Claims
- 1. A support for binding low density lipoprotein cholesterol comprising a microporous polysulfone structure having pore diameters in the range from about 0.1 microns to about 0.7 microns and having an amount of polyacrylic acid effective to bind low density lipoprotein cholesterol immobilized by an interpenetrating network on the surface of said polysulfone structure.
- 2. The support of claim 1 wherein said structure is a flat sheet membrane.
- 3. The support of claim 1 wherein said structure is a bead.
- 4. A support for binding low density lipoprotein cholesterol comprising a microporous polysulfone structure having pore diameters in the range of from about 0.1 microns to about 0.7 microns and having polyacrylic acid and a calcium ion containing compound immobilized by an interpenetrating network on the surface of said polysulfone structure, wherein the amount of polyacrylic acid is effective to bind low density lipoprotein cholesterol and the calcium ion containing compound is in an amount effective to enhance the quantity of polyacrylic acid immobilized on the structure.
- 5. A support for binding low density lipoprotein cholesterol comprising a microporous polysulfone structure having pore diameters in the range of from about 0.1 microns to about 0.7 microns and having polyacrylic acid, a calcium ion containing compound and silica immobilized by an interpenetrating network on the surface of said polysulfone structure, wherein the amount of polyacrylic acid is effective to bind low density lipoprotein cholesterol and the calcium ion containing compound and silica are in an amount effective to enhance the quantity of polyacrylic acid immobilized on the structure.
- 6. The support of claim 1, wherein said pore diameter ranges from about 0.4 microns to about 0.65 microns.
- 7. The support of claim 4, wherein said pore diameter ranges from about 0.4 microns to about 0.65 microns.
- 8. The support of claim 5, wherein said pore diameter ranges from about 0.4 microns to about 0.65 microns.
Parent Case Info
This is a continuation of application Ser. No. 07/882,985 filed May 14, 1992, now abandoned, which is a continuation-in-part of U.S. Ser. No. 618,791, filed Nov. 27, 1990, now U.S. Pat. No. 5,187,010.
US Referenced Citations (5)
Foreign Referenced Citations (4)
Number |
Date |
Country |
1163574 |
Mar 1984 |
CAX |
0087807 |
May 1985 |
JPX |
1212305 |
Sep 1986 |
JPX |
63-232845 |
Sep 1988 |
JPX |
Non-Patent Literature Citations (2)
Entry |
Thies et al., Artificial Organs, 12, 320, 1988. |
Naito, Artificial Organs, 13, 190, 1989. |
Continuations (1)
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Number |
Date |
Country |
Parent |
882985 |
May 1992 |
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Continuation in Parts (1)
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Number |
Date |
Country |
Parent |
618791 |
Nov 1990 |
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