Patent Grant
9139351
The United States Patent Office (USPTO) has published a notice to the effect that the USPTO's computer programs require that patent applicants reference both a serial number and indicate whether an application is a continuation, continuation-in-part, or divisional of a parent application. Stephen G. Kunin, Benefit of Prior-Filed Application, USPTO Official Gazette Mar. 18, 2003. The present Applicant Entity (hereinafter “Applicant”) has provided above a specific reference to the application(s) from which priority is being claimed as recited by statute. Applicant understands that the statute is unambiguous in its specific reference language and does not require either a serial number or any characterization, such as “continuation” or “continuation-in-part,” for claiming priority to U.S. patent applications. Notwithstanding the foregoing, Applicant understands that the USPTO's computer programs have certain data entry requirements, and hence Applicant has provided designation(s) of a relationship between the present application and its parent application(s) as set forth above, but expressly points out that such designation(s) are not to be construed in any way as any type of commentary and/or admission as to whether or not the present application contains any new matter in addition to the matter of its parent application(s).
Flexible connectors for use with substantially thermally sealed storage containers are described herein. In some embodiments, a substantially thermally sealed storage container includes a flexible connector joining an aperture in an exterior of a substantially thermally sealed storage container to an aperture in a substantially thermally sealed storage region within the container. In these embodiments, the flexible connector includes a duct forming an elongated thermal pathway between the exterior of the container and the substantially thermally sealed storage region, the duct substantially defining a conduit between the exterior of the substantially thermally sealed storage container and the aperture on the substantially thermally sealed storage region, a first compression unit configured to mate with a first end of the duct, a second compression unit configured to mate with a second end of the duct, and a plurality of compression strands connected between the first compression unit and the second compression unit.
In some embodiments, a substantially thermally sealed storage container includes an outer wall substantially defining a substantially thermally sealed storage container, the outer wall substantially defining a single outer wall aperture, an inner wall substantially defining a substantially thermally sealed storage region within the substantially thermally sealed storage container, the inner wall substantially defining a single inner wall aperture, a gap between the inner wall and the outer wall, at least one section of ultra efficient insulation material within the gap; and a flexible connector joining the single outer wall aperture and the single inner wall aperture. In these embodiments, the flexible connector includes a duct substantially defining a conduit including an extended thermal pathway, a first compression unit configured to mate with a first end of the duct, a second compression unit configured to mate with a second end of the duct, and a plurality of compression strands connected between the first compression unit and the second compression unit.
In some embodiments, a substantially thermally sealed storage container includes an outer wall substantially defining a substantially thermally sealed storage container, the outer wall substantially defining a single outer wall aperture, an inner wall substantially defining a substantially thermally sealed storage region within the substantially thermally sealed storage container, the inner wall substantially defining a single inner wall aperture, a gap between the inner wall and the outer wall, at least one layer of multilayer insulation material within the gap, the at least one layer of multilayer insulation material substantially surrounding the inner wall, a pressure less than or equal to 5×10−4 torr in the gap; and a flexible connector joining the single outer wall aperture and the single inner wall aperture. In these embodiments, the flexible connector includes a duct substantially defining a conduit including an extended thermal pathway, a first compression unit configured to mate with a first end of the duct, a second compression unit configured to mate with a second end of the duct, and a plurality of compression strands connecting the first compression unit and the second compression unit.
The foregoing summary is illustrative only and is not intended to be in any way limiting. In addition to the illustrative aspects, embodiments, and features described above, further aspects, embodiments, and features will become apparent by reference to the drawings and the following detailed description.
In the following detailed description, reference is made to the accompanying drawings, which form a part hereof. In the drawings, similar symbols typically identify similar components, unless context dictates otherwise. The illustrative embodiments described in the detailed description, drawings, and claims are not meant to be limiting. Other embodiments may be utilized, and other changes may be made, without departing from the spirit or scope of the subject matter presented here.
The use of the same symbols in different drawings typically indicates similar or identical items.
With reference now to
The substantially thermally sealed storage container 100 may be of a portable size and shape, for example a size and shape within expected portability estimates for an individual person. The substantially thermally sealed storage container 100 may be configured for both transport and storage of material. The substantially thermally sealed storage container 100 may be configured of a size and shape for carrying, lifting or movement by an individual person. For example, in some embodiments the substantially thermally sealed storage container 100 has a mass that is less than approximately 50 kilograms (kg), or less than approximately 30 kg. For example, in some embodiments a substantially thermally sealed storage container 100 has a length and width that are less than approximately 1 meter (m). For example, implementations of a substantially thermally sealed storage container 100 may include dimensions on the order of 45 centimeters (cm) in diameter and 70 cm in height. The substantially thermally sealed storage container 100 illustrated in
As shown in
In some embodiments the substantially thermally sealed storage container may include one or more heat sink units thermally connected to one or more storage region 130. In some embodiments, the substantially thermally sealed storage container 100 may include no heat sink units. In some embodiments, the substantially thermally sealed storage container 100 may include heat sink units within the interior of the container 100, such as within a storage region 130. The term “heat sink unit,” as used herein, includes one or more units that absorb thermal energy. See, for example, U.S. Pat. No. 5,390,734 to Voorhes et al., titled “Heat Sink,” U.S. Pat. No. 4,057,101 to Ruka et al., titled “Heat Sink,” U.S. Pat. No. 4,003,426 to Best et al., titled “Heat or Thermal Energy Storage Structure,” and U.S. Pat. No. 4,976,308 to Faghri titled “Thermal Energy Storage Heat Exchanger,” which are each incorporated herein by reference. Heat sink units may include, for example: units containing frozen water or other types of ice; units including frozen material that is generally gaseous at ambient temperature and pressure, such as frozen carbon dioxide (CO2); units including liquid material that is generally gaseous at ambient temperature and pressure, such as liquid nitrogen; units including artificial gels or composites with heat sink properties; units including phase change materials; and units including refrigerants. See, for example: U.S. Pat. No. 5,261,241 to Kitahara et al., titled “Refrigerant,” U.S. Pat. No. 4,810,403 to Bivens et al., titled “Halocarbon Blends for Refrigerant Use,” U.S. Pat. No. 4,428,854 to Enjo et al., titled “Absorption Refrigerant Compositions for Use in Absorption Refrigeration Systems,” and U.S. Pat. No. 4,482,465 to Gray, titled “Hydrocarbon-Halocarbon Refrigerant Blends,” which are each herein incorporated by reference.
