The present invention relates in general to surgically implantable fluid injection ports, and is particularly directed to fasteners and methods for fastening subcutaneous peripherally attached ports. The invention will be specifically disclosed in connection with injection ports used with adjustable gastric bands, although the fasteners of the present invention may be used with many different subcutaneously attached devices, including injection ports used for vascular access such as the infusion of medications and blood draws.
Injection ports are placed beneath the skin of a body for injecting fluids into the body, such as for infusing medication, blood draws, and many other applications, including adjustable gastric bands. Since the early 1980s, adjustable gastric bands have provided an effective alternative to gastric bypass and other irreversible surgical weight loss treatments for the morbidly obese. The gastric band is wrapped around an upper portion of the patient's stomach, forming a stoma that restricts food passing from an upper portion to a lower portion of the stomach. When the stoma is of the appropriate size, food held in the upper portion of the stomach provides a feeling of fullness that discourages overeating. However, initial maladjustment or a change in the stomach over time may lead to a stoma of an inappropriate size, warranting an adjustment of the gastric band. Otherwise, the patient may suffer vomiting attacks and discomfort when the stoma is too small to reasonably pass food. At the other extreme, the stoma may be too large and thus fail to slow food moving from the upper portion of the stomach, defeating the purpose altogether for the gastric band.
In addition to a latched position to set the outer diameter of the gastric band, adjustability of gastric bands is generally achieved with an inwardly directed inflatable balloon, similar to a blood pressure cuff, into which fluid, such as saline, is injected through a fluid injection port to achieve a desired diameter. Since adjustable gastric bands may remain in the patient for long periods of time, the fluid injection port is typically installed subcutaneously to avoid infection, for instance in front of the sternum. Adjusting the amount of fluid in the adjustable gastric band is achieved by inserting a Huber needle through the skin into a silicon septum of the injection port. Once the needle is removed, the septum seals against the hole by virtue of compressive load generated by the septum. A flexible conduit communicates between the injection port and the adjustable gastric band.
As described herein, there is provided an injection port for injecting fluids into a body. The port includes a housing for placement beneath the skin of the body and means for receiving a needle. At least one retention member is integrally attached to the housing which is moveable with respect thereto. The retention member has an undeployed state when disposed in a first position relative to the housing and a deployed state engaging tissue adjacent the housing when disposed in a second position relative to the housing.
The accompanying drawings incorporated in and forming a part of the specification illustrate several aspects of the present invention, and together with the description serve to explain the principles of the invention. In the drawings:
Reference will now be made in detail to the present preferred embodiment of the invention, an example of which is illustrated in the accompanying drawings.
Referring now to the drawings in detail, wherein like numerals indicate the same elements throughout the views,
Referring also to
Although a specific configuration for injection port 18 is disclosed herein, there are many suitable configurations which may be used in conjunction with the present invention.
As shown in
Each flange 34a and 34b includes a respective mutually aligned hole into which pin 32 is pressed with an interference fit sufficient to retain pin 32 therein. In the depicted embodiment, ribs 38a and 38b extend from the facing inner surfaces of flanges 34a and 34b, and bear against fasteners 30 to keep them from rotating freely so that fasteners 30 may be kept a non-deployed state until implantation.
Flange 22 includes two circumferentially spaced recesses 40 (only one of which is visible in
The teachings of this invention may be practiced with any suitable configuration of a injection port, such as having a smaller flange or a discontinuous flange. Three fasteners 30 are effective to prevent injection port 18 from flipping over after implantation, such as due to passive or induced movements of the patient. However, the present invention is not limited to the use of three fasteners, and one or more fasteners may be used.
Referring to
Referring also to
Base 46 includes two circumferentially spaced resilient retention members 60, each defined by two respective elongated slots 62a and 62b. Each pair of slots 62a and 62b are circumferentially spaced a distance such that retention members 60 are essentially cantilevered springs which may be deflected outwardly to release injection port 18, as will be described below. Extending from each longitudinal edge of each retention member 60 near end 60a is a respective retention member actuator 64a and 64b. End 60a includes an inwardly extending lip 60b. The arcuate width, height and depth of recess 40 are complementary to the corresponding dimensions of lip 60b, such that lip 60b engages recess 40 to thereby retain injection port 18 at end 54 of base 42.
As seen in
Cylindrical portion 68 includes pairs of spaced apart, outwardly extending actuators 76a and 76b. Actuators 76a and 76b are depicted as ramps, having inclined leading surfaces 78a and 78b and declined trailing surfaces 80 and 80b. When plunger 48 is disposed within base 46, each actuator 76a and 76b is disposed within a respective slot 62a and 62b. As will be described below, as plunger is depressed to advance end 70 toward end 54, actuators 76a and 76b engage respective resilient member actuators 64a and 64b and urge them outwardly, causing resilient members 60 to move outwardly, and eventually moving lips 60b out of respective recesses 22c, releasing injection port 18 from applicator subassembly 44.
