Claims
- 1. Tablets exhibiting, according to a test D, a “smooth in the mouth” texture, containing pulverulent sorbitol, the crystalline form of which is the γ form, having a sorbitol content higher than 95%, which exhibits:a hygroscopicity value, determined according to a test A, of less than 2%, said test A consisting in drawing the isothermal curve for water sorption at 20° C. which expresses the percentage of water uptake of a pulverulent product, dehydrated beforehand, which is placed in an atmosphere of variable relative humidity and at a temperature of 20° the hygroscopicity value being the percentage of water uptake at 60% equilibrium relative humidity, a specific surface, determined according to the BET method, at least equal to 2 m2/g, said test D consisting in an expert jury of 10 people evaluating blindly the “smooth in the mouth” texture of a series of convex tablets of the sorbitol to be tested, said tablets having a diameter of 13 mm, and being obtained on a Frogerais AP reciprocating press, after mixing at the time of tableting with 0.7% of magnesium stearate.
- 2. Tablets exhibiting, according to a test D, a “smooth in the mouth” texture, containing pulverulent sorbitol the crystalline form of which is the γ form, having a sorbitol content higher than 95%, which exhibits a specific surface according to the BET method of greater than 2.5 m2/g, said test D consisting in an expert jury of 10 people evaluating blindly the “smooth in the mouth” texture of a series of convex tablets of the sorbitol to be tested, said tablets having a diameter of 13 mm, and being obtained on a Frogerais AP reciprocating press, after mixing at the time of tableting with 0.7% of magnesium stearate.
Priority Claims (1)
Number |
Date |
Country |
Kind |
98 15681 |
Dec 1998 |
FR |
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CROSS-REFERENCE TO RELATED APPLICATIONS
This application is a Divisional of U.S. patent application Ser. No. 09/457,536, filed Dec. 9, 1999, now U.S. Pat. No. 6,274,778, the disclosure of which is being incorporated herein by reference in its entirety.
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Foreign Referenced Citations (2)
Number |
Date |
Country |
0 032 288 |
Jul 1981 |
EP |
2 046 743 |
Nov 1980 |
GB |
Non-Patent Literature Citations (2)
Entry |
CA:66:12102 abs of DD49322 Aug. 1966.* |
Brunauer S., Journal of the American Chemical Society, 1938, 60, pp 309-319. |