This application is based on and hereby claims priority to German Application No. 103 41 092.9 filed on 5 Sep. 2003, the contents of which are hereby incorporated by reference.
1. Field of the Invention
An aspect of the invention relates to a system for at least one of contactless moving and fixing, i.e., holding in position, a magnetic body in a three-dimensional working space that is surrounded by surfaces defined in a rectangular x,y,z coordinate system, using a magnet coil system which surrounds the working space.
2. Description of the Related Art
Use is made in medicine of endoscopes and catheters that are introduced via incisions or body orifices, and can be displaced in a longitudinal direction from outside and can thus be navigated only in one dimension. Light guides permit optical inspection, it being possible to use control wires to rotate an endoscope pipe and thus the viewing direction. It is possible thereby to construct devices for biopsies, in particular. However, the probes used in this case can be navigated only in limited fashion, particularly at branching points, and so contactless exertion of force from outside could be attended by an expansion of the field of application.
The publication “IEEE Transactions on Magnetics”, Vol. 32, No. 2, March 1996, pages 320 to 328 and U.S. Pat. No. 5,125,888 A disclose a magnet coil system for contactless magnetic control of a probe including six preferably superconducting individual coils which are arranged on the faces of a cube whose position is to be described mathematically in a rectangular x,y,z coordinate system. The aim of these coils is to produce variable field directions and field gradients, in order to guide and to move a catheter with magnetic material or magnetic implants for therapeutic purposes in a body, for example a human body, to be examined. However, it is not possible to achieve unrestricted navigational freedom of the magnetic body with the aid of a magnet coil system composed of six individual coils.
U.S. Pat. No. 6,241,671 B1 describes a magnet coil system having three coils, while U.S. Pat. No. 6,529,751 B2 describes an arrangement of a few permanent magnets that are arranged rotatably about a patient and whose field can be influenced by magnetic diaphragms, and which can produce a magnetic wave for moving a magnetic probe.
Also known, furthermore, are magnet coil systems having rotatable permanent magnets for controlling magnetic catheters, in particular with radiographic monitoring.
This related art does not address methods for stabilizing position by feedback; it is assumed that in a manner prescribed by field direction and gradient a magnetic probe body always bears against an inner surface inside a body to be examined.
WO 96/03795 A1 describes a method having additional pulse coils with the aid of which a magnetic probe is to be moved in a stepwise fashion by accurately defined current pulses under computer control.
So called video capsules that serve for inspecting the digestive tract are also known, for example, from the Journal “Gatrointestinal Endoscopy”, Vol. 54, No. 1, pages 79 to 83. In this case, the video capsule is moved by the natural intestinal movement; that is to say the movements and viewing direction are entirely random.
DE 101 42 253 C1 describes a corresponding video capsule that is equipped with a bar magnet and with video and other intervention devices. An external magnet coil system is intended to exert forces on the bar magnet for the purpose of navigation. Mention is made of a freely suspended, so-called helicopter mode with external control by a 6D mouse, a feedback of the force via the mouse, and a positional feedback by a transponder. No details emerge from the document as regards the implementation of the corresponding magnet coil system and the operation of its individual coils.
None of the systems mentioned above allows a magnetic body to be held in a free-floating manner at a predetermined point with the aid of magnetic fields. This is because, according to Earnshaw's Theorem (see “Transactions of the Cambridge Philosophical Society”, Vol. 7, 1842, pages 97 to 120), any such configuration is unstable in at least one spatial direction. This means that the magnetic body always rests on an inner surface in the working space, predetermined by the local field gradients, or it bends a wire-guided catheter in a desired direction.
An aspect of the present invention is to specify a system by which a (ferro)magnetic body such as a bar magnet can be navigated and can be fixed in a stable contactless manner in accordance with the abovementioned DE-C1 document, that is to say with the body being aligned and with force being exerted on it, using a special magnet coil system which surrounds the working space. The alignment and the magnitude and direction of the force on the body are intended in this case to be prescribable from outside magnetically and without mechanical connection.
