Franklin et al, Chemical Abstract, vol. 115, No. 21, Abstract 222, 779, &, p. 21, Nov. 25, 1991. |
Majamaa et al., "The 2-oxoglutarate Binding Site of Prolyl 4-Hydroxylase", Eur. J. Biochem, 138:239-245 (1984). |
Cunliffe et al., "Novel Inhibitors of Prolyl 4-Hydroxylase. 3..sup.1 Inhibition by the Substrate Analogue N-Oxaloglycine and Its Derivatives", J. Med. Chem. 35:2652-2658 (1992). |
Jolles et al., "Pristinamycine. Synthese de L'heptapeptide Lineair et D'oligopeptides Correspondant au Constituant I .sub..LAMBDA. de la Pristinamycine", Bull. Soc. Chim, FR. 8:2252-2259 (1965). |
English translation of Abstract of French article: Pristinamycine. Synthese de L'heptapeptide Lineaire et D'oligopeptides Correspondant au Constituant 1.sub..LAMBDA. de la Pristinamycine, 1965. |
Franklin et al., "Approaches to the Design of Anti-Fibrotic Drugs," Biochem. Soc. Trans., 19:812-815 (1991). |
T.J. Franklin, "Therapeutic Approaches to Organ Fibrosis", Int. J. Biochem, Cell. Biol. 29(1):79-89 (1997). |
Greene et al., "Protective Groups in Organic Synthesis", Chapters 2 and 3, pp. 10-174 (1991). |
Suzuki et al., "A Facile Synthesis of 1-Oxo-1,2-dihydroisoquinoline-3-carboxylate and 2-Pyridone-6-carboxylate Derivatives", Synthesis 461-462 (1978). |
Nunami et al., "Reaction of Phthalic Anhydrides with Methyl Isocyanoacetate: A Useful Synthesis of 1,2-Dihydro-1-oxoisoquinolines.sup.1 ", Chem. Pharm. Bull. 27(6):1373-1377 (1979). |
Caswell et al., "A Study of the Hydroxy- and Methoxyphthalimidoacetic Acids and the Methyl Methoxy-phthalimidoacetates (1,2)" J. Heterocycl. Chem. 3:328-332 (1966). |
Fowler et al., "Cyclic Imides. IX. Displacement of Halide From N-Substituted 3-Halophthalimides by Methoxide Ion (1.2)", 10:407-408 (1973). |
Kivirikko et al., "Modifications to a Specific Assay for Hydroxyproline in Urine", Anal. Biochem. 19:249-255 (1967). |
Kaule et al., "Assay for 2-Oxoglurate Decarboxylating Enzymes Based on the Determination of [1-.sup.14 c] Succinate: Application to Prolyl 4-Hydroxylase", Anal. Biochem. 184:291-297 (1990). |
Ryoo et al., "Studies on Plasma Protein Synthesis With a New Liver Perfusion Apparatus", P.S.E.B.M., 128:760-772 (1968). |
Tuderman et al., "An Affinity-Column Procedure Using Poly(L-proline) for the Purification of Prolyl Hydroxylase", Eur. J. Biochem., 52:9-16 (1975). |
Kedersha et al., "An Improved Method for the Purification of Vertebrate Prolyl Hydroxylase by Affinity Chromatography", Collagen Rel. Res., 1:345-353 (1981). |
M. Chojkier, "Hepatocyte Collagen Production In Vivo in Normal Rats,"J. Clin. Invest., 78:333-339, 1986. |
Ogata et al., "Minor Contribution of Hepatocytes to Collagen Production in Normal and Early Fibrotic Rat Livers", Hepatology 14(2):361-367 (1991). |
Blomhoff et al., "Isolation and Cultivation of Rat Liver Stellate Cells" Methods Enzymol., 90(6):58-71, 1990. |
Chojkier et al., "A New Method for Determining the Extent of Proline Hydroxylation by Measuring the Ratio of [4-.sup.3 H]:[.sup.14 C]Proline in Collagenase Digests", Anal. Biochem., 108:385-393 (1980). |
H. Schimassek, "Metabolite des Kohlenhydratstoffwechsels der Isoliert Perfundierten Rattenleber", H. Biochemin. Z. 336:460-467 (1963). |
English translation of Abstract of German article: "Metabolite des Kohlenhydratsoffwechsels der Isoliert Perfundierten Rattenleber". |
C. Rouiller, "Experimental Toxic Injury of the Liver", THE LIVER, vol. 2, pp. 335-476 (1964), New York, Academic Press, New York. |
Caswell et al., "Cyclic Imides. VII. Carboxyphthalimidoacetic Acids (1.2)", J. Heterocycl. Chem. 865-867 (1968). |
English Derwent Abstract of EP 0 650 961, 1995. |
European Search Report dated May 20, 1999. |
English Derwent Abstract of EP 0 548 883, 1993. |