Referring to
Referring also to
Referring to
It is noted that in the embodiment depicted in
Referring to
Referring also to
As seen in
Referring to
Referring to
As depicted, in the undeformed deployed state, each fastener 138 is a single coil, forming a hook shape, with distal end 138b disposed touching or otherwise adjacent the side of housing 140 of injection port 136. It is noted that the relative positions of the side of housing 140 and distal ends 138b may leave fasteners 138 in a somewhat deformed state with some stress and strain. Fasteners 138, also referred to as radial elements, are flexible, being made of any suitable material. Material having super elastic properties, such as a nickel titanium alloy, for example Nitinol® wire.
Fasteners 138 may be of any suitable dimensions. In one example, Nitinol® wire having a diameter in the range of 0.020-0.080 mm, coiled to a diameter of about 4-8 mm was used.
Referring also to
As seen in
Although
Injection port 136 may be releasably held in the appropriate location within tube 146 in any suitable manner. For example, a pin may extend through a hole in tube 146 to restrain injection port 136 across bottom 1364a until implantation; an adequate frictional fit between injection port 136 and the inside of tube 146 may be provided, with the tightest fit being at the highest location of injection port 136 within tube 146; end 144a could be configured to releasably engage injection port 44, with plunger 144 being retained in tube 146.
It is contemplated, but not required, that applier 142 will be provided to the surgeon with injection port 136 premounted inside of tube 144 as a sterilized assembly. Implantation of self attaching injection port 136 is accomplished by urging end 146a against fascia layer 150 to depress the tissue surface slightly thereby upraising the tissue so that fasteners 138 may go through it. The surgeon then pushers plunger 144 to deploy fasteners 138, and withdraws tube 146. Sharp tips 138b penetrate through and curl back out of fascia layer 150, and stop against the side of housing 140 to protect tips 138b. In the deployed state, fasteners 138 are in a “relaxed” configuration, having less deformation, and therefore less stress strain, than in the pre-attachment, deformed state.
Deformable fasteners 138 may be sized to provide holding strength similar to sutures, with the flexibility of fasteners 138 allowing injection port 136 to be removed without the tissue being ripped. For example, after attachment, injection port may be reposition by grasping injection port 136 and pulling it up, uncurling fasteners 138 in the process. It may then be reinserted into applier 142 and reimplanted. Applier 142 may also be used to remove injection port 136, such as by configuring end 150a to engage injection port 136 to be withdrawn, as tube 146 is urged against tissue. In such a case, it may be advantageous to provide structure to index plunger 144 relative to injection port 136 and slots 148.
Although flexible fasteners 138 are illustrated extending from bottom 136a, this aspect of the present invention may be practiced with fasteners 146 extending in other directions from injection port 136, such as from the side. As will be appreciated, modifications to applier 142, such as a larger diameter to accommodate the circumferential attachment to injection port 136 for implantation, may be made. It is noted that with flexible fasteners 138 extending from bottom 136a, tips 138a are oriented in a downward pointing undeployed state at a position ready to penetrate the tissue from the top, which allows a smaller diameter than would fasteners extending outwardly from the side. A small diameter applier minimizes the size of the incision, and requires less dissection.
Referring to
Hinge 158 is carried by annular flange 156, moveably connecting retention member/fastener 160 to flange 156. Hinge 158 may be any structure which allows the necessary relative movement between retention member/fastener 160 and flange 156.
Referring also to
In the embodiment depicted, flange 156 includes opening 164 which is shaped complementary to locking member 162, configured to receive locking member 162 and engage step 162c to maintain locking member 162 and retention member/fastener 160 in the deployed state. Locking member 162 has enough flexibility to allow outward movement of locking member 162 as inclined surface 162d engages and advances along corresponding edge 164a of opening 164. Once locking member 162 has been inserted far enough into opening 164 for ramp 162d to disengage with corresponding edge 164a, step 162c will clear upper surface 156a, and the locking member 162 will move inwardly, with step 162c engaging upper surface 156a to resist withdrawal of locking member 162 from opening 164.
Alternatively, opening 164 may open to outer edge 156c of flange 156, or may even be eliminated, with locking member 162 disposed such that inclined surface 162d engages and advances along outer edge 156c.
Locking member 162 may be made of any suitable material which provides the necessary flexibility, including plastic. Locking member 162 is not limited to the shape shown, and may be of any shape which is functional to retain retention member 162 at the position shown in the deployed state. Locking member 162 and flange 156 may be configured such that distal tip 162a does not extend above, or as far above, upper surface 154a. For example, locking member 162 could include a stop surface which engages the annular flange 156 so as to limit the position of distal tip 162a relative to upper surface 156a.
Retention member 160 may also be made of any suitable material, including plastic.
Although retention member/fastener 160 is illustrated as shaped complementary to flange 156, retention member/fastener 160 does not have to have the same shape as flange 156. For example, retention member/fastener 160 could be a strap. Additionally, housing 154 does not have to include flange 156. Flange 156 could be omitted, with hinge 158 being connected directly to an edge of the distal end of housing 154. The axis of rotation of retention member 160 could be oriented vertically with respect to housing 154 and lower surface 156b of housing 154.