As depicted in
Although the substantially thermally sealed storage container 100 depicted in
In some embodiments, a substantially thermally sealed container 100 includes at least one layer of nontoxic material on an interior surface of one or more substantially thermally sealed storage region 130. Nontoxic material may include, for example, material that does not produce residue that may be toxic to the contents of the at least one substantially thermally sealed storage region 130, or material that does not produce residue that may be toxic to the future users of contents of the at least one substantially thermally sealed storage region 130. Nontoxic material may include material that maintains the chemical structure of the contents of the at least one substantially thermally sealed storage region 130, for example nontoxic material may include chemically inert or non-reactive materials. Nontoxic material may include material that has been developed for use in, for example, medical, pharmaceutical or food storage applications. Nontoxic material may include material that may be cleaned or sterilized, for example material that may be irradiated, autoclaved, or disinfected. Nontoxic material may include material that contains one or more antibacterial, antiviral, antimicrobial, or antipathogen agents. For example, nontoxic material may include aldehydes, hypochlorites, oxidizing agents, phenolics, quaternary ammonium compounds, or silver. Nontoxic material may include material that is structurally stable in the presence of one or more cleaning or sterilizing compounds or radiation, such as plastic that retains its structural integrity after irradiation, or metal that does not oxidize in the presence of one or more cleaning or sterilizing compounds. Nontoxic material may include material that consists of multiple layers, with layers removable for cleaning or sterilization, such as for reuse of the at least one substantially thermally sealed storage region. Nontoxic material may include, for example, material including metals, fabrics, papers or plastics.
In some embodiments, a substantially thermally sealed container 100 includes at least one layer including at least one metal on an interior surface of at least one thermally sealed storage region 130. For example, the at least one metal may include gold, aluminum, copper, or silver. The at least one metal may include at least one metal composite or alloy, for example steel, stainless steel, metal matrix composites, gold alloy, aluminum alloy, copper alloy, or silver alloy. In some embodiments, the at least one metal includes metal foil, such as titanium foil, aluminum foil, silver foil, or gold foil. A metal foil may be a component of a composite, such as, for example, in association with polyester film, such as polyethylene terephthalate (PET) polyester film. The at least one layer including at least one metal on the interior surface of at least one storage region 130 may include at least one metal that may be sterilizable or disinfected. For example, the at least one metal may be sterilizable or disinfected using plasmons. For example, the at least one metal may be sterilizable or disinfected using autoclaving, thermal means, or chemical means. Depending on the embodiment, the at least one layer including at least one metal on the interior surface of at least one storage region may include at least one metal that has specific heat transfer properties, such as a thermal radiative properties.
In some embodiments, a substantially thermally sealed storage container 100 includes one or more storage structures within an interior of at least one thermally sealed storage region 130. For example, a storage structure may include racks, shelves, containers, thermal insulation, shock insulation, or other structures configured for storage of material within the storage region 130. In some embodiments, a substantially thermally sealed storage container 100 includes one or more removable inserts within an interior of at least one thermally sealed storage region 130. The removable inserts may be made of any material appropriate for the embodiment, including metal, alloy, composite, or plastic. The removable inserts may be made of any material appropriate for the embodiment, including nontoxic materials. The one or more removable inserts may include inserts that may be reused or reconditioned. The one or more removable inserts may include inserts that may be cleaned, sterilized, or disinfected as appropriate to the embodiment.
In some embodiments, the container 100 may be configured for storage of one or more medicinal units within a storage region 130. For example, some medicinal units are optimally stored within approximately 0 degrees Centigrade and approximately 10 degrees Centigrade. For example, some medicinal units are optimally stored within approximately 2 degrees Centigrade and approximately 8 degrees Centigrade. See: Chen and Kristensen, “Opportunities and Challenges of Developing Thermostable Vaccines,” Expert Rev. Vaccines, 8(5), pages 547-557 (2009); Matthias et al., “Freezing Temperatures in the Vaccine Cold Chain: A Systematic Literature Review,” Vaccine 25, pages 3980-3986 (2007); Wirkas et al., “A Vaccines Cold Chain Freezing Study in PNG Highlights Technology Needs for Hot Climate Countries,” Vaccine 25, pages 691-697 (2007); the WHO publication titled “Preventing Freeze Damage to Vaccines,” publication no. WHO/IVB/07.09 (2007); and the WHO publication titled “Temperature Sensitivity of Vaccines,” publication no. WHO/IVB/06.10 (2006), which are all herein incorporated by reference.
The term “medicinal”, as used herein, includes a drug, composition, formulation, material or compound intended for medicinal or therapeutic use. For example, a medicinal may include drugs, vaccines, therapeutics, vitamins, pharmaceuticals, remedies, homeopathic agents, naturopathic agents, or treatment modalities in any form, combination or configuration. For example, a medicinal may include vaccines, such as: a vaccine packaged as an oral dosage compound, vaccine within a prefilled syringe, a container or vial containing vaccine, vaccine within a unijet device, or vaccine within an externally deliverable unit (e.g. a vaccine patch for transdermal applications). For example, a medicinal may include treatment modalities, such as: antibody therapies, small-molecule compounds, anti-inflammatory agents, therapeutic drugs, vitamins, or pharmaceuticals in any form, combination or configuration. A medicinal may be in the form of a liquid, gel, solid, semi-solid, vapor, or gas. In some embodiments, a medicinal may be a composite. For example, a medicinal may include a bandage infused with antibiotics, anti-inflammatory agents, coagulants, neurotrophic agents, angiogenic agents, vitamins or pharmaceutical agents.
