
Next, the chip pallet 11 is used for transferring, to another place, the sensor chips SC having transferred onto the chip transfer block 31. As shown in
The chip pallet 11 is formed of a pair of lateral frames 12 and 12 extending in parallel with each other; and a pair of vertical frames 13 and 13 extending in parallel with each other and connecting end portions of the lateral frames 12 and 12 on each side. Multiple positioning ribs 14 are formed at equal intervals on each of inside edge portions 12a and 12a, facing each other, of the respective lateral frames 12 and 12. In the chip pallet 11 according to the embodiment of the present invention, nine positioning ribs 14 are formed on each of the inside edge portions 12a and 12a, so that eight sensor chips SC can be mounted on the chip pallet 11.
Each of the positioning ribs 14 is formed of a first rib 14a which defines the arrangement positions of the sensor chips SC to be mounted on the chip pallet 11; and second ribs 14b onto which the sensor chip SC is transferred. Each of the first ribs 14a has the shape of a substantially rectangular parallelepiped. The sensor chip SC is placed between each two first ribs 14a and 14a adjacent to each other. Each of the second ribs 14b is provided in a substantially triangular shape as connecting the first rib 14a and the inside edge portion 12a. The sensor chip SC is mounted on the chip pallet 11 in a way that the four corners of the sensor chip SC is placed on the second ribs 14b, each two of which are provided between the adjacent two first ribs 14a and 14a on each side. In addition, since the second ribs 14b are formed to have a height lower than that of the first ribs 14a, the position at which each sensor chip SC is mounted on the chip pallet 11 is determined by the positioning ribs 14 and the inside edge portions 12a.
Holes 15 and 15 are formed in intermediate portions respectively of the pair of vertical frames 13 and 13. The positioning pin 34 provided on and protruding from the chip transfer block 31 is inserted through one of the holes 15 and 15. In addition, transport rods 16 for transporting the chip pallet 11 are provided respectively on parts each connecting the lateral frame 12 and the vertical frame 13. In the chip pallet 11, a pair of the transport rods 16 are provided at positions opposite to each other.
The transfer stage 33 is provided on the base 32, and the sensor chips SC housed in the chip package 1 are transferred onto the transfer stage 33. Then, the sensor chips SC are transferred from the transfer stage 33 onto the chip pallet 11. The transfer stage 33 is formed, on the base 32, so as to have a certain thickness in the Z-axis direction shown in
Faces 33a and bars 33b are formed on a surface, opposite to the surface connected to the base 32, of the transfer stage 33. The sensor chips SC transferred from the chip package 1 are mounted on the faces 33a (hereinafter, referred to as “mounting faces”). The bars 33b are formed each between adjacent two of the mounting faces 33a.
The bars 33b are formed to have a height, in the Z-axis direction, greater than that of the mounting faces 33a. In addition, the bars 33b extend in a direction parallel to the longitudinal direction (the Y-axis direction in
The length, in the Y-axis direction, of each mounting face 33a is shorter than the length, in the longitudinal direction, of each sensor chip SC. For this reason, end portions, in the longitudinal direction, of each sensor chip SC protrude from the mounting face 33a. The mounting faces 33a have such structure for the following reason. If the mounting faces 33a were formed so that the entire region of the lower surface of the sensor chip SC is mounted on the mounting face 33a, the sensor chips SC could not be transferred to the chip pallet 11 by use of the chip transfer block 31.
Convex portions 33c are formed on surfaces of the transfer stage 33, which are orthogonal to the mounting faces 33a and also orthogonal to the longitudinal direction of the sensor chips SC. Specifically, each convex portion 33c is formed to protrude to the outer side of the transfer stage 33, in a region directly below one of the two end portions of the sensor chip SC, between the mounting face 33a and the base 32. In the embodiment of the present invention shown in
In the embodiment of the present invention, each convex portion 33c has, as shown in
The positioning pin 34 is provided on a portion in the vicinity of the center of one end portion, in the longitudinal direction (the X-axis direction) of the transfer stage 33. The positioning pin 34 is used for positioning the chip package 1 when the sensor chips SC are to be transferred onto the transfer stage 33. The position, in the longitudinal direction, of the chip package 1 is set on the transfer stage 33 in a way that the positioning pin 34 is inserted through the cutout 3d of the bottom plate 3 and through the positioning hole 2e of the housing body 2.
In addition, the positioning guides 85 aligned with the Y-axis direction of the transfer stage 33 are formed on portions in the vicinity of the other end portion, in the longitudinal direction, of the transfer stage 33. These positioning guides 35 are used for positioning the chip package 1 in the direction along the shorter sides of the chip package 1. These positioning guides 35 are formed on portions in the vicinity of the other end portion, in the longitudinal direction of the transfer stage 33 in the embodiment of the present invention. However, these positioning guides 35 may be formed on any portions, in the longitudinal direction, of the transfer stage 33 as long as these positioning guides 35 allow the chip package 1 to be positioned in the direction along the shorter sides of the chip package 1. Moreover, although formed at positions opposite to each other in
Next, a part of a method for measuring a sample housed in the sensor chips SC will be described. The part to be described here is a procedure that the sensor chips SC are transferred onto the chip pallet 1 after the sensor chips SC housed in the chip package 1 are once transferred onto the chip transfer block 31.