In summary, numerous benefits have been described which result from employing the concepts of the invention. The foregoing description of one or more embodiments of the invention has been presented for purposes of illustration and description. It is not intended to be exhaustive or to limit the invention to the precise form disclosed. Obvious modifications or variations are possible in light of the above teachings. The one or more embodiments were chosen and described in order to best illustrate the principles of the invention and its practical application to thereby enable one of ordinary skill in the art to best utilize the invention in various embodiments and with various modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims appended hereto.
This application is a continuation of U.S. patent application Ser. No. 10/741,875, entitled “Subcutaneous Self Attaching Injection Port with Integral Moveable Retention Members,” filed Dec. 19, 2003, now U.S. Pat. No. 7,862,546, which claims the priority of U.S. Provisional Patent Application Ser. No. 60/478,763, entitled “Fluid Injection Port For Adjustable Gastric Band,” filed Jun. 16, 2003, the disclosure of which is incorporated herein by reference. This application also incorporates by reference the following United States Patent Applications: U.S. patent application Ser. No. 10/741,127, filed Dec. 19, 2003, entitled “Subcutaneous Injection Port for Applied Fasteners,” published as U.S. Patent Publication No. 2005/0131352; and U.S. patent application Ser. No. 10/741,868, filed Dec. 19, 2003, entitled “Subcutaneous Self Attaching Injection Port With Integral Fasteners,” now U.S. Pat. No. 7,374,557.
Number | Name | Date | Kind |
---|---|---|---|
2737954 | Knapp | Mar 1956 | A |
3371352 | Siposs et al. | Mar 1968 | A |
3587115 | Shiley | Jun 1971 | A |
3686740 | Shiley | Aug 1972 | A |
3850324 | Meyer | Nov 1974 | A |
4378023 | Trabucco | Mar 1983 | A |
4543088 | Bootman et al. | Sep 1985 | A |
4569675 | Prostl et al. | Feb 1986 | A |
4592339 | Kuzmak et al. | Jun 1986 | A |
4621640 | Mulhollan et al. | Nov 1986 | A |
4665906 | Jervis | May 1987 | A |
4673394 | Fenton, Jr. et al. | Jun 1987 | A |
4685447 | Iverson et al. | Aug 1987 | A |
4692146 | Hilger | Sep 1987 | A |
4704103 | Stober et al. | Nov 1987 | A |
4710174 | Moden et al. | Dec 1987 | A |
4723948 | Clark et al. | Feb 1988 | A |
4732948 | McCready et al. | Mar 1988 | A |
4738023 | Fabris | Apr 1988 | A |
4738657 | Hancock et al. | Apr 1988 | A |
4762517 | McIntyre et al. | Aug 1988 | A |
4767410 | Moden et al. | Aug 1988 | A |
4772261 | Von Hoff et al. | Sep 1988 | A |
4772270 | Wiita et al. | Sep 1988 | A |
4778452 | Moden et al. | Oct 1988 | A |
4781680 | Redmond et al. | Nov 1988 | A |
4781695 | Dalton | Nov 1988 | A |
4798584 | Hancock et al. | Jan 1989 | A |
4802885 | Weeks et al. | Feb 1989 | A |
4834720 | Blinkhorn | May 1989 | A |
4840615 | Hancock et al. | Jun 1989 | A |
4861341 | Woodburn | Aug 1989 | A |
4880414 | Whipple | Nov 1989 | A |
4892518 | Cupp et al. | Jan 1990 | A |
4898585 | Borsanyi et al. | Feb 1990 | A |
4904241 | Bark | Feb 1990 | A |
4925445 | Sakamoto et al. | May 1990 | A |
4929230 | Pfleger | May 1990 | A |
4929236 | Sampson | May 1990 | A |
4969873 | Steinbach et al. | Nov 1990 | A |
4976715 | Bays et al. | Dec 1990 | A |
4978338 | Melsky et al. | Dec 1990 | A |
5006115 | McDonald | Apr 1991 | A |
5013298 | Moden et al. | May 1991 | A |
5026344 | Dijkstra et al. | Jun 1991 | A |
5041098 | Loiterman et al. | Aug 1991 | A |
5045060 | Melskky et al. | Sep 1991 | A |
5053013 | Ensminger et al. | Oct 1991 | A |
5090954 | Geary | Feb 1992 | A |
5108377 | Cone et al. | Apr 1992 | A |
5123199 | Lysohir et al. | Jun 1992 | A |
5129891 | Young | Jul 1992 | A |
5133753 | Bark et al. | Jul 1992 | A |
5137529 | Watson et al. | Aug 1992 | A |
5158547 | Doan et al. | Oct 1992 | A |
5174487 | Rothfuss et al. | Dec 1992 | A |
