This application claims priority under 35 U.S.C. § 119 to European Patent Application No. 20151338.9, filed Jan. 13, 2020, the entire contents of which are hereby incorporated by reference.
The present disclosure generally relates to surgical navigation, namely to a computer-implemented method for controlling a navigation view for surgical navigation. A processor, a computer-readable medium and a data carrier signal are also disclosed.
During surgical navigation, a surgeon may use a surgical navigation system to help align a surgical instrument relative to a patient. To this end, positions and orientations of surgical objects, such as the surgical instrument and the patient, can be determined as a basis for providing navigation instructions to the surgeon.
In an exemplary application of a surgical navigation system, the surgical instrument and the patient are each associated with a tracking marker, wherein three dimensional image data of the patient previously obtained by, for example, a computer tomography (CT) scan is registered with the patient tracking marker and the surgical instrument is registered with the instrument tracking marker. By tracking the tracking markers of the patient and the surgical instrument, the position and orientation of both the patient and the surgical instrument, and thus a spatial relationship between the three dimensional image data of the patient and the position and orientation of the surgical instrument can be determined.
In several surgical procedures surgeons need to align a surgical instrument such as a shunt stylet, drill, awl, tap, screw-driver, biopsy needle, etc., relative to the patient's body free-handedly, in order to align the surgical instrument with a pre-operatively planned trajectory. A pre-operatively planned trajectory (i.e., planned trajectory) is typically defined by a planned entry point and a planned target. The entry point typically defines a point where an incision shall be made on the skin of the patient's body or where an opening shall be drilled in the patient's skull, and through which the surgical instrument shall enter the patient's body. The entry point can define the point on the bony surface of a vertebra where an implant such as a pedicle screw shall be inserted. The target and the planned entry point can be defined in the three dimensional image data of the patient. Examples of such targets are a target point (i.e., a point in ventricles), a tumor, an anatomical organ to be treated, desired tip position of a pedicle screw and more. The target may be defined by defining a point or outlining a geometry in the three dimensional image data.
After determining planning data describing the planned entry point and the target, surgical navigation may be performed during which the aforementioned determined spatial relationship is, for example, displayed on a screen in form of a navigation view, helping the surgeon guide the surgical instrument relative to the patient.
In some cases, the surgeon may decide during surgical navigation that a slightly different entry point compared with the planned entry point is preferable. In other cases, the surgeon may not be able to perfectly align the surgical instrument to the planned entry point.
Some navigation views may support two different alignment modes. In a first alignment mode, the surgical instrument is aligned with both the planned entry point and the planned trajectory. If the trajectory is perfectly aligned, the outcome equals that shown in
The prior art does not provide a fast and accurate alignment of navigated surgical instruments in order to accurately and reliably reach a planned target.
There is a need for a computer-implemented method of controlling display of a navigation view that solves one or more of the aforementioned or other problems. According to a first aspect, a computer-implemented method of controlling display of a navigation view for surgical navigation is provided. The method comprises obtaining planning data defining a planned entry point and a planned target, wherein the planned entry point and the planned target are defined in a coordinate system of a computer model of at least one anatomical element. The method further comprises obtaining tracking data describing a current pose of a surgical instrument in the coordinate system and determining, based on at least the tracking data, a current entry point lying on a trajectory having a fixed spatial relationship with the surgical instrument. The method further comprises controlling display of a navigation view visualizing at least a recommended entry point, wherein the recommended entry point is instantaneously changed from the planned entry point to the current entry point, upon a distance between the planned entry point and the current entry point fulfilling a predefined condition.
The planned entry point for example fulfills at least one condition chosen from being distant from the planned target, being not comprised in the planned target and being not identical to the planned target. The planned entry point may lie on, a predetermined distance below or a predetermined distance above an outer surface of the computer model of the at least one anatomical element, for example in case the computer model is determined based on computer tomography, CT, patient image data. In one example, the planned entry point lies on the outer surface of the computer model, whilst the planned target lies beneath the outer surface of the computer model. The outer surface may correspond to a bony surface of the anatomical element.
