Claims
- 1. A packing material for solid phase extraction comprising a synthetic polymer comprising a hydrophobic group and an ion exchange group.
- 2. A packing material for solid phase extraction, comprising a synthetic polymer obtained by copolymerizing a hydrophobic monomer (A) and a hydrophilic monomer (B) and introducing thereto an ion exchange group by a chemical modification.
- 3. The packing material for solid phase extraction as claimed in claim 1, which contains an aromatic divinyl compound as the hydrophobic monomer (A) in an amount of 30% by mass or more based on a total amount of monomers.
- 4. The packing material for solid phase extraction as claimed in claim 1 or 2, which contains an N-vinylcarboxylic acid amide as the hydrophilic monomer (B) in an amount of 5 to 60% by mass based on the total amount of monomers.
- 5. The packing material for solid phase extraction as claimed in claim 4, wherein the N-vinylcarboxylic acid amide is N-vinyl-2-pyrrolidone or N- vinylacetamide.
- 6. The packing material for solid phase extraction as claimed in claim 1 or 2, which contains a (meth)acrylic acid ester of a polyhydric alcohol having a hydroxyl group as the hydrophilic monomer (B) in an amount of 10% by mass or more based on a total amount of monomers.
- 7. The packing material for solid phase extraction as claimed in claim 6, wherein the (meth)acrylic acid ester of a polyhydric alcohol having a hydroxyl group is glycerol dimethacrylate.
- 8. The packing material for solid phase extraction as claimed in claim 1 or 2, wherein the ion exchange group is covalently bonded to the polymer.
- 9. The packing material for solid phase extraction as claimed in claim 1 or 2, wherein the ion exchange group covalently bonded is a sulfo group or a quaternary ammonium.
- 10. The packing material for solid phase extraction as claimed in claim 1 or 2, wherein an amount of an ion-exchange group covalently bonded is 5-equivalent or more based on 1 dry gram of the packing material.
- 11. The packing material for solid phase extraction as claimed in claim 1 or 2, which packs a packing apparatus.
- 12. The packing material for solid phase extraction as claimed in claim 11, wherein the packing apparatus is a column, a cartridge or a reservoir.
- 13. The packing material for solid phase extraction as claimed in claim 1 or 2, which is used for concentrating an objective component and/or removing impurities or contaminants.
- 14. The packing material for solid phase extraction as claimed in claim 1 or 2, which has an average particle size of 1 to 200 μm.
- 15. A method comprising carrying out a solid phase extraction employing a column switching method and the packing material for solid phase extraction described in claim 1 or 2.
- 16. A column for solid phase extraction, comprising a column packed with the packing material for solid phase extraction described in claim 1 or 2.
- 17. A cartridge for solid phase extraction, comprising a cartridge packed with the packing material for solid phase extraction described in claim 1 or 2.
- 18. The column for solid phase extraction as claimed in claim 16, which concentrates, identifies or quantifies an objective component and/or removes impurities or contaminants.
- 19. The cartridge for solid phase extraction as claimed in claim 17, which concentrates, identifies or quantifies an objective component and/or removes impurities or contaminants.
- 20. A solid phase extraction method for an environment-related, medical or biological sample, comprising concentrating, identifying or quantifying an objective component and/or removing impurities with the column for solid phase extraction described in claim 16.
- 21. A solid phase extraction method for an environment-related, medical or biological sample, comprising concentrating, identifying or quantifying an objective component and/or removing impurities with the column for solid phase extraction described in claim 17.
- 22. The method as claimed in claim 20, wherein a drug sample in serum is identified or quantified.
- 23. The method as claimed in claim 21, wherein a drug sample in serum is identified or quantified.
Priority Claims (1)
Number |
Date |
Country |
Kind |
P2000-165473 |
Jun 2000 |
JP |
|
CROSS REFERENCE TO RELATED APPLICATIONS
[0001] This application is an application filed under 35 U.S.C. §111(a) claiming benefit pursuant to 35 U.S.C. §119(e)(1) of the filing date of Provisional application Ser. No. 60/279,108 filed Mar. 28, 2001 pursuant to 35 U.S.C. §111(b).
Provisional Applications (1)
|
Number |
Date |
Country |
|
60279108 |
Mar 2001 |
US |