5178612 | Fenton, Jr. | Jan 1993 | A |
5185003 | Brethauer | Feb 1993 | A |
5203864 | Phillips | Apr 1993 | A |
5207644 | Strecker | May 1993 | A |
5213574 | Tucker | May 1993 | A |
5217486 | Rice et al. | Jun 1993 | A |
5226429 | Kuzmak | Jul 1993 | A |
5246156 | Rothfuss et al. | Sep 1993 | A |
5261914 | Warren | Nov 1993 | A |
5263930 | Ensminger | Nov 1993 | A |
5279564 | Taylor | Jan 1994 | A |
5281199 | Ensminger et al. | Jan 1994 | A |
5290297 | Phillips | Mar 1994 | A |
5305202 | Gallant et al. | Apr 1994 | A |
5318545 | Tucker | Jun 1994 | A |
5324518 | Orth et al. | Jun 1994 | A |
5328465 | Kratoska et al. | Jul 1994 | A |
5332398 | Miller et al. | Jul 1994 | A |
5333772 | Rothfuss et al. | Aug 1994 | A |
5336194 | Polaschegg | Aug 1994 | A |
5350360 | Ensminger et al. | Sep 1994 | A |
5360407 | Leonard et al. | Nov 1994 | A |
5364408 | Gordon | Nov 1994 | A |
5381943 | Allen et al. | Jan 1995 | A |
5387192 | Glantz et al. | Feb 1995 | A |
5399168 | Wadsworth, Jr. et al. | Mar 1995 | A |
5417656 | Ensminger et al. | May 1995 | A |
5423857 | Rosenman et al. | Jun 1995 | A |
5445616 | Kratoska et al. | Aug 1995 | A |
5464407 | McGuire | Nov 1995 | A |
5470010 | Rothfuss et al. | Nov 1995 | A |
5476460 | Montalvo | Dec 1995 | A |
5503630 | Ensminger et al. | Apr 1996 | A |
5527277 | Ensminger et al. | Jun 1996 | A |
5527278 | Ensminger et al. | Jun 1996 | A |
5527321 | Hinchliffe | Jun 1996 | A |
5540648 | Yoon | Jul 1996 | A |
5545152 | Funderburk et al. | Aug 1996 | A |
5558641 | Glantz et al. | Sep 1996 | A |
5562618 | Cai et al. | Oct 1996 | A |
5573540 | Yoon | Nov 1996 | A |
5582616 | Bolduc et al. | Dec 1996 | A |
5588581 | Conlon et al. | Dec 1996 | A |
5591143 | Trombley, III et al. | Jan 1997 | A |
5601224 | Bishop et al. | Feb 1997 | A |
5601604 | Vincent | Feb 1997 | A |
5602224 | Vrckovnik et al. | Feb 1997 | A |
5613945 | Cai et al. | Mar 1997 | A |
5632729 | Cai et al. | May 1997 | A |
5634584 | Okorocha et al. | Jun 1997 | A |
5635718 | De Puydt et al. | Jun 1997 | A |
5637102 | Tolkoff et al. | Jun 1997 | A |
5653718 | Yoon | Aug 1997 | A |
5681330 | Hughett et al. | Oct 1997 | A |
5683447 | Bush et al. | Nov 1997 | A |
5688247 | Haindl et al. | Nov 1997 | A |
5700272 | Gordon et al. | Dec 1997 | A |
5716370 | Williamson, IV et al. | Feb 1998 | A |
5718682 | Tucker | Feb 1998 | A |
5743873 | Cai et al. | Apr 1998 | A |
5792104 | Speckman et al. | Aug 1998 | A |
5792123 | Ensminger | Aug 1998 | A |
5810882 | Bolduc et al. | Sep 1998 | A |
5817062 | Flom et al. | Oct 1998 | A |
5829662 | Allen et al. | Nov 1998 | A |
5830221 | Stein et al. | Nov 1998 | A |
5853394 | Tolkoff et al. | Dec 1998 | A |
5871532 | Schroeppel | Feb 1999 | A |
RE36176 | Kuzmak | Mar 1999 | E |
5902598 | Chen et al. | May 1999 | A |
5954687 | Baudino | Sep 1999 | A |
5976159 | Bolduc et al. | Nov 1999 | A |
5989216 | Johnson et al. | Nov 1999 | A |
6001386 | Ashton et al. | Dec 1999 | A |
6086555 | Eliasen et al. | Jul 2000 | A |
6102922 | Jakobsson et al. | Aug 2000 | A |
6213973 | Eliasen et al. | Apr 2001 | B1 |
6251090 | Avery et al. | Jun 2001 | B1 |
6290702 | Fucci et al. | Sep 2001 | B1 |
6319226 | Sherry | Nov 2001 | B1 |
6447524 | Knodel et al. | Sep 2002 | B1 |
6461292 | Forsell | Oct 2002 | B1 |
6470892 | Forsell | Oct 2002 | B1 |
6478783 | Moorehead | Nov 2002 | B1 |
6511490 | Robert | Jan 2003 | B2 |
6527754 | Tallarida et al. | Mar 2003 | B1 |
6540717 | Sherry | Apr 2003 | B2 |
6556857 | Estes et al. | Apr 2003 | B1 |
6592571 | Verbeek et al. | Jul 2003 | B1 |
6607504 | Haarala et al. | Aug 2003 | B2 |
6827722 | Schoenefeld | Dec 2004 | B1 |
6962577 | Tallarida et al. | Nov 2005 | B2 |
6976159 | Poduska et al. | Dec 2005 | B1 |
6988987 | Ishikawa et al. | Jan 2006 | B2 |
7033335 | Haarala et al. | Apr 2006 | B2 |
7076309 | Hine et al. | Jul 2006 | B2 |
7097770 | Lysenko et al. | Aug 2006 | B2 |
