Claims
- 1. A process for recovering amino acids from acid protein hydrolysates comprising the steps of:
- (a) neutralizing the protein hydrolysates to immediately crystallize a first fraction enriched with leucine which is thereafter separated by filtration;
- (b) continuing crystallization of the neutralized protein hydrolysates for at least 3 days to obtain a second fraction enriched with cystine and tyrosine which is thereafter separated by filtration;
- (c) dissolving the leucine-rich fraction in aqueous acid to form a solution;
- (d) adjusting the isoleucine content of the solution to between 1.0 and 1.5% by total weight by the addition or removal of water;
- (e) oxidizing the methionine contained in the solution by the addition of oxidizing agents;
- (f) adjusting the pH of the solution to a value in the range of from 1.0 to 2.0 depending upon the tyrosine content in the solution to precipitate crude leucine which is separated by filtration; and
- (g) purifying the separated leucine by repeatedly dissolving leucine in aqueous acid and precipitating the leucine at a pH range of from 1.0 to 2.0 until the desired degree of purity is obtained.
Priority Claims (1)
Number |
Date |
Country |
Kind |
2906034 |
Feb 1979 |
DEX |
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Parent Case Info
This is a continuation of application Ser. No. 119,111, filed Feb. 6, 1980, now abandoned.
US Referenced Citations (6)
Foreign Referenced Citations (2)
Number |
Date |
Country |
49-1515 |
Jan 1974 |
JPX |
50-95221 |
Jul 1975 |
JPX |
Non-Patent Literature Citations (3)
Entry |
Tsuchiya, Chem. Abst., vol. 47, #3338e (1953). |
Geipel, Chem. Abst., vol. 70 #29303g (1969). |
Takayama et al., Chem. Abst., vol. 36, #44818 (1942). |
Continuations (1)
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Number |
Date |
Country |
Parent |
119111 |
Feb 1980 |
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