Claims
- 1. The compound of formula I ##STR45## wherein R.sub.1 and R.sub.2 are methyl, R.sub.3 is para-methoxyphenyl
- R.sub.4 is carboxy,
- each R.sub.5 is hydrogen,
- X is oxygen,
- Y is a direct bond, and the carbon atom in the 10 position has the D-configuration.
- 2. A pharmaceutical composition comprising a therapeutically effective amount of the compound according to claim 1 and a pharmaceutically acceptable carrier therefor.
- 3. A method of treating fungus infections in a subject in need of said treatment, which comprises administering to said subject an anti-fungal effective amount of the compound according to claim 1.
- 4. The compound of formula I ##STR46## wherein R.sub.1 and R.sub.2 are methyl, R.sub.3 is para-methoxyphenyl,
- R.sub.4 is tert-butoxycarbonyl,
- each R.sub.5 is hydrogen,
- X is oxygen,
- Y is a direct bond,
- and the carbon atom in the 10 position has the L-configuration.
- 5. A pharmaceutical composition comprising a therapeutically effective amount of the compound according to claim 4 and a pharmaceutically acceptable carrier therefor.
- 6. A method of treating fungus infections in a subject in need of said treatment, which comprises administering to said subject an anti-fungal effective amount of the compound according to claim 4.
Priority Claims (1)
Number |
Date |
Country |
Kind |
38 32 362.1 |
Sep 1988 |
DEX |
|
Parent Case Info
This is a continuation of application Ser. No. 08/187,929, filed Jan. 27, 1994, which in turn is a continuation of application Ser. No. 07/874,277, filed Apr. 24, 1992, which in turn is a continuation of application Ser. No. 07/411,336, filed Sep. 22, 1989, all of which are now abandoned.
US Referenced Citations (1)
Number |
Name |
Date |
Kind |
3585111 |
Coats et al. |
Jun 1971 |
|
Non-Patent Literature Citations (4)
Entry |
Br. J. Cancer (1992) 65, 11-18. |
Cancer Res. vol. 51, pp. 4226-4233 (1991). |
Br. J. Cancer (1988) 57, 254-258. |
Br. J. Cancer (1987) 56, 55-67. |
Continuations (3)
|
Number |
Date |
Country |
Parent |
187929 |
Jan 1994 |
|
Parent |
874277 |
Apr 1992 |
|
Parent |
411336 |
Sep 1989 |
|