7138179 | Kim et al. | Nov 2006 | B2 |
7152601 | Barakat et al. | Dec 2006 | B2 |
7152926 | Wrobel | Dec 2006 | B2 |
7195774 | Carvalho et al. | Mar 2007 | B2 |
7223239 | Schulze et al. | May 2007 | B2 |
7241632 | Yang | Jul 2007 | B2 |
7341577 | Gill | Mar 2008 | B2 |
7374557 | Conlon et al. | May 2008 | B2 |
7387635 | Keller | Jun 2008 | B2 |
7442165 | Forsell | Oct 2008 | B2 |
7553298 | Hunt et al. | Jun 2009 | B2 |
7561916 | Hunt et al. | Jul 2009 | B2 |
7590452 | Imran et al. | Sep 2009 | B2 |
7608080 | Shipp et al. | Oct 2009 | B2 |
7621863 | Forsell | Nov 2009 | B2 |
7651483 | Byrum et al. | Jan 2010 | B2 |
7762998 | Birk et al. | Jul 2010 | B2 |
7762999 | Byrum | Jul 2010 | B2 |
7806876 | Sherry | Oct 2010 | B2 |
7850660 | Uth et al. | Dec 2010 | B2 |
7862546 | Conlon et al. | Jan 2011 | B2 |
8007479 | Birk et al. | Aug 2011 | B2 |
8007747 | Giter et al. | Aug 2011 | B2 |
8029477 | Byrum et al. | Oct 2011 | B2 |
8079989 | Birk et al. | Dec 2011 | B2 |
8162897 | Byrum | Apr 2012 | B2 |
8211127 | Uth et al. | Jul 2012 | B2 |
20030181890 | Schulze et al. | Sep 2003 | A1 |
20040068233 | DiMatteo | Apr 2004 | A1 |
20040093056 | Johnson et al. | May 2004 | A1 |
20040199129 | DiMatteo | Oct 2004 | A1 |
20040220682 | Levine et al. | Nov 2004 | A1 |
20040249362 | Levine et al. | Dec 2004 | A1 |
20050131352 | Conlon et al. | Jun 2005 | A1 |
20050148956 | Conlon et al. | Jul 2005 | A1 |
20050277899 | Conlon et al. | Dec 2005 | A1 |
20050283119 | Uth et al. | Dec 2005 | A1 |
20060178647 | Stats | Aug 2006 | A1 |
20060190039 | Birk et al. | Aug 2006 | A1 |
20060217668 | Schulze et al. | Sep 2006 | A1 |
20060217673 | Schulze et al. | Sep 2006 | A1 |
20060234445 | Yang | Oct 2006 | A1 |
20060293626 | Byrum et al. | Dec 2006 | A1 |
20070208313 | Conlon et al. | Sep 2007 | A1 |
20070255306 | Conlon et al. | Nov 2007 | A1 |
20070293829 | Conlon et al. | Dec 2007 | A1 |
20100217199 | Uth et al. | Aug 2010 | A1 |
20100217200 | Uth et al. | Aug 2010 | A1 |
20100234808 | Uth et al. | Sep 2010 | A1 |
20100286649 | Birk et al. | Nov 2010 | A1 |
20110152901 | Woodruff et al. | Jun 2011 | A1 |
Number | Date | Country |
---|---|---|
2004281641 | May 2010 | AU |
2006202145 | Dec 2012 | AU |
1600281 | Mar 2005 | CN |
42 11 045 | Oct 1993 | DE |
197 45 654 | Apr 1999 | DE |
197 51 791 | May 1999 | DE |
0 858 814 | Aug 1998 | EP |
1 057 457 | Dec 2000 | EP |
1 346 753 | Sep 2003 | EP |
1 488 824 | Dec 2004 | EP |
1 662 971 | Jun 2006 | EP |
1 670 362 | Jun 2006 | EP |
1 676 527 | Jul 2006 | EP |
1 704 891 | Sep 2006 | EP |
1 736 123 | Dec 2006 | EP |
1 736 197 | Dec 2006 | EP |
1 736 198 | Dec 2006 | EP |
1 832 252 | Sep 2007 | EP |
62-281966 | Dec 1987 | JP |
2-119877 | May 1990 | JP |
03-275075 | Dec 1991 | JP |
8-107934 | Apr 1996 | JP |
2000-093524 | Apr 2000 | JP |
2005-007171 | Jan 2005 | JP |
2007-505696 | Mar 2007 | JP |
1823791 | Nov 2006 | RU |
1823791 | Jun 1993 | SU |
WO 9422520 | Oct 1994 | WO |
WO 9640357 | Dec 1996 | WO |
WO 9701370 | Jan 1997 | WO |
WO 9730659 | Aug 1997 | WO |
WO 9926543 | Jun 1999 | WO |
WO 9934859 | Jul 1999 | WO |
WO 0033901 | Jun 2000 | WO |
WO 0180926 | Nov 2001 | WO |
WO 02053220 | Jul 2002 | WO |
WO 02743810 | Sep 2002 | WO |
WO 2004026152 | Apr 2004 | WO |
WO 2005037055 | Apr 2005 | WO |
WO 2005072627 | Aug 2005 | WO |
Entry |
---|
U.S. Appl. No. 60/478,763, filed Jun. 16, 2003, Conlon et al. |
U.S. Appl. No. 60/503,074, filed Sep. 15, 2003, Birk et al. |
Australian Search Report dated Aug. 31, 2007 for Application No. SG200604149-5. |
Australian Search Report and Written Opinion dated Nov. 20, 2007 for Application No. SG200604066. |
EPO Search Report dated Aug. 19, 2004 for Application No. 04253581. |
EPO Search Report dated Oct. 4, 2005 for Application No. 05253363. |
EPO Search Report dated Oct. 4, 2006 for Application No. 06253285. |
EPO Search Report dated Oct. 16, 2006 for Application No. 06253284. |