Another aspect of the invention is to serve the contactless movement and/or fixing of a magnetic body in a three-dimensional working space that is surrounded by surfaces defined in a rectangular x,y,z coordinate system. The system is in this case intended to contain the following parts, specifically
It is assumed in the case of the magnet coil system to be used, surrounding the working space like a cage and thereby permitting access in the z direction, that the conditions rotH=0 and divB=0 imposed by the Maxwell equations—with the variables in bold in each case symbolizing vectors—always produce field gradients in pairs. It was found that of the three possible field components Bx, By and Bz of the possible nine field gradients dBx/dx, dBx/dy, dBz/dz, dBy/dx, dBy/dy, dBy/dz, dBz/dx, dBz/dy and dBz/dz only five independent gradients are produced. In this case, it is then necessary for eight different current patterns corresponding to the magnetic degrees of freedom to be capable of being impressed on the fourteen individual coils, with currents of the same magnitude. These current patterns each predominantly produce a field component or a field gradient. It is then possible by superposition to produce any combination of magnetic field components and field gradients that is permitted by the Maxwell equations.
This allows a contactless alignment, which can be predetermined as required (=navigation including fixing) and a magnetic force on a magnetic body, for example a probe such as a catheter, endoscope or a video capsule which is connected to a magnetic element, in accordance with DE 101 42 253 C1, by magnetic fields in a working space.
The system according to the invention advantageously makes it possible to ensure interaction of position control for the magnetic body in the three spatial directions with the complex requirements for the field configuration, as is produced by the abovementioned magnet coil arrangement. Whenever the magnetic body is moved or rotated, the currents in this case change in all fourteen individual coils. The coil currents in the individual coils are in this case set such that the error between the set position and the actual position is reduced, in particular being minimized. The components used for setting and processing are designed appropriately.
Furthermore, the refinement with force feedback to the device for setting the orientation, set position and movement direction, as well as possible limiting of the speed at which the magnetic body is moved are advantageous. In particular, this allows free, stable floating (as is desirable for medical diagnosis) in a working space, for example of a video capsule which is equipped with a magnetic body in the form of a ferromagnet or permanent magnet, in accordance with the cited DE 101 42 253 C1, in a sample by active position control.
Thus, the fourteen individually drivable individual coils can be arranged on surfaces situated opposite in pairs, and on at least one tubular peripheral surface extending in the z direction. It is possible thereby for the surfaces to define a cuboid or cube except for the peripheral surface. However, they need not necessarily be planar. The individual coils situated on these surfaces then permit good access to the working space, in particular in the z direction.
It is advantageously possible in this case for at least six of the individual coils to be situated on the end-face or lateral surfaces, situated oppositely in pairs, of the working space, and to serve to produce the three magnetic field components Bx, By, Bz as well as the two diagonal elements of the gradient matrix. At the same time, at least four of the individual coils can be arranged distributed as seen in the circumferential direction on the at least one tubular peripheral surface surrounding the working space, and can serve to produce at least one nondiagonal element of the gradient matrix. The required three nondiagonal elements can be formed in this way together with the remaining individual coils.
In accordance with a particularly advantageous embodiment of the coil system, it is possible for
It is equally well possible instead of this to provide in the case of the coil system
In the embodiments described above, the field gradient coils situated on the (imaginary) peripheral surface can advantageously be fashioned in the form of a saddle. It is possible in this case for the end-face arcuate parts running on the peripheral surface in a circumferential direction to be situated next to one another as seen in this circumferential direction, that is to say to assume an angle of arc of >90° in each case, or else for them to overlap. It is easy to manufacture appropriate individual coils which produce clear field conditions.
Moreover, at least a few of the field component coils can be fashioned as flat rectangular coils or circular coils. In particular, the coils located at the end faces thus permit good access to the working space in the z direction.
Parts composed of soft magnetic material can advantageously be assigned on the outer side of the coil system for the purpose of field amplification and/or field shielding.
In order to drive the fourteen individual coils of the magnet coils, it is advantageous to use a computer to drive its respectively assigned power supply as a function of the respective position of the magnetic body to be moved.
These and other objects and advantages of the present invention will become more apparent and more readily appreciated from the following description of the preferred embodiments, taken in conjunction with the accompanying drawings of which:
a to 3h are schematic perspective views of the individual coils of the magnet coil system illustrated in
a to 6i are schematic perspective views of the current-conducting directions in the individual coils of the magnet coil system illustrated in
Reference will now be made in detail to the preferred embodiments of the present invention, examples of which are illustrated in the accompanying drawings, wherein like reference numerals refer to like elements throughout.
