Claims
- 1. A phenylacetic acid amide compound of the formula ##STR14## in which R.sub.1 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.2 is hydrogen, lower alkyl, lower alkoxy, halogen having an atomic number of not more than 35 or trifluoromethyl, R.sub.3 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35 and R.sub.4 is hydrogen, lower alkyl, lower alkoxy or halogen having an atomic number of not more than 35, R.sub.5 is lower alkylene or lower alkylidene, R.sub.6 is phenyl which is unsubstituted or substituted by lower alkyl, lower alkoxy, hydroxy and/or halogen, R.sub.7 is hydrogen, and the group --C(.dbd.O)--R.sub.8 is carboxyl or lower alkoxycarbonyl, or a therapeutically acceptable salt thereof.
- 2. A compound according to claim 1, wherein --R.sub.5 (R.sub.6)-- is phenyl-lower alkylidene which is unsubstituted or substituted by hydroxyl or is phenyl-lower alkylene, or a therapeutically acceptable salt thereof.
- 3. A compound according to claim 1 which is D-(-)-N-[[2-(2,6-dichlorophenyl-amino)-phenyl]-acetyl]-phenylglycine or a therapeutically acceptable salt thereof.
- 4. A compound according to claim 1 which is the methyl ester of DL-N-[[2-(2,6-dichlorophenyl-amino)-phenyl]acetyl]-phenylalanine.
- 5. A compound according to claim 1 which is DL-N[[2-(2,6-dichlorophenyl-amino)-phenyl]-acetyl]-phenylalanine or a therapeutically acceptable salt thereof.
- 6. A compound according to claim 1, which is the methyl ester of D-(-)-N-[[2-(2,6-dichlorophenyl-amino)-phenyl]-acetyl]-phenylglycine.
- 7. A pharmaceutical preparation containing an antiinflammatory effective amount of a compound as claimed in claim 1 together with conventional pharmaceutical excipients.
Priority Claims (2)
Number |
Date |
Country |
Kind |
77316 |
May 1977 |
LUX |
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78106 |
Sep 1977 |
LUX |
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CROSS REFERENCE
This is a division of application Ser. No. 033,295 filed on Apr. 25, 1979, now U.S. Pat. No. 4,250,192, which is a continuation of our copending applications Ser. No. 905,087, filed May 11, 1978 now abandoned and Ser. No. 906,292, filed May 15, 1978 now abandoned.
US Referenced Citations (3)
Number |
Name |
Date |
Kind |
3536758 |
Sallmann et al. |
Oct 1970 |
|
3652762 |
Sallmann |
Mar 1972 |
|
3897782 |
Boltze et al. |
Jul 1975 |
|
Related Publications (1)
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Number |
Date |
Country |
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906292 |
May 1978 |
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Divisions (1)
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Number |
Date |
Country |
Parent |
33295 |
Apr 1979 |
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Continuations (1)
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Number |
Date |
Country |
Parent |
905087 |
May 1978 |
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