EPO Search Report dated Nov. 17, 2006 for Application No. 06253284. |
Partial EPO Search Report dated Oct. 30, 2006 for Application No. 06253276. |
Examination Report dated Nov. 24, 2006 for Application No. 04253581. |
Extended EPO Search Report dated Jan. 16, 2007 for Application No. 06253276. |
Examination Report dated Oct. 22, 2007 for Application No. 04253581. |
Examination Report dated Nov. 30, 2006 for Application No. 05253363. |
Examination Report dated Jan. 18, 2008 for Application No. 05253363. |
Examination Report dated Jul. 10, 2008 for Application No. 05253363. |
Examination Report dated Jan. 15, 2009 for Application No. 04253581. |
Abstract for DE 42 11 045. |
Abstract for EP 0 858 814. |
Australian Search Report dated Jul. 16, 2007 for Singaporean Application No. SG 200604063. |
Australian Search Report dated Sep. 7, 2007 for Singaporean Application No. SG 206604149. |
Australian Examiner's Report dated Apr. 22, 2010 for Application No. AU 2005202292. |
Australian Examiner's Report dated Mar. 19, 2012 for Application No. AU 2006202145. |
Austrian Written Opinion dated Nov. 30, 2007 for Singaporean Application No. SG 200604066. |
European Patent Office Opposition Decision dated Feb. 4, 2011 for Application No. EP 06253277. |
Response in Appeal of Opposition Decision from European Patent Office dated Nov. 8, 2011 for Application No. EP 06253277. |
European Search Report dated Oct. 13, 2006 for Application No. 06253285. |
Japanese Office Action dated Dec. 24, 2010 for Application No. JP 2005-160203. |
Abstract and English Machine Translation of Japanese Patent No. JP 2000-093524. |
Office Action dated Dec. 27, 2010 for U.S. Appl. No. 11/471,767. |
Office Action dated Jun. 9, 2011 for U.S. Appl. No. 11/471,767. |
Notice of Allowance dated Sep. 21, 2011 for U.S. Appl. No. 11/471,767. |
Notice of Allowance dated Jan. 27, 2012 for U.S. Appl. No. 11/471,767. |
Notice of Allowance dated Jul. 11, 2012 for U.S. Appl. No. 12/770,047. |
Restriction Requirement dated Jun. 24, 2011 for U.S. Appl. No. 12/769,890. |
Office Action dated Aug. 15, 2011 for U.S. Appl. No. 12/769,890. |
Notice of Allowance dated Mar. 7, 2012 for U.S. Appl. No. 12/769,890. |
Office Action dated Apr. 5, 2011 for U.S. Appl. No. 12/769,914. |
Office Action dated Oct. 4, 2011 for U.S. Appl. No. 12/769,914. |
Office Action dated Apr. 5, 2011 for U.S. Appl. No. 12/769,929. |
Ex Parte Quayle Action dated Oct. 18, 2011 for U.S. Appl. No. 12/769,929. |
Restriction Requirement dated Aug. 28, 2006 for U.S. Appl. No. 10/741,875. |
Office Action dated Nov. 2, 2006 for U.S. Appl. No. 10/741,875. |
Office Action dated Jun. 25, 2007 for U.S. Appl. No. 10/741,875. |
Office Action dated Dec. 17, 2007 for U.S. Appl. No. 10/741,875. |
Office Action dated May 27, 2008 for U.S. Appl. No. 10/741,875. |
Office Action dated Oct. 27, 2008 for U.S. Appl. No. 10/741,875. |
Office Action dated Mar. 20, 2009 for U.S. Appl. No. 10/741,875. |
Office Action dated Oct. 2, 2009 for U.S. Appl. No. 10/741,875. |
Notice of Allowance dated Apr. 9, 2010 for U.S. Appl. No. 10/741,875. |
Notice of Allowance dated Sep. 1, 2010 for U.S. Appl. No. 10/741,875. |
Office Action dated May 16, 2007 for U.S. Appl. No. 11/166,625. |
Office Action dated Oct. 22, 2007 for U.S. Appl. No. 11/166,625. |
Office Action dated Jan. 14, 2008 for U.S. Appl. No. 11/166,625. |
Office Action dated Jul. 23, 2008 for U.S. Appl. No. 11/166,625. |
Office Action dated Mar. 20, 2009 for U.S. Appl. No. 11/166,625. |
Office Action dated Sep. 3, 2009 for U.S. Appl. No. 11/166,625. |
Office Action dated Mar. 19, 2010 for U.S. Appl. No. 11/166,625. |
Office Action dated Mar. 29, 2011 for U.S. Appl. No. 11/166,625. |
Notice of Allowance dated May 16, 2011 for U.S. Appl. No. 11/166,625. |
Office Action dated Apr. 12, 2007 for U.S. Appl. No. 11/166,610. |
Office Action dated Oct. 17, 2007 for U.S. Appl. No. 11/166,610. |
Office Action dated Jan. 15, 2008 for U.S. Appl. No. 11/166,610. |