The at least one anatomical element is for example an anatomical organ, a bone, a limb or else. In one example, the at least one anatomical element comprises all body parts within a section of or within the whole patient's body. The section may be limited in size depending on the imaging technology used. In other words, the at least one anatomical element may comprise all anatomical elements described by patient image data. The patient image data is for example obtained by medical image acquisition of the patient and may in particular be CT patient image data or magnetic resonance, MR, patient image data. The at least one anatomical element may essentially consist of a certain tissue type such as bone, muscle, skin or tendon. For example, the at least one anatomical element has a predetermined transparency for X-rays, resulting in a predetermined range of Hounsfield values in X-ray or CT images.
The planned target for example is equal to or comprises a target point or an outline of an extended anatomical target. The planned target may be a volume in the computer model, for example a volume comprising or describing an anatomical element such as an anatomical organ, a tumor, a region of interest or else.
The planning data may be obtained by obtaining first data describing the planned entry point and obtaining second data describing the target. The orientation of the surgical instrument in the coordinate system may be obtained by obtaining an orientation of the surgical instrument in a tracking coordinate system and transforming this orientation into the coordinate system based on a known transformation between the tracking coordinate system and the coordinate system.
The trajectory is for example (i.e., essentially) parallel to a longitudinal axis of the surgical instrument, (i.e., essentially) parallel to an insertion direction of the surgical instrument or (i.e., essentially) orthogonal to a handle of the surgical instrument.
The navigation view for example visualizes the recommended entry point by aligning or orienting the navigation view with respect to the recommended entry point.
The predefined condition is for example that the distance between the planned entry point and the current entry point is lower than a threshold. The threshold may be a predetermined value such as for example 0.5 mm, 1 mm, 1.5 mm, 3 mm or 4 mm, in particular 2 mm. The threshold in one example is larger than 0 mm, in particular larger than 1 mm or larger than 2 mm. The threshold may be obtained in a previous method step. The threshold may be set by a user. For example, the threshold is a value depending on a spatial relationship between the planned entry point and the target. In this case, the threshold may correspond to a certain percentage of the distance between the planned entry point and the target. The threshold is for example a value depending on a spatial relationship between the surgical instrument and at least one of the target, the current entry point and the planned entry point.
The threshold may be chosen such that the instantaneous change of the recommended entry point can be detected by a user solely from the navigation view. The threshold may be larger than a distance described by a single pixel of the navigation view. For example, the threshold is larger than a predetermined percentage of a width of a shaft of the surgical instrument.
The navigation view may visualize the recommended entry point and the planned target. The navigation view for example visualizes the recommended entry point and the planned target by displaying the recommended entry point and the target on a representation of the computer model and/or by orienting the navigation view with respect to at least one of the recommended entry point and the target.
The navigation view in one example has a viewing direction corresponding to a straight line between the recommended entry point and the planned target.
The navigation view may be a bullseye view centered on a straight line between the recommended entry point and the planned target. In another variant, the navigation view comprises a bullseye centered on the straight line between the recommended entry point and the planned target. The bullseye or the bullseye view may comprise at least one concentric line centered on the straight line between the recommended entry point and the planned target. The at least one concentric line may be a two-dimensional line lying in a plane, which plane is orthogonal to the straight line between the recommended entry point and the planned target. The bullseye or the bullseye view for example has the straight line between the recommended entry point and the planned target as a viewing direction. In addition, or as an alternative, to the bullseye, the navigation view may comprise one or more crosshairs, for example a first crosshair essentially orthogonal to a second crosshair. The one or more crosshairs may intersect the straight line between the recommended entry point and the planned target.
The navigation view in one variant comprises a visualization of a relative spatial relationship between the recommended entry point and the planned target. The visualization of the relative spatial relationship between the recommended entry point and the planned target is for example is at least one of a number, a text, a bar diagram, a progress bar or else.
For example, the navigation view comprises a visualization of a relative spatial relationship between the surgical instrument and at least one destination chosen from the recommended entry point and the planned target. For example, the navigation view comprises a visualization of a shortest distance between the trajectory and the planned target. The visualization of the relative spatial relationship between the surgical instrument and the at least one destination is for example at least one of a number, a text, a bar diagram, a progress bar or else.
The navigation view may comprise a visualization of a relationship between a distance between a position of the surgical instrument in the coordinate system and the recommended entry point and a distance between the recommended entry point and the target. The navigation view may comprise a visualization of a relationship between a first distance and a second distance, wherein the first distance is for example a distance between a position of the surgical instrument in the coordinate system and one of the recommended entry point and the target, and the second distance is for example a distance between the recommended entry point and the target. The navigation view in one example comprises a visualization of a fraction determined by dividing the first distance by the second distance. The navigation view may comprise a visualization of a fraction determined by dividing the second distance by the first distance. In another example, the navigation view comprises a visualization of at least one distance chosen from the first distance and the second distance.