As depicted in
In some embodiments, a substantially thermally sealed storage container 100 may include one or more sections of an ultra efficient insulation material. In some embodiments, there is at least one section of ultra efficient insulation material within the gap 120. The term “ultra efficient insulation material,” as used herein, may include one or more type of insulation material with extremely low heat conductance and extremely low heat radiation transfer between the surfaces of the insulation material. The ultra efficient insulation material may include, for example, one or more layers of thermally reflective film, high vacuum, aerogel, low thermal conductivity bead-like units, disordered layered crystals, low density solids, or low density foam. In some embodiments, the ultra efficient insulation material includes one or more low density solids such as aerogels, such as those described in, for example: Fricke and Emmerling, Aerogels—preparation, properties, applications, Structure and Bonding 77: 37-87 (1992); and Pekala, Organic aerogels from the polycondensation of resorcinol with formaldehyde, Journal of Materials Science 24: 3221-3227 (1989), which are each herein incorporated by reference. As used herein, “low density” may include materials with density from about 0.01 g/cm3 to about 0.10 g/cm3, and materials with density from about 0.005 g/cm3 to about 0.05 g/cm3. In some embodiments, the ultra efficient insulation material includes one or more layers of disordered layered crystals, such as those described in, for example: Chiritescu et al., Ultralow thermal conductivity in disordered, layered WSe2 crystals, Science 315: 351-353 (2007), which is herein incorporated by reference. In some embodiments, the ultra efficient insulation material includes at least two layers of thermal reflective film separated, for example, by at least one of: high vacuum, low thermal conductivity spacer units, low thermal conductivity bead like units, or low density foam. In some embodiments, the ultra efficient insulation material may include at least two layers of thermal reflective material and at least one spacer unit between the layers of thermal reflective material. For example, the ultra-efficient insulation material may include at least one multiple layer insulating composite such as described in U.S. Pat. No. 6,485,805 to Smith et al., titled “Multilayer insulation composite,” which is herein incorporated by reference. For example, the ultra-efficient insulation material may include at least one metallic sheet insulation system, such as that described in U.S. Pat. No. 5,915,283 to Reed et al., titled “Metallic sheet insulation system,” which is herein incorporated by reference. For example, the ultra-efficient insulation material may include at least one thermal insulation system, such as that described in U.S. Pat. No. 6,967,051 to Augustynowicz et al., titled “Thermal insulation systems,” which is herein incorporated by reference. For example, the ultra-efficient insulation material may include at least one rigid multilayer material for thermal insulation, such as that described in U.S. Pat. No. 7,001,656 to Maignan et al., titled “Rigid multilayer material for thermal insulation,” which is herein incorporated by reference. For example, the ultra-efficient insulation material may include multilayer insulation material, or “MLI.” For example, an ultra efficient insulation material may include multilayer insulation material such as that used in space program launch vehicles, including by NASA. See, e.g., Daryabeigi, “Thermal analysis and design optimization of multilayer insulation for reentry aerodynamic heating,” Journal of Spacecraft and Rockets 39: 509-514 (2002), which is herein incorporated by reference. For example, the ultra efficient insulation material may include space with a partial gaseous pressure lower than atmospheric pressure external to the container 100. In some embodiments, the ultra efficient insulation material may substantially cover the inner wall 110 surface facing the gap 120. In some embodiments, the ultra efficient insulation material may substantially cover the outer wall 105 surface facing the gap 120. In some embodiments, the ultra efficient insulation material may substantially fill the gap 120.
In some embodiments, there is at least one layer of multilayer insulation material within the gap 120, wherein the at least one layer of multilayer insulation material substantially surrounds the inner wall 110. In some embodiments, there are a plurality of layers of multilayer insulation material within the gap 120, therein the layers may not be homogeneous. In some embodiments there may be one or more additional layers within or in addition to the ultra efficient insulation material, such as, for example, an outer structural layer or an inner structural layer. An inner or an outer structural layer may be made of any material appropriate to the embodiment, for example an inner or an outer structural layer may include: plastic, metal, alloy, composite, or glass. In some embodiments, there may be one or more layers of high vacuum between layers of thermal reflective film. In some embodiments, the gap 120 includes a substantially evacuated gaseous pressure relative to the atmospheric pressure external to the container 100. For example, in some embodiments the gap 120 includes substantially evacuated space having a pressure less than or equal to 1×10−2 torr. For example, in some embodiments the gap 120 includes substantially evacuated space having a pressure less than or equal to 5×10−4 torr. For example, in some embodiments the gap 120 includes a pressure less than or equal to 1×10−2 torr in the gap 120. For example, in some embodiments the gap 120 includes a pressure less than or equal to 5×10−4 torr in the gap 120. In some embodiments, the gap 120 includes a pressure less than 1×10−2 torr, for example, less than 5×10−3 torr, 5×10−4 torr, 5×10−5 torr, 5×10−6 torr or 5×10−7 torr. For example, in some embodiments the gap 120 includes a plurality of layers of multilayer insulation material and substantially evacuated space having a pressure less than or equal to 1×10−2 torr. For example, in some embodiments the gap 120 includes a plurality of layers of multilayer insulation material and substantially evacuated space having a pressure less than or equal to 5×10−4 torr.