As shown in
In this state, the two edges of the chip package 1 in the direction along the shorter sides thereof, are sandwiched by the pair of positioning guides 35 formed on the chip transfer block 31. The position of the chip package 1 is thus set on the transfer stage 33. In addition, in this state, the bottom plate 3 of the chip package 1 is placed on the bars 33b of the transfer stage 33. In the state where the chip package 1 is placed at such position on the transfer stage 33, the sensor chips SC housed in the chip package 1 are located respectively above the mounting faces 33a.
Now, pulling the gripper 3a of the bottom plate 3 in the chip package 1 in a direction indicated by the arrow shown in
In this state, the chip pallet 11 having been fitted onto the chip transfer block 31 is pulled up.
Then, the chip pallet 11 having the multiple sensor chips SC mounted thereon is placed on the unillustrated measuring device, and the sample in the sensor chips SC is measured.
Using the chip package 1, the chip pallet 11, and the chip transfer block 31, which have been described so far, makes it possible to provide a method for measuring a sample, a chip package for sensor chips, and a mechanism for fixing sensor chips, all of which enable the operator to easily, promptly, and also safely, transfer multiple sensor chips onto a measuring device indirectly, or without using any tool, and to fix the sensor chips with a simple structure, when transferring the sensor chips onto the measuring device in order to measure samples in the sensor chips.
Next, a second embodiment of the present invention will be described. Note that, in the second embodiment, the same constituent elements as those described in the above first embodiment are denoted by the same reference numerals, and the overlapping description thereof will be omitted.
The second embodiment shows procedures of transferring, mounting, and then fixing sensor chips onto a measuring device in the method of measuring samples.
A fixing device 40 includes a chip-fixing block 50, a displacement mechanism 60, and a fixing jig 80. Sensor chips SC are mounted on the chip-fixing block 50. The displacement mechanism 60 is configured to move the chip-fixing block 50, thereby displacing the sensor chips SC to positions where the sensor chips SC are to be fixed, respectively. The fixing jig 80 fixes the position of the sensor chips SC displaced on the chip-fixing block 50. All of the chip-fixing block 50, the displacement mechanism 60, and the fixing jig 80 are provided to a measuring device R, which is not illustrated in
The sensor chips SC are mounted on the chip-fixing block 50, and fixed thereto by the fixing jig 80. Then, the samples contained in the insides of the sensor chips SC are read by a reading device (a scanning mechanism) provided to the measuring device R.
In the chip-fixing block 50, guides 51 for mounting the sensor chips SC are formed. Each of the guides 51 is formed to be capable of three sides, including a shorter side, of the sensor chip SC. In addition, each pair of guides 51 and 51 are formed at such positions that parts, each of which holds the shorter side, of the respective guides 51 and 51 face each other. Each pair of these guides 51 and 51 hold one sensor chip SC. Multiple pairs of guides 51 and 51 (eight pairs in the embodiment of the present invention) are formed along the longitudinal direction indicated by the Y-axis direction in
Moreover, the chip-fixing block 50 is provided with positioning pins 53 for positioning the chip-discharging pallet 52 to be mounted on the chip-fixing block 50. In the embodiment of the present invention, a pair of the positioning pins 53 are provided, each at the center in the width direction (the X-axis direction) of the chip-fixing block 50, in the manner of sandwiching the multiple guides 51.
The chip-discharging pallet 52 is a pallet for discharging the sensor chips SC from the measuring device R after the sensor chips SC are mounted on the chip-fixing block 50 and then the samples are read by the measuring device R.
Mounting pockets 52b for housing the sensor chips SC are formed in the chip-discharging pallet 62 in a manner that the mounting pockets 52b are sandwiched by the positioning holes 52a and 52a. In the embodiment of the present invention, eight mounting pockets 52b are formed. In addition, a pair of mounting pieces 52c and 52c are formed respectively on two sides, facing each other in the X-axis direction, of each of the mounting pockets 52b. When the sensor chips SC housed respectively in the mounting pockets 52b mounted on the guides 51 are discharged, the lower surface of each of the sensor chips SC is brought into contact with the mounting pieces 52c and 52c. Accordingly, when the chip-discharging pallet 52 is pulled off the chip-firing block 50, the sensor chips SC are also pulled off the chip-fixing block 50 at the same time.
As shown in
The displacement mechanism 60 includes, as shown in
The first cam 62 is a translate cam as shown in
The first follower 61 has the cam follower 61a and the second cam 64. The cam follower 61a is provide to one end portion of the first follower 61, the one end portion being in contact with the first cam 62. The second cam 64 is formed on the other end portion of the first follower 61. The cam follower 61a is designed to be capable of moving on the first cam 62. The second cam 64 is a cam for moving the second follower 63, and is formed in a substantially trapezoidal shape which has a slop inclined downward while extending toward the chip-fixing block 50 in the X-axis direction Having such shape, the second cam 64 is capable of moving the second follower 63 to the right in the X-axis direction shown in
What is moved by the second cam 64 is the second follower 63. One end portion of the second follower 63 has the cam follower 63a attached thereto. The other end portion of the second follower 63 is formed into a free end which is allowed to freely move in the X-axis direction.