The visualization of the relative spatial relationship, the visualization of the relationship and/or the visualization of the fraction is for example a progress bar. The progress bar may be concentrically formed around an alignment point in the navigation view. The alignment point in one example lies on a straight line between the recommended entry point and the planned target. The alignment point may be the center of the bullseye and/or the crosshairs.
In one variant, the recommended entry point is permanently changed from the planned entry point to the current entry point, upon the distance between the planned entry point and the current entry point fulfilling the predefined condition.
In another variant, the recommended entry point is instantaneously reset from the current entry point to the planned entry point, upon the distance between the planned entry point and the current entry point no longer fulfilling a predefined criterion. The predefined criterion is for example the predefined condition. In one example, the predefined criterion is that the distance between the planned entry point and the current entry point is lower than a limit value. The limit value defined by the predefined criterion may be larger than the threshold defined by the predefined condition. The limit value may be a predetermined value such as for example 0.5 mm, 1 mm, 1.5 mm, 2 mm, 2.5 mm or 3 mm. The limit value in one example is larger than 0 mm. The limit value may be obtained in a previous method step. The limit value may be set by a user. For example, the limit value is a value depending on a spatial relationship between the planned entry point and the target. In this case, the limit value may correspond to a certain percentage of the distance between the planned entry point and the target. The limit value is for example a value depending on a spatial relationship between the surgical instrument and at least one of the target, the current entry point and the planned entry point. The limit value may be chosen such that the instantaneous reset of the recommended entry point can be detected by a user solely from the navigation view. The limit value may be larger than a distance described by a single pixel of the navigation view. For example, the limit value is larger than a predetermined percentage of a width of a shaft of the surgical instrument.
According to a second aspect, a processor for a surgical navigation system is provided. The processor is configured to obtain planning data defining a planned entry point and a planned target, wherein the planned entry point and the planned target are defined in a coordinate system of a computer model of at least one anatomical element. The processor is further configured to obtain tracking data describing a current pose of a surgical instrument in the coordinate system and to determine, based on at least the tracking data, a current entry point lying on a trajectory having a fixed spatial relationship with the surgical instrument. The processor is configured to control display of a navigation view visualizing at least a recommended entry point, wherein the recommended entry point is instantaneously changed from the planned entry point to the current entry point, upon a distance between the planned entry point and the current entry point fulfilling a predefined condition.
According to a third aspect, a computer-readable medium is provided. The computer-readable medium comprises a computer program, the computer program comprising instructions which, when the program is executed by a processor, cause the processor to carry out the method of the first aspect. For example, the computer program comprises instructions which, when the program is executed by a processor, cause the processor to obtain planning data defining a planned entry point and a planned target, wherein the planned entry point and the planned target are defined in a coordinate system of a computer model of at least one anatomical element, obtain tracking data describing a current pose of a surgical instrument in the coordinate system, determine, based on at least the tracking data, a current entry point lying on a trajectory having a fixed spatial relationship with the surgical instrument, and control display of a navigation view visualizing at least a recommended entry point, wherein the recommended entry point is instantaneously changed from the planned entry point to the current entry point, upon a distance between the planned entry point and the current entry point fulfilling a predefined condition.
According to a fourth aspect, a data carrier signal is provided. The data carrier signal carries information which represent a computer program, the computer program comprising instructions which, when the program is executed by a processor, cause the processor to carry out the method of the first aspect.
Further details, advantages and aspects of the present disclosure will become apparent from the following embodiments taken in conjunction with the drawings wherein:
In the following description, exemplary embodiments of a computer-implemented method, a processor, a computer-readable medium and a data carried signal will be explained with reference to the drawings. The same reference numerals will be used to denote the same or similar structural features or method steps.
The surgical instrument 18 comprises a handle 20 and a shaft 22 having a longitudinal axis 24 that coincides with an insertion direction of the surgical instrument or with an insertion direction of a tool to be inserted through the shaft 22 of the surgical instrument 18.
