Claims
- 1. A self-reinforced polymeric material comprising (a) a monofunctional acrylate or methacrylate monomer of formula (1), (b) a difunctional acrylate or methacrylate cross-linking monomer, and (c) a cross-linked acrylate or methacrylate microsphere of formula (2): wherein:A=H, CH3, CH2CH3, CH2OH; B=(CH2)m or [O(CH2)2]n; D=(CH2)w; m=2-6; n=1-10; Y is nothing, O, S, or NR, provided that if Y is O, S, or NR, then B is (CH2)m; R is H, CH3, CnH2n+1 (n=1-10), iso-OC3H7, C6H5, or CH2C6H5; w=0-6, provided that m+w≦8; and E is H, C1-C4 alkyl, C1-C4 alkoxy, C6H5, CH2C6H5, or F, Cl, Br.
- 2. The polymeric material of claim 1 wherein the material is made by radical polymerization of the monofunctional acrylate or methacrylate monomer of formula (1) and the difunctional acrylate or methacrylate cross-linking monomer in the presence of the cross-linked acrylate, or methacrylate microsphere of formula (2).
- 3. The polymeric material of claim 1 wherein the difunctional acrylate or methacrylate cross-linking monomer (b) is selected from the group consisting of ethylene glycol dimethacrylate; diethylene glycol dimethacrylate; allyl methacrylate; 1,3-propanediol dimethacrylate; 2,3-propanediol dimethacrylate; 1,6-hexanediol dimethacrylate; 1,4-butanediol dimethacrylate; CH2═C(CH3)C(O)O(CH2CH2O)n—C(O)C(CH3)═CH2 where n=1-50; CH2═C(CH3)C(O)O(CH2)tO—C(O)C(CH3)═CH2 where t=3-20; and their corresponding acrylates.
- 4. The polymeric material of claim 1 wherein the polymeric material comprises 75-98% (w/w) of the monofunctional acrylate or methacrylate monomer of formula (1), 0.1-5% (w/w) of the difunctional acrylate of methacrylate cross-linking monomer, and 1-20% (w/w) of the cross-linked acrylate or methacrylate microsphere of formula (2).
- 5. The polymeric material of claim 4 wherein the polymeric material comprises 1-5% (w/w) of the cross-linked acrylate or methacrylate microsphere of formula (2).
- 6. The polymeric material of claim 1 wherein the material further comprises an ingredient selected from the group consisting of reactive UV absorbers and reactive blue-light absorbers.
- 7. An ophthalmic or otorhinolaryngological device selected from the group consisting of intraocular lenses; contact lenses; keratoprostheses; corneal rings or inlays; otological ventilation tubes; and nasal implants, wherein the device comprises a self-reinforced polymeric material comprising (a) a monofunctional acrylate or methacrylate monomer of formula (1), (b) a difunctional acrylate or methacrylate cross-linking monomer, and (c) a cross-linked acrylate or methacrylate microsphere of formula (2): wherein:A=H, CH3, CH2CH3, CH2OH; B=(CH2)m or [O(CH2)2]n; D=(CH2)w; m=2-6; n=1-10; Y is nothing, O, S, or NR, provided that if Y is O, S, or NR, then B is (CH2)m; R is H, CH3, CnH2n+1 (n=1-10), iso-OC3H7, C6H5, or CH2C6H5; w=0-6, provided that m+w≦8; and E is H, C1-C4 alkyl, C1-C4 alkoxy, C6H5, CH2C6H5, or F, Cl, Br.
- 8. The ophthalmic or otorhinolaryngological device of claim 7 wherein the self-reinforced polymeric material is made by radical polymerization of the monofunctional acrylate or methacrylate monomer of formula (1) and the difunctonal acrylate or methacrylate cross-linking monomer in the presence of the cross-linked acrylate, or methacrylate microsphere of formula (2).
- 9. The ophthalmic or otorhinolaryngological device of claim 7 wherein the difunctional acrylate or methacrylate cross-linking monomer (b) is selected from the group consisting of ethylene glycol dimethacrylate; diethylene glycol dimethacrylate; allyl methacrylate; 1,3-propanediol dimethacrylate; 2,3-propanediol dimethacrylate; 1,6-hexanediol dimethacrylate; 1,4-butanediol dimethacrylate; CH2═C(CH3)C(O)O(CH2CH2O)n—C(O)C(CH3)═CH2 where n=1-50; CH2═C(CH3)C(O)O(CH2)tO—C(O)C(CH3)═CH2 where t=3-20; and their corresponding acrylates.
- 10. The ophthalmic or otorhinolaryngological device of claim 7 wherein the self-reinforced polymeric material comprises 75-98% (w/w) of the monofunctional acrylate or methacrylate monomer of formula (1), 0.1-5% (w/w) of the difunctional acrylate of methacrylate cross-linking monomer, and 1-20% (w/w) of the cross-linked acrylate or methacrylate microsphere of formula (2).
- 11. The ophthalmic or otorhinolaryngological device of claim 10 wherein the self-reinforced polymeric material comprises 1-5% (w/w) of the cross-linked acrylate or methacrylate microsphere of formula (2).
- 12. The ophthalmic or otorhinolaryngological device of claim 11 wherein the self-reinforced polymeric material further comprises an ingredient selected from the group consisting of reactive UV absorbers and reactive blue-light absorbers.
- 13. The ophthalmic or otorhinolaryngological device of claim 7 wherein the self-reinforced polymeric material comprises 65-70% (w/w) of 2-phenylethyl acrylate, 25-33% (w/w) of 2-phenylethyl methacrylate, 1-4% (w/w) of cross-linked 2-phenylethyl methacrylate microspheres having an average diameter 0.1-1 μm, and 0.5-1.5% (w/w) of a difunctional acrylate or methacrylate cross-linking monomer.
Parent Case Info
This application claims priority to U.S. Provisional Application, U.S. Ser. No. 60/396,201 filed Jul. 16, 2002.
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Number |
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|
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