The substantially thermally sealed storage container 100 includes a flexible connector 115 joining an aperture in an exterior of a substantially thermally sealed storage container 100 to an aperture in a substantially thermally sealed storage region 130 within the container. The container 110 includes a flexible connector 115 joining the edge of the single outer wall aperture and the edge of the single inner wall aperture. As illustrated in
A flexible connector 115 is flexible along its length, or vertically as depicted in
The flexible connector 115 includes a duct forming an elongated thermal pathway 160 between the exterior of the container 100 and the substantially thermally sealed storage region 130, the duct substantially defining a conduit 125 between the exterior of the substantially thermally sealed storage container 100 and the aperture to the substantially thermally sealed storage region 130. The flexible connector 115 includes a first compression unit 150 configured to mate with a first end of the duct, a second compression unit 140 configured to mate with a second end of the duct, and a plurality of compression strands 145 connected between the first compression unit 150 and the second compression unit 140. In some embodiments, the first compression unit 150 substantially encircles the first end of the duct. In some embodiments, the second compression unit 140 substantially encircles the second end of the duct. As illustrated in
The flexible connector 115 may be fabricated from a variety of materials, depending on the embodiment. For example, the flexible connector 115 may be fabricated from materials with particular densities, strength, resilience or thermal conduction properties as appropriate to the embodiment. In some embodiments, the flexible connector 115 is fabricated from stainless steel. In some embodiments, the flexible connector 115 is fabricated from plastics. In some embodiments, the duct is fabricated from stainless steel. In some embodiments, the first compression unit is fabricated from stainless steel. In some embodiments, the second compression unit is fabricated from stainless steel. In some embodiments, the plurality of compression strands are fabricated from stainless steel.
Depending on the embodiment, a substantially thermally sealed storage container 100 may be fabricated from a variety of materials. For example, a substantially thermally sealed storage container 100 may be fabricated from metals, fiberglass or plastics of suitable characteristics for a given embodiment. For example, a substantially thermally sealed storage container 100 may include materials of a suitable strength, hardness, durability, cost, availability, thermal conduction characteristics, gas-emitting properties, or other considerations appropriate for a given embodiment. In some embodiments, the outer wall 105 is fabricated from stainless steel. In some embodiments, the outer wall 105 is fabricated from aluminum. In some embodiments, the inner wall 110 is fabricated from stainless steel. In some embodiments, the inner wall 110 is fabricated from aluminum. In some embodiments, the flexible connector 115 is fabricated from stainless steel. In some embodiments, portions or parts of a substantially thermally sealed storage container 100 may be fabricated from composite or layered materials. For example, an outer wall 105 may be substantially be fabricated from stainless steel, with an external covering of plastic. For example, an inner wall 110 may substantially be fabricated from stainless steel, with a coating within the substantially sealed storage region 130 of plastic, rubber, foam or other material suitable to provide support and insulation to material stored within the substantially sealed storage region 130.
In embodiments with an inner wall 110 and/or an outer wall 105 fabricated from one or more materials and a flexible connector 115 fabricated from one or more different materials, one or more junction units 155, 135 may be included in the substantially thermally sealed storage container 100 to ensure a suitably strong, durable and/or gas-impermeable connection between the inner wall 110 and the flexible connector 115 and/or the outer wall 105 and the flexible connector 115. A “junction unit,” as used herein, includes a unit configured for connections to two different components of the container 100, forming a junction between the different components. A substantially thermally sealed container 100 may include a gas-impermeable junction between the first end of the duct and the outer wall at the edge of the outer wall aperture. A substantially thermally sealed container 100 may include a gas-impermeable junction between the second end of the duct and the inner wall at the edge of the inner wall aperture. Some embodiments include a gas-impermeable junction between the second end of the duct and the substantially thermally sealed storage region 130, the gas-impermeable junction substantially encircling the aperture in the substantially thermally sealed storage region 130. For example, in embodiments with a inner wall 110 and/or an outer wall 105 fabricated from aluminum and a flexible connector 115 fabricated from stainless steel, one or more junction units 155, 135 may be included in the substantially thermally sealed storage container 100 to ensure a suitably strong and gas-impermeable attachment between the inner wall 110 and the flexible connector 115 and/or the outer wall 105 and the flexible connector 115. Some embodiments include a gas-impermeable junction between the first end of the duct and the exterior of the substantially thermally sealed storage container 100, the gas-impermeable junction substantially encircling the aperture in the exterior. For example, as depicted in
In some embodiments, additional supporting units may be included in the gap 120 to provide additional support to the inner wall 110 in addition to that provided by the flexible connector 115. For example, there may be one or more thermally non-conductive strands attached to the surface of the outer wall 105 facing the gap 120, wherein the thermally non-conductive strands are configured to extend around the surface of the inner wall 110 facing the gap 120 and provide additional support or movement restraint on the inner wall 110 and, by extension, the contents of the substantially thermally sealed storage region 130. In some embodiments, the central regions of the plurality of strands wrap around the inner wall 110 at diverse angles, with the corresponding ends of each of the plurality of strands fixed to the surface of the outer wall 105 facing the gap 120 at multiple locations. One or more thermally non-conductive strands may be, for example, fabricated from fiberglass strands or ropes. One or more thermally non-conductive strands may be, for example, fabricated from stainless steel strands or ropes. One or more thermally non-conductive strands may be, for example, fabricated from strands of a para-aramid synthetic fiber, such as Kevlar™. A plurality of thermally non-conductive strands may be attached to the surface of the outer wall 105 facing the gap 120 at both ends, with the center of the strands wrapped around the surface of the inner wall 110 facing the gap 120. For example, a plurality of strands fabricated from stainless steel ropes may be attached to the surface of the outer wall 105 facing the gap 120 at both ends, with the center of the strands wrapped around the surface of the inner wall 110 facing the gap 120.
