Claims
- 1. A method of purification of physiological liquids of organism, comprising the steps of removing a physiological liquid with toxicant from a patient; passing the physiological liquid with the toxicants through a material which has a size, a shape, and a structure providing removal of toxic compounds in the molecular range of 300 to 30000 Dalton from the physiological liquid and which is composed of a porous hydrophobic divinylbenzene copolymer, which initially has surface exposed vinyl groups in which thereafter the vinyl groups are chemically modified and form different surface exposed functional groups, which are hydrophilic and biocompatible; and returning the liquid to the patient.
- 2. A method as defined in claim 1, wherein said porous hydrophobic divinylbenzene copolymer comprises a copolymer of divinylbenzene with comonomers selected from the group consisting of styrene, ethylstyrene, acrylo nitrile, and buthyl methacrylate.
- 3. A method as defined in claim 1, wherein said surface exposed functional groups which are hydrophilic and biocompatible are grafted hydrophilic polymeric chains selected from a group consisting of polymers of 2-hydroxyethyl methacrylate, N-vinylpyrrolidone, N-vinylcaprolactame, and N-acrylamide.
- 4. A method as defined in claim 1, wherein said surface exposed functional groups which are hydrophilic and biocompatible are products of oxidation of said vinyl groups to epoxy groups and subsequent addition of polar compounds selected from a group which includes water, ethylene glycole, small primary or secondary amines, 2-hydroxyethyl-amine.
- 5. A method as defined in claim 3, wherein said surface exposed functional groups which are hydrophilic and biocompatible are products of oxidation of said vinyl groups to epoxy groups and subsequent addition of small primary or secondary amines or 2-hydroxyethyl-amine and depositing high-molecular-weight poly(trifluoroethoxy) phosphazene.
CROSS-REFERENCE TO A RELATED APPLICATION
This application is a division of application Ser. No. 09/019,583 filed on Feb. 6, 1998 allowed.
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Divisions (1)
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Number |
Date |
Country |
Parent |
019583 |
Feb 1998 |
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