The surgical navigation system 100 further comprises an electromagnetic tracking system 26 comprising a field generator 28 and a position determining unit 30. The position determining unit 30 is configured to determine a position of an electromagnetic sensor with respect to the field generator 28 in a second tracking coordinate system 32. For example, and electromagnetic tracker 34 is attached to the patient 14 and an additional electromagnetic sensor is attached to the surgical instrument 18 (not shown). The position determining unit 30 may be comprised in or realized by the processor 2. It is noted that the surgical navigation system 100 may comprise only one, or may comprise both of the optical tracking system 6 and the electromagnetic tracking system 26.
Patient image data 36 in an image data coordinate system 38 may be stored in a storage unit (not shown) and/or obtained by the processor 2. A computer model of at least one anatomical element may be determined based on the patient image data 36 by the processor 2, for example in the image data coordinate system 38. A registration can be performed in order to derive a transformation between a position and orientation of the optical tracker 12 and the image data coordinate system 38. Alternatively or additionally, a registration may be performed in order to derive a transformation between a position and orientation of the electromagnetic tracker 34 and the image data coordinate system 38. This enables the processor 2 to determine a correlation of the patient image data 36 with a current position and orientation of the patient 14. The surgical instrument 18 can be tracked as well in order to enable determining and displaying a navigation view indicating a relative spatial relationship between the surgical instrument 18 and the patient 14.
The navigation view may show a representation of the computer model, which was registered relative to the patient 14, and a representation of the surgical instrument 18. The determination of the navigation view and the controlling of the navigation view to be displayed on the display 4 may be performed by the processor 2. The navigation view is configured to help a surgeon during surgical navigation.
The method comprises a step 40 of obtaining planning data. The planning data describes a planned entry point in a coordinate system of the computer model of the at least one anatomical element. The planned entry point for example lies on an outer surface of a computer model of a patient body. The patient body is the body of the patient 14. The outer surface of the computer model of the at least one anatomical element may represent a bony surface of the at least one anatomical element. The planning data further describes a planned target in the coordinate system of the computer model. The planned target for example lies beneath the outer surface of the computer model. The planned target may be an anatomical element comprised in the patient body and identified in the patient image data 36.
The planned target may comprise or be identical to a planned target point. The coordinate system of the computer model is in one example identical with the image data coordinate system 38.
The method comprises a further step 42 of obtaining tracking data. The tracking data describes a current pose of the surgical instrument 18 in the coordinate system. The current pose comprises at least one of a current position, also referred to as corresponding position, and a current orientation, also referred to as corresponding orientation, of the surgical instrument 18. The current orientation describes an alignment of the surgical instrument 18 in the coordinate system, for example three dimensional coordinates of the axis 24. The current position of the surgical instrument 18 may be described by a point on the axis 24 or by three-dimensional coordinates in the coordinate system.
In case the optical tracking system 6 determines the pose of the surgical instrument 18 by tracking the optical tracker 16 in the first tracking coordinate system 10, a known transformation between the first tracking coordinate system 10 and the coordinate system can be used in order to determine the current pose of the surgical instrument 18 in the coordinate system. This known transformation may be obtained by performing a registration as mentioned above.
In addition or alternatively to the optical tracking system 6 tracking the patient 14, the electromagnetic tracking system 26 may be used for this purpose. In case the electromagnetic tracking system 26 determines the pose of the surgical instrument 18 by tracking the electromagnetic tracker 34 in the second tracking coordinate system 32, a known transformation between the second tracking coordinate system 32 and the coordinate system can be used in order to determine the current pose of the surgical instrument 18 in the coordinate system. This known transformation may be obtained by performing a registration as mentioned above. In the following, all described (i.e., relative) positions and orientations are meant to be (i.e., relative) positions and orientations in the coordinate system. It is apparent that the (i.e., relative) positions and orientations may alternatively be described in a different coordinate system and that a transformation can be used to transform the coordinate system into the different coordinate system.
The method comprises a step 44 of determining, based on the tracking data, the current entry point. The current entry point is an approximation of where the surgical instrument will enter the at least one anatomical element, in case it is being inserted into the at least one anatomical element starting from the current pose. The current entry point lies on a trajectory having a fixed spatial relationship with the surgical instrument 18.