As illustrated in
The flexible connector 115 is fabricated with sufficient flexibility, both in its horizontal and vertical directions, to allow the inner wall 110 to be positioned adjacent to the outer wall 105 at one or more contact points 800, 810. The flexible connector 115 is fabricated with sufficient flexibility, both in its horizontal and vertical directions, to allow the inner wall 110 to move to a position adjacent to the outer wall 105 while maintaining the structural integrity of the junctions between the flexible connector 115 and the outer wall 105 as well as the inner wall 110. The structural integrity of the junctions between the flexible connector 115 and the outer wall 105 and the inner wall 110 should be maintained to the degree required to maintain the thermal capabilities of the container 100 when it is realigned to an upright position. For example, in embodiments wherein the gap 120 between the outer wall 105 and the inner wall 110 contains substantially evacuated space, the junctions between the flexible connector 115 and the outer wall 105 and the inner wall 110 should be maintained as required to maintain the substantially evacuated space. For example, in embodiments wherein the gap 120 between the outer wall 105 and the inner wall 110 contains material with thermal properties that are dependent on anhydrous conditions, the junctions between the flexible connector 115 and the outer wall 105 and the inner wall 105 should be maintained as required to maintain anhydrous conditions within the gap 120. The flexible connector 115 is fabricated with sufficient flexibility, both in its horizontal and vertical directions, to allow the flexible connector to resume its usual position when the container 100 is placed in an upright position (e.g. as in
The restriction units 930, 900, 910 may be fabricated from a material of suitable strength, resilience and durability for a given embodiment, such as rubber, plastics, metals, or other materials. The restriction units 930, 900, 910 may be fabricated from materials with low thermal conduction properties so as to provide minimal thermal conduction between the inner wall 110 and the outer wall 105 when the inner wall 110 is positioned adjacent to one or more restriction units 930, 900, 910. In some embodiments, one or more restriction units 930, 900, 910 may be fabricated from a composite material, or a layer of materials, such as stainless steel overlaid with a softer plastic layer.
Some embodiments may include a substantially thermally sealed storage container including one or more temperature indicators. For example, at least one temperature indicator may be located within a substantially thermally sealed storage region, at least one temperature indicator may be located exterior to the container, or at least one temperature indicator may be located within the structure of the container. In some embodiments, multiple temperature indicators may be located in multiple positions. Temperature indicators may include temperature indicating labels, which may be reversible or irreversible. See, for example, the Environmental Indicators sold by ShockWatch Company, with headquarters in Dallas Tex., the Temperature Indicators sold by Cole-Palmer Company of Vernon Hills Ill. and the Time Temperature Indicators sold by 3M Company, with corporate headquarters in St. Paul Minn., the brochures for which are each hereby incorporated by reference. Temperature indicators may include time-temperature indicators, such as those described in U.S. Pat. Nos. 5,709,472 and 6,042,264 to Prusik et al., titled “Time-temperature indicator device and method of manufacture” and U.S. Pat. No. 4,057,029 to Seiter, titled “Time-temperature indicator,” which are each herein incorporated by reference. Temperature indicators may include, for example, chemically-based indicators, temperature gauges, thermometers, bimetallic strips, or thermocouples. See also the World Health Organization (WHO) document titled “Getting Started with Vaccine Vial Monitors; Vaccines and Biologicals” dated December 2002 and the WHO document titled “Getting Started with Vaccine Vial Monitors—Questions and Answers on Field Operations,” Technical Session on Vaccine Vial Monitors, Mar. 27, 2002, Geneva, which are herein incorporated by reference.
In some embodiments, a substantially thermally sealed container may include one or more sensors operably attached to the container. At least one sensor may be located within at least one substantially thermally sealed storage region, at least one sensor may be located exterior to the container, or at least one sensor may be located within the structure of the container. In some embodiments, multiple sensors may be located in multiple positions. In some embodiments, the one or more sensors includes at least one sensor of a gaseous pressure within one or more of the at least one storage region, sensor of a mass within one or more of the at least one storage region, sensor of a stored volume within one or more of the at least one storage region, sensor of a temperature within one or more of the at least one storage region, or sensor of an identity of an item within one or more of the at least one storage region. In some embodiments, at least one sensor may include a temperature sensor, such as, for example, chemical sensors, thermometers, bimetallic strips, or thermocouples. An substantially thermally sealed container may include one or more sensors such as a physical sensor component such as described in U.S. Pat. No. 6,453,749 to Petrovic et al., titled “Physical sensor component,” which is herein incorporated by reference. An substantially thermally sealed container may include one or more sensors such as a pressure sensor such as described in U.S. Pat. No. 5,900,554 to Baba et al., titled “Pressure sensor,” which is herein incorporated by reference. An substantially thermally sealed container may include one or more sensors such as a vertically integrated sensor structure such as described in U.S. Pat. No. 5,600,071 to Sooriakumar et al., titled “Vertically integrated sensor structure and method,” which is herein incorporated by reference. An substantially thermally sealed container may include one or more sensors such as a system for determining a quantity of liquid or fluid within a container, such as described in U.S. Pat. No. 5,138,559 to Kuehl et al., titled “System and method for measuring liquid mass quantity,” U.S. Pat. No. 6,050,598 to Upton, titled “Apparatus for and method of monitoring the mass quantity and density of a fluid in a closed container, and a vehicular air bag system incorporating such apparatus,” and U.S. Pat. No. 5,245,869 to Clarke et al., titled “High accuracy mass sensor for monitoring fluid quantity in storage tanks,” which are each herein incorporated by reference. An substantially thermally sealed container may include one or more sensors of radio frequency identification (“RFID”) tags to identify material within the at least one substantially thermally sealed storage region. RFID tags are well known in the art, for example in U.S. Pat. No. 5,444,223 to Blama, titled “Radio frequency identification tag and method,” which is herein incorporated by reference.
In some embodiments, a substantially thermally sealed container may include one or more communications devices. The one or more communications devices, may include, for example, one or more recording devices, one or more transmission devices, one or more display devices, or one or more receivers. Communications devices may include, for example, communication devices that allow a user to detect information about the container visually, auditorily, or via signal to a remote device. Some embodiments may include communications devices on the exterior of the container, including devices attached to the exterior of the container, devices adjacent to the exterior of the container, or devices located at a distance from the exterior of the container. Some embodiments may include communications devices located within the structure of the container. Some embodiments may include communications devices located within at least one of the one or more substantially thermally sealed storage regions. Some embodiments may include at least one display device located at a distance from the container, for example a display located at a distance operably linked to at least one sensor. Some embodiments may include more than one type of communications device, and in some embodiments the devices may be operably linked. For example, some embodiments may contain both a receiver and an operably linked transmission device, so that a signal may be received by the receiver which then causes a transmission to be made from the transmission device. Some embodiments may include more than one type of communications device that are not operably linked. For example, some embodiments may include a transmission device and a display device, wherein the transmission device is not linked to the display device.