A system according to the invention can be used to move a magnetic test specimen in a contactless fashion in a working volume and to hold it steady. In this case, the alignment as well as the magnitude and direction of the forces on this test specimen can be prescribed from outside magnetically and without mechanical connection. Particularly in medical applications, it is possible thereby for a probe fitted with such a magnetic test specimen to be a catheter or an endoscope having magnet elements or a small television camera with an illumination system and transmitter that transmits video images from the interior of the body such as, for example, the digestive tract or the lung. Moreover, ferromagnetic foreign bodies such as, for example, a needle or functional modules can be moved by magnetic forces in objects or spaces inaccessible from outside, or be removed therefrom. In addition to being applied in medicine, an inventive system can also be equally well used in other fields such as, for example in contaminated spaces. Assigned magnetic probes can also be used to inspect, for example internally, other, in particular inaccessible objects, it also being possible, of course, for the probes to be fitted with another or additional range of functions.
The magnet coil system used can thus be used to control the test specimen from outside by magnetic forces in all three lateral degrees of freedom and in a viewing direction with two rotational degrees of freedom. Moreover, the magnet coil system in this case advantageously permits access from outside in the z direction, for example in order to position persons to be treated in the interior of the working space.
The magnet coil system 2 in
For active position control of the magnetic body 10, the system 2 may use conventional components for detection of the actual position of the body 10 in the working space A. By way of example, three position measurement devices 24x, 24y and 24z, may be used to determine the position of the body 10 in the respective coordinate directions. The corresponding measured values are supplied to a control device 25, which is part of means for setting a set position of the magnetic body. For this purpose, the control device has three control loops for the x, y and z positions, which allow an opposing force to be applied to the magnetic body 10 in the x, y and z directions from the control error between the actual position and the set position. The control device 25 is followed by a converter unit 26. This converter unit 26 controls fourteen power supply units PA1 to PA14, by which the currents I1 to I14 are produced in the fourteen individual coils of the magnet coil system 2. A defined field direction and magnetic force F=grad(m B) (where m is the vector of the magnetic moment in the body) are produced on the magnetic body 10 in the coil system. In this case, adjustment forces (which are derived from the position control) in the three coordinate directions are converted into magnetic fields and gradients as well as further coil currents, which exert these forces on the magnetic body. Errors in the set position are thus counteracted, and the position of the body is stabilized. During free floating, the weight force and any further forces which may occur are set as a consequence of this in order to overcome mechanical resistances. The polar angles/coordinates θ and φ of the orientation and/or the set position and/or the movement direction in the three spatial coordinates are predetermined by a device 27 for setting the orientation, set position and movement direction of the magnetic body 10, for example in the form of a joystick with a control column 27a, or a 6D mouse. To do this, the actuator 27 produces the set positions x, y and z and compares them in respectively associated comparators 30x, 30y and 30z with the actual position, which is obtained from the measurement signals from the position measurement devices 24x, 24y and 24z. The difference values are passed as control errors to the control device 25, where they are amplified, processed further in the control sense, and are supplied to the converter device 26, where current values for the fourteen coil power supply units PA1 to PA14 are calculated using mathematical methods from the values supplied in this way, by which changed field gradients and thus magnetic forces Fx, Fy and Fz are produced on the magnetic body 10. These forces counteract the control error of the body in its position x, y and z. Furthermore, the actuator 27 passes to the converter device 26 the set directions using polar angles θ and φ in space, which are converted there to the currents for the three field components Bx, By and Bz, and are passed appropriately to the coil system 2 via the power supply units PA1 to PA14.
The system 2 may advantageously also be designed such that the force (which is calculated in the converter device 26) on the magnetic body 10 exerts a proportional force effect on the joystick 27a of the device via actuating elements in the actuator 27. This allows, for example, undesirable magnetic resistance on the body 10 to be sensed by an operator of the actuator, for example an examining doctor.
In a further refinement of the system, the speed of the magnetic body 10 can advantageously be detected from a position measurement by differentiation, and can be fed into the control loop with the aim of limiting this speed. This makes it possible, for example, to prevent damage caused by the magnetic body striking walls, for example in the body interior of the sample 23.
