Claims
- 1. An isolated nucleic acid fragment that encodes the protein of SEQ ID NO:2.
- 2. The nucleic acid fragment of claim 1 having the sequence of SEQ ID. NO:1.
- 3. The nucleic acid fragment of claim 2 wherein T is U.
- 4. A nucleic acid fragment that is the complement of SEQ ID:1, or a fragment thereof at least 17 bases in length that will selectively hybridize to DNA which encodes the protein of SEQ ID NO:2.
- 5. A recombinant expression vector including the nucleic acid fragment of claim 1.
- 6. A recombinant expression vector including the nucleic acid fragment of claim 2 or 4.
- 7. The vector of claim 6, wherein the vector is a plasmid.
- 8. A host cell stably transformed with the vector of claim 7.
- 9. The host cell of claim 8, wherein the cell is eukaryotic.
- 10. The host cell of claim 8, wherein the cell is prokaryotic.
- 11. A method for preparing an isolated rare outer membrane protein of T. pallidum which comprises culturing the host cell of claim 8, 9 or 10, and recovering a rare outer membrane protein of T. pallidum.
Parent Case Info
This is a divisional of application Ser. No. 08/292,904, filed Aug. 17, 1994, now abandoned, which is a continuation in part of Ser. No. 08/255,322, filed Jun. 7, 1994, now abandoned, which is a continuation in part of Ser. No. 08/178,084, filed Jan. 6, 1994, now abandoned.
Government Interests
This work was supported by U.S. Government NIH grant AI 21352 and AI 29733.
Non-Patent Literature Citations (2)
Entry |
Norris et al, Microbiological Reviews (1993) 57:750-779. |
Blanco et al, 1991, Molecular Microbiology 5(10) 2405-2415. |
Divisions (1)
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Number |
Date |
Country |
Parent |
292904 |
Aug 1994 |
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Continuation in Parts (2)
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Number |
Date |
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255322 |
Jun 1994 |
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Parent |
178084 |
Jan 1994 |
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