In some embodiments, a substantially thermally sealed storage container includes at least one authentication device, wherein the at least one authentication device may be operably connected to an aperture in the outer wall of the container. In some embodiments, a substantially thermally sealed storage container includes at least one authentication device, wherein the at least one authentication device may be operably connected to at least one externally-operable opening, control egress device, communications device, or other component. For example, an authentication device may include a device which may be authenticated with a key, or a device that may be authenticated with a code, such as a password or a combination. For example, an authentication device may include a device that may be authenticated using biometric parameters, such as fingerprints, retinal scans, hand spacing, voice recognition or biofluid composition (e.g. blood, sweat, or saliva).
In some embodiments, a substantially thermally sealed storage container includes at least one logging device. A logging device may be operably connected to an aperture in the outer wall of the container. In some embodiments, a substantially thermally sealed storage container includes at least one logging device, wherein the at least one logging device may be operably connected to at least one externally-operable opening, control egress device, communications device, or other component. The at least one logging device may be configured to log information desired by a user. For example, a logging device may include a record of authentication via the authentication device, such as a record of times of authentication, operation of authentication or individuals making the authentication. For example, a logging device may record that an authentication device was authenticated with a specific code which identifies a specific individual at one or more specific times. For example, a logging device may record egress of a quantity of a material from at least one storage region, such as recording that some quantity or units of material egressed at a specific time. For example, a logging device may record information from one or more sensors, one or more temperature indicators, or one or more communications devices.
In some embodiments an substantially thermally sealed container may include one or more recording devices. The one or more recording devices may include devices that are magnetic, electronic, chemical, or transcription based recording devices. One or more recording device may be located within at least one substantially thermally sealed storage region, one or more recording device may be located exterior to the container, or one or more recording device may be located within the structure of the container. The one or more recording device may record, for example, the temperature from one or more temperature sensor, data or information from one or more temperature indicator, or the gaseous pressure, mass, volume or identity of an item information from at least one sensor within the at least one storage region. In some embodiments, the one or more recording devices may be integrated with one or more sensor. For example, in some embodiments there may be one or more temperature sensors which record the highest, lowest or average temperature detected. For example, in some embodiments, there may be one or more mass sensors which record one or more mass changes within the container over time. For example, in some embodiments, there may be one or more gaseous pressure sensors which record one or more gaseous pressure changes within the container over time.
In some embodiments an substantially thermally sealed container may include one or more transmission device. One or more transmission device may be located within at least one substantially thermally sealed storage region, one or more transmission device may be located exterior to the container, or one or more transmission device may be located within the structure of the container. The one or more transmission device may transmit any signal or information, for example, the temperature from one or more temperature sensor, or the gaseous pressure, mass, volume or identity of an item or information from at least one sensor within the at least one storage region. In some embodiments, the one or more transmission device may be integrated with one or more sensor, or one or more recording device. The one or more transmission devices may transmit by any means known in the art, for example, but not limited to, via radio frequency (e.g. RFID tags), magnetic field, electromagnetic radiation, electromagnetic waves, sonic waves, or radioactivity.
In some embodiments, a substantially thermally sealed container may include one or more receivers. For example, one or more receivers may include devices that detect sonic waves, electromagnetic waves, radio signals, electrical signals, magnetic pulses, or radioactivity. Depending on the embodiment, one or more receiver may be located within one or more of the at least one substantially thermally sealed storage region. In some embodiments, one or more receivers may be located within the structure of the container. In some embodiments, the one or more receivers may be located on the exterior of the container. In some embodiments, the one or more receiver may be operably coupled to another device, such as for example one or more display devices, recording devices or transmission devices. For example, a receiver may be operably coupled to a display device on the exterior of the container so that when an appropriate signal is received, the display device indicates data, such as time or temperature data. For example, a receiver may be operable coupled to a transmission device so that when an appropriate signal is received, the transmission device transmits data, such as location, time, or positional data.
A flexible connector, similar to that illustrated in
A duct of 5 inches in length and fabricated in stainless steel was obtained from Ameriflex Inc., (Corona, Calif.). The duct was approximately 5 inches in total length prior to incorporation in the flexible connector. The duct included a central “bellows” region including approximately 10 corrugated folds at right angles to the central axis of the conduit formed by the duct. When the flexible connector is used in a substantially upright container (e.g. see
Two compression units were fabricated to substantially encircle each end region of the duct and to be adjacent to the bellows region of the duct when the flexible connector was assembled. Each compression unit was a disk-like structure with a central aperture configured to encircle an end region of the duct. See
Six wire ropes were used as compression strands to connect the first compression unit to the second compression unit. The compression units were connected in a substantially parallel orientation, with the wire ropes at right angles to the compression units. Each of the wire ropes was a 1×7 strand rope of approximately 0.03 inch diameter fabricated from US SAE 304 stainless steel. Each wire rope was rated to a break strength of 150 pounds by the manufacturer.
To assemble the flexible connector, the first compression unit was placed around the first end of the duct, and the second compression unit was placed around the second end of the duct.
After assembly, the flexible connector had a total length of approximately 4.85 inches and formed an internal conduit of approximately three inches in diameter. A total of six wire ropes were positioned at equal intervals connecting the first compression unit to the second compression unit. The wire ropes were substantially parallel to the internal conduit formed by the flexible connector. Although the wire ropes were substantially parallel to the internal conduit formed by the flexible connector, a small deformation of the wire ropes inward towards the duct was formed by the crimping of the crimp sleeves and associated tension on the wire ropes. The first compression unit and the second compression unit were substantially parallel to each other and substantially perpendicular to the internal conduit formed by the flexible connector.