The second follower 63 is provided in the manner of penetrating the chip-fixing block 50 in the X-axis direction, and is connected to the first linear guide bearings L1 and L1 respectively at two positions below the second follower 63 in the Z-axis direction. The second follower 63 and each first linear bearing L1 are coupled to each other by a pin. This pin is also connected to the chip-fixing block 50, and further, is utilized as the positioning pin 53 for positioning the chip-discharging pallet 52 on the chip-fixing block 50.
Each of the first linear guide bearings L1 includes a rail member L1a and a bearing member L1b which moves on and along the rail member L1a. Each first linear guide bearing L1 is fixed to the measuring device R so as to extend in a direction which is not orthogonal to the second follower 63 (a non-orthogonal direction). In addition, an urging member L1c is connected to each bearing member L1b.
Hereinafter, description will be given of how the chip-fixing block 60 is moved by the cam mechanism C and the first linear guide bearings L1 and L1 all included in the displacement mechanism 60. Specifically, moving the first cam 62 in the X-axis direction (the direction indicated by the solid arrow A1) causes the cam follower 61a to run onto the first bump 62a. When the cam follower 61a runs on the first bump 62a, the first follower 61 moves in the Y-axis direction (the direction indicated by the solid arrow A2) in the manner of pushing upward the second cam 64. Since the second cam 64 has such shape as described above, the second follower 63 is caused to move in the X-direction (the direction indicated by the solid arrow A3) in conjunction with the cam follower 63a by the second cam 64. Although the second follower 63 and the first cam 62 move respectively in the directions indicated by the arrows A1 and A3, that is, both in the X-axis direction, the directions of the movements thereof are opposite to each other.
When the second follower 63 moves in the direction of the arrow A3, the bearing member L1b of each first linear guide bearing L1 connected to the second follower 63 moves along the rail member L1a in the direction indicated by the arrow A4. In this event, the urging member L1c connected to the bearing member L1b extends in association with the movement of the bearing member Lib. The movement in the direction of the arrow A3 and the movement in the direction of the arrow A4 cause the chip-fixing block 50 to move in the direction indicated by the arrow A5.
When the first cam 62 further moves in the direction of the arrow A1, the cam follower 61a runs down from the first bump 62a. The first follower 61 then moves in the direction indicated by the dashed arrow B2, while the second follower 63 moves in the direction indicated by the dashed arrow B3. Moreover, in association with this movement of the second follower 63, the urging member L1c return to its original state, so that the bearing member Lib moves in the direction indicated by the dashed arrow B4. Accordingly, the chip fig block 50 moves in the direction indicated by the dashed arrow B5, and the first cam 62 returns to the state before the movements.
The fixing jig 80 includes, as shown in
Although not shown in
In addition, the fourth follower 85 having the cam follower 84 attached to the one end thereof is connected further to the second linear bearing L2. The second linear guide bearing L2 includes a rail member L2a and a bearing member L2b which moves on along the rail member L2a. Connected to the second linear guide bearing L2, the fourth follower 85 is capable of moving in the Z-axis direction.
As shown in
Specifically, as indicated by the arrow C1 in
The cam follower 81 (the third follower 82) also runs onto the second bump 62b at the same time when the cam follower 61a (the first follower 61) runs onto the first bump 62a. Such movement of the cam follower 81 pushes the first jig 80 from the position shown in
As shown in
When the sensor chips SC are transferred from the chip package 1, the positions of the sensor chips SC in the mounting pockets 52b are not aligned. The above-described operation of the displacement mechanism 60 eventually causes each of the sensor chips SC to come into contact with a specific corner (the second corner 52bb in the embodiment of the present invention) of the mounting pocket 52b, and also to be fixed by the fixing jig 80.
Using the chip package 1, the chip-fixing block 50, the chip-discharging pallet 52, the displacement mechanism 60, and the fixing jig 80, which have been described so f makes it possible to provide a method for measuring a sample, a chip package for sensor chips, and a mechanism for fixing sensor chips, all of which enable the operator to easily, promptly, and also safely, transfer multiple sensor chips onto a measuring device indirectly, or without using any tool, and to fix the sensor chips with a simple structure, when transferring the sensor chips onto the measuring device in order to measure samples in the sensor chips.
It should be noted that, the present invention is not limited to the above-described embodiments as they are, and may be embodied, when to be implemented, with modification made on the constituent elements without departing from the scope of the present invention. Moreover, a variety of inventions may be formed by combining, as appropriate, multiple constituent elements out of those disclosed in A the above-described embodiments. For example, some constituent elements may be omitted from among all the constituent elements shown in the embodiments. Furthermore, constituent elements of the different embodiments may be appropriately combined as appropriate.
Number | Date | Country | Kind |
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P2007-234285 | Sep 2007 | JP | national |