Claims
- 1. A compound, including enantiomers, stereoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula I:
- 2. The compound claim 1, wherein m is 0 and n is 1.
- 3. The compound of claim 1, wherein R1 is
- 4. The compound of claim 1, wherein R1 is:
- 5. The compound of claim 1, wherein R2 is —(CH2)pNHC(═NH)NH2, where p is as defined in claim 1.
- 6. The compound of claim 1, wherein R2 is —(CH2)p—R4 where p and R4 are as defined in claim 1.
- 7. The compound of claim 1, wherein R2 is —(CH2)q—Ar1, wherein Ar1 is:
- 8. The compound of claim 1, wherein R2 is —(CH2)q—Ar1, wherein Ar1 is:
- 9. The compound of claim 1, wherein R2 is —(CH2)q—Ar1, wherein Ar1 is:
- 10. The compound of claim 1 wherein the moiety:
- 11. The compound of claim 1 wherein the moiety:
- 12. A pharmaceutical composition comprising as an active ingredient a compound of claim 1.
- 13. A compound, including enantiomers, stercoisomers and tautomers thereof, as well as pharmaceutically acceptable salts or solvates of said compound, said compound having the general structure shown in Formula II:
- 14. The compound of claim 13, wherein X is:
- 15. The compound of claim 13, wherein X is:
- 16. The compound of claim 13, wherein R1 is H.
- 17. The compound of claim 13, wherein R1 is a straight chain C1-C6 alkyl or a branched C1-C6 alkyl.
- 18. The compound of claim 13, wherein R1 is —(CH2)p—Ar1, where p and Ar1 are as defined in claim 13.
- 19. The compound of claim 13, wherein R1 is —(CH2)p—R4, where p and R4 are as defined in claim 13.
- 20. The compound of claim 13, wherein R2 is:
- 21. The compound of claim 13, wherein R2 is:
- 22. The compound of claim 13, wherein R2 is:
- 23. The compound of claim 13, wherein R2 is:
- 24. The compound of claim 13, wherein R2 is:
- 25. The compound of claim 13, wherein R2 is:
- 26. The compound of claim 13, wherein R3 is —(CH2)q—Ar2, where q and Ar2 are as defined.
- 27. The compound of claim 13, wherein R3 is —(CH═CH)-Phenyl.
- 28. The compound of claim 13, wherein Y is:
- 29. The compound of claim 13, wherein Y is:
- 30. The compound of claim 13, wherein Y is:
- 31. The compound of claim 13, wherein R1 is isopropyl or isobutyl.
- 32. A pharmaceutical composition comprising as an active ingredient a compound of claim 13.
Priority Claims (1)
Number |
Date |
Country |
Kind |
0127615.3 |
Nov 2001 |
GB |
|
Parent Case Info
[0001] This application claims the benefit of U.S. Provisional Application No. 60/304,020, filed Jul. 09, 2001.
Provisional Applications (1)
|
Number |
Date |
Country |
|
60304020 |
Jul 2001 |
US |