A flexible connector was tested to establish its load bearing ability in an orientation substantially along the length of the internal conduit formed by the flexible connector. This is the expected orientation of a flexible connector relative to the storage region when the container is in an upright position (e.g. see
Two stainless steel compression units were connected with six stainless steel wire ropes as described in Example 1, only without the duct included in the structure. For purposes of testing, two compression units were connected with six wire ropes as described in Example 1, in the absence of a duct. For purposes of testing, two compression units and the set of compression strands connecting the compression units were used to approximate a complete flexible connector. The two compression units were positioned at the same approximate distance from each other as they would during fabrication of a flexible connector, as described in Example 1 (i.e. approximately 2.85 inches apart). The first compression unit was fixed to a stainless steel plate suspended from an industrial scale. A second stainless steel plate was attached to the second compression unit, with a steel chain suspended downward from the second steel plate. Weights were added steel chain suspended downward from the second steel plate in increasing increments, and the total mass suspended was evaluated using the reading of the industrial scale. Weights continued to be added until the wire ropes came apart. For a total of 6 stainless steel 1×7 strand ropes of approximately 0.03 inch diameter fabricated from US SAE 304 stainless steel, the failure point was determined as approximately 800 pounds. The crimp connections held firm and did not come apart during testing. On the basis of this test, it was estimated that a similarly-fabricated flexible neck unit installed within a substantially thermally sealed container would have the capacity to support approximately 800 pounds from a combination of the inner wall, the contents of the storage structure, and any net force from a partial pressure within a gap when the container is in an upright configuration.
All of the above U.S. patents, U.S. patent application publications, U.S. patent applications, foreign patents, foreign patent applications and non-patent publications referred to in this specification and/or listed in any Application Data Sheet, are incorporated herein by reference, to the extent not inconsistent herewith.
One skilled in the art will recognize that the herein described components (e.g., operations), devices, objects, and the discussion accompanying them are used as examples for the sake of conceptual clarity and that various configuration modifications are contemplated. Consequently, as used herein, the specific exemplars set forth and the accompanying discussion are intended to be representative of their more general classes. In general, use of any specific exemplar is intended to be representative of its class, and the non-inclusion of specific components (e.g., operations), devices, and objects should not be taken limiting.
With respect to the use of substantially any plural and/or singular terms herein, those having skill in the art can translate from the plural to the singular and/or from the singular to the plural as is appropriate to the context and/or application. The various singular/plural permutations are not expressly set forth herein for sake of clarity.
While particular aspects of the present subject matter described herein have been shown and described, it will be apparent to those skilled in the art that, based upon the teachings herein, changes and modifications may be made without departing from the subject matter described herein and its broader aspects and, therefore, the appended claims are to encompass within their scope all such changes and modifications as are within the true spirit and scope of the subject matter described herein. It will be understood by those within the art that, in general, terms used herein, and especially in the appended claims (e.g., bodies of the appended claims) are generally intended as “open” terms (e.g., the term “including” should be interpreted as “including but not limited to,” the term “having” should be interpreted as “having at least,” the term “includes” should be interpreted as “includes but is not limited to,” etc.). It will be further understood by those within the art that if a specific number of an introduced claim recitation is intended, such an intent will be explicitly recited in the claim, and in the absence of such recitation no such intent is present. For example, as an aid to understanding, the following appended claims may contain usage of the introductory phrases “at least one” and “one or more” to introduce claim recitations. However, the use of such phrases should not be construed to imply that the introduction of a claim recitation by the indefinite articles “a” or “an” limits any particular claim containing such introduced claim recitation to claims containing only one such recitation, even when the same claim includes the introductory phrases “one or more” or “at least one” and indefinite articles such as “a” or “an” (e.g., “a” and/or “an” should typically be interpreted to mean “at least one” or “one or more”); the same holds true for the use of definite articles used to introduce claim recitations. In addition, even if a specific number of an introduced claim recitation is explicitly recited, those skilled in the art will recognize that such recitation should typically be interpreted to mean at least the recited number (e.g., the bare recitation of “two recitations,” without other modifiers, typically means at least two recitations, or two or more recitations). Furthermore, in those instances where a convention analogous to “at least one of A, B, and C, etc.” is used, in general such a construction is intended in the sense one having skill in the art would understand the convention (e.g., “a system having at least one of A, B, and C” would include but not be limited to systems that have A alone, B alone, C alone, A and B together, A and C together, B and C together, and/or A, B, and C together, etc.). In those instances where a convention analogous to “at least one of A, B, or C, etc.” is used, in general such a construction is intended in the sense one having skill in the art would understand the convention (e.g., “a system having at least one of A, B, or C” would include but not be limited to systems that have A alone, B alone, C alone, A and B together, A and C together, B and C together, and/or A, B, and C together, etc.). It will be further understood by those within the art that typically a disjunctive word and/or phrase presenting two or more alternative terms, whether in the description, claims, or drawings, should be understood to contemplate the possibilities of including one of the terms, either of the terms, or both terms unless context dictates otherwise. For example, the phrase “A or B” will be typically understood to include the possibilities of “A” or “B” or “A and B.”
The herein described subject matter sometimes illustrates different components contained within, or connected with, different other components. It is to be understood that such depicted architectures are merely exemplary, and that in fact many other architectures may be implemented which achieve the same functionality. In a conceptual sense, any arrangement of components to achieve the same functionality is effectively “associated” such that the desired functionality is achieved. Hence, any two components herein combined to achieve a particular functionality can be seen as “associated with” each other such that the desired functionality is achieved, irrespective of architectures or intermedial components. Likewise, any two components so associated can also be viewed as being “operably connected”, or “operably coupled,” to each other to achieve the desired functionality, and any two components capable of being so associated can also be viewed as being “operably couplable,” to each other to achieve the desired functionality. Specific examples of operably couplable include but are not limited to physically mateable and/or physically interacting components.