Details of a typical exemplary embodiment of a magnet coil system 2 for a system 22 according to the invention are illustrated schematically in
The magnet coil system 2 includes fourteen normally conductive or superconducting individual coils that are preferably constructed as rectangular or saddle coils. In this case, the winding forms are illustrated merely schematically in
Let a line joining the elements dBx/dx, dBy/dy and dBz/dz be regarded in this case as the diagonal D on the gradient matrix. The gradient matrix is constructed symmetrically with reference to this diagonal D or to the abovementioned magnetic field gradients situated on it. In this case, the sum of the diagonal elements is equal to zero. In accordance with
The field gradient coils 6a to 6d and 7a and 7d fashioned in the form of saddles are used in each case to construct two coil arrangements 6 and 7 that are arranged in series as seen in the z direction. In terms of field, the saddle-shaped field gradient coils enclose the working space A, in which case they are arranged jointly on at least one imaginary tubular peripheral surface F6 with an axis running parallel to the z direction. Seen in a circumferential direction, the gradient coils belonging to a coil arrangement are mutually spaced; that is to say there is an interspace in each case between their end-face arcuate parts and thus between their longitudinal sides running in the z direction. However, it is also possible for neighboring gradient coils to overlap with their longitudinal sides. The imaginary peripheral surface F6 has a circular cross section, for example. However, it can also have another, for example square, cross-sectional shape. Also conceivable are concentric peripheral surfaces on which the individual coils from one or from both coil arrangements are located. Neither need the at least one peripheral surface F6 necessarily be situated inside the space enclosed by the field component coils 3a, 3b, 4a, 4b, 5a, 5b, but they can also enclose the structure made from these coils, if appropriate. In general, at least the field gradient coils belonging to a coil arrangement 6 and/or 7 are of the same form. In general, the surfaces which have been mentioned are imaginary surfaces. However, the individual coils (which extend on them) of the magnet coil system 2 are, of course, held by a physical fixing structure, not illustrated in the drawings.
With the aid of the field gradient coils 6a to 6d and 7a to 7d, the magnetic field gradients dBx/dy, dBz/dx and dBz/dy are to be constructed in accordance with
If an elongated magnetic body, for example a ferromagnet or permanent magnet, that is connected to a probe, for example, is now introduced into the working space A of the magnet coil system 2, it tends to be aligned parallel to the field direction, thereby also prescribing the alignment of the probe. The field gradients in this case exert a force F=grad(m·B) on the magnetic body, m being the vector of the magnetic moment of the magnetic body. By driving each of the fourteen individual coils in a targeted fashion, it is then possible to align the magnetic body arbitrarily in the working space A, and also to exert on it a prescribed force F in all directions, that is to say the body can not only be rotated, but also moved linearly.
a to 3h show in pairs the fourteen individual coils of a magnetic coil system, for example of the system 2 according to
In addition to the field components respectively desired, each current pattern also produces other field components in the magnet coil system. These other field components are a function of the respective coil measurements and of the location of the magnetic body; their amplitude increases from the center outward in the direction of the windings of the coils. That is to say, there is thus no simple relationship between the current intensity of the current pattern with the field direction and force direction F=grad(m·B) at a location of the magnetic body.
However, it is possible by suitably overlapping the eight current patterns in the fourteen individual coils to set at a location of the magnetic body (probe location) precisely those fields and field gradients that produce the desired alignment and action of force on the magnetic body. It is possible with particular advantage, for example, to implement free suspension of the magnetic body in the space precisely when the weight force F=m g=grad(m·B) is produced (M=mass, g=acceleration due to gravity). The calculation in this regard is advantageously performed using a computer that, in particular, carries out the following computations and, if appropriate, repeats them continuously during a movement of the magnetic body:
A schematic illustration of a device for driving the fourteen individual coils in cooperation with an imaging device for monitoring the position of the magnetic body or probe is provided in
The following measures can be provided for the purpose of a specific configuration of the magnet coil system in accordance with the illustrations in the drawings:
In the case of the exemplary embodiments, illustrated in the above drawings, of the inventive magnetic coil system 2, it has been assumed that in addition to the field components Bx, By and Bz the field component coils arranged orthogonally in pairs on opposite faces of a cube can also be used to produce two of the three diagonal field gradients in accordance with the above gradient matrix. However, it is possible, furthermore, also to use field component coils to generate nondiagonal field gradients. It is necessary for this purpose that two of the three field component coils are formed by coil pairs composed of individual coils. Such an embodiment can be provided, in particular, whenever the magnet coil system has a squarer contour around a working space. A corresponding exemplary embodiment of a magnet coil system having, in turn, fourteen individual coils is indicated in
The invention has been described in detail with particular reference to preferred embodiments thereof and examples, but it will be understood that variations and modifications can be effected within the spirit and scope of the invention covered by the claims which may include the phrase “at least one of A, B and C” as an alternative expression that means one or more of A, B and C may be used, contrary to the holding in Superguide v. DIRECTV, 69 USPQ2d 1865 (Fed. Cir. 2004).
Number | Date | Country | Kind |
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10341092.9 | Sep 2003 | DE | national |