The current entry point in one example lies on a distal (front) tip of the surgical instrument. In this case, the trajectory does not necessarily need to be determined and the tracking data may only describe a position of the surgical instrument 18 in the current pose. In addition or alternatively thereto, the current entry point may lie on the outer surface of the computer model. In addition or alternatively thereto, the current entry point may be the point on the trajectory of the surgical instrument which is closest to the planned entry point.
In case the current entry point lies remote from the surgical instrument, the method may comprise determining trajectory data describing the trajectory of the surgical instrument 18. The trajectory is for example determined based on the tracking data describing at least an orientation of the surgical instrument 18 in the current pose. The trajectory is a straight line defined in the coordinate system and has a fixed spatial relationship with the surgical instrument 18. According to one example, the trajectory is parallel with or coincides with the longitudinal axis 24 of the surgical instrument 18. Further data may be taken into account for determining the trajectory data, for example geometry data describing the fixed spatial relationship.
The method also comprises a step 46 of controlling display of a navigation view. The navigation view visualizes at least a recommended entry point. For example, the navigation view visualizes the recommended entry point by being a view aligned or oriented with respect to the recommended entry point. A viewing direction of the navigation view may be determined based on the recommended entry point, so that the navigation view visualizes the recommended entry point. The navigation view may further visualize the planned target. In one example, the navigation view is a bullseye view centered on a straight line between the recommended entry point and the planned target and having a straight line between the recommended entry point and the target as a viewing direction. In a different example, the navigation view shows a perspective view of the three dimensional computer model of the at least one anatomical element comprised in the body of the patient 14, in which view the recommended entry point is highlighted.
The recommended entry point is instantaneously changed from the planned entry point to a current entry point lying on the trajectory, upon a distance between the planned entry point and the current entry point fulfilling a predefined condition. The predefined condition is for example that the distance between the planned entry point and the current entry point is lower than a threshold. The threshold may be a predetermined value above 0 mm below 5 mm, such as 2 mm. For example, the threshold is a value depending on a spatial relationship between the planned target point and the target. In this case, the threshold may correspond to a certain percentage of the distance between the planned target point and the target. In the following, details of the method of
Preferably, the perspective view shown in
The navigation view in this example is a bullseye view having a straight line extending between the planned entry point 48 and the planned target point 52 as a viewing direction. The navigation view in this example comprises a pair of crosshairs 61 and 63. A first crosshair 61 extends essentially vertically whilst a second crosshair 63 extends essentially horizontally. Note that the bullseye view also comprises two circles formed concentrically around an alignment point. The alignment point coincides with an intersection of the two crosshairs 61 and 63. In other examples, the navigation view does not comprise such circles but comprises at least one of the crosshairs 61 and 63.
The straight line defining the viewing direction 64 of the navigation view extends between the planned entry point 48 and the planned target point 52. The bullseye view is centered on the straight line. The alignment point lies on the straight line.
Also, the representation 58 of the tip of the surgical instrument 18 is shown. The representation 58 in this case is a two-dimensional projection of the tip of the surgical instrument 18 into a plane perpendicular to viewing direction. Still further, an indication 60 of a distance between the distal tip of the surgical instrument 18 and the target 50 (i.e., the target point 52) and an indication 62 of a lowest distance between the trajectory 56 and the target 50 (i.e., the target point 52) are shown. An additional indication of a relative spatial relationship between the recommended entry point (in this example the planned entry point 48) and the target 50 may also be shown.
It is apparent from
By continuously tracking the surgical instrument 18, the navigation view can be controlled by the processor 2 in near real-time. Controlling the navigation view preferably comprises determining the navigation view and triggering the display 4 to display the determined navigation view. As a result, the surgeon can be provided with an up-to date navigation view corresponding to the current pose of the surgical instrument.
It is apparent from
When comparing the navigation view of
In case a perspective view such as the one described above with reference to
After instantaneously changing the recommended entry point, it may be reset from the current entry point 66 to the planned entry point 48 upon the distance between the planned entry point 48 and the current entry point 48 no longer fulfilling a predefined criterion such as the predefined condition. Alternatively, the recommended entry point may be permanently changed from the planned entry point 48 to the current entry point 66, upon the distance between the planned entry point 48 and the current entry point 66 fulfilling the predefined condition.