While various aspects and embodiments have been disclosed herein, other aspects and embodiments will be apparent to those skilled in the art. The various aspects and embodiments disclosed herein are for purposes of illustration and are not intended to be limiting, with the true scope and spirit being indicated by the following claims.
The present application is related to and claims the benefit of the earliest available effective filing date(s) from the following listed application(s) (the “Related Applications”) (e.g., claims earliest available priority dates for other than provisional patent applications or claims benefits under 35 USC §119(e) for provisional patent applications, for any and all parent, grandparent, great-grandparent, etc. applications of the Related Application(s)). All subject matter of the Related Applications and of any and all parent, grandparent, great-grandparent, etc. applications of the Related Applications, including any priority claims, is incorporated herein by reference to the extent such subject matter is not inconsistent herewith. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/001,757, entitled TEMPERATURE-STABILIZED STORAGE CONTAINERS, naming Roderick A. Hyde; Edward K. Y. Jung; Nathan P. Myhrvold; Clarence T. Tegreene; William H. Gates, III; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Dec. 11, 2007, which is currently co-pending, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/006,088, entitled TEMPERATURE-STABILIZED STORAGE CONTAINERS WITH DIRECTED ACCESS, naming Roderick A. Hyde; Edward K. Y. Jung; Nathan P. Myhrvold; Clarence T. Tegreene; William H. Gates, III; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Dec. 27, 2007 now U.S. Pat. No. 8,215,518, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/006,089, entitled TEMPERATURE-STABILIZED STORAGE SYSTEMS, naming Roderick A. Hyde; Edward K. Y. Jung; Nathan P. Myhrvold; Clarence T. Tegreene; William H. Gates, III; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Dec. 27, 2007, which is currently co-pending, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/008,695, entitled TEMPERATURE-STABILIZED STORAGE CONTAINERS FOR MEDICINALS, naming Roderick A. Hyde; Edward K. Y. Jung; Nathan P. Myhrvold; Clarence T. Tegreene; William H. Gates, III; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Jan. 10, 2008 now U.S. Pat. No. 8,377,033, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/012,490, entitled METHODS OF MANUFACTURING TEMPERATURE-STABILIZED STORAGE CONTAINERS, naming Roderick A. Hyde; Edward K. Y. Jung; Nathan P. Myhrvold; Clarence T. Tegreene; William H. Gates, III; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Jan. 31, 2008 now U.S. Pat. No. 8,069,680, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/077,322, entitled TEMPERATURE-STABILIZED MEDICINAL STORAGE SYSTEMS, naming Roderick A. Hyde; Edward K. Y. Jung; Nathan P. Myhrvold; Clarence T. Tegreene; William Gates; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Mar. 17, 2008 now U.S. Pat. No. 8,215,835, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/152,465, entitled STORAGE CONTAINER INCLUDING MULTI-LAYER INSULATION COMPOSITE MATERIAL HAVING BANDGAP MATERIAL AND RELATED METHODS, naming Jeffrey A. Bowers; Roderick A. Hyde; Muriel Y. Ishikawa; Edward K. Y. Jung; Jordin T. Kare; Eric C. Leuthardt; Nathan P. Myhrvold; Thomas J. Nugent Jr.; Clarence T. Tegreene; Charles Whitmer; and Lowell L. Wood Jr. as inventors, filed May 13, 2008 now U.S. Pat. No. 8,485,387, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/152,467, entitled MULTI-LAYER INSULATION COMPOSITE MATERIAL INCLUDING BANDGAP MATERIAL, STORAGE CONTAINER USING SAME, AND RELATED METHODS, naming Jeffrey A. Bowers; Roderick A. Hyde; Muriel Y. Ishikawa; Edward K. Y. Jung; Jordin T. Kare; Eric C. Leuthardt; Nathan P. Myhrvold; Thomas J. Nugent Jr.; Clarence T. Tegreene; Charles Whitmer; and Lowell L. Wood Jr. as inventors, filed May 13, 2008 now U.S. Pat. No. 8,211,516, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/220,439, entitled MULTI-LAYER INSULATION COMPOSITE MATERIAL HAVING AT LEAST ONE THERMALLY-REFLECTIVE LAYER WITH THROUGH OPENINGS, STORAGE CONTAINER USING SAME, AND RELATED METHODS, naming Roderick A. Hyde; Muriel Y. Ishikawa; Jordin T. Kare; and Lowell L. Wood, Jr. as inventors, filed Jul. 23, 2008 now U.S. Pat. No. 8,603,598, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/658,579, entitled TEMPERATURE-STABILIZED STORAGE SYSTEMS, naming Geoffrey F. Deane; Lawrence Morgan Fowler; William Gates; Zihong Guo; Roderick A. Hyde; Edward K. Y. Jung; Jordin T. Kare; Nathan P. Myhrvold; Nathan Pegram; Nels R. Peterson; Clarence T. Tegreene; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Feb. 8, 2010, which is currently co-pending, or is an application of which a currently co-pending application is entitled to the benefit of the filing date. For purposes of the USPTO extra-statutory requirements, the present application constitutes a continuation-in-part of U.S. patent application Ser. No. 12/927,982, entitled TEMPERATURE-STABILIZED STORAGE SYSTEMS INCLUDING STORAGE STRUCTURES CONFIGURED FOR INTERCHANGEABLE STORAGE OF MODULAR UNITS, naming Geoffrey F. Deane; Lawrence Morgan Fowler; William Gates; Jenny Ezu Hu; Roderick A. Hyde; Edward K. Y. Jung; Jordin T. Kare; Nathan P. Myhrvold; Nathan Pegram; Nels R. Peterson; Clarence T. Tegreene; Charles Whitmer; and Lowell L. Wood, Jr. as inventors, filed Nov. 29, 2010, which is currently co-pending, or is an application of which a currently co-pending application is entitled to the benefit of the filing date.
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| Number | Date | Country | |
|---|---|---|---|
| 20110155745 A1 | Jun 2011 | US |
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