Office Action dated Jul. 14, 2008 for U.S. Appl. No. 11/166,610. |
Office Action dated Dec. 29, 2008 for U.S. Appl. No. 11/166,610. |
Office Action dated Jun. 3, 2009 for U.S. Appl. No. 11/166,610. |
Notice of Allowance dated Jan. 15, 2010 for U.S. Appl. No. 11/166,610. |
Notice of Allowance dated Feb. 1, 2010 for U.S. Appl. No. 11/166,610. |
Notice of Allowance dated Sep. 7, 2010 for U.S. Appl. No. 11/166,610. |
Restriction Requirement dated Nov. 27, 2006 for U.S. Appl. No. 10/741,868. |
Office Action dated Mar. 7, 2007 for U.S. Appl. No. 10/741,868. |
Office Action dated Sep. 7, 2007 for U.S. Appl. No. 10/741,868. |
Notice of Allowance dated Jan. 14, 2008 for U.S. Appl. No. 10/741,868. |
Office Action dated Feb. 27, 2008 for U.S. Appl. No. 11/166,611. |
Office Action dated Jul. 31, 2008 for U.S. Appl. No. 11/166,611. |
Office Action dated Oct. 20, 2008 for U.S. Appl. No. 11/166,611. |
Notice of Allowance dated May 19, 2009 for U.S. Appl. No. 11/166,611. |
Notice of Allowance dated Sep. 25, 2009 for U.S. Appl. No. 11/166,611. |
Office Action dated Aug. 15, 2007 for U.S. Appl. No. 11/166,283. |
Office Action dated Jan. 8, 2008 for U.S. Appl. No. 11/166,283. |
Notice of Allowance dated Jun. 17, 2008 for U.S. Appl. No. 11/166,283. |
Notice of Allowance dated Nov. 3, 2008 for U.S. Appl. No. 11/166,283. |
Notice of Allowance dated Mar. 4, 2009 for U.S. Appl. No. 11/166,283. |
Office Action dated Aug. 10, 2007 for U.S. Appl. No. 11/166,702. |
Office Action dated Jan. 8, 2008 for U.S. Appl. No. 11/166,702. |
Office Action dated Sep. 25, 2008 for U.S. Appl. No. 11/166,702. |
Office Action dated Feb. 13, 2009 for U.S. Appl. No. 11/166,702. |
Office Action dated May 14, 2009 for U.S. Appl. No. 11/166,702. |
Office Action dated Dec. 4, 2009 for U.S. Appl. No. 11/166,702. |
Office Action dated Jun. 7, 2010 for U.S. Appl. No. 11/166,702. |
Notice of Allowance dated Dec. 13, 2010 for U.S. Appl. No. 11/166,702. |
Office Action dated Jul. 23, 2007 for U.S. Appl. No. 11/166,968. |
Restriction Requirement dated Jan. 2, 2008 for U.S. Appl. No. 11/166,968. |
Office Action dated Apr. 18, 2008 for U.S. Appl. No. 11/166,968. |
Office Action dated Sep. 8, 2008 for U.S. Appl. No. 11/166,968. |
Restriction Requirement dated Feb. 13, 2009 for U.S. Appl. No. 11/166,968. |
Notice of Allowance dated Apr. 6, 2009 for U.S. Appl. No. 11/166,968. |
Office Action dated Jul. 12, 2007 for U.S. Appl. No. 10/858,614. |
Office Action dated Nov. 14, 2007 for U.S. Appl. No. 10/858,614. |
Office Action dated Mar. 31, 2008 for U.S. Appl. No. 10/858,614. |
Office Action dated Nov. 13, 2008 for U.S. Appl. No. 10/858,614. |
Office Action dated Apr. 15, 2009 for U.S. Appl. No. 10/858,614. |
Office Action dated Oct. 27, 2009 for U.S. Appl. No. 10/858,614. |
Office Action dated Mar. 28, 2007 for U.S. Appl. No. 10/741,127. |
Office Action dated Sep. 11, 2007 for U.S. Appl. No. 10/741,127. |
Office Action dated Jan. 8, 2008 for U.S. Appl. No. 10/741,127. |
Office Action dated Jul. 7, 2008 for U.S. Appl. No. 10/741,127. |
Australian Examiner's Report dated May 17, 2013 for Application No. AU 2012254952. |
Canadian Office Action dated May 22, 2013 for Application No. CA 2508648. |
Japanese Office Action dated Aug. 6, 2013 for Application No. JP 2007-162956. |
Office Action Final dated Sep. 30, 2013 for U.S. Appl. No. 12/769,914. |
Notice of Allowance dated Oct. 1, 2013 for U.S. Appl. No. 12/769,929. |
U.S. Appl. No. 12/769,883, filed Apr. 29, 2010. |
European Search Report dated Apr. 26, 2011 for Application No. 10177441. |
European Search Report dated Mar. 31, 2011 for Application No. 10177808. |
European Search Report dated Oct. 4, 2006 for Application No. 06253277. |
European Search Report dated Oct. 18, 2007 for Application No. 07252500. |
Partial European Search Report dated Sep. 27, 2006 for Application No. 06253283. |