In order to guide a surgeon to move the surgical instrument 18 so as to align the trajectory 56 with the straight line extending between the current entry point 66 and the planned target point 52, the navigation view shown in
The current entry point 66 shown in
Furthermore, the navigation view in this example comprises a progress bar 68 concentrically formed around the straight line between the current entry point 66 and the target point 52. The progress bar indicates a distance between the tip of the surgical instrument 18 and the planned target 50 (i.e., the planned target point 52). In particular, the progress bar 68 is an indication of a relationship between the distance between the tip of the surgical instrument 18 and the current entry point 66, and the distance between the current entry point 66 and the target point 52. The closer the tip of the surgical instrument 18 to the target 50 is, the fuller (i.e., the more complete) is the progress bar. In another variant, the progress bar may be referred to as a countdown bar. In this case, the closer the tip of the surgical instrument 18 to the target 50 is, the emptier (i.e., the less complete) is the progress bar.
Also provided is a computer-readable medium comprising a computer program comprising instructions which, when executed by a processor (i.e., the processor 2), causes the processor to carry out the method described herein. Furthermore, a data carrier signal carrying information which represent the computer program is provided.
As described with reference to the exemplary embodiments, the technique presented herein in some variants enables displaying visual cues to decompose a surgeon's task of aligning the surgical instrument 18 into two sequential tasks. In a first task, the front tip of the surgical instrument 18 is aligned with the planned entry point 48. Afterwards, in a second task, the surgical instrument 18 is aligned such that the trajectory 56 passes through the planned target 50.
The navigation view is for example a bullseye view looking along the actual instrument trajectory 56. The bullseye view can be displayed together with the perspective view described above, which is a two or three dimensional visualization of the computer model.
The perspective view may be oriented such that it best matches an actual perspective of a surgeon onto the patient 14 lying in front of him. The orientation of the perspective view may be determined based on information from the optical tracking system 6 or the electromagnetic tracking system 26, or from both. The orientation of the perspective view may be further determined based on at least one known coordinate transformation and/or a known surgeon position relative to an operating table on which the patient 14 is positioned. This visualization by the perspective view enables the surgeon to easily find the planned entry point 48 on the patient 14.
The bullseye view showing the representation 58 of the front tip of the surgical instrument 18 may also show an arbitrary proximal point of the surgical instrument's longitudinal axis 24. As shown in the examples of
The surgeon can then align the orientation of the surgical instrument 18 using the newly oriented bullseye view until the trajectory 56 passes through the target 50 as shown in
In most cases, it is more important to exactly hit the target point 52, whereas an offset of a few millimeters from the entry point 48 is usually inconsequential. This means that an alignment as shown in
This advantageous sequential alignment can be enabled by switching the navigation view from looking from the planned entry point 48 towards the target 50 to look from the current entry point 66 towards the target 50, once the current entry point 66 is “good enough”, so that the surgeon can then focus fully on correcting the alignment of the surgical instrument 18 with respect to the patient 14 so that the trajectory 56 hits the target 50.
The method described herein, which instantaneously changes the recommended entry point, has an advantage compared with simply orienting or aligning a bullseye view at the front tip of the surgical instrument 18 with a viewing direction looking towards the target 50, as it avoids indicating very large directional offsets when the tip comes near the target 50. Instead, the current entry point 66 can be considered as a pivot point about which the surgeon can make corrections to the orientation of the surgical instrument 18 and thus to the direction of the trajectory 56.
A combination of the perspective view, which is a surgeon-oriented two or three dimensional view, and the bullseye view may be displayed. Also, the bullseye view may be switched from looking from the planned entry point 48 towards the target 50 (
By instantaneously changing the recommended entry point from the planned entry point 48 to the current entry point 66, surgical navigation is improved. For example, a surgeon may not be able to or may decide to not position the surgical instrument 18 precisely on the planned entry point 48. In this case, a navigation view guiding the surgeon from the current entry point 66 to the target 50 may be advantageous. By only changing the recommended entry point to the current entry point 66 upon a distance between the current entry point 66 and the planned entry point 48 fulfilling a predetermined condition, it can be ensured that the trajectory 56 of the surgical instrument 18 is still sufficiently close to the planned trajectory 54.
The features described in relation to the exemplary embodiments shown in the drawings can be readily combined to result in different embodiments. It is apparent, therefore, that the present disclosure may be varied in many ways. Such variations are not to be regarded as a departure from the scope of the invention as defined by the claims appended hereto.
Number | Date | Country | Kind |
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20151338.9 | Jan 2020 | EP | regional |