Partial European Search Report dated Aug. 4, 2009 for Application No. 08251093. |
EPO Notice of Opposition to a European Patent dated Sep. 2, 2009 for European Application No. and Patent No. 06 253 277.5 / 1 736 197. |
EPO Response to Attend Oral Proceedings dated Nov. 8, 2010 for European Application No. And Patent No. 06 253 277.5 / 1 736 197. |
European Examination report dated Mar. 4, 2009 for Application No. 06 253 283.3. |
Australian Examiner's Report dated Feb. 25, 2011 for Application No. AU 2006202145. |
Australian Examiner's Report dated Jun. 2, 2009 for Application No. AU 2004202549. |
Australian Examiner's Report dated Feb. 18, 2011 for Application No. AU 2006202115. |
Australian Examiner's Report dated Sep. 27, 2011 for Application No. AU 2011200887. |
Australian Examiner's Report dated Dec. 21, 2011 for Application No. AU 2011200887. |
Australian Examiner's Report dated Apr. 18, 2012 for Application No. AU 2007202311. |
Canadian Office Action dated Apr. 11, 2011 for Application No. CA 2471185. |
Canadian Office Action dated Nov. 9, 2011 for Application No. CA 2508648. |
Canadian Office Action dated Sep. 19, 2012 for Application No. CA 2508648. |
Canadian Office Action dated Nov. 7, 2012 for Application No. CA 2549219. |
Canadian Office Action dated Nov. 6, 2012 for Application No. CA 2549241. |
Canadian Office Action dated Mar. 19, 2013 for Application No. CA 2590827. |
Chinese Office Action dated Apr. 20, 2007 for Application No. CN 200410069447.0. |
Chinese Office Action dated Jan. 12, 2012 for Application No. CN 200610093155X. |
Chinese Office Action dated Dec. 22, 2011 for Application No. CN 200610093156.4. |
Chinese Office Action dated Apr. 19, 2012 for Application No. CN 200610093156.4. |
Chinese Office Action dated Jun. 22, 2010 for Application No. CN 200710112538.1. |
Chinese Office Action dated Jul. 6, 2011 for Application No. CN 200710112538.1. |
Chinese Office Action dated Apr. 5, 2012 for Application No. CN 200710112538.1. |
Israeli Office Action dated Dec. 8, 2009 for Application No. IL 175828. |
Israeli Office Action dated Dec. 14, 2009 for Application No. IL 175851. |
Japanese Office Action dated Nov. 8, 2011 for Application No. JP 2005-160203. |
Japanese Office Action dated Dec. 14, 2006 for Application No. JP 2004-177065. |
Japanese Office Action dated Jun. 25, 2010 for Application No. JP 2004-177065. |
Japanese Office Action dated Feb. 23, 2011 for Application No. JP 2004-177065. |
Japanese Office Action dated Sep. 29, 2011 for Application No. JP 2006-174158. |
Japanese Office Action dated Apr. 25, 2011 for Application No. JP 2006-174171. |
Japanese Office Action dated Jun. 8, 2012 for Application No. JP 2007-162956. |
Japanese Office Action dated Feb. 28, 2013 for Application No. JP 2007-162956. |
Korean Office Action dated Oct. 21, 2011 for Application No. KR 10-2005-0045990. |
Korean Office Action dated Dec. 18, 2012 for Application No. KR 10-2006-0056843. |
Korean Office Action dated Dec. 19, 2012 for Application No. KR 10-2006-0056844. |
Mexican Office Action dated Mar. 30, 2007 for Application No. PA/A/2004/005756. |
Mexican Office Action dated May 14, 2009 for Application No. PA/A/2006/007379. |
Mexican Office Action dated Nov. 20, 2009 for Application No. PA/A/2006/007379. |
Mexican Office Action dated Nov. 7, 2011 for Application No. PA/A/2005/005810. |
Mexican Office Action dated Oct. 16, 2009 for Application No. MX/A/2007/007468. |
Russian Office Action dated May 20, 2009 for Application No. RU 2005116666. |
Russian Office Action dated Apr. 28, 2010 for Application No. RU 2006122615. |
Singaporean Office Action dated Oct. 31, 2007 for Application No. SG 200604117-2. |
Number | Date | Country | |
---|---|---|---|
20110082426 A1 | Apr 2011 | US |
Number | Date | Country | |
---|---|---|---|
60478763 | Jun 2003 | US |
Number | Date | Country | |
---|---|---|---|
Parent | 10741875 | Dec 2003 | US |
